Abstract:
BACKGROUND:There is limited information on caregiver outcomes of patients with treatment-resistant schizophrenia (TRS). AIM:This study aimed to evaluate the impact of short-term treatment with clozapine (i.e. 3 months) on caregiver burden, expressed emotions, caregiver abuse, and psychological morbidity among the caregivers in patients with TRS. 52 caregivers of patients with TRS were evaluated on the Family Burden Interview Schedule, Perceived Criticism Measure, Caregiver Abuse Screening Questionnaire, and General Health Questionnaire-12. RESULTS:Maximum caregiver burden was seen in the domain of disruption of routine family activities, and this was followed by the domains of disruption of family leisure, disruption of family interaction, and the effect on mental health on others. At the baseline assessment, three-fourth of the caregivers scored ≥12 on the objective burden. With 3 months of clozapine therapy, there was a significant reduction in the caregiver burden in all the domains of objective burden, subjective burden, and the global objective burden as per the clinician rating, in the expressed emotions as per both patients and the caregivers, caregiver abuse, and psychological morbidity among the caregivers. CONCLUSION:To conclude, this study suggests that caregivers of patients with TRS, experience significantly higher caregiver burden, and a large proportion of them suffer from psychological morbidity and indulge in expressed emotions and abuse of the patient. Treatment with clozapine for 3 months leads to a reduction in the caregiver burden, expressed emotions, caregiver abuse, and psychological morbidity among the caregivers.
journal_name
Nord J Psychiatryjournal_title
Nordic journal of psychiatryauthors
Verma M,Grover S,Chakrabarti Sdoi
10.1080/08039488.2020.1804617subject
Has Abstractpub_date
2021-02-01 00:00:00pages
118-123issue
2eissn
0803-9488issn
1502-4725journal_volume
75pub_type
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journal_title:Nordic journal of psychiatry
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doi:10.1080/08039488.2018.1463392
更新日期:2018-10-01 00:00:00
abstract::Studies conducted outside of Scandinavia indicate that most adolescents with substance misuse problems suffer from co-morbid mental disorders. The present study assessed the mental health of adolescents seeking help for substance misuse problems in a large Swedish city. Parents' mental health was also examined. The sa...
journal_title:Nordic journal of psychiatry
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doi:10.3109/08039488.2011.565798
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doi:10.3109/08039488.2011.644578
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journal_title:Nordic journal of psychiatry
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更新日期:2010-05-04 00:00:00
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