Regional Quantitative Magnetic Resonance Imaging Data Improve Screening Accuracy of Subjective Memory Complaints and Informant Reports of Cognitive Decline.

Abstract:

OBJECTIVE:We investigated whether the addition of Alzheimer's disease-signature region cortical thickness (AD-Ct) and hippocampal volume (Hv) obtained from brain MRI to subjective memory complaints and informant-reports of cognitive decline enhances the screening accuracy for cognitive disorders in a memory clinic setting. METHODS:120 participants (40 cognitively normal, 40 MCI, 40 dementia) underwent clinical evaluation, neuropsychological assessment, and brain MRI. The Subjective Memory Complaints Questionnaire (SMCQ) and Seoul Informant-Report Questionnaire for Dementia (SIRQD) were applied to assess subjective memory complaints and informant-reports of cognitive decline respectively. Logistic regression and ROC curve analyses were conducted to compare the screening abilities of SMCQ+SIRQD, SMCQ+SIRQD+Hv, and SMCQ+SIRQD+AD-Ct models for cognitive disorders. RESULTS:SMCQ+SIRQD+Hv model indicated better screening accuracy for MCI and overall cognitive disorder (CDall) than SMCQ+ SIRQD model. SMCQ+SIRQD+AD-Ct model had superior screening accuracy for dementia in comparison to SMCQ+SIRQD model. ROC curve analyses revealed that SMCQ+SIRQD+Hv model had the greatest area under the curve (AUC) for screening MCI and CDall (AUC: 0.941 and 0.957), while SMCQ+SIRQD+AD-Ct model had the greatest AUC for screening dementia (AUC: 0.966). CONCLUSION:Our results suggest that the addition of regional quantitative MRI data enhances the screening ability of subjective memory complaints and informant-reports of cognitive decline for MCI and dementia.

journal_name

Psychiatry Investig

journal_title

Psychiatry investigation

authors

Yim SJ,Yi D,Byun MS,Sung K,Lee DY

doi

10.30773/pi.2020.0323

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

851-857

issue

9

eissn

1738-3684

issn

1976-3026

pii

pi.2020.0323

journal_volume

17

pub_type

杂志文章
  • Differences in Performance of ADHD Children on a Visual and Auditory Continuous Performance Test according to IQ.

    abstract:OBJECTIVE:Continuous performance tests (CPTs) are frequently used in clinical practice to assess the attentiveness of ADHD children. Although most CPTs do not categorize T scores by intelligence, there is great diversity of opinion regarding the interrelation between intelligence and CPT performance. This study aimed t...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2011.8.3.227

    authors: Park MH,Kweon YS,Lee SJ,Park EJ,Lee C,Lee CU

    更新日期:2011-09-01 00:00:00

  • New-onset mania following bariatric surgery.

    abstract::Obesity has become a major public health problem over the past two decades. Non-surgical management of obesity does not often achieve its long term goals. Surgical treatment is roaring in popularity because of dramatic and durable results. However, outcomes from bariatric surgery have become a significant area of scru...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.1.152

    authors: Nepal H,Bhattarai M,Agustin ET

    更新日期:2015-01-01 00:00:00

  • Desensitization of Triggers and Urge Reduction for Paruresis: A Case Report.

    abstract::Paruresis is a special type of non-generalized social phobia that involves fear and avoidance of urination in public restrooms. We administered eight 60-minute sessions of desensitization of triggers and urge reduction (DeTUR), an addiction protocol of eye movement desensitization and reprocessing (EMDR) therapy, to a...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2016.13.1.161

    authors: Park H,Kim D,Jang EY,Bae H

    更新日期:2016-01-01 00:00:00

  • Reliability and Validity of the Korean Version of Somatic Symptom Scale-8.

    abstract:OBJECTIVE:Somatic symptoms in psychiatry include underlying depression, anxiety, or other psychiatric disorders. This study aimed to conduct a validation study of a Korean version of the Somatic Symptom Scale-8 (K-SSS-8), and to utilize the K-SSS-8 effectively in clinical settings. METHODS:For reliabilty, test-retest ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2020.0112

    authors: Yang CM,Hwang KS,Lee SY,Seo JS,Jang SH

    更新日期:2020-08-01 00:00:00

  • Generalized anxiety disorder, comorbid major depression and heart rate variability: a case-control study in taiwan.

