Role of the area postrema in radiation-induced taste aversion learning and emesis in cats.

Abstract:

:The role of the area postrema in radiation-induced emesis and taste aversion learning and the relationship between these behaviors were studied in cats. The potential involvement of neural factors which might be independent of the area postrema was minimized by using low levels of ionizing radiation (100 rads at a dose rate of 40 rads/min) to elicit a taste aversion, and by using body-only exposures (4500 and 6000 rads at 450 rads/min) to produce emesis. Lesions of the area postrema disrupted both taste aversion learning and emesis following irradiation. These results, which indicate that the area postrema is involved in the mediation of both radiation-induced emesis and taste aversion learning in cats under these experimental conditions, are interpreted as being consistent with the hypotheses that similar mechanisms mediate both responses to exposure to ionizing radiation, and that the taste aversion learning paradigm can therefore serve as a model system for studying radiation-induced emesis.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Rabin BM,Hunt WA,Chedester AL,Lee J

doi

10.1016/0031-9384(86)90189-7

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

815-8

issue

5

eissn

0031-9384

issn

1873-507X

pii

0031-9384(86)90189-7

journal_volume

37

pub_type

杂志文章
  • Protective effect of n-butanol extract from Alpinia oxyphylla on learning and memory impairments.

    abstract::Alzheimer's disease (AD) is one of the major neurological diseases of the elderly. How to safely and effectively remove the toxic Aβ42 peptide through blood-brain barrier (BBB) is considered to be an effective method for the prevention and treatment of AD. The compounds whose molecule weight is less than 400 Da and th...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.11.016

    authors: Shi SH,Zhao X,Liu AJ,Liu B,Li H,Wu B,Bi KS,Jia Y

    更新日期:2015-02-01 00:00:00

  • Decelerated and linear eaters: effect of eating rate on food intake and satiety.

    abstract::Women were divided into those eating at a decelerated or linear rate. Eating rate was then experimentally increased or decreased by asking the women to adapt their rate of eating to curves presented on a computer screen and the effect on food intake and satiety was studied. Decelerated eaters were unable to eat at an ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2008.10.011

    authors: Zandian M,Ioakimidis I,Bergh C,Brodin U,Södersten P

    更新日期:2009-02-16 00:00:00

  • Morphine and dextrorphan lose antinociceptive activity but exhibit an antispastic action in chronic spinal rats.

    abstract::Within 3-4 weeks after spinal transection, morphine-induced antinociception, assessed with the tail flick reflex in rats, is profoundly reduced. The cause of this decrement is unknown. The present studies were conducted to determine whether this phenomenon reflects a general loss in opiate activity or a selective decl...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00240-0

    authors: Advokat C,Mosser H,Hutchinson K

    更新日期:1997-10-01 00:00:00

  • Alcohol alliesthesia: food restriction increases the palatability of alcohol through a corticosterone-dependent mechanism.

    abstract::The present article analyzed the dramatic increase in alcohol ingestion that is known to occur in laboratory rats subjected to food restriction. In the first experiment, we wished to know when during the day food restricted animals consume the "extra" alcohol ration. Determinations of ethanol drinking at 3-h intervals...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00078-5

    authors: Söderpalm AH,Hansen S

    更新日期:1999-09-01 00:00:00

  • Naloxone-sensitive potentiation at granule cell synapses in the ventral dentate gyrus and stress ulcers.

    abstract::Continuous perfusion of the granule cells in the ventral dentate gyrus with naloxone blocked the long-term potentiation (LTP) induced by high-frequency electrical stimulation of the posterolateral amygdala in freely-moving rats. This treatment also aggravated the stomach ulceration produced by cold restraint. LTP, on ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90121-h

    authors: Henke PG

    更新日期:1992-04-01 00:00:00

  • Combined effects of Depo-Provera and Fadrozole on the sexual behavior of intact male cynomolgus monkeys (Macaca fascicularis).

    abstract::Our previous studies showed that treating castrated, testosterone-treated male cynomolgus monkeys with Depo-Provera (medroxyprogesterone acetate, MPA) decreased ejaculatory performance and also measures of male sexual motivation by about 40%. Similarly, treating castrated, testosterone-treated males with the nonsteroi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90224-0

    authors: Zumpe D,Michael RP

    更新日期:1994-10-01 00:00:00

  • Influences of water deprivation and fasting on hypothalamic, pituitary and plasma opioid peptides and prolactin in rats.

    abstract::To study the physiological roles of endogenous opioid peptides in drinking and feeding behaviors, the effects of water deprivation and fasting on plasma immunoreactive (IR) beta-endorphin (beta-end), IR-Antidiuretic hormone (ADH) and IR-Prolactin (Prl), pituitary IR-beta-end and IR-methionine-enkephalin (IR-Met-enk) a...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90293-3

    authors: Takahashi H,Motomatsu T,Nobunaga M

    更新日期:1986-01-01 00:00:00

  • The temporal dynamics of reversal learning: P3 amplitude predicