Two cases of hypersexuality probably associated with aripiprazole.

Abstract:

:Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desire and greater sexual preoccupation after taking aripiprazole. We discuss the potential neuro-chemical mechanisms for this and argue that aripiprazole's unique pharmacological profile, partial agonism with high affinity at dopamine D2-receptor, may have contributed to the development of these symptoms.

journal_name

Psychiatry Investig

journal_title

Psychiatry investigation

authors

Cheon E,Koo BH,Seo SS,Lee JY

doi

10.4306/pi.2013.10.2.200

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

200-2

issue

2

eissn

1738-3684

issn

1976-3026

journal_volume

10

pub_type

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