Abstract:
OBJECTIVE:Caregivers for patients with Alzheimer's disease (AD) suffer from psychological and financial burdens. However, the results of the relationship between burden and cognitive function, performance of activities of daily living, and depressive symptoms have remained inconsistent. Therefore, the aim of this study was to examine which factors are more significant predictors of heightened burden, cognitive impairment or functional decline, besides neuropsychiatric symptoms. METHODS:A cross-sectional study was conducted in a sample comprised of 1,164 pairs of patients with AD and caregivers from the Clinical Research of Dementia of South Korea study cohorts. The cognitive function of each sub-domain, functional impairments, depressive symptoms, and caregiver burden were assessed using the dementia version of Seoul Neuropsychological Screening Battery (SNSB-D), Barthel Index for Daily Living Activities (ADL), Seoul-Instrumental Activities of Daily Living (S-IADL), the Clinical Dementia Rating Sum of Box (CDR-SB), the Global Deterioration Scale (GDS), the Korean version of the Neuropsychiatric Inventory (K-NPI), and the 15-item Geriatric Depression Scale. RESULTS:We found that higher severity (higher CDR-SB and GDS scores) and more functional impairment (lower ADL and higher S-IADL scores) were significantly associated with higher caregiver burden. In addition, depressive symptoms of patients (higher Geriatric Depression Scale scores) were associated with higher caregiver burden. CONCLUSION:Therefore, interventions to help maintain activities of daily living in patients with AD may alleviate caregiver burden and improve caregiver well-being.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Kang HS,Myung W,Na DL,Kim SY,Lee JH,Han SH,Choi SH,Kim S,Kim S,Kim DKdoi
10.4306/pi.2014.11.2.152subject
Has Abstractpub_date
2014-04-01 00:00:00pages
152-9issue
2eissn
1738-3684issn
1976-3026journal_volume
11pub_type
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.5.647
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:It is well established that the cortico-striato-thalamo-cortical (CSTC) circuit is implicated in the pathophysiology of obsessive- compulsive disorder (OCD). However, reports on corticostriatal functional connectivity (FC) in OCD have been inconsistent due to the structural and functional heterogeneity of the...
journal_title:Psychiatry investigation
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2017.08.23
更新日期:2018-03-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.3.223
更新日期:2012-09-01 00:00:00
abstract::Drug-assisted interviews are useful for psychiatric diagnosis and treatment. However, amobarbital, a typical medication used for this purpose, is associated with elevated risk of respiratory depression. Benzodiazepines are good substitutes for amobarbital, with similar therapeutic effects and fewer complications. Alth...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2011.8.4.377
更新日期:2011-12-01 00:00:00
abstract::Paruresis is a special type of non-generalized social phobia that involves fear and avoidance of urination in public restrooms. We administered eight 60-minute sessions of desensitization of triggers and urge reduction (DeTUR), an addiction protocol of eye movement desensitization and reprocessing (EMDR) therapy, to a...
journal_title:Psychiatry investigation
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doi:10.4306/pi.2016.13.1.161
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to explore the prognostic values of biomarkers of neurodegeneration as measured by magnetic resonance imaging (MRI) and amyloid burden as measured by amyloid positron emission tomography (PET) in predicting conversion to Alzheimer's disease (AD) in patients with mild cognitive impair...
journal_title:Psychiatry investigation
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doi:10.4306/pi.2017.14.2.205
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:The Life Events Checklist is a brief screening instrument that is used for potentially traumatic events such as accidents, disasters, sexual or physical assaults, or combat-related exposures. The original English version was recently tested for reliability and validity and it showed good psychometric properti...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.3.163
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:Suicide is a leading cause of death in college age students. Identification of the associated risk factors has important implications for how to prevent and respond to this population; however, few studies have been performed on this topic in this age group. The purpose of this study was to evaluate the preva...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.2.86
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to determine the dose-response relationship between physical activity and anxiety symptoms. METHODS:We included data of 124,434 participants who had comprehensive health-screening examinations from January 1st, 2012, to December 31st, 2016, in Kangbuk Samsung Hospital, Seoul and Suwo...
