Abstract:
:We aimed to evaluate the effectiveness of temperature-controlled laser soldering for repair of large perforated corneas in a porcine model. Eight Yorkshire pigs aged 6 months underwent 6-mm-deep 180° crescent-shaped trephination of the central corneas. Right corneal injuries were repaired by placement of 47 % bovine albumin along the cut followed by CO2 laser soldering (power density 16 W/cm(2)) to a target temperature of 65(°). Left corneal injuries were repaired with 10/0 nylon sutures. The groups were compared for operative time, leakage, and histopathological findings. Mean tissue temperature was 63 ± 4 °C. Mean operative time was 31.57 ± 2.8 min in laser-soldered eyes and 41.38 ± 2.3 min in controls (p < 0.0001, unpaired Student's t test). Compared to controls, the soldered corneas had less neovascularization, complete re-epithelization, and mild stromal inflammation. There was no leakage in either group. Combined CO2 laser and radiometer is effective for the in vivo repair of corneal cuts. These results have important implications for modern corneal surgery. Further studies are needed in the clinical setting.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Tal K,Strassmann E,Loya N,Ravid A,Kariv N,Weinberger D,Katzir A,Gaton DDdoi
10.1007/s10103-015-1737-2subject
Has Abstractpub_date
2015-05-01 00:00:00pages
1367-71issue
4eissn
0268-8921issn
1435-604Xjournal_volume
30pub_type
杂志文章abstract::To determine the relation between retinal microstructural changes and the response to 577-nm subthreshold micropulse laser (SML) treatment in chronic central serous chorioretinopathy (cCSC). This retrospective study included 39 eyes of 39 patients with cCSC, treated with the 577-nm SML. The eyes were evaluated in thre...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03225-6
更新日期:2021-01-07 00:00:00
abstract::The purposes of the study were to evaluate the bond strength of bioceramic TotalFill root repair material (RRM) in retrograde cavities prepared using Er:YAG and Er,Cr:YSGG laser and steel bur, and to analyze failure modes. The root canals of 30 single-rooted teeth were endodontically treated, their root-ends were rese...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02835-z
更新日期:2020-02-01 00:00:00
abstract::Detection of demineralization of root surface caries is an important issue since preventive approaches prolong tooth life. Quantitative light-induced fluorescence (QLF) has been shown to be useful for the laboratory assessment of demineralization of root surfaces. The aim of this study was to determine the demineraliz...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0899-9
更新日期:2012-03-01 00:00:00
abstract::Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1207-z
更新日期:2013-07-01 00:00:00
abstract::Facial freckles are a cosmetic concern to Egyptians, particularly young females. Several therapeutic lines exist with variable response rates and limitations. Fractional carbon dioxide (FCO2) laser provides minimal ablation and therefore less down time and less side effects. The efficacy and safety of this laser techn...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1610-8
更新日期:2014-11-01 00:00:00
abstract::This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-012-1196-y
更新日期:2013-11-01 00:00:00
abstract::5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) provides a novel and promising treatment for esophageal cancer. However, its specific mechanism has not been fully elucidated and its efficacy is remarkably varied. This study investigated the effect of ALA-PDT on esophageal squamous carcinoma cell line Eca...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0810-0
更新日期:2011-01-01 00:00:00
abstract::Excimer laser recanalisation of in-stent restenosis may be a viable modality for improving coronary patency. However, the presence of arterial stents modifies the thermal properties of the irradiated area and may alter temperature patterns generated during ablation. The goal of this study was to evaluate, in vitro, te...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/pl00011348
更新日期:2001-01-01 00:00:00
abstract::Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0511-5
更新日期:2008-10-01 00:00:00
abstract::Lasers have many favorable features as a light source owing to their monochromaticity and coherence. This study examined the mechanical properties of composite resins that were light-cured using a diode-pumped solid state (DPSS) laser. Eight composite resins were light-cured using four different light sources (one qua...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1117-0
更新日期:2013-02-01 00:00:00
abstract::This study aimed to investigate the influence of low-power 830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated with bioactive glass graft material. Twenty patients with chronic pe...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-008-0576-9
更新日期:2009-05-01 00:00:00
abstract::The purpose of this study was to compare the effectiveness of 1470- and 980-nm lasers with regard to power output, complications, recanalization rates, and treatment response. We prospectively evaluated the effectiveness of endovenous laser ablation (EVLA) in a total of 152 great and small saphenous veins from 96 pati...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1768-8
更新日期:2015-07-01 00:00:00
abstract::Third-degree burn wounds are considered severe injuries because they destroy all the skin layers and may affect subcutaneous tissues, fasciae, muscles, and bones. To favor the healing process of the injured tissues, it is very useful to diminish the occurrence of the inflammatory process. The present study was aimed a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1213-1
更新日期:2013-07-01 00:00:00
abstract::Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve con...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03095-y
更新日期:2020-07-07 00:00:00
abstract::Laser therapy has proved effective in the treatment of different tissue injuries but little is known about its effect on the testis. The aim of this review was to synthesize research on the in vivo effect of low-level laser therapy on the seminiferous epithelium. A search was performed in the PubMed/Medline, Scopus, W...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-020-03122-y
更新日期:2020-08-19 00:00:00
abstract::Laser beam deflection is a useful tool for studying the dynamics of the pulsed laser ablation mechanism, and has the advantage of being used as an in situ laser damage monitoring technique for both bulk and thin film polymeric and biological tissue samples. This work employs the photothermal deflection technique to st...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/BF02767153
更新日期:1997-12-01 00:00:00
abstract::Selecting the most representative site for biopsy is crucial in establishing a definitive diagnosis of oral epithelial dysplasia. The current process involves clinical examination that can be subjective and prone to sampling errors. The aim of this study was therefore to investigate the use of optical coherence tomogr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0975-1
更新日期:2012-07-01 00:00:00
abstract::Two-photon excited fluorescence (TPEF) microscopy, based on signal from cells, can provide detailed information on tissue architecture and cellular morphology in unstained histological sections to generate subcellular-resolution images from tissue directly. In this paper, we used TPEF microscopy to image microstructur...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1652-y
更新日期:2015-01-01 00:00:00
abstract::Papacarie Duo™ is clinically used and has proven effectiveness; however, it is necessary to improve its antimicrobial action. The combined treatment of Papacarie Duo™ with Urucum (Bixa Orellana) could create a potential tool for dental caries treatment; its extract obtained from the seeds' pericarp contains a water-so...
