Abstract:
INTRODUCTION:Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma (SCC). Because of its rarity, both clinical and prognostic features of this variant are not well known. OBJECTIVE:In this study, we aimed to determine the frequency of BSCC and other SCC variants among all laryngeal SCC cases, and to determine clinical and prognostic features of BSCC variant. STUDY DESIGN:retrospective cohort study. Evidence level: Level 2b. MATERIAL AND METHODS:Records of the patients who had laryngeal SCC surgically treated at our institute between 2007 and 2013 were retrospectively reviewed. RESULTS:Among 198 subjects who had laryngeal SCC surgically treated, the frequency of the variants of SCC other than classical variant was 10.1% (20/198). The most common SCC variant was BSCC (6.6%). Eleven (84.6%) patients with BSCC were at an advanced stage at the presentation (p > 0.05). The 3-year overall survival and disease-free survival rates were 63% and 53% respectively. CONCLUSION:BSCC variant may be more common than previously reported. Since almost the half of patients experiences disease recurrence in the early period, multimodal treatment strategies should be employed at initial treatment, and a close follow-up is strongly recommended for this aggressive SCC variant.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Tutar H,Aydil U,Ekinci O,Bakkal FK,Tutar VB,Kizil Y,Ugur MBdoi
10.1016/j.bjorl.2014.02.005subject
Has Abstractpub_date
2014-05-01 00:00:00pages
245-50issue
3eissn
1808-8694issn
1808-8686pii
S1808-8694(14)00019-6journal_volume
80pub_type
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:/S0034-72992005000300014
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