Hydroxyethylstarch revisited for acute brain injury treatment.

abstract：:The present study involved a questionnaire survey of 156 mothers that gave birth to children with neural tube defects or had a history of pregnancy resulting in children with neural tube defects (case group) and 156 control mothers with concurrent healthy children (control group) as well as detection of mitochondrial ...

journal_title：Neural regeneration research

authors： Liu Z,Xie J,Luo T,Zhang T,Zhao X,Zhao H,Li P

更新日期：2012-02-25 00:00:00

abstract：:A mixture of ibotenic acid and β-amyloid 1-42 was injected into the hippocampus of a rat model of Alzheimer's disease, followed by intragastric administration of a traditional Chinese medicine Buyuan Congnao decoction (main components included radix astragali, radix polygoni multiflori preparata, rhizoma acori talarin...

journal_title：Neural regeneration research

authors： Chen M,Wang J,Ming C

更新日期：2012-03-25 00:00:00

abstract：:Clinical studies have shown that hyperbaric oxygen therapy improves motor function in patients with spinal cord injury. In the present study, we explored the mechanisms associated with the recovery of neurological function after hyperbaric oxygen therapy in a rat model of spinal cord injury. We established an acute sp...

journal_title：Neural regeneration research

authors： Wang Y,Zhang S,Luo M,Li Y

更新日期：2014-12-15 00:00:00

abstract：:Cerebral ischemia triggers secondary ischemia/reperfusion injury and endoplasmic reticulum stress initiates cell apoptosis. However, the regulatory mechanism of the signaling pathway remains unclear. We hypothesize that the regulatory mechanisms are mediated by the protein kinase-like endoplasmic reticulum kinase/euka...

journal_title：Neural regeneration research

authors： Yang JW,Hu ZP

更新日期：2015-08-01 00:00:00

abstract：:Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of debilitating disorders with multifactorial etiologies and pathogeneses that manifest distinct molecular mechanisms and clinical manifestations with abnormal ...

journal_title：Neural regeneration research

authors： Onyango IG,Bennett JP,Stokin GB

更新日期：2021-08-01 00:00:00

abstract：:A growing body of evidence suggests that disruption of the homeostasis of lipid metabolism affects the pathogenesis of Alzheimer's disease (AD). In particular, dysregulation of cholesterol homeostasis in the brain has been reported to considerably increase the risk of developing AD. Thus, dysregulation of lipid homeos...

journal_title：Neural regeneration research

authors： Li HH,Lin CL,Huang CN

更新日期：2018-02-01 00:00:00

abstract：:Excessive radiation exposure may lead to edema of the spinal cord and deterioration of the nervous system. Magnetic resonance imaging can be used to judge and assess the extent of edema and to evaluate pathological changes and thus may be used for the evaluation of spinal cord injuries caused by radiation therapy. Rad...

journal_title：Neural regeneration research

authors： Cao X,Fang L,Cui CY,Gao S,Wang TW

更新日期：2018-03-01 00:00:00

abstract：:The precedence effect is a prerequisite for faithful sound localization in a complex auditory environment, and is a physiological phenomenon in which the auditory system selectively suppresses the directional information from echoes. Here we investigated how neurons in the inferior colliculus respond to the paired sou...

journal_title：Neural regeneration research

authors： Wang Y,Wang N,Wang D,Jia J,Liu J,Xie Y,Wen X,Li X

更新日期：2014-02-15 00:00:00

abstract：:Curcumin exerts a neuroprotective effect on Alzheimer's disease; however, it is not known whether microRNAs are involved in this protective effect. This study was conducted using swAPP695-HEK293 cells as an Alzheimer's disease cell model. swAPP695-HEK293 cells were treated with 0, 0.5, 1, 2, 5, and 10 μM curcumin for ...

journal_title：Neural regeneration research

authors： Liu HY,Fu X,Li YF,Li XL,Ma ZY,Zhang Y,Gao QC

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effectiveness and safety of stem cell transplantation for spinal cord injury (SCI). DATA SOURCES:PubMed, EMBASE, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, Wanfang, and SinoMed databases were systematically searched by co...

