Relationship between Delusion of Theft and Cognitive Functions in Patients with Mild Alzheimer's Disease.

Abstract:

:Although delusion of theft (DT) is the most frequent type of delusion in Alzheimer's disease (AD), its relationship to cognitive functions remains unclear. The aim of this study was to demonstrate the relationship between DT and cognitive functions in mild AD. Two hundred eighty-nine mild AD patients were enrolled in this study. These subjects were classified into three groups: patients with no delusions (ND, n=82), patients with paranoid delusions (PD, n=114) and patients with DT (n=93). Cognitive functions and their associations with the degree of delusion were compared among the three groups. The results showed that verbal Fluency scores were significantly lower in the PD group than in the DT and ND groups. Word List Recall scores were significantly lower in the DT group than in the PD and ND groups. Interestingly, delusion severity measured with the Neuropsychiatric Inventory delusion subscale correlated negatively with the Word List Recall scores in the DT group. In this study, we demonstrated that episodic memory functions in mild AD patients were associated with DT, but not with PD. Further studies might be needed to clarify the pathophysiology of delusions associated with AD.

journal_name

Psychiatry Investig

journal_title

Psychiatry investigation

authors

Na HR,Kang DW,Woo YS,Bahk WM,Lee CU,Lim HK

doi

10.30773/pi.2017.09.20

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

413-416

issue

4

eissn

1738-3684

issn

1976-3026

pii

pi-2017-09-20

journal_volume

15

pub_type

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