Pre-existing disease: the most important factor for health related quality of life long-term after critical illness: a prospective, longitudinal, multicentre trial.

abstract：INTRODUCTION:Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to desc...

journal_title：Critical care (London, England)

authors： Pearse RM,Harrison DA,James P,Watson D,Hinds C,Rhodes A,Grounds RM,Bennett ED

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the incidence of organ failure in trauma patients treated in an intensive care unit (ICU), and to study the relationship between organ failure and long-term survival and functional status. METHODS:This is a cohort study of all adult ICU trauma patients admitted to a unive...

journal_title：Critical care (London, England)

authors： Ulvik A,Kvåle R,Wentzel-Larsen T,Flaatten H

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...

journal_title：Critical care (London, England)

authors： Karmrodt J,David M,Yuan S,Markstaller K

更新日期：2006-01-01 00:00:00

abstract：:Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

journal_title：Critical care (London, England)

authors： Tomlinson LA,Forni LG

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants beyond the first post-natal week. The normal COP in healthy adult subjects (25 mmHg) is currently also applied as a reference value for healthy infants. This ...

journal_title：Critical care (London, England)

authors： Sussmane JB,de Soto M,Torbati D

更新日期：2001-10-01 00:00:00

abstract：INTRODUCTION:Monitoring of hemodynamic and volumetric parameters after severe burns is of critical importance. Pulmonary artery catheters, however, have been associated with many risks. Our aim was to show the feasibility of continuous monitoring with minimally invasive transpulmonary thermodilution (TPTD) in severely ...

journal_title：Critical care (London, England)

authors： Branski LK,Herndon DN,Byrd JF,Kinsky MP,Lee JO,Fagan SP,Jeschke MG

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Despite recommendations from professional societies and patient safety organizations, the majority of ICU patients worldwide are not routinely monitored for delirium, thus preventing timely prevention and management. The purpose of this systematic review is to summarize what types of implementation strateg...

journal_title：Critical care (London, England)

authors： Trogrlić Z,van der Jagt M,Bakker J,Balas MC,Ely EW,van der Voort PH,Ista E

更新日期：2015-04-09 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the clinical usefulness of open lung biopsy (OLB) in patients undergoing mechanical ventilation for diffuse pulmonary infiltrates of unknown etiology. METHODS:This was a 10-year retrospective study in a 10-bed medical intensive care unit. The medical records of 36 v...

journal_title：Critical care (London, England)

authors： Lim SY,Suh GY,Choi JC,Koh WJ,Lim SY,Han J,Lee KS,Shim YM,Chung MP,Kim H,Kwon OJ

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：:Experiencing treatment on a modern intensive care unit (ICU) is a potentially traumatic event. People who experience traumatic events have an increased risk of depression, anxiety disorders and post-traumatic stress disorder (PTSD). Extended follow-up has confirmed that many patients suffer physical and psychological ...

journal_title：Critical care (London, England)

authors： Hatch R,McKechnie S,Griffiths J

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Deregulated apoptosis and overshooting neutrophil functions contribute to immune and organ dysfunction in sepsis and multiple organ failure (MOF). In the present study, we determined the role of soluble Fas (sFas) in the regulation of posttraumatic neutrophil extrinsic apoptosis and the development of seps...

journal_title：Critical care (London, England)

authors： Paunel-Görgülü A,Flohé S,Scholz M,Windolf J,Lögters T

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Mottling around the knee, reflecting a reduced skin blood flow, is predictive of mortality in patients with septic shock. However, the causative pathophysiology of mottling remains unknown. We hypothesized that the cutaneous hypoperfusion observed in the mottled area is related to regional endothelial dysfun...

journal_title：Critical care (London, England)

authors： Bourcier S,Joffre J,Dubée V,Preda G,Baudel JL,Bigé N,Leblanc G,Levy BI,Guidet B,Maury E,Ait-Oufella H

更新日期：2017-06-23 00:00:00

abstract：BACKGROUND:Early survival following severe injury has been improved with refined resuscitation strategies. Multiple organ dysfunction syndrome (MODS) is common among this fragile group of patients leading to prolonged hospital stay and late mortality. MODS after trauma is widely attributed to dysregulated inflammation ...

journal_title：Critical care (London, England)

authors： Manson J,Cole E,De'Ath HD,Vulliamy P,Meier U,Pennington D,Brohi K

更新日期：2016-06-07 00:00:00

abstract：:The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners...

journal_title：Critical care (London, England)

authors： Broomhead LR,Brett SJ

更新日期：2002-10-01 00:00:00

abstract：:Urgent cardiac ultrasound examination in the critical care setting is clinically useful. Application of goal-directed echocardiography in this setting is quite distinct from typical exploratory diagnostic comprehensive echocardiography, because the urgent critical care setting mandates a goal-directed approach. Goal-d...

journal_title：Critical care (London, England)

authors： Walley PE,Walley KR,Goodgame B,Punjabi V,Sirounis D

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Neurological deterioration after intracerebral hemorrhage (ICH) is thought to be closely related to increased intracranial pressure (ICP), decreased cerebral blood flow (CBF), and brain metabolism. Transcranial Doppler (TCD) is increasingly used as an indirect measure of ICP, and quantitative EEG (QEEG) can ...

