Procoagulant cellular activity (PCA) in the classification of acute leukemia.

abstract：:Factor IX Nagoya 3 (IX Nagoya 3) is a natural mutant of factor IX recognized in a patient with moderately severe hemophilia B. The patient had 0.60 units/ml of factor IX antigen and 2-5% of clotting activity. IX Nagoya 3 was purified from the patient's plasma by immunoaffinity chromatography with an anti-factor IX mon...

journal_title：Thrombosis research

authors： Suehiro K,Miyata T,Takeya H,Takamatsu J,Saito H,Murakawa M,Okamura T,Niho Y,Iwanaga S

更新日期：1990-11-15 00:00:00

abstract：INTRODUCTION:Quercetin is widely distributed in plants and has been reported to have effects of anti-inflammation and anti-thrombosis. In this study, we evaluated the protective effect of quercetin on LPS-induced experimental DIC in rabbits, and tried to clarify its mechanism against DIC. MATERIALS AND METHODS:LPS-ind...

journal_title：Thrombosis research

authors： Yu PX,Zhou QJ,Zhu WW,Wu YH,Wu LC,Lin X,Chen MH,Qiu BT

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Troponin I (cTnI), myoglobin, heart-type fatty acid binding protein (H-FABP), and natriuretic peptides (BNP, NTproBNP) were all reported to be elevated in patients with pulmonary embolism (PE). METHODS:To assess the correlation between the aforementioned markers and helical computed tomography (hCT) right v...

journal_title：Thrombosis research

authors： Vuilleumier N,Righini M,Perrier A,Rosset A,Turck N,Sanchez JC,Bounameaux H,Le Gal G,Mensi N,Hochstrasser D

更新日期：2008-01-01 00:00:00

abstract：:Selective serotonin reuptake inhibitors (SSRIs) have been reported to reduce platelet aggregation induced by ADP. ADP induces platelet aggregation through two purinergic receptors P2Y1 and P2Y12. We characterized the inhibitory properties of SSRIs on ADP-induced platelet aggregation and investigated the effects of SSR...

journal_title：Thrombosis research

authors： Tseng YL,Chiang ML,Lane HY,Su KP,Lai YC

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Plasma coagulation Factor XII (FXII) plays a crucial role in contact activation, ultimately regulating both the kinin-kallikrein system and the intrinsic pathway of coagulation. A growing body of evidence suggests that inhibition of FXII can prevent thrombosis. Given FXII does not appear to modulate hemostas...

journal_title：Thrombosis research

authors： Liu J,Cooley BC,Akinc A,Butler J,Borodovsky A

更新日期：2020-12-01 00:00:00

abstract：:The cerebral vascular supply is constructed to protect the cerebral hemispheres and brainstem from the consequences of blood flow cessation. Reversal of blood flow around local obstructions is a feature of the microvascular beds of the striatum and cerebral cortex. Cerebral capillaries of these beds consist of endothe...

journal_title：Thrombosis research

authors： del Zoppo GJ,Hallenbeck JM

更新日期：2000-05-01 00:00:00

abstract：:Numerous factors affect the response to vitamin K antagonists (VKA) including age, dietary vitamin K, other drugs, pharmacogenetics, and disease states. In antithrombotic guidelines, fever is mentioned as a factor that may increase response to VKA. The purpose of this article is to review the available evidence regard...

journal_title：Thrombosis research

authors： Self TH,Oliphant CS,Reaves AB,Richardson AM,Sands CW

更新日期：2015-01-01 00:00:00

abstract：:The effects of locally deposited fibrin and of tranexamic acid-induced antifibrinolysis on forming granulation tissue were studied in the light of a recently developed method for treatment of postoperative fistulas by occlusion with a fibrin clot. Perforated teflon cylinders, either empty or fibrin-filled, were implan...

journal_title：Thrombosis research

authors： Hedelin H,Teger-Nilsson AC,Peterson HI,Pettersson S

更新日期：1984-01-01 00:00:00

abstract：:A 15 year-aged Japanese girl with a life long mild purpura was found as a variant type of thrombasthenia. Basic tests revealed prolonged bleeding time, border-line clot retraction, no coagulation defect, no giant platelets and mild thrombocytopenia (70,000-110,000/microliters). Neither ADP, epinephrine nor collagen ag...

journal_title：Thrombosis research

authors： Tanoue K,Hasegawa S,Yamaguchi A,Yamamoto N,Yamazaki H

更新日期：1987-08-01 00:00:00

abstract：:There is growing evidence on the superior efficacy and safety of low molecular weight heparins (LMWHs) over unfractionated heparin (UFH) for the treatment of both venous and arterial thromboembolism. Heparin exerts its function by potentiating antithrombin and by mobilizing tissue factor pathway inhibitor (TFPI) into ...

