Genome-Wide Scan for Methylation Profiles in Keloids.

abstract：OBJECTIVES:Increases in red blood cell distribution width (RDW) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) predict the mortality of chronic heart failure patients undergoing cardiac resynchronization therapy (CRT). It was hypothesized that RDW is independent of and possibly even superior to NT-proBNP fro...

journal_title：Disease markers

authors： Boros AM,Perge P,Jenei Z,Karády J,Zima E,Molnár L,Becker D,Gellér L,Prohászka Z,Merkely B,Széplaki G

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder that accounts for nearly 70% of the more than 46 million dementia cases estimated worldwide. Although there is no cure for AD, early diagnosis and an accurate characterization of the disease progression can improve the quality of life of AD patients and their ca...

journal_title：Disease markers

authors： Cassani R,Estarellas M,San-Martin R,Fraga FJ,Falk TH

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:Lymph node (LN) metastasis was an independent risk factor for stomach cancer recurrence, and the presence of LN metastasis has great influence on the overall survival of stomach cancer patients. Thus, accurate prediction of the presence of lymph node metastasis can provide guarantee of credible prognosis eva...

journal_title：Disease markers

authors： Wu J,Xiao Y,Xia C,Yang F,Li H,Shao Z,Lin Z,Zhao X

更新日期：2017-01-01 00:00:00

abstract：Background and Objective:Reduced expression of syndecan-1 (CD138), increased proliferation index, and modifications in the expression of the molecular RANK/RANKL/OPG triad are related to an intensified potential of aggressiveness and invasion of diverse tumors and cysts. The aim was to compare the expression of Ki-67, ...

journal_title：Disease markers

authors： Brito-Mendoza L,Bologna-Molina R,Irigoyen-Camacho ME,Martinez G,Sánchez-Romero C,Mosqueda-Taylor A

更新日期：2018-07-29 00:00:00

abstract：Background:Breast cancer is the commonest malignancy in women worldwide. It is estimated to affect approximately 1.5 million women annually and responsible for the greatest number of cancer-related mortalities among women. In 2018, breast cancer mortalities stood at 627,000 women representing approximately 15% of all c...

journal_title：Disease markers

authors： Arko-Boham B,Owusu BA,Aryee NA,Blay RM,Owusu EDA,Tagoe EA,Adams AR,Gyasi RK,Adu-Aryee NA,Mahmood S

更新日期：2020-05-24 00:00:00

abstract：:The human papilloma virus (HPV) associated with hyperplastic epithelium in an oral denture fibroma was examined by southern blot hybridization. Extracted DNA was hybridized with full length linear HPV type 2a, 6b, 11, 16, 18, 31 and 33 DNAs as a mixed probe only under low stringent conditions. The hybridized bands dig...

journal_title：Disease markers

authors： Yamaguchi T,Shindoh M,Amemiya A,Notani K,Fukuda H,Sakaoka H,Inoue M,Fujinaga K

更新日期：1997-04-01 00:00:00

abstract：:The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial infarction (AMI) does not decrease regardless of implementation of new technologies supporting opening culprit coronary artery and solving of ischemia-relating stenosis with primary percutaneous coronary intervention (PCI). Numerous...

journal_title：Disease markers

authors： Berezin AE,Berezin AA

更新日期：2020-06-12 00:00:00

abstract：:A limited number of studies have been performed so far on the polymorphism in the transmembrane region (exon 5) of the major histocompatibility complex class I chain-related gene A (MICA) in patients with melanoma. However, the influence of MICA polymorphism in extracellular domains (exons 2, 3, and 4) has not been in...

journal_title：Disease markers

authors： Campillo JA,López-Hernández R,Martínez-Banaclocha H,Bolarín JM,Gimeno L,Mrowiec A,López M,Las Heras B,Minguela A,Moya-Quiles MR,Legáz I,Frías-Iniesta JF,García-Alonso AM,Álvarez-López MR,Martínez-Escribano JA,Muro M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:To evaluate serum chemerin levels in patients with osteoporosis and healthy controls and to investigate the relationship between serum chemerin levels and bone mineral density (BMD). METHODS:An age- and gender-matched case-control study was conducted. Pearson's correlation test was performed to investigate ...

