Abstract:
OBJECTIVE:We investigated whether the addition of Alzheimer's disease-signature region cortical thickness (AD-Ct) and hippocampal volume (Hv) obtained from brain MRI to subjective memory complaints and informant-reports of cognitive decline enhances the screening accuracy for cognitive disorders in a memory clinic setting. METHODS:120 participants (40 cognitively normal, 40 MCI, 40 dementia) underwent clinical evaluation, neuropsychological assessment, and brain MRI. The Subjective Memory Complaints Questionnaire (SMCQ) and Seoul Informant-Report Questionnaire for Dementia (SIRQD) were applied to assess subjective memory complaints and informant-reports of cognitive decline respectively. Logistic regression and ROC curve analyses were conducted to compare the screening abilities of SMCQ+SIRQD, SMCQ+SIRQD+Hv, and SMCQ+SIRQD+AD-Ct models for cognitive disorders. RESULTS:SMCQ+SIRQD+Hv model indicated better screening accuracy for MCI and overall cognitive disorder (CDall) than SMCQ+ SIRQD model. SMCQ+SIRQD+AD-Ct model had superior screening accuracy for dementia in comparison to SMCQ+SIRQD model. ROC curve analyses revealed that SMCQ+SIRQD+Hv model had the greatest area under the curve (AUC) for screening MCI and CDall (AUC: 0.941 and 0.957), while SMCQ+SIRQD+AD-Ct model had the greatest AUC for screening dementia (AUC: 0.966). CONCLUSION:Our results suggest that the addition of regional quantitative MRI data enhances the screening ability of subjective memory complaints and informant-reports of cognitive decline for MCI and dementia.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Yim SJ,Yi D,Byun MS,Sung K,Lee DYdoi
10.30773/pi.2020.0323subject
Has Abstractpub_date
2020-09-01 00:00:00pages
851-857issue
9eissn
1738-3684issn
1976-3026pii
pi.2020.0323journal_volume
17pub_type
杂志文章abstract:OBJECTIVE:Continuous performance tests (CPTs) are frequently used in clinical practice to assess the attentiveness of ADHD children. Although most CPTs do not categorize T scores by intelligence, there is great diversity of opinion regarding the interrelation between intelligence and CPT performance. This study aimed t...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2011.8.3.227
更新日期:2011-09-01 00:00:00
abstract::Obesity has become a major public health problem over the past two decades. Non-surgical management of obesity does not often achieve its long term goals. Surgical treatment is roaring in popularity because of dramatic and durable results. However, outcomes from bariatric surgery have become a significant area of scru...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.1.152
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journal_title:Psychiatry investigation
pub_type: 杂志文章
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2020.0112
更新日期:2020-08-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.4.326
更新日期:2013-12-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2017.05.04
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.4.399
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.3.266
更新日期:2013-09-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.03.24
更新日期:2019-10-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.01.10
更新日期:2018-05-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2020.0016
更新日期:2020-04-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.1.62
更新日期:2013-03-01 00:00:00
abstract::Although delusion of theft (DT) is the most frequent type of delusion in Alzheimer's disease (AD), its relationship to cognitive functions remains unclear. The aim of this study was to demonstrate the relationship between DT and cognitive functions in mild AD. Two hundred eighty-nine mild AD patients were enrolled in ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2017.09.20
更新日期:2018-04-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.1.16
更新日期:2017-01-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.1.9
更新日期:2015-01-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.05.02.2
更新日期:2018-09-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.4.491
更新日期:2015-10-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2018.15.1.6
更新日期:2018-01-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.4.513
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.3.361
更新日期:2015-07-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.4.422
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.06.20.2
更新日期:2019-09-01 00:00:00
abstract::Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desi...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.2.200
更新日期:2013-06-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2010.7.1.31
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Anxiety trait, anxiety and depression states have all been reported to increase risks for cardiovascular disease (CVD), possibly through altering cardiac autonomic regulation. Our aim was to investigate whether the relationship between harm avoidance (HA, an anxiety-related personality trait) and cardiac auto...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.4.397
更新日期:2016-07-01 00:00:00
abstract: Objective:To identify attachment insecurity as an associative factor with unresolved psychological distress 1 year after surgery in the early breast cancer (BC) population. Methods:One-hundred fourteen participants completed the Hospital Anxiety and Depression Scale (HADS) and the Experiences in Close Relationship (E...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.06.07
更新日期:2018-08-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.2.180
更新日期:2012-06-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0326
更新日期:2020-09-01 00:00:00