Comparative results of 327 chemical carcinogenicity studies.

Abstract:

:The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of carcinogenicity in these experiments. This compilation of results from NCI/NTP carcinogenicity experiments provides a large database that can be used to study structure-activity correlations, interspecies concordance, and associations between laboratory animal carcinogenicity and other toxicological effects.

authors

Haseman JK,Huff JE,Zeiger E,McConnell EE

doi

10.1289/ehp.8774229

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

229-35

eissn

0091-6765

issn

1552-9924

journal_volume

74

pub_type

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