Congenital polycystic tumor of the atrioventricular node (endodermal heterotopia, mesothelioma): a histogenetic appraisal with evidence for its endodermal origin.

abstract：:An unusual case of acute respiratory obstruction caused by multicentric granular cell tumors of the laryngotracheobronchial tree is presented. The patient also had granular cell tumors in the tongue, vulva, and chest wall. Multiplicity of the lesions in the left lung and recurrent episodes of intercurrent pulmonary in...

journal_title：Human pathology

authors： Majmudar B,Thomas J,Gorelkin L,Symbas PN

更新日期：1981-03-01 00:00:00

abstract：:We describe a case of simultaneous nodular sclerosing Hodgkin's disease and a granulocytic sarcoma in a cervical lymph node without any previous therapy. The condition evolved into acute myelogenous leukemia approximately 8 months after the initial diagnosis of the granulocytic sarcoma. The unexpected presence of a gr...

journal_title：Human pathology

authors： Suh YK,Shin SS,Koo CH

更新日期：1996-10-01 00:00:00

abstract：:The previously unreported association of granulomatous gastritis and mononeuritis multiplex occurring in the setting of a vasculitic syndrome is described. The two conditions are considered to be associated and to be immune mediated. The previously accepted concept of isolated granulomatous gastritis is disputed. ...

journal_title：Human pathology

authors： O'Donovan C,Murray J,Staunton H,Doyle JS,Leader M

更新日期：1991-10-01 00:00:00

abstract：:Cancer cells show a higher rate of anaerobic respiration than normal cells. The exact mechanisms for this higher glycolysis rate in cancer cells remain to be elucidated. The results of recent studies have indicated that p53, the most commonly mutated tumor suppressor gene, may have important functions in the regulatio...

journal_title：Human pathology

authors： Won KY,Lim SJ,Kim GY,Kim YW,Han SA,Song JY,Lee DK

更新日期：2012-02-01 00:00:00

abstract：:Pulmonary vein stenosis (PVS) is a rare disorder. Accurate diagnosis often requires anatomical examination. We report four children with pulmonary vein stenosis. Autopsy showed bilateral lesions in two patients who were thought clinically to have unilateral disease. A diagnosis of PVS was made at autopsy in the third ...

journal_title：Human pathology

authors： Sun CC,Doyle T,Ringel RE

更新日期：1995-08-01 00:00:00

abstract：:Digitization of histologic slides is associated with many advantages, and its use in routine diagnosis holds great promise. Nevertheless, few articles evaluate virtual microscopy in routine settings. This study is an evaluation of the validity and diagnostic performance of virtual microscopy in routine histologic diag...

journal_title：Human pathology

authors： Nielsen PS,Lindebjerg J,Rasmussen J,Starklint H,Waldstrøm M,Nielsen B

更新日期：2010-12-01 00:00:00

abstract：:Cell growth in the normal prostate is regulated by a delicate balance between cell death and cell proliferation (ie, apoptotic v proliferative activity). Disruption of the molecular mechanisms that regulate these two processes may underline the abnormal growth of the gland leading to benign prostatic hyperplasia (BPH)...

journal_title：Human pathology

authors： Kyprianou N,Tu H,Jacobs SC

更新日期：1996-07-01 00:00:00

abstract：:Overexpression of mitotic arrest deficient 2 (MAD2) and/or cell division cycle 20 (CDC20) in the spindle assembly checkpoint leads to chromosomal instability and aneuploidy. Cell-in-cell (CIC) structures are formed by the process where cancer or immune cells are internalized into adjacent host cancer cells. Here, we i...

journal_title：Human pathology

authors： Kim Y,Choi JW,Lee JH,Kim YS

更新日期：2019-03-01 00:00:00

abstract：:Clusterin has been reported to play a significant role in tumorigenesis, and its overexpression occurs in various human malignancies. We examine the clusterin overexpression in human hepatocellular carcinoma (HCC) and verify its clinical usefulness as a candidate biomarker by clinicopathologic and survival analysis. W...

journal_title：Human pathology

authors： Kang YK,Hong SW,Lee H,Kim WH

更新日期：2004-11-01 00:00:00

abstract：:A case of apocrine carcinoma of the breast with psammoma bodies is described in a 69 year old man. The report emphasizes the rarity of this lesion and supports currently held beliefs about the formation of psammoma bodies. ...

journal_title：Human pathology

authors： Bryant J

更新日期：1981-08-01 00:00:00

abstract：:Clear cell renal cell carcinoma is a complex disease with only partial response to therapy and scarce reliable clinical parameters indicative of progression and survival. Fibroblast activation protein expression has been correlated with prognosis in several malignancies but never in renal cancer. We aim to analyze the...