journal_title:Lasers in medical science
pub_type: 信件
doi:10.1007/s10103-019-02857-7
更新日期:2020-04-01 00:00:00
abstract::Nitrogen laser-induced fluorescence (LIF) and tungsten halogen lamp excited diffuse reflectance spectra were recorded in 350- to 700-nm range on a miniature fiber-optic spectrometer from in vitro premolar tooth during various stages of artificial erosion with 36% phosphoric acid. Both the LIF spectral intensity and th...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0489-z
更新日期:2008-07-01 00:00:00
abstract::To evaluate the efficacy and safety of holmium laser enucleation of prostate (HoLEP) for treating urinary retention in patients with advanced prostate cancer. Thirty-eight cases of advanced prostate cancer with urinary retention were enrolled in this retrospective study. All the 38 patients were treated with CAB as a ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02913-2
更新日期:2020-08-01 00:00:00
abstract::The aim of this in vitro study was to determine the effect of different remineralization agents and laser on caries resistance of primary enamel. In the study, 150 sound primary molars were used. The initial microhardness values were measured and the teeth were randomly assigned to ten treatment groups (n = 15): no tr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2667-6
更新日期:2019-07-01 00:00:00
abstract::Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroid...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-013-1313-6
更新日期:2014-01-01 00:00:00
abstract::Crohn's disease is a chronic relapsing and remitting inflammatory condition which affects any part of the gastrointestinal tract. In the oro-facial region, patients can present peri-oral swellings which results in severe facial disfigurement. To date, assessing the degree of facial changes and evaluation of treatment ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1286-5
更新日期:2014-05-01 00:00:00
abstract::In the application of lasers in dentistry, there is a delicate balance between the benefits gained from laser treatment and the heat-related damage arising from laser irradiation. Hence, it is necessary to understand the different processes associated with the irradiation of lasers on dental materials. To obtain insig...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2251-5
更新日期:2017-08-01 00:00:00
abstract::Oxygen consumption at the targeted site has a significant effect on dosimetry in photodynamic therapy (PDT). However, oxygen consumption in PDT using a pulsed laser as a light source has not been clarified. We therefore investigated the dependence of cytotoxicity on the oxygen consumption and the photosensitizer photo...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-004-0288-8
更新日期:2004-01-01 00:00:00
abstract::This study aimed to evaluate the surface changes caused in zirconia by different surface treatments and the influence of the surface treatment and cement selection on bonding to zirconia under aging. Sintered zirconia specimens were divided into five groups (n = 31) based on the surface treatment, namely, control, air...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1221-1
更新日期:2014-01-01 00:00:00
abstract::There is concern that the delicate fibres and cylindrical diffuser tips used for intraluminal PDT of blood vessels might break during the treatment. We have developed and tested a simple system to monitor for fibre breakage during PDT. Light from the laser is passed through a beam expander, then a beam splitter, and t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-003-0270-x
更新日期:2003-01-01 00:00:00
abstract::Precise nerve localization is of major importance in both surgery and regional anesthesia. Optically based techniques can identify tissue through differences in optical properties, like absorption and scattering. The aim of this study was to evaluate the potential of optical spectroscopy (diffuse reflectance spectrosc...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2433-1
更新日期:2018-04-01 00:00:00
abstract::The neodymium/yttrium-aluminum-garnet (Nd/YAG) laser has been suggested to repair broken prostheses in the mouth. This study investigated the effects of different dentin thicknesses and air cooling on pulpal temperature rise during laser welding. Three intact human maxillary molars were prepared for full-veneer crown....
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1108-1
更新日期:2013-01-01 00:00:00