journal_title：Neural regeneration research

authors： Fan X,Wang JZ,Lin XM,Zhang L

更新日期：2017-05-01 00:00:00

abstract：:This study sought to investigate the effects of Purendan superfine powder comprised of Momordica charantia, Radix Ginseng, and Radix Salviae Miltiorrhiae on neuronal apoptosis and expression of bcl-2, bax, and caspase-3, which are retinal apoptosis-associated factors in rats with diabetes mellitus induced by continuou...

journal_title：Neural regeneration research

authors： Dong Z,Tao X,Fu X,Wang H,Wang D,Zhang T

更新日期：2012-01-25 00:00:00

abstract：:Proximal or middle lesions of the ulnar or median nerves are responsible for extensive loss of hand motor function. This occurs even when the most meticulous microsurgical techniques or nerve grafts are used. Previous studies had proposed that nerve transfer was more effective than nerve grafting for nerve repair. Our...

journal_title：Neural regeneration research

authors： Wang PJ,Zhang Y,Zhao JJ,Zhou JP,Zuo ZC,Wu BB

更新日期：2017-01-01 00:00:00

abstract：:No recommended guidelines currently exist for the therapeutic concentration or dose of botulinum toxin type A (BTXA) injected into the muscle to treat limb spasticity. Therefore, in this randomized controlled trial, we explored the safety and efficacy of two concentrations and two doses of BTXA in the treatment of spa...

journal_title：Neural regeneration research

authors： Li J,Zhang R,Cui BL,Zhang YX,Bai GT,Gao SS,Li WJ

更新日期：2017-09-01 00:00:00

abstract：:[This corrects the article on p. 1386 in vol. 10, PMID: 26604888.]. ...

journal_title：Neural regeneration research

authors：

更新日期：2016-07-01 00:00:00

abstract：:Multiple mononeuropathy is an unusual form of peripheral neuropathy involving two or more nerve trunks. It is a syndrome with many different causes. We reviewed the clinical, electrophysiological and nerve biopsy findings of 14 patients who suffered from multiple mononeuropathy in our clinic between January 2009 and J...

journal_title：Neural regeneration research

authors： Zhang YS,Sun AP,Chen L,Dong RF,Zhong YF,Zhang J

更新日期：2015-01-01 00:00:00

abstract：:Amniotic membranes have been widely used in ophthalmology and skin injury repair because of their anti-inflammatory properties. In this study, we measured therapeutic efficacy and determined if amniotic membranes could be used for facial nerve repair. The facial nerves of eight rats were dissected and end-to-end anast...

journal_title：Neural regeneration research

authors： Karaman M,Tuncel A,Sheidaei S,Senol MG,Karabulut MH,Deveci I,Karaman N

更新日期：2013-04-15 00:00:00

abstract：:Recent studies have shown that induced expression of endogenous antioxidative enzymes thr-ough activation of the antioxidant response element/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway may be a neuroprotective strategy. In this study, rat cerebral cortical neurons cultured in vitro were pretreated with...

journal_title：Neural regeneration research

authors： Wu JX,Zhang LY,Chen YL,Yu SS,Zhao Y,Zhao J

更新日期：2015-03-01 00:00:00

abstract：:Yizhijiannao granules have been shown to improve cognitive function in Alzheimer's disease patients. The present study sought to explore the mechanisms involved in the cognitive enhancing effects of Yizhijiannao granule. Senescence-accelerated mouse prone 8 mice with learning and memory disorders were intragastrically...

journal_title：Neural regeneration research

authors： Zhu H,Luo L,Hu S,Dong K,Li G,Zhang T

更新日期：2014-07-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the older population, however, the precise cause of the disease is unknown. The neuropathology is characterized by the presence of aggregates formed by amyloid-β (Aβ) peptide and phosphorylated tau; which is accompanied by progressive impairment of memory...

journal_title：Neural regeneration research

authors： Tapia-Rojas C,Inestrosa NC

更新日期：2018-10-01 00:00:00

abstract：:This study compared the difference in brain structure in 12 mine disaster survivors with chronic post-traumatic stress disorder, 7 cases of improved post-traumatic stress disorder symptoms, and 14 controls who experienced the same mine disaster but did not suffer post-traumatic stress disorder, using the voxel-based m...