journal_title：Thrombosis research

authors： Hansen JB,Sandset PM

更新日期：1998-08-15 00:00:00

abstract：:Ovarian hyperstimulation syndrome (OHSS) affects 5% of IVF cycles and incurs a 100-fold increase in risk of venous thrombosis over natural conceptions. Identification of women at risk of OHSS can be achieved using antral follicle count (AFC) and anti-Müllerian hormone (AMH). For those women with a high AFC or AMH comb...

journal_title：Thrombosis research

authors： Nelson SM

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:A poor implementation of VTE prophylactic measures recommended for critically ill patients has been observed in several epidemiological studies. The clinical factors associated with this have not been clearly established. The objective of our study was to identify which factors could be related to the inappropr...

journal_title：Thrombosis research

authors： García-Olivares P,Guerrero JE,Keough E,Galdos P,Carriedo D,Murillo F,Rivera A,PROF-ETEV study investigators.

更新日期：2016-07-01 00:00:00

abstract：:S-antigen (also named arrestin or 48K protein) is a protein abundant in photoreceptor cells of vertebrates and invertebrates. The presently known function of this protein in retina is to arrest the enzymatic cascade of phototransduction in retinal rods, through its binding to photoactivated and phosphorylated rhodopsi...

journal_title：Thrombosis research

authors： Mirshahi M,Razaghi A,Mirshahi SS,Van Tuyen V,Faure JP

更新日期：1991-12-01 00:00:00

abstract：:Cell lysates of the human monoblastic leukemia cell line, THP-1, have procoagulant activity (PCA) that is Ca++-dependent and not demonstrable in either Factor VII-, or Factor X-deficient plasma. The PCA of THP-1 cells was enhanced by human recombinant tumor necrosis factor-alpha (TNF-alpha) up to five fold. There was ...

journal_title：Thrombosis research

authors： Tanaka M

更新日期：1989-10-15 00:00:00

abstract：:Atherothrombosis is the leading cause of morbidity and mortality in patients with diabetes mellitus. Several mechanisms contribute to the diabetic prothrombotic state, including endothelial dysfunction, coagulative activation and platelet hyper-reactivity. In particular, diabetic platelets are characterised by dysregu...

journal_title：Thrombosis research

authors： Vazzana N,Ranalli P,Cuccurullo C,Davì G

更新日期：2012-03-01 00:00:00

abstract：:Protein C (PC) is the central protein in a major antithrombotic regulatory mechanism. Hereditary deficiencies of PC are associated with thrombosis. Therapeutic PC replacement may be an important treatment if pure functional human protein C is available in sufficient quantity. Human PC has been produced on a commercial...

journal_title：Thrombosis research

authors： Madden RM,Oppenheimer C,Wydro R,Marlar RA

更新日期：1990-02-01 00:00:00

abstract：:Fibrillar collagen endows the normal aortic wall with significant stiffness and strength and similarly plays important roles in many disease processes. For example, because of the marked loss of elastic fibers and functional smooth cells in aortic aneurysms, collagen plays a particularly important role in controlling ...

journal_title：Thrombosis research

authors： Schriefl AJ,Collins MJ,Pierce DM,Holzapfel GA,Niklason LE,Humphrey JD

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Pulmonary embolism (PE) is diagnosed with imaging techniques such as ventilation/perfusion (V/P) lung scintigraphy or multidetector computed tomography of the pulmonary arteries (MDCT). Lung scintigraphy can be performed with planar (V/P PLANAR) and tomographic (V/P SPECT) techniques. V/P SPECT has higher se...

journal_title：Thrombosis research

authors： Alhadad A,Miniati M,Alhadad H,Gottsäter A,Bajc M

更新日期：2012-12-01 00:00:00

abstract：:In 51 shock patients with DIC Antithrombin III (AT III) substitution, heparin or a combination of both substances respectively was administered. In the two groups which had been given AT III substitution the concentration of AT III rose considerably higher than the activity. There was a drop of the platelet count in b...

journal_title：Thrombosis research

authors： Blauhut B,Kramar H,Vinazzer H,Bergmann H

更新日期：1985-07-01 00:00:00

abstract：:Prothrombin time is a standard screening test to monitor patients treated with oral anticoagulants. We hypothesize that INR measurements will not vary a lot within a given day in a given patient. The present study was thus conducted to compare the change of the international normalized ratio (INR) of prothrombin time ...

