Hyperbaric oxygen therapy improves local microenvironment after spinal cord injury.

abstract：:Brain structure and cognitive function change in the temporal lobe, hippocampus, and prefrontal cortex of patients with mild cognitive impairment and Alzheimer's disease, and brain network-connection strength, network efficiency, and nodal attributes are abnormal. However, existing research has only analyzed the diffe...

journal_title：Neural regeneration research

authors： Xiang J,Guo H,Cao R,Liang H,Chen J

更新日期：2013-10-25 00:00:00

abstract：:Severe edema in the endoneurium can occur after non-freezing cold injury to the peripheral nerve, which suggests damage to the blood-nerve barrier. To determine the effects of cold injury on the blood-nerve barrier, the sciatic nerve on one side of Wistar rats was treated with low temperatures (3-5°C) for 2 hours. The...

journal_title：Neural regeneration research

authors： Li H,Jia JP,Xu M,Zhang L

更新日期：2015-03-01 00:00:00

abstract：:The baker's yeast Saccharomyces (S.) cerevisiae is a single-celled eukaryotic model organism widely used in research on life sciences. Being a unicellular organism, S. cerevisiae has some evident limitations in application to neuroscience. However, yeast prions are extensively studied and they are known to share some ...

journal_title：Neural regeneration research

authors： Ishikawa T

更新日期：2021-03-01 00:00:00

abstract：:Magnesium (Mg) wire has been shown to be biodegradable and have anti-inflammatory properties. It can induce Schwann cells to secrete nerve growth factor and promote the regeneration of nerve axons after central nervous system injury. We hypothesized that biodegradable Mg wire may enhance compressed peripheral nerve re...

journal_title：Neural regeneration research

authors： Li BH,Yang K,Wang X

更新日期：2016-12-01 00:00:00

abstract：:A growing body of evidence suggests that disruption of the homeostasis of lipid metabolism affects the pathogenesis of Alzheimer's disease (AD). In particular, dysregulation of cholesterol homeostasis in the brain has been reported to considerably increase the risk of developing AD. Thus, dysregulation of lipid homeos...

journal_title：Neural regeneration research

authors： Li HH,Lin CL,Huang CN

更新日期：2018-02-01 00:00:00

abstract：:Traumatic brain injury can cause loss of neuronal tissue, remote symptomatic epilepsy, and cognitive deficits. However, the mechanisms underlying the effects of traumatic brain injury are not yet clear. Hippocampal excitability is strongly correlated with cognitive dysfunction and remote symptomatic epilepsy. In this ...

journal_title：Neural regeneration research

authors： Zhang BL,Fan YS,Wang JW,Zhou ZW,Wu YG,Yang MC,Sun DD,Zhang JN

更新日期：2018-10-01 00:00:00

abstract：:Intrinsically disordered proteins, such as tau or α-synuclein, have long been associated with a dysfunctional role in neurodegenerative diseases. In Alzheimer's and Parkinson's' diseases, these proteins, sharing a common chemical-physical pattern with alternating hydrophobic and hydrophilic domains rich in prolines, a...

journal_title：Neural regeneration research

authors： Caminati G,Procacci P

更新日期：2020-12-01 00:00:00

abstract：:The locus coeruleus is a pontine nucleus that produces much of the brain's norepinephrine. Despite its small size, the locus coeruleus is critical for a myriad of functions and is involved in many neurodegenerative and neuropsychiatric disorders. In this review, we discuss the physiology and anatomy of the locus coeru...

journal_title：Neural regeneration research

authors： Bari BA,Chokshi V,Schmidt K

更新日期：2020-06-01 00:00:00

abstract：:This study aimed to summarize therapy experience of carotid endarterectomy, carotid endarterectomy combined with Fogarty catheter embolectomy, and hybrid surgery for the treatment of extracranial internal carotid artery occlusion. The study included 65 patients with extracranial internal carotid artery occlusion who u...

journal_title：Neural regeneration research

authors： Jiao L,Song G,Hua Y,Ma Y,Chen Y,Wang Y,Ling F

更新日期：2013-08-15 00:00:00

abstract：:Genome-wide studies have reported that Parkinson's disease is associated with abnormal expression of various growth factors. In this study, male C57BL/6 mice aged 10 weeks were used to establish Parkinson's disease models using an intraperitoneal injection of 60 mg/kg 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. 28 d...

