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Function of respiratory system evaluated using selected spirometry parameters in persons occupationally exposed to lead without evident health problems.

Abstract：

UNLABELLED:This study aimed at evaluation of selected spirometric parameters in persons occupationally exposed to lead without evident health problems. The studies were conducted on 69 men occupationally exposed to lead. Occupational exposure to lead was characterized by estimation of blood lead concentration (Pb-B) and blood zinc protoporphyrin concentration (ZnPP). Function of respiratory system was examined using spirometric analysis with evaluation of its basic parameters: forced vital capacity (FVC), forced expiratory volume (in 1s) (FEV1), Tiffeneau index (FEV1%VC) and peak expiratory flow (PEF). In the study group negative linear correlations were documented between Pb-B and FVC, FEV 1 and FEV1%VC. A more pronounced age, higher values of BMI and higher blood lead concentration constituted independent risk factors for reduced FEV1%VC. CONCLUSION:Persons occupationally exposed to lead with elevated blood lead concentration and blood zinc protoporphyrin concentration manifested the impaired function of respiratory system, evaluated using parameters of spirometry.

journal_name

Environ Toxicol Pharmacol

journal_title

Environmental toxicology and pharmacology

authors

Jurdziak M,Gać P,Martynowicz H,Poręba R

doi

10.1016/j.etap.2015.03.009

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

1034-40

issue

3

eissn

1382-6689

issn

1872-7077

pii

S1382-6689(15)00073-3

journal_volume

39

pub_type

杂志文章

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