journal_title：Human pathology

authors： López JI,Errarte P,Erramuzpe A,Guarch R,Cortés JM,Angulo JC,Pulido R,Irazusta J,Llarena R,Larrinaga G

更新日期：2016-08-01 00:00:00

abstract：:Fifty-three pure mucinous carcinomas of breast were studied, with long-term follow-up evaluation (average, 15 years) for 37. The mean age of the patients was 63 years. Long-term survival (Kaplan-Meier method) was 68 per cent, excluding non-tumor-related deaths. Median survival for the patients with fatal carcinomas wa...

journal_title：Human pathology

authors： Clayton F

更新日期：1986-01-01 00:00:00

abstract：:We investigated whether histological chorioamnionitis (HCA) is a risk factor predisposing to leukemoid reaction (LR) and whether LR is associated with the preterm parturition syndrome and the systemic fetal inflammation response syndrome. A prospective histological study on placentas was performed in preterm infants (...

journal_title：Human pathology

authors： Zanardo V,Vedovato S,Trevisanuto DD,Suppiej A,Cosmi E,Fais GF,Chiarelli S

更新日期：2006-01-01 00:00:00

abstract：:Autopsy rates continue to decline despite abundant evidence of the autopsy's value. Such an extraordinary contradiction requires that we look beyond issues of education to consider our basic moral and political commitments; to consider, in other words, the kind of society in which we live, and the kind of people we ar...

journal_title：Human pathology

authors： Vance RP

更新日期：1990-02-01 00:00:00

abstract：:Abnormalities of the cell cycle are present in all neoplasms. Cyclin E, which regulates the G1/S phase transition of the cell cycle, plays an important role in many different cancers. To further investigate the role of cyclin E in invasive breast ductal carcinomas in South African women, representative sections from 1...

journal_title：Human pathology

authors： Donnellan R,Kleinschmidt I,Chetty R

更新日期：2001-01-01 00:00:00

abstract：:Villin (V) is a glycoprotein of microvilli associated with rootlet formation. Most colonic adenocarcinomas have a V positive (+), cytokeratin (CK) 20 (+), CK7-negative (-) immunophenotype; most lung adenocarcinomas have a CK20(-), CK7(+) immunophenotype. The reports of villin immunoreactivity in lung adenocarcinoma ra...

journal_title：Human pathology

authors： Tan J,Sidhu G,Greco MA,Ballard H,Wieczorek R

更新日期：1998-04-01 00:00:00

abstract：:A 48-year-old man with a history of recurrent urolithiasis and chronic renal failure underwent a nephrectomy for a renal mass. At surgery the mass proved to be a calculus impacted in a dilated calyx. Gross examination of the kidney revealed chalky white deposits in the deep medulla and papillary tips. Histologic exami...

journal_title：Human pathology

authors： Gelb AB,Fye KH,Tischfield JA,Sahota AS,Sparks JW,Hancock DC,Sibley RK

更新日期：1992-09-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumor is a malignant tumor showing nerve sheath differentiation. Approximately one-half of malignant peripheral nerve sheath tumors arise from a benign peripheral nerve sheath tumor, which is commonly a neurofibroma in patients with neurofibromatosis type 1. Malignant peripheral nerve...

journal_title：Human pathology

authors： Endo M,Yamamoto H,Harimaya K,Kohashi K,Ishii T,Setsu N,Iwamoto Y,Oda Y

更新日期：2013-12-01 00:00:00

abstract：:Mixed epithelial and stromal tumor of the kidney is a recently recognized neoplasm that occurs almost exclusively in perimenopausal women. Because it frequently contains areas of smooth muscle in which epithelial structures are embedded, some have concluded that it is the adult form of congenital mesoblastic nephroma....

journal_title：Human pathology

authors： Pierson CR,Schober MS,Wallis T,Sarkar FH,Sorensen PH,Eble JN,Srigley JR,Jones EC,Grignon DJ,Adsay V

更新日期：2001-05-01 00:00:00

abstract：:The clinical, pathologic, and immunologic features in nine cases of non-Hodgkin's lymphoma of the multilobated B-cell type are described. Clinical and phenotypic heterogeneity was observed in these B-cell neoplasms. A probable follicular center cell derivation for these cytologically unusual B-cell lymphomas is suppor...

journal_title：Human pathology

authors： O'Hara CJ,Said JW,Pinkus GS

更新日期：1986-06-01 00:00:00

abstract：:The current World Health Organization classification considers myelodysplastic syndrome with isolated del(5q) a distinct entity owing to its characteristic clinical and pathologic features. Recently, several studies have examined survival, leukemic transformation, and various prognostic factors in these patients. Howe...

