Which boys respond to stimulant medication? A controlled trial of methylphenidate in boys with disruptive behaviour.

Abstract:

:Thirty-eight boys, referred for psychiatric treatment because of serious problems of behaviour, underwent a double-blind, placebo-controlled, crossover trial of methylphenidate and placebo. Methylphenidate was an effective treatment over a 3-week period. A good response to methylphenidate was predicted by higher levels of inattentive and restless behaviour, impaired performance on tests of attention, clumsiness, younger age and by the absence of symptoms of overt emotional disorder. DSM-III and ICD-9 diagnoses of 'hyperactivity' were not good predictors. The results support the validity of a construct of hyperactivity in describing childhood psychopathology, but emphasize the need for a refinement of diagnostic criteria.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Taylor E,Schachar R,Thorley G,Wieselberg HM,Everitt B,Rutter M

doi

10.1017/s0033291700013039

subject

Has Abstract

pub_date

1987-02-01 00:00:00

pages

121-43

issue

1

eissn

0033-2917

issn

1469-8978

journal_volume

17

pub_type

临床试验,杂志文章
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    更新日期:1992-02-01 00:00:00

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    更新日期:1995-11-01 00:00:00

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    更新日期:2003-02-01 00:00:00

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    pub_type: 传,历史文章,杂志文章

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    更新日期:1992-05-01 00:00:00

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    更新日期:1981-11-01 00:00:00

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  • Neuroticism as a risk factor for schizophrenia.

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    更新日期:2001-08-01 00:00:00

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    authors: Farmer CJ,Snowden SA,Parsons V

    更新日期:1979-08-01 00:00:00

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    pub_type: 杂志文章,多中心研究

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    pub_type: 杂志文章

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    doi:10.1017/s003329170002732x

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    更新日期:1994-05-01 00:00:00

  • Effects of seeking compensation on the psychological health and recovery of injured patients: the role of stress vulnerability and injury-related disability.

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