Abstract:
OBJECTIVE:Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis of an electroencephalogram (QEEG). METHODS:The study included 30 patients with ADJ and 51 patients with MDD. Resting (eye closed) vigilance controlled EEG recordings were assessed at 19 electrode sites according to the international 10/20 system. QEEG absolute power and coherence were calculated for the delta, theta, alpha and beta bandwidths. RESULTS:Absolute powers of alpha and high beta bands, particularly at the frontocentral area, differed between MDD and ADJ group (p<0.05). Interhemispheric coherence values for the delta and beta bands were lower in the ADJ group than in the MDD group (p<0.05). Intrahemispheric coherence values for the alpha band were also lower in the ADJ group (p<0.05). CONCLUSION:The differences in QEEG power and coherence in our investigation suggest that underlying pathophysiologic mechanisms may be different between ADJ and MDD.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Jeong HG,Ko YH,Han C,Kim YK,Joe SHdoi
10.4306/pi.2013.10.1.62subject
Has Abstractpub_date
2013-03-01 00:00:00pages
62-8issue
1eissn
1738-3684issn
1976-3026journal_volume
10pub_type
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