journal_title：Neural regeneration research

authors： Wang AQ,Kong LN,Meng MZ,Zhao XH,Chen S,Wang XT

更新日期：2019-08-01 00:00:00

abstract：:Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair. Previous studies have shown that human amniotic membrane can promote t...

journal_title：Neural regeneration research

authors： Zhang ZY,Yang J,Fan ZH,Wang DL,Wang YY,Zhang T,Yu LM,Yu CY

更新日期：2019-12-01 00:00:00

abstract：:The capability of neurons to discriminate between intensity of external stimulus is measured by its dynamic range. A larger dynamic range indicates a greater probability of neuronal survival. In this study, the potential roles of adaptation mechanisms (ion currents) in modulating neuronal dynamic range were numericall...

journal_title：Neural regeneration research

authors： Wang L,Wang Y,Fu WL,Cao LH

更新日期：2017-03-01 00:00:00

abstract：:[This corrects the article on p. 1386 in vol. 10, PMID: 26604888.]. ...

journal_title：Neural regeneration research

authors：

更新日期：2016-07-01 00:00:00

abstract：:Previous studies have demonstrated the protective effect of hypoxic preconditioning on acute cerebral infarction, but the mechanisms underlying this protection remain unclear. To investigate the protective mechanisms of hypoxic preconditioning in relation to its effects on angiogenesis, we induced a photochemical mode...

journal_title：Neural regeneration research

authors： Li S,Zhang Y,Shao G,Yang M,Niu J,Lv G,Ji X

更新日期：2013-11-05 00:00:00

abstract：:Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredoxin (TRX) using mole...

journal_title：Neural regeneration research

authors： Wang X,Yang Y,Jia M,Ma C,Wang M,Che L,Yang Y,Wu J

更新日期：2013-01-05 00:00:00

abstract：:Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction. Cellular edema and aquaporin-4 expression can be determined by measuring cerebral infar...

journal_title：Neural regeneration research

authors： He ZP,Lu H

更新日期：2015-07-01 00:00:00

abstract：:Excessive radiation exposure may lead to edema of the spinal cord and deterioration of the nervous system. Magnetic resonance imaging can be used to judge and assess the extent of edema and to evaluate pathological changes and thus may be used for the evaluation of spinal cord injuries caused by radiation therapy. Rad...

journal_title：Neural regeneration research

authors： Cao X,Fang L,Cui CY,Gao S,Wang TW

更新日期：2018-03-01 00:00:00

abstract：:We have previously shown that induction of ketosis by ketogenic diet (KD) conveyed neuroprotection following spinal cord injury in rodent models, however, clinical translation may be limited by the slow raise of ketone levels when applying KD in the acute post-injury period. Thus we investigated the use of exogenous k...

journal_title：Neural regeneration research

authors： Tan BT,Jiang H,Moulson AJ,Wu XL,Wang WC,Liu J,Plunet WT,Tetzlaff W

更新日期：2020-10-01 00:00:00

abstract：:Previous studies demonstrate an accumulation of transferrin and transferrin receptor 1 (TfR1) in regenerating peripheral nerves. However, the expression and function of transferrin and TfR1 in the denervated skeletal muscle remain poorly understood. In this study, a mouse model of denervation was produced by complete ...

journal_title：Neural regeneration research

authors： Li Y,Cheng JX,Yang HH,Chen LP,Liu FJ,Wu Y,Fan M,Wu HT

更新日期：2021-07-01 00:00:00

abstract：:Spinal cord injury that results in severe neurological disability is often incurable. The poor clinical outcome of spinal cord injury is mainly caused by the failure to reconstruct the injured neural circuits. Several intrinsic and extrinsic determinants contribute to this inability to reconnect. Epigenetic regulation...

journal_title：Neural regeneration research

authors： Zhang BY,Chang PY,Zhu QS,Zhu YH,Saijilafu.