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更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:The Revised Obsessive Intrusion Inventory (ROII) is a 52-item scale that evaluates obsessional intrusive thoughts. The aim of the present study was to validate a short, 20-item Korean version of the ROII (ROII-20). METHODS:Of the 1125 participants who completed the ROII-20, 895 participants completed the sca...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.3.288
更新日期:2015-07-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.1.26
更新日期:2009-03-01 00:00:00
abstract::Hallervorden-Spatz disease (HSD) is a rare autosomal-recessive hereditary disorder characterized by the early onset of progressive movement alterations, including dystonia, rigidity, choreoathetosis, and mental deterioration. HSD is also associated with a variety of psychiatric symptoms, primarily depression and menta...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.3.226
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors (SSRIs) or mirtazipine. METHODS:Nine middle-aged men with major depressive disorder treated with an SSRI and ten middle-aged men w...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.2.85
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters. METHODS:From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2011.8.4.312
更新日期:2011-12-01 00:00:00
abstract::Obesity has become a major public health problem over the past two decades. Non-surgical management of obesity does not often achieve its long term goals. Surgical treatment is roaring in popularity because of dramatic and durable results. However, outcomes from bariatric surgery have become a significant area of scru...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.1.152
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Though anger was highly associated with eveningness in general population, there is no study on the relationship between chronotype and anger-related characteristics in bipolar or depressive disorders. This study aimed to investigate the difference of anger-related characteristics according to chronotypes in ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0326
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Although specific temperaments have been known to be related to autonomic nervous function in some psychiatric disorders, there are few studies that have examined the relationship between temperaments and autonomic nervous function in a normal population. In this study, we examined the effect of temperament o...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.3.293
更新日期:2012-09-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.01.10
更新日期:2018-05-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2010.7.4.264
更新日期:2010-12-01 00:00:00
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journal_title:Psychiatry investigation
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doi:10.30773/pi.2019.02.14
更新日期:2019-05-01 00:00:00
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doi:10.4306/pi.2010.7.3.208
更新日期:2010-09-01 00:00:00
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journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.4.213
更新日期:2008-12-01 00:00:00
abstract::The REAP-AP study recruited 3,746 patients with schizophrenia, in March and April 2016, from 71 centers in 15 Asian countries/territories namely Bangladesh, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Myanmar, Pakistan, Singapore, Sri Lanka, Taiwan, Thailand and Vietnam. Our findings reveal a trend acc...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.09.06
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to investigate whether insight and mentalizing abilities are related to the severity of Obsessive Compulsive Disorder (OCD) in treatment resistant OCD. We look at the association between treatment resistance, insight, and mentalizing ability. METHODS:The study was conducted with 71 O...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.05.02.2
更新日期:2018-09-01 00:00:00
abstract:Objective:The anti-epileptogenic drug levetiracetam has anticonvulsant and anti-epileptogenesis effects. Synergy between cell death and inflammation can lead to increased levels of apoptosis inhibitory factors and brain-derived neurotrophic factor, aberrant neurogenesis and extended axon sprouting. Once hyperexcitation...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.6.844
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the characteristics of psychological factors that are related to irritable bowel syndrome (IBS) and their effects on the quality of life (QOL) of firefighters in South Korea. METHODS:This study examined data collected from 1217 firefighters in South Korea. After i...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.4.434
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that negatively affects different areas of life. We aimed to evaluate the associations between the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) and ADHD and to assess the effect of the BDNF polymorphism on th...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.5.518
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To examine the reliability and validity of the self-report Korean version of Strengths and Difficulties Questionnaire (SDQ-Kr) in the community sample. METHODS:The SDQ-Kr was administered to a large sample of school children and adolescents (n=2814) and youth attendees of a psychiatric clinic (n=385) aged 11...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.4.491
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The purpose of the present study was to clarify the relationship between white matter tracts and cognitive symptoms in children with high-functioning autism spectrum disorder (ASD). METHODS:We examined the cognitive functions of 17 children with high-functioning ASD and 18 typically developing (TD) controls ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.01.16
更新日期:2019-03-01 00:00:00