journal_title：Disease markers

authors： He J,Li JC,Xie H,Xu ZH,Sun YW,Shan Q

更新日期：2015-01-01 00:00:00

abstract：:Epithelial ovarian cancer (EOC) is the sixth most common cause of cancer deaths in women because the diagnosis occurs mostly when the disease is in its late-stage. Current diagnostic methods of EOC show only a moderate sensitivity, especially at an early-stage of the disease; hence, novel biomarkers are needed to impr...

journal_title：Disease markers

authors： Biskup K,Braicu EI,Sehouli J,Tauber R,Blanchard V

更新日期：2014-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a head and neck cancer that is highly found in distinct geographic areas, such as Southeast Asia. The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis. Therefore, it is necessary to fin...

journal_title：Disease markers

authors： Janvilisri T

更新日期：2015-01-01 00:00:00

abstract：:Nevirapine (NVP) is an effective nonnucleoside reverse transcriptase inhibitor (NNRTI) of particular interest as it is often used in resource limited countries. However, one of the main concerns with the use of NVP is hepatotoxicity and elevation of liver enzymes as a consequence of highly active antiretroviral therap...

journal_title：Disease markers

authors： Wongtrakul J,Thongtan T,Roytrakul S,Kumrapich B,Janphen K,Praparattanapan J,Supparatpinyo K,Smith DR

更新日期：2014-01-01 00:00:00

abstract：Aim:To evaluate the diagnosis value of serum human epididymis protein 4 (HE4), cancer antigen 125 (CA125), the Risk of Ovarian Malignancy Algorithm (ROMA), and Copenhagen Index (CPH-I) at early stages for differentiating borderline ovarian tumors from epithelial ovarian cancer. Methods:We recruited 144 borderline ovar...

journal_title：Disease markers

authors： Wang Z,Tao X,Ying C

更新日期：2019-10-13 00:00:00

abstract：INTRODUCTION:Acute gangrenous appendicitis (AGA) is a common medical condition; however, the grade of appendicitis usually cannot be established preoperatively. We have attempted to identify some indicators, such as the mean platelet volume (MPV) and the platelet distribution width (PDW), to diagnose AGA. Aims. To eval...

journal_title：Disease markers

authors： Fan Z,Pan J,Zhang Y,Wang Z,Zhu M,Yang B,Shi L,Jing H

更新日期：2015-01-01 00:00:00

abstract：:The atomic force microscope (AFM) is emerging as a powerful tool in cell biology. Originally developed for high-resolution imaging purposes, the AFM also has unique capabilities as a nano-indenter to probe the dynamic viscoelastic material properties of living cells in culture. In particular, AFM elastography combines...

journal_title：Disease markers

authors： Costa KD

更新日期：2003-01-01 00:00:00

abstract：:Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of vascular disorders such as atherosclerosis and restenosis. And this process has been related to remodeling of L-type calcium channel (LTCC). We attempted to investigate whether fluvastatin has any effect on VSMC proliferation and LTCCα 1...

journal_title：Disease markers

authors： Ouyang QF,Han Y,Lin ZH,Xie H,Xu CS,Xie LD

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less eff...

journal_title：Disease markers

authors： Lopes MP,Santos MN,Faber EW,Bezerra MA,Hatzlhofer BL,Albuquerque DM,Zaccariotto TR,Ribeiro DM,Araújo Ada S,Costa FF,Sonati Mde F

更新日期：2014-01-01 00:00:00

abstract：Aims:The study is aimed at studying the incidence of acute kidney injury (AKI) and exploring the potential predictor for AKI in patients with acute pancreatitis. Methods:A retrospective study adopting a stratified cohort sampling design was performed in a cohort of patients (n = 237) diagnosed with acute pancreatitis ...

journal_title：Disease markers

authors： Chai X,Huang HB,Feng G,Cao YH,Cheng QS,Li SH,He CY,Lu WH,Qin MM

更新日期：2018-11-19 00:00:00

abstract：OBJECTIVES:Elevated humoral responses to cytomegalovirus (CMV) associate with increased risk of cardiovascular disease (CVD) in HIV patients on antiretroviral therapy (ART). To better understand the persistence of CMV humoral responses in relation to CVD, we determined trends in CMV antibody levels over the first 10 ye...