更新日期：2020-09-01 00:00:00

abstract：:Septic encephalopathy is a frequent complication of sepsis, but there are few studies examining the role of microRNAs (miRs) in its pathogenesis. In this study, a miR-219 mimic was transfected into rat hippocampal neurons to model miR-219 overexpression. A protective effect of miR-219 was observed for glutamate-induce...

journal_title：Neural regeneration research

authors： Wang T,Cai Q,Yang WJ,Fan HH,Yi JF,Xu F

更新日期：2018-07-01 00:00:00

abstract：:Peripheral and central sensitizations are phenomena that occur during migraine. The role of pentin, a migraine preventive drug, on central sensitization remains unclear. In this study, a rat model of migraine was established by electrical stimulation of the trigeminal ganglion, and the an-imals were given intragastric...

journal_title：Neural regeneration research

authors： Zhang Y,Shao G,Zhang W,Li S,Niu J,Hu D,Yang M,Ji X

更新日期：2013-11-15 00:00:00

abstract：:Rehmannia has been shown to be clinically effective in treating neurodegenerative diseases; however, the neuroprotective mechanisms remain unclear. In this study, we established a model of neurodegenerative disease using PC12 cytotoxic injury induced by glutamate. The cells were treated with 20 mM glutamate in the abs...

journal_title：Neural regeneration research

authors： Liu Y,Liu L,Ying XX,Wei WJ,Han C,Liu Y,Han CH,Leng AJ,Ma JY,Liu J

更新日期：2017-08-01 00:00:00

abstract：:To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted interviews. Dissociative amnesia is one of the indications for these interviews. Herein, we present the case o...

journal_title：Neural regeneration research

authors： Seo Y,Shin MH,Kim SG,Kim JH

更新日期：2013-01-15 00:00:00

abstract：:The electrical excitability of neural networks is influenced by different environmental factors. Effective and simple methods are required to objectively and quantitatively evaluate the influence of such factors, including variations in temperature and pharmaceutical dosage. The aim of this paper was to introduce 'the...

journal_title：Neural regeneration research

authors： An S,Zhao YF,Lü XY,Wang ZG

更新日期：2018-06-01 00:00:00

abstract：:The main goal of spinal cord rehabilitation is to restore walking ability and improve walking quality after spinal cord injury (SCI). The spatiotemporal parameters of walking and the parameters of plantar pressure can be obtained using a plantar pressure analysis system. Previous studies have reported step asymmetry i...

journal_title：Neural regeneration research

authors： Yuan XN,Liang WD,Zhou FH,Li HT,Zhang LX,Zhang ZQ,Li JJ

更新日期：2019-02-01 00:00:00

abstract：:LIM homeobox transcription factor 1a (Lmx1a) has the capacity to initiate the development program of neuronal cells and promote the differentiation of embryonic stem cells into dopaminergic neurons. In this study, rhesus adipose stem cells were infected with recombinant adenovirus carrying the Lmx1a gene and co-cultur...

journal_title：Neural regeneration research

authors： Zhou Y,Sun M,Li H,Yan M,Xie T

更新日期：2012-12-05 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive treatment that can enhance the recovery of neurological function after stroke. Whether it can similarly promote the recovery of cognitive function after vascular dementia remains unknown. In this study, a rat model for vascular dementia was establis...

journal_title：Neural regeneration research

authors： Zhang XQ,Li L,Huo JT,Cheng M,Li LH

更新日期：2018-08-01 00:00:00

abstract：:Spinal cord injury is a major cause of disability with devastating neurological outcomes and limited therapeutic opportunities, even though there are thousands of publications on spinal cord injury annually. There are two major types of spinal cord injury, transaction of the spinal cord and spinal cord contusion. Both...

journal_title：Neural regeneration research

authors： Ju G,Wang J,Wang Y,Zhao X

更新日期：2014-04-15 00:00:00

abstract：:Traumatic brain injury survivors often experience cognitive deficits and neuropsychiatric symptoms. However, the neurobiological mechanisms underlying specific impairments are not fully understood. Advances in neuroimaging techniques (such as diffusion tensor imaging and functional MRI) have given us new insights on s...

journal_title：Neural regeneration research

authors： Xiao H,Yang Y,Xi JH,Chen ZQ

更新日期：2015-12-01 00:00:00