journal_title：Human pathology

authors： Geyer JT,Verma S,Mathew S,Wang YL,Racchumi J,Espinal-Witter R,Subramaniyam S,Knowles DM,Orazi A

更新日期：2013-03-01 00:00:00

abstract：:We examined the effect of lateral spatial resolution and reader specialty on the accuracy of detection of breast cancer. The motivation for this pilot study was the need to acquire and display very large data sets in whole-specimen 3D digital breast histopathology imaging. The ultimate goal is to determine the minimum...

journal_title：Human pathology

authors： Clarke GM,Zubovits JT,Katic M,Peressotti C,Yaffe MJ

更新日期：2007-12-01 00:00:00

abstract：:Telomerase, the enzyme that stabilizes telomere length, is reactivated with almost all cancer types, and it may be necessary for unlimited cell proliferation. Assessment of malignancy in ordinary meningiomas is inconclusive because no clear-cut correlation exists between aggressive clinical behavior and histological f...

journal_title：Human pathology

authors： Langford LA,Piatyszek MA,Xu R,Schold SC Jr,Wright WE,Shay JW

更新日期：1997-04-01 00:00:00

abstract：:Strategies for cost containment in the clinical laboratory have been proposed and some are being tested. An approach is described and illustrated in this article for estimating the size of a cost reduction that might be observed in response to hypothetical changes in the utilization of the clinical laboratory. The var...

journal_title：Human pathology

authors： Finkelstein SN

更新日期：1980-09-01 00:00:00

abstract：:Tumor cells frequently evade apoptosis triggered by cellular stress via aberrant regulation of the BCL-2 family members, which are key players in regulating cell death under physiological and pathological situations. Previously, we have identified a novel BH3-only protein of the BCL-2 family, BLM-s (BCL-2-like molecul...

journal_title：Human pathology

authors： Tsai MS,Hsieh MS,Huang HY,Huang PH

更新日期：2019-02-01 00:00:00

abstract：:Graduate training is one of the most important activities in which we engage. Through PhD training programs in pathology, we continually renew the intellectual vigor of our discipline and assure its position as a vibrant force in the life sciences. To focus on this important issue, the Education Committee of the Ameri...

journal_title：Human pathology

authors： Kemp JD,Bowser R,American Society for Investigative Pathology workshop.

更新日期：2004-07-01 00:00:00

abstract：:Although early-stage cervical cancer can be treated by surgery, distant metastases can be life threatening. It has been a challenge to identify reliable biomarkers as indicators of metastasis or poor prognosis. We investigated the prognostic impact of vimentin, E-cadherin, and β-catenin expression measured by immunohi...

journal_title：Human pathology

authors： Cheng Y,Zhou Y,Jiang W,Yang X,Zhu J,Feng D,Wei Y,Li M,Yao F,Hu W,Xiao W,Ling B

更新日期：2012-08-01 00:00:00

abstract：:Glucose transporter (GLUT)-1 is expressed in malignant tumors and correlated with poor outcome in several cancers. Biliary intraepithelial neoplasia (BilIN) is considered to be a precursor or a noninvasive lesion of invasive cholangiocarcinoma. We examined GLUT-1 and GLUT-2 expression in 149 intrahepatic cholangiocarc...

journal_title：Human pathology

authors： Kubo Y,Aishima S,Tanaka Y,Shindo K,Mizuuchi Y,Abe K,Shirabe K,Maehara Y,Honda H,Oda Y

更新日期：2014-08-01 00:00:00

abstract：:Bcl-2 and bcl-xL are proteins known to inhibit cell death (apoptosis). Expression of these proteins in gangliogliomas has not been extensively examined. This study retrospectively evaluates bcl-2 and bcl-x immunostaining in paraffin-embedded materials in gangliogliomas. Twenty-nine gangliogliomas in 17 males and 12 fe...

journal_title：Human pathology

authors： Prayson RA

更新日期：1999-06-01 00:00:00

abstract：:To elucidate the role of Epstein-Barr virus (EBV) in salivary gland carcinomas, 56 cases of carcinomas of major salivary glands were investigated. These included 14 mucoepidermoid carcinomas, 13 adenoid cystic carcinomas, seven malignant mixed tumors, four adenocarcinomas, four salivary duct carcinomas, two acinic cel...

journal_title：Human pathology

authors： Tsai CC,Chen CL,Hsu HC

更新日期：1996-03-01 00:00:00