Predictors of outcome in first-episode schizophrenia over the first 4 years of illness.

abstract：BACKGROUND:Cognitive remediation (CR) is an effective treatment for several psychiatric disorders. To date, there have been no published studies examining solely first-episode psychiatric cohorts, despite the merits demonstrated by early intervention CR studies. The current study aimed to assess the effectiveness of CR...

journal_title：Psychological medicine

authors： Lee RS,Redoblado-Hodge MA,Naismith SL,Hermens DF,Porter MA,Hickie IB

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The phenotypic stability of avoidant personality disorder (AVPD) and obsessive-compulsive personality disorder (OCPD) has previously been found to be moderate. However, little is known about the longitudinal structure of genetic and environmental factors for these disorders separately and jointly, and to wha...

journal_title：Psychological medicine

authors： Gjerde LC,Czajkowski N,Røysamb E,Ystrom E,Tambs K,Aggen SH,Ørstavik RE,Kendler KS,Reichborn-Kjennerud T,Knudsen GP

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...

journal_title：Psychological medicine

authors： Loeb E,El Asmar K,Trabado S,Gressier F,Colle R,Rigal A,Martin S,Verstuyft C,Fève B,Chanson P,Becquemont L,Corruble E

更新日期：2020-06-11 00:00:00

abstract：:In an effort to distil major findings about the nature of human ageing, seven propositions are presented as a guiding frame of reference. This propositional framework is then used to specify some conditions for a positive culture of old age and to advance one possible model of good psychological ageing. This model foc...

journal_title：Psychological medicine

authors： Baltes PB

更新日期：1991-11-01 00:00:00

abstract：:The validity of the twin method depends on the equal environment assumption (EEA)--that monozygotic (MZ) and dizygotic (DZ) twins are equally correlated in their exposure to environmental factors of aetiological importance for the trait under study. Parents may treat MZ twins more similarly than DZ twins thereby poten...

journal_title：Psychological medicine

authors： Kendler KS,Neale MC,Kessler RC,Heath AC,Eaves LJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:There has been much recent excitement about the possibility that some cases of psychosis may be wholly due to brain-reactive antibodies, with antibodies to N-methyl-D-aspartate receptor (NMDAR) and the voltage-gated potassium channel (VGKC)-complex reported in a few patients with first-episode psychosis (FEP...

journal_title：Psychological medicine

authors： Gaughran F,Lally J,Beck K,McCormack R,Gardner-Sood P,Coutinho E,Jacobson L,Lang B,Sainz-Fuertes R,Papanastasiou E,Di Forti M,Nicholson T,Vincent A,Murray RM

更新日期：2018-06-01 00:00:00

abstract：:The Geriatric Mental State and a new computerized diagnostic system, AGECAT, are briefly described. A nomenclature for designating cases for epidemiological work is introduced. Concordance between AGECAT and psychiatrists' diagnoses for these studies, hospital and community based (total of 541 subjects), achieved over...

journal_title：Psychological medicine

authors： Copeland JR,Dewey ME,Griffiths-Jones HM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...

journal_title：Psychological medicine

authors： Shang CY,Gau SS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD:Data on age at onset, g...

journal_title：Psychological medicine

authors： O'Mahony E,Corvin A,O'Connell R,Comerford C,Larsen B,Jones R,McCandless F,Kirov G,Cardno AG,Craddock N,Gill M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Counselling is frequently used in the management of common mental disorders (such as anxiety and depression) in primary care. However, there are concerns over the clinical effectiveness of counselling, both in comparison with usual general practitioner care, and with other treatments such as alternative psyc...

journal_title：Psychological medicine

authors： Bower P,Rowland N,Hardy R

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The prevalence and impact of motor coordination difficulties in children with copy number variants associated with neurodevelopmental disorders (ND-CNVs) remains unknown. This study aims to advance understanding of motor coordination difficulties in children with ND-CNVs and establish relationships between i...