journal_title：Thrombosis research

authors： Ho CH,Lin MW,You JY,Chen CC,Yu TJ

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Upon platelet stimulation with agonists, reactive oxygen species (ROS) generation enhances platelet activation and granule release. Whether ROS generation during platelet storage could be directly correlated with the expression of proinflammatory molecules and granule release has been investigated in this st...

journal_title：Thrombosis research

authors： Ghasemzadeh M,Hosseini E

更新日期：2017-08-01 00:00:00

abstract：:The in vitro and in vivo pharmacological properties of two oversulfated dermatan sulfate (DS) derivatives, S-DS1 and S-DS2, containing 2 and 3.7 sulfate groups/disaccharide unit respectively were compared to those of the parent DS (1 sulfate group/disaccharide unit). In a purified system the ability of S-DS1 and of S-...

journal_title：Thrombosis research

authors： Dol F,Caranobe C,Dupouy D,Petitou M,Lormeau JC,Choay J,Sié P,Boneu B

更新日期：1988-10-15 00:00:00

abstract：:Preanalytical and biological variability both have strong influences on test results of coagulation. Beyond age and gender, increasing emphasis is now being given to a variety of demographic and lifestyle variables, including ethnicity, smoking, diet, and exercise, which should be taken into account when interpreting ...

journal_title：Thrombosis research

authors： Lippi G,Favaloro EJ,Franchini M,Guidi GC

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Incidence and risk factors of venous thromboembolism (VTE) are well established in surgical and medical settings, but data in psychiatric units are lacking. The aim of this study was to estimate the incidence of VTE in hospitalized psychiatric patients, and to assess the risk factors for VTE in this specif...

journal_title：Thrombosis research

authors： Delluc A,Montavon S,Canceil O,Carpentier M,Nowak E,Mercier B,Bressollette L,Etienne S,Walter M,Mottier D,Lacut K

更新日期：2012-12-01 00:00:00

abstract：:Isolated rat liver macrophages (Kupffer cells) produce a factor(s) which stimulates fibrinogen synthesis 5-8 fold in hepatocyte cultures. The production of the stimulatory factor reached maximum during the first 24 hours the cells were in culture. When the cell culture medium was chromatographed on a calibrated Sephad...

journal_title：Thrombosis research

authors： Sanders KD,Fuller GM

更新日期：1983-10-15 00:00:00

abstract：:The effect of warfarin-induced factor VII deficiency on the skin bleeding time was investigated in 10 consecutive patients with mean prothrombin times of 33 sec and factor VII levels of 7%. Bleeding times in all but one subject were entirely within the normal range. We conclude that warfarin administration, even to th...

journal_title：Thrombosis research

authors： Green D,Ts'ao CH

更新日期：1983-02-15 00:00:00

abstract：INTRODUCTION:von Willebrand factor (VWF) is synthesised in vascular endothelial cells and released into the plasma as unusually large VWF multimers (UL-VWFMs). Sinusoidal endothelial cells are a major target of ischaemia-reperfusion injury due to liver surgery. This study aimed to clarify the effect of hepatectomy on U...

journal_title：Thrombosis research

authors： Yoshikawa T,Nomi T,Sakai K,Hayakawa M,Hokuto D,Matsuo Y,Sho M,Matsumoto M

更新日期：2019-11-01 00:00:00

abstract：:A semi-synthetic 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine (alkylacetyl-GPC) was shown to be highly species selective in its capacity to cause platelet aggregation and serotonin release. No effects were elicited on the rat or mouse platelets while platelets from human, dog, cat, rabbit, guinea pig and horse were ...

journal_title：Thrombosis research

authors： Namm DH,Tadepalli AS,High JA

更新日期：1982-02-15 00:00:00

abstract：INTRODUCTION:Low levels of plasminogen activator inhibitor type 1 (PAI-1) have been associated with increased risk for perioperative bleeding in some case reports. The aim of this study was to investigate prospectively whether low PAI-1 activity increases the risk for perioperative bleeding in patients undergoing trans...

journal_title：Thrombosis research

authors： Agren A,Kolmert T,Wiman B,Schulman S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The treatment of venous thromboembolism (VTE) in cancer patients remains controversial. PURPOSE:The Italian Society for Thrombosis and Haemostasis (SISET) commissioned a project to develop clinical practice guidelines for the therapy of VTE in patients with malignancies. METHODS:Key questions about the tre...

journal_title：Thrombosis research

authors： Imberti D,Di Nisio M,Donati MB,Falanga A,Ghirarduzzi A,Guarneri D,Piovella F,Santoro RC,Baldini E,Zampogna S,Italian Society for Thrombosis and Haemostasis.

更新日期：2009-11-01 00:00:00