journal_title：Neural regeneration research

authors： Tan L,Zhang L,Qi R,Lu G,Li L,Liu J,Li W

更新日期：2013-09-15 00:00:00

abstract：:Growth arrest-specific 5 (GAS5) is an anti-oncogene that has been extensively studied in tumors. However, research on GAS5 in the context of nervous system disease is rare at present. This study aimed to investigate the role of the long non-coding RNA GAS5 in rat pheochromocytoma cells (PC12 cells). GAS5-overexpressin...

journal_title：Neural regeneration research

authors： Zhao HY,Zhang ST,Cheng X,Li HM,Zhang L,He H,Qin JB,Zhang WY,Sun Y,Jin GH

更新日期：2019-12-01 00:00:00

abstract：:In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical stimulation. Electrical stimulation upregulated the expression levels of orexin-A and its receptor OX1R ...

journal_title：Neural regeneration research

authors： Feng Z,Zhong YJ,Wang L,Wei TQ

更新日期：2015-04-01 00:00:00

abstract：:Previous studies demonstrate an accumulation of transferrin and transferrin receptor 1 (TfR1) in regenerating peripheral nerves. However, the expression and function of transferrin and TfR1 in the denervated skeletal muscle remain poorly understood. In this study, a mouse model of denervation was produced by complete ...

journal_title：Neural regeneration research

authors： Li Y,Cheng JX,Yang HH,Chen LP,Liu FJ,Wu Y,Fan M,Wu HT

更新日期：2021-07-01 00:00:00

abstract：:Human umbilical mesenchymal stem cells from Wharton's jelly of the umbilical cord were induced to differentiate into oligodendrocyte precursor-like cells in vitro. Oligodendrocyte precursor cells were transplanted into contused rat spinal cords. Immunofluorescence double staining indicated that transplanted cells surv...

journal_title：Neural regeneration research

authors： Chen H,Zhang Y,Yang Z,Zhang H

更新日期：2013-04-05 00:00:00

abstract：:Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold mater...

journal_title：Neural regeneration research

authors： Zhang PX,Han N,Kou YH,Zhu QT,Liu XL,Quan DP,Chen JG,Jiang BG

更新日期：2019-01-01 00:00:00

abstract：:Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system with all body systems. In many neurodegenerative diseases, neurons pack toxic substan...

journal_title：Neural regeneration research

authors： Shaimardanova AA,Solovyeva VV,Chulpanova DS,James V,Kitaeva KV,Rizvanov AA

更新日期：2020-04-01 00:00:00

abstract：:We report a patient with severe ataxia due to Dandy-Walker malformation, who showed functional recovery over 10 months corresponding to a change in a cerebellar peduncle lesion. A 20-month-old female patient who was diagnosed with Dandy-Walker syndrome and six age- and sex-matched healthy control subjects were enrolle...

journal_title：Neural regeneration research

authors： Lee AY,Jang SH,Yeo SS,Lee E,Cho YW,Son SM

更新日期：2013-02-15 00:00:00

abstract：:The three-dimensional (3D) visualization of the functional bundles in the peripheral nerve provides direct and detailed intraneural spatial information. It is useful for selecting suitable surgical methods to repair nerve defects and in optimizing the construction of tissue-engineered nerve grafts. However, there rema...

journal_title：Neural regeneration research

authors： Qi J,Wang WY,Zhong YC,Zhou JM,Luo P,Tang P,He CF,Zhu S,Liu XL,Zhang Y

更新日期：2018-08-01 00:00:00

abstract：:Among the various treatment methods for stroke, increasing attention has been paid to traditional Chinese medicines. Buyang Huanwu decoction is a commonly used traditional Chinese medicine for the treatment of stroke. This paper summarizes the active components of the Chinese herb, which is composed of Huangqi (Radix ...

journal_title：Neural regeneration research

authors： Mu Q,Liu P,Hu X,Gao H,Zheng X,Huang H

更新日期：2014-09-01 00:00:00

abstract：:There are several major pathological changes in Alzheimer's disease, including apoptosis of cholinergic neurons, overactivity or overexpression of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) and inflammation. In this study, we synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloi...

journal_title：Neural regeneration research

authors： Liu Z,Li S,Liang Z,Zhao Y,Zhang Y,Yang Y,Wang M,Li F

更新日期：2013-11-25 00:00:00