Corticosterone and prolactin responses to predictable and unpredictable novelty stress in rats.

Abstract:

:Prolactin along with corticosterone is a stress responsive hormone. The present study examined the effect of predictable and unpredictable psychological stress on corticosterone and prolactin secretion. Repeated unpredictable exposure to the novelty cage produced a more substantial increase in the level of corticosterone than predictable exposure to the same novelty apparatus. In contrast, predictable novelty stress induced a more substantial elevation in prolactin levels than unpredictable stress. Furthermore, it was observed that both corticosterone and prolactin returned to control levels 30 minutes after the fifth exposure to the novelty cage. It was concluded that the pattern of exposure to novelty is an important paradigm which effects the magnitude of hormonal responding. An important relationship between corticosterone release and prolactin secretion is also indicated.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Muir JL,Pfister HP

doi

10.1016/0031-9384(86)90234-9

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

285-8

issue

2

eissn

0031-9384

issn

1873-507X

pii

0031-9384(86)90234-9

journal_volume

37

pub_type

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