    abstract:OBJECTIVE:Decreased heart rate variability (HRV) has been reported in generalized anxiety disorder (GAD), but the results are mixed. Little is known about the impact of comorbid major depression (MD) on HRV in GAD patients. Both issues necessitate further investigation. METHODS:Twenty unmedicated, physically healthy G...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.4.326

    authors: Chang HA,Chang CC,Tzeng NS,Kuo TB,Lu RB,Huang SY

    更新日期:2013-12-01 00:00:00

  • Factors Associated with Complicated Grief in Students Who Survived the Sewol Ferry Disaster in South Korea.

    abstract:OBJECTIVE:The Sewol ferry disaster caused shock and grief in South Korea. The aim of this study was to identify the factors associated with symptoms of complicated grief (CG) among the surviving students 20 months after that disaster. METHODS:This study was conducted using a cross-sectional design and a sample of 57 s...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2017.05.04

    authors: Lee SH,Nam HS,Kim HB,Kim EJ,Noh JW,Chae JH

    更新日期:2018-03-01 00:00:00

  • The Effects of 5-HTR1A Polymorphism on Cingulum Connectivity in Patients with Panic Disorder.

    abstract:OBJECTIVE:Serotonin-1A receptors (5-HTR1A) is suggested to be involved in the etiology of several psychiatric disorders including panic disorder (PD). A few imaging studies have suggested the alterations of the cingulum bundle in PD. The objective of this study is to examine the structural changes of cingulum related t...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.4.399

    authors: Yu ST,Kim MK,Kim B,Yoo E,Lee JY,Lee KS,Choe AY,Yook KH,Choi TK,Lee SH

    更新日期:2013-12-01 00:00:00

  • Disruption of orbitofronto-striatal functional connectivity underlies maladaptive persistent behaviors in alcohol-dependent patients.

    abstract:OBJECTIVE:Alcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit. METHODS:Twenty one alcohol dependent patients an...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.3.266

    authors: Lee S,Lee E,Ku J,Yoon KJ,Namkoong K,Jung YC

    更新日期:2013-09-01 00:00:00

  • The Association between Depressive Mood and Cholesterol Levels in Korean Adolescents.

    abstract:OBJECTIVE:Previous studies have shown that there is a correlation between lipid levels and depressive mood, and that lipids could be useful biomarkers for depression. We conducted this study to clarify the association between lipid levels and depressive mood in adolescents, especially in community samples. METHODS:We ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.03.24

    authors: Kim EJ,Hong J,Hwang JW

    更新日期:2019-10-01 00:00:00

  • Functional Connectivity of the Striatum as a Neural Correlate of Symptom Severity in Patient with Obsessive-Compulsive Disorder.

    abstract:OBJECTIVE:It is well established that the cortico-striato-thalamo-cortical (CSTC) circuit is implicated in the pathophysiology of obsessive- compulsive disorder (OCD). However, reports on corticostriatal functional connectivity (FC) in OCD have been inconsistent due to the structural and functional heterogeneity of the...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0206

    authors: Park J,Kim T,Kim M,Lee TY,Kwon JS

    更新日期:2020-02-01 00:00:00

  • Modulation of Electrophysiology by Transcranial Direct Current Stimulation in Psychiatric Disorders: A Systematic Review.

    abstract:OBJECTIVE:Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique increasingly used to relieve symptoms of psychiatric disorders. Electrophysiologic markers, such as electroencephalography (EEG) and event-related potentials (ERP), have high temporal resolution sensitive to detect plas...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2018.01.10

    authors: Kim M,Kwak YB,Lee TY,Kwon JS

    更新日期:2018-05-01 00:00:00

  • Clinical, Psychopathological, Physical, and Sleep Evolution in Adolescents with Restrictive Anorexia Nervosa Participating in a Day Hospital Program.

    abstract:OBJECTIVE:To analyze the clinical, psychopathological, physical, and sleep-related evolution of adolescents with restricting-type of anorexia nervosa (AN-R) after 10 weeks of a daytime hospital program. METHODS:Body composition, physical activity and sleep were measured objectively before and after 10 weeks of treatme...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2020.0016

    authors: Martínez-Sánchez SM,Martínez-García TE,Munguía-Izquierdo D

    更新日期:2020-04-01 00:00:00

  • Distinguishing Quantitative Electroencephalogram Findings between Adjustment Disorder and Major Depressive Disorder.

    abstract:OBJECTIVE:Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.1.62

    authors: Jeong HG,Ko YH,Han C,Kim YK,Joe SH

    更新日期:2013-03-01 00:00:00

  • Relationship between Delusion of Theft and Cognitive Functions in Patients with Mild Alzheimer's Disease.