journal_title：Disease markers

authors： Brunt SJ,Lee S,D'Orsogna L,Bundell C,Burrows S,Price P

更新日期：2014-01-01 00:00:00

abstract：:The cell surface glycoprotein KAI1/CD82 suppresses tumor growth and metastasis in animal models. This study aimed to evaluate the prognostic relevance of KAI1/CD82 protein expression in human gastric cancer. Primary gastric carcinomas (n=271) with a mean clinical follow-up time of 48 months were immunostained using th...

journal_title：Disease markers

authors： Knoener M,Krech T,Puls F,Lehmann U,Kreipe H,Christgen M

更新日期：2012-01-01 00:00:00

abstract：:Accumulating evidence suggests that the tumor microenvironment has a profound influence on tumor initiation and progression, opening a new avenue for studying tumor biology. Nonetheless, the prognostic values of the peritumoral expression of EpCAM and CD13 remain to be elucidated in hepatocellular carcinoma (HCC) pati...

journal_title：Disease markers

authors： Dai XM,Huang T,Yang SL,Zheng XM,Chen GG,Zhang T

更新日期：2017-01-01 00:00:00

abstract：Purpose:To investigate the association of galectin-3 (Gal-3) and soluble ST2 (sST2) and their follow-up changes with the development of heart failure (HF) and echocardiographic parameters of HF (ejection fraction, atrial and ventricular size, left ventricular hypertrophy, e', and E/e') in patients with ST-segment eleva...

journal_title：Disease markers

authors： Tymińska A,Kapłon-Cieślicka A,Ozierański K,Budnik M,Wancerz A,Sypień P,Peller M,Balsam P,Opolski G,Filipiak KJ

更新日期：2019-10-10 00:00:00

abstract：Objective:A growing body of emerging evidence indicates that metabolic processes play a pivotal role in the biological processes underlying acute myocardial infarction (AMI). The aim of the current study was to identify featured metabolism-related genes in patients with AMI using a support vector machine (SVM) and to f...

journal_title：Disease markers

authors： Xie H,Zha E,Zhang Y

更新日期：2020-11-28 00:00:00

abstract：OBJECTIVE:Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in p...

journal_title：Disease markers

authors： Zhu ZL,Yan BY,Zhang Y,Yang YH,Wang ZM,Zhang HZ,Wang MW,Zhang XH,Sun XF

更新日期：2012-01-01 00:00:00

abstract：:A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor o...

journal_title：Disease markers

authors： Chatterjee A,Rathore A,Vidyant S,Kakkar K,Dhole TN

更新日期：2012-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2138627.]. ...

journal_title：Disease markers

authors： Marrugal Á,Ojeda L,Paz-Ares L,Molina-Pinelo S,Ferrer I

更新日期：2018-07-08 00:00:00

abstract：BACKGROUND:The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk. Although many studies have demonstrated the importance of the apoB/apoA-I ratio in predicting t...

journal_title：Disease markers

authors： Kaneva AM,Potolitsyna NN,Bojko ER,Odland JØ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Tumor cells show alterations in their glycosylation patterns when compared to normal cells. Lectins can be used to evaluate these glycocode changes. Chemiluminescence assay is an effective technique for quantitative analysis of proteins, nucleic acids, and carbohydrates due to its high sensitivity, specifici...

journal_title：Disease markers

authors： Lima LR,Bezerra MF,Almeida SM,Silva LP,Beltrão EI,Carvalho Júnior LB

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system. DESIGN:...

journal_title：Disease markers

authors： Nasti S,Spallarossa P,Altieri P,Garibaldi S,Fabbi P,Polito L,Bacino L,Brunelli M,Brunelli C,Barsotti A,Ghigliotti G

更新日期：2006-01-01 00:00:00

abstract：:This study evaluated the in vitro sensitivity of paired Leishmania braziliensis samples isolated from the same patient before pentavalent antimonial treatment (Sample A) and after treatment failure or cutaneous leishmaniasis reactivation (Sample B) in patients undergoing intralesional administration or injections (5 m...

journal_title：Disease markers

authors： Baptista C,Miranda Lde F,Madeira Mde F,Leon LL,Conceição-Silva F,Schubach Ade O

更新日期：2015-01-01 00:00:00