journal_title：Psychological medicine

authors： Cunningham AC,Hall J,Owen MJ,van den Bree MBM

更新日期：2019-11-19 00:00:00

abstract：BACKGROUND:Previous studies support Beck's cognitive model of vulnerability to depression. However, the relationship between his cognitive triad and other clinical features and risk factors among those with major depression (MD) has rarely been systematically studied. METHOD:The three key cognitive symptoms of worthle...

journal_title：Psychological medicine

authors： Wang L,Liu L,Shi S,Gao J,Liu Y,Li Y,Zhang Z,Wang G,Zhang K,Tao M,Gao C,Li K,Wang X,Lv L,Jiang G,Wang X,Jia H,Zhang J,Lu C,Li Y,Li K,Hu C,Ning Y,Li Y,Sun J,Liu T,Zhang Y,Ha B,Tian H,Meng H,Hu J

更新日期：2013-11-01 00:00:00

abstract：:We have attempted to clarify clinical differentiating features of psychotic depression. Forty-six depressed subjects meeting DSM-III-R criteria for major depression with psychotic features were compared with (i) DSM-defined melancholic, (ii) Newcastle-defined endogenous, and (iii) a residual DSM-defined major depressi...

journal_title：Psychological medicine

authors： Parker G,Hadzi-Pavlovic D,Brodaty H,Austin MP,Mitchell P,Wilhelm K,Hickie I

更新日期：1995-07-01 00:00:00

abstract：:Individuals with high and low susceptibility to hypnosis were compared in a baseline condition and after instructions of hypnosis on tests of anterior left and right hemispheric functions--word fluency to letter categories, word fluency to semantic categories, design fluency and bilateral finger tapping dexterity. Wit...

journal_title：Psychological medicine

authors： Gruzelier J,Warren K

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder which frequently persists into adulthood. The primary goal of the current study was to (a) investigate attentional functions of stimulant medication-naïve adults with ADHD, and (b) investigate the effects of 6 weeks of methylphe...

journal_title：Psychological medicine

authors： Low AM,Vangkilde S,le Sommer J,Fagerlund B,Glenthøj B,Jepsen JRM,Bundesen C,Petersen A,Habekost T

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The excess mortality following first-contact psychosis is well recognized. However, the causes of death in a complete incidence cohort and mortality patterns over time compared with the general population are unknown. METHOD:All 2723 patients who presented for the first time with psychosis in three defined ...

journal_title：Psychological medicine

authors： Dutta R,Murray RM,Allardyce J,Jones PB,Boydell JE

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Patients with anorexia nervosa (AN) run a high risk of becoming chronically ill and of dying. In the acute phase of their illness they present with numerous physical and laboratory abnormalities. However, little is known about the long-term prognostic value of these findings or about the medical morbidity in...

journal_title：Psychological medicine

authors： Herzog W,Deter HC,Fiehn W,Petzold E

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:To date, magnetic resonance imaging (MRI) has made little impact on the diagnosis and monitoring of psychoses in individual patients. In this study, we used a support vector machine (SVM) whole-brain classification approach to predict future illness course at the individual level from MRI data obtained at th...

journal_title：Psychological medicine

authors： Mourao-Miranda J,Reinders AA,Rocha-Rego V,Lappin J,Rondina J,Morgan C,Morgan KD,Fearon P,Jones PB,Doody GA,Murray RM,Kapur S,Dazzan P

更新日期：2012-05-01 00:00:00

abstract：:To investigate the relationships between cardiovascular variables (SBP, DBP, and HR) and circulating natural killer (NK) cell numbers, 70 male volunteers were subjected to a rest condition (N = 30) or a stressful laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the numb...

journal_title：Psychological medicine

authors： Benschop RJ,Godaert GL,Geenen R,Brosschot JF,De Smet MB,Olff M,Heijnen CJ,Ballieux RE

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, but risk factors associated with cognitive deficits in euthymic BD are still poorly understood. We aimed to validate classification criteria for the identification of clinically significant cognitive...