    abstract::Although delusion of theft (DT) is the most frequent type of delusion in Alzheimer's disease (AD), its relationship to cognitive functions remains unclear. The aim of this study was to demonstrate the relationship between DT and cognitive functions in mild AD. Two hundred eighty-nine mild AD patients were enrolled in ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2017.09.20

    authors: Na HR,Kang DW,Woo YS,Bahk WM,Lee CU,Lim HK

    更新日期:2018-04-01 00:00:00

  • The Economic Crisis in Greece and Its Impact on the Seasonality of Suicides in the Athens Greater Area.

    abstract:OBJECTIVE:The economic crisis and the implementation of austerity measures in Greece lead to significant socioeconomic changes. The effects of the crisis were mainly felt by the Greek population during the years 2011 and 2012. This study aimed to investigate the impact of Greece's economic crisis on the seasonality of ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.1.16

    authors: Christodoulou C,Efstathiou V,Michopoulos I,Gkerekou M,Paraschakis A,Koutsaftis F,Douzenis A

    更新日期:2017-01-01 00:00:00

  • Stigma of mental illnesses as perceived by north korean defectors living in South Korea.

    abstract:OBJECTIVE:This study aims to provide the information of the stigmas of mental illness such as psychosis, alcoholism, attempt suicide, and depression among North Korean defectors. METHODS:We examined stigma for the mental illnesses of 639 North Korean defectors aged 19 to 65 years who live in the Settlement Support Cen...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.1.9

    authors: Ahn JH,Kim WH,Choi HJ,Jeon JY,Song IG,Bae JN

    更新日期:2015-01-01 00:00:00

  • Are Mentalizing Abilities and Insight Related to the Severity of Obsessive-Compulsive Disorder.

    abstract:OBJECTIVE:The aim of this study is to investigate whether insight and mentalizing abilities are related to the severity of Obsessive Compulsive Disorder (OCD) in treatment resistant OCD. We look at the association between treatment resistance, insight, and mentalizing ability. METHODS:The study was conducted with 71 O...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2018.05.02.2

    authors: İnanç L,Altıntaş M

    更新日期:2018-09-01 00:00:00

  • Psychometric Properties of the Self-Report Version of the Strengths and Difficulties Questionnaire in Korea.

    abstract:OBJECTIVE:To examine the reliability and validity of the self-report Korean version of Strengths and Difficulties Questionnaire (SDQ-Kr) in the community sample. METHODS:The SDQ-Kr was administered to a large sample of school children and adolescents (n=2814) and youth attendees of a psychiatric clinic (n=385) aged 11...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.4.491

    authors: Kim MH,Ahn JS,Min S

    更新日期:2015-10-01 00:00:00

  • Validation of the Korean Version of the Delirium Motor Subtype Scale.

    abstract:Objective:The Delirium Motor Subtype Scale (DMSS) is a validated and reliable instrument developed from various methods previously used to assess delirium motor subtypes. It focuses on pure motor disturbances with a relative specificity for delirium. The aim of this study was to investigate the validity and reliability...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2018.15.1.6

    authors: Kim H,Lee M,Kwon IS,Kim JL

    更新日期:2018-01-01 00:00:00

  • Development of a Biomarker-Based Diagnostic Algorithm for Posttraumatic Syndrome after Physical Injury: Design of the BioPTS Study.

    abstract::Severe physical injury is a leading cause of posttraumatic syndrome (PTS). This is to develop a biomarker-based diagnostic algorithm for posttraumatic syndrome (BioPTS) study. This is a 2-year longitudinal cohort study assessing patients who were hospitalized beginning in 2015 at Chonnam National University Hospital i...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.4.513

    authors: Kim JW,Kang HJ,Bae KY,Kim SW,Oh HK,Kim MG,Kim JM

    更新日期:2017-07-01 00:00:00

  • Evaluation of Oxidative Metabolism in Child and Adolescent Patients with Attention Deficit Hyperactivity Disorder.

    abstract:OBJECTIVE:Oxidative metabolism is impaired in several medical conditions including psychiatric disorders, and this imbalance may be involved in the etiology of these diseases. The present study evaluated oxidative balance in pediatric and adolescent patients with attention deficit hyperactivity disorder (ADHD). METHOD...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.3.361

    authors: Kul M,Unal F,Kandemir H,Sarkarati B,Kilinc K,Kandemir SB

    更新日期:2015-07-01 00:00:00

  • Prolonged Drug-Drug Interaction between Terbinafine and Perphenazine.

