Abstract:
:Vertebrate eye formation is a multistep process requiring coordinated inductive interactions between neural and non-neural ectoderm and underlying mesendoderm. The induction and shaping of the eyes involves an elaborate cellular choreography characterized by precise changes in cell shape coupled with complex cellular and epithelial movements. Consequently, the forming eye is an excellent model to study the cellular mechanisms underlying complex tissue morphogenesis. Using examples largely drawn from recent studies of optic vesicle formation in zebrafish and in cultured embryonic stem cells, in this short review, we highlight some recent advances in our understanding of the events that shape the vertebrate eye.
journal_name
Curr Opin Genet Devjournal_title
Current opinion in genetics & developmentauthors
Bazin-Lopez N,Valdivia LE,Wilson SW,Gestri Gdoi
10.1016/j.gde.2015.02.004subject
Has Abstractpub_date
2015-06-01 00:00:00pages
73-9eissn
0959-437Xissn
1879-0380pii
S0959-437X(15)00016-7journal_volume
32pub_type
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journal_title:Current opinion in genetics & development
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journal_title:Current opinion in genetics & development
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journal_title:Current opinion in genetics & development
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journal_title:Current opinion in genetics & development
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journal_title:Current opinion in genetics & development
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