journal_title：Psychological medicine

authors： Roux P,Etain B,Cannavo AS,Aubin V,Aouizerate B,Azorin JM,Bellivier F,Belzeaux R,Bougerol T,Cussac I,Courtet P,Kahn JP,Leboyer M,M'Bailara K,Payet MP,Olié E,FondaMental Advanced Centers of Expertise in Bipolar Disorders (F

更新日期：2019-02-01 00:00:00

abstract：:An attempt was made to identify background, sociodemographic and clinical variables which are associated with attempted suicide in depression. Within a sample of 308 depressed psychiatric inpatients, suicide attempters were younger than non-attempters and were identified by a pattern of chronic interpersonal maladjust...

journal_title：Psychological medicine

authors： Crook T,Raskin A,Davis D

更新日期：1975-11-01 00:00:00

abstract：:Patients suffering from manic-depressive psychosis, manic type (ICD 296.0), were treated with lithium carbonate and randomly allocated to two groups, one received digoxin and the other matching placebo for 7 days. Severity of mania was rated by psychiatrists on the Manic Rating Scale and Analogue Line on days 0 and 7 ...

journal_title：Psychological medicine

authors： Chambers CA,Smith AH,Naylor GJ

更新日期：1982-02-01 00:00:00

abstract：:Instruments designed to assess psychiatric disorders in people with learning difficulties (mental handicap) were critically reviewed from a psychometric perspective. Major trends were found in the assessment of psychopathology related to DSM-III and depressive disorders although research in other areas was patchy. Alt...

journal_title：Psychological medicine

authors： Sturmey P,Reed J,Corbett J

更新日期：1991-02-01 00:00:00

abstract：:Twenty-three acute psychotic patients who were drug free at the time of testing performed a motor task designed to elicit many errors. Normal subjects and many of the psychotic patients were able to correct these errors in the absence of visual feedback. The ability to make such corrections depends on the subject know...

journal_title：Psychological medicine

authors： Frith CD,Done DJ

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) is overrepresented in prison, making it imperative to identify a screening tool that can be quickly applied to efficiently detect the disorder. We explored the discrimination ability of a widely used ADHD screen, the Barkley Adult ADHD Rating Scale (BAARS-IV), ...

journal_title：Psychological medicine

authors： Young S,González RA,Mutch L,Mallet-Lambert I,O'Rourke L,Hickey N,Asherson P,Gudjonsson GH

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:We investigated whether schizophrenic subjects are impaired in non-routine behaviour because of the dysfunction of a general executive component labelled, in neuropsychological terms, the supervisory system. METHODS:A specific verbal sequencing test was designed for this purpose. Subjects had to perform seq...

journal_title：Psychological medicine

authors： Robert PH,Migneco V,Chaix I,Berthet L,Kazes M,Danion JM,Baudu C,Darcourt G

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Victims of war captivity sometimes suffer from complex post-traumatic stress disorder (PTSD), a unique form of PTSD that entails various alterations in personality. These alterations may involve changes in attachment orientation. METHOD:The sample comprised two groups of veterans from the 1973 Yom Kippur Wa...

journal_title：Psychological medicine

authors： Solomon Z,Dekel R,Mikulincer M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Previous work suggests that individuals with schizophrenia display an altered homovanillic acid (HVA) response to metabolic stress. The present study replicated and extended this paradigm, including individuals with elevated genetic risk for schizophrenia. METHOD:Patients with psychosis (n = 50), non-psycho...

journal_title：Psychological medicine

authors： Marcelis M,Cavalier E,Gielen J,Delespaul P,Van Os J

更新日期：2004-08-01 00:00:00

abstract：:The present study examined sensitivity to noise in subjects with Type A and Type B behaviour patterns as a function of the type of task being performed. Twenty Type A and 20 Type B subjects, selected by means of Bortner's scale (French version), were exposed to steadily increasing noise levels (68-110 dBA) while perfo...

journal_title：Psychological medicine

authors： Moch A

更新日期：1984-08-01 00:00:00

abstract：:Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...

journal_title：Psychological medicine

authors： Mindham RH,Marsden CD,Parkes JD

更新日期：1976-02-01 00:00:00