    abstract::I report here an elderly woman receiving perphenazine together with terbinafine. After 1 week of terbinafine treatment she experienced extrapyramidal symptoms and, in particular, akathisia. Her symptoms did not disappear for 6 weeks, and so at 2 weeks prior to this most recent admission she had stopped taking terbinaf...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2012.9.4.422

    authors: Park YM

    更新日期:2012-12-01 00:00:00

  • Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder.

    abstract:OBJECTIVE:The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BP-BL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors. METHODS:Among 67 patients who received ECT and diagnosed with schizophrenia/sch...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.06.20.2

    authors: Jeong SH,Youn T,Lee Y,Jang JH,Jeong YW,Kim YS,Chung IW

    更新日期:2019-09-01 00:00:00

  • Two cases of hypersexuality probably associated with aripiprazole.

    abstract::Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desi...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.2.200

    authors: Cheon E,Koo BH,Seo SS,Lee JY

    更新日期:2013-06-01 00:00:00

  • Neural Mechanism of Inferring Person's Inner Attitude towards Another Person through Observing the Facial Affect in an Emotional Context.

    abstract:OBJECTIVE:The goal of the present study was to identify the brain mechanism involved in the attribution of person's attitude toward another person, using facial affective pictures and pictures displaying an affectively-loaded situation. METHODS:Twenty four right-handed healthy subjects volunteered for our study. We us...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2010.7.1.31

    authors: Kim JW,Kim JJ,Jeong B,Kim SE,Ki SW

    更新日期:2010-03-01 00:00:00

  • Linking an Anxiety-Related Personality Trait to Cardiac Autonomic Regulation in Well-Defined Healthy Adults: Harm Avoidance and Resting Heart Rate Variability.

    abstract:OBJECTIVE:Anxiety trait, anxiety and depression states have all been reported to increase risks for cardiovascular disease (CVD), possibly through altering cardiac autonomic regulation. Our aim was to investigate whether the relationship between harm avoidance (HA, an anxiety-related personality trait) and cardiac auto...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2016.13.4.397

    authors: Kao LC,Liu YW,Tzeng NS,Kuo TB,Huang SY,Chang CC,Chang HA

    更新日期:2016-07-01 00:00:00

  • Avoidant Insecure Attachment as a Predictive Factor for Psychological Distress in Patients with Early Breast Cancer: A Preliminary 1-Year Follow-Up Study.

    abstract: Objective:To identify attachment insecurity as an associative factor with unresolved psychological distress 1 year after surgery in the early breast cancer (BC) population. Methods:One-hundred fourteen participants completed the Hospital Anxiety and Depression Scale (HADS) and the Experiences in Close Relationship (E...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2018.06.07

    authors: Lee SS,Rim HD,Won SH,Woo J

    更新日期:2018-08-01 00:00:00

  • Age-Related Changes in Auditory Nogo-N200 Latency in Medication-Naïve Children and Adolescents with Attention-Deficit/Hyperactivity Disorder.

    abstract:OBJECTIVE:Event-related potential (ERP) changes with brain development in healthy children and adolescents. However, few studies have focused on age-related changes in the N200 and P300 components among individuals with attention-deficit/hyperactivity disorder (ADHD). Therefore, this study aimed to assess age-related d...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2020.0083

    authors: Lee YJ,Jeong MY,Park S,Kim JH,Kim JS,Woo SI

    更新日期:2020-07-01 00:00:00

  • Fluoxetine increases the expression of NCAM140 and pCREB in rat C6 glioma cells.

    abstract:OBJECTIVE:Dysfunction of neural plasticity in the brain is known to alter neural networks, resulting in depression. To understand how fluoxetine regulates molecules involved in neural plasticity, the expression levels of NCAM, NCAM140, CREB and pCREB, in rat C6 glioma cells after fluoxetine treatment were examined. ME...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2012.9.2.180

    authors: Choi MR,Oh DH,Kim SH,Jung KH,Das ND,Chai YG

    更新日期:2012-06-01 00:00:00

  • Anger-Related Characteristics According to Chronotypes in Bipolar or Depressive Disorders.

    abstract:OBJECTIVE:Though anger was highly associated with eveningness in general population, there is no study on the relationship between chronotype and anger-related characteristics in bipolar or depressive disorders. This study aimed to investigate the difference of anger-related characteristics according to chronotypes in ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0326

    authors: Kang TU,Moon E,Choi Y,Suh H,Park JM,Lee BD,Lee YM,Jeong HJ,Kim SY,Lee K,Lim HJ,Yoon M

    更新日期:2020-09-01 00:00:00