journal_title：Critical care (London, England)

authors： Chen Y,Xu W,Wang L,Yin X,Cao J,Deng F,Xing Y,Feng J

更新日期：2018-02-20 00:00:00

abstract：:Progress in management of critically ill neurological patients has led to improved survival rates. However, severe residual neurological impairment, such as persistent coma, occurs in some survivors. This raises concerns about whether it is ethically appropriate to apply aggressive care routinely, which is also associ...

journal_title：Critical care (London, England)

authors： Weiss N,Galanaud D,Carpentier A,Naccache L,Puybasset L

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Some guidelines to prevent ventilator-associated pneumonia (VAP) do not establish a recommendation for the preferential use of either heat and moisture exchangers (HMEs) or heated humidifiers (HHs), while other guidelines clearly advocate the use of HMEs. The aim of this study was to determine the incidenc...

journal_title：Critical care (London, England)

authors： Lorente L,Lecuona M,Jiménez A,Mora ML,Sierra A

更新日期：2006-01-01 00:00:00

abstract：:Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assessed the effect of a procalcitonin (PCT)-guided antibiotic treatment on outcomes in acute lower respiratory trac...

journal_title：Critical care (London, England)

authors： Lisboa T,Salluh J,Povoa P

更新日期：2018-01-27 00:00:00

abstract：INTRODUCTION:Metformin-associated lactic acidosis (MALA) is a classic side effect of metformin and is known to be a severe disease with a high mortality rate. The treatment of MALA with dialysis is controversial and is the subject of many case reports in the literature. We aimed to assess the prevalence of MALA in a 16...

journal_title：Critical care (London, England)

authors： Peters N,Jay N,Barraud D,Cravoisy A,Nace L,Bollaert PE,Gibot S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Bloodstream infections are associated with high morbidity and mortality, both of which contribute substantially to healthcare costs. The effects of early administration of appropriate antimicrobials on the prognosis and timing of defervescence of bacteremic patients remain under debate. METHODS:In a 6-year ...

journal_title：Critical care (London, England)

authors： Lee CC,Lee CH,Yang CY,Hsieh CC,Tang HJ,Ko WC

更新日期：2019-11-20 00:00:00

abstract：:Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, i...

journal_title：Critical care (London, England)

authors： Berger D,Takala J

更新日期：2016-06-09 00:00:00

abstract：:This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show that high-dose vitamin C can prevent or restore microcirculatory flow impairment by inhibiting activation of...

journal_title：Critical care (London, England)

authors： Oudemans-van Straaten HM,Spoelstra-de Man AM,de Waard MC

更新日期：2014-08-06 00:00:00

abstract：:The European Clinical Trials Directive requires an informed consent from the patient or a proxy in drug trials. Although informed consent is a valuable tool to protect patients' rights in clinical trials, this requirement largely impedes research in critical care settings, and if pursued in this context, it does not p...

journal_title：Critical care (London, England)

authors： Berg RM,Møller K,Rossel PJ

更新日期：2011-01-01 00:00:00

abstract：: ...

journal_title：Critical care (London, England)

authors： Martin CM

更新日期：2018-11-03 00:00:00

abstract：:Adverse events affect approximately 3% to 12% of hospitalized patients. At least a third, but as many as half, of such events are considered preventable. Detection of these events requires investments of time and money. A report in a recent issue of Critical Care used the medical emergency team activation as a trigger...

journal_title：Critical care (London, England)

authors： Amaral AC,Shojania KG

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Dysbiosis of intestinal microbiota likely plays an important role in the development of gut-derived infections, making it a potential therapeutic target against sepsis. However, experience with fecal microbiota transplantation (FMT) in the treatment of sepsis and knowledge of the underlying mechanisms are ...

journal_title：Critical care (London, England)

authors： Li Q,Wang C,Tang C,He Q,Zhao X,Li N,Li J

更新日期：2015-02-09 00:00:00

abstract：:This review documents important progress made in 2013 in the field of critical care respirology, in particular with regard to acute respiratory failure and acute respiratory distress syndrome. Twenty-five original articles published in the respirology and critical care sections of Critical Care are discussed in the fo...

journal_title：Critical care (London, England)

authors： Curley GF,Slutsky AS

更新日期：2014-10-15 00:00:00

abstract：INTRODUCTION:Glutamine supplementation has beneficial effects on morbidity and mortality in critically ill patients, possibly in part through an attenuation of the proinflammatory cytokine response and a stimulation of heat shock protein (HSP)70. We infused either alanine-glutamine or saline during endotoxin challenge ...

journal_title：Critical care (London, England)

authors： Andreasen AS,Pedersen-Skovsgaard T,Mortensen OH,van Hall G,Moseley PL,Pedersen BK

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Due to resource limitations, few critical care interventions have been rigorously evaluated with adequately powered randomized clinical trials (RCTs). There is a need to improve the efficiency of RCTs in critical care so that more definitive high quality RCTs can be completed with the available resources. ...

journal_title：Critical care (London, England)

authors： Heyland DK,Muscedere J,Drover J,Jiang X,Day AG,Canadian Critical Care Trials Group.

更新日期：2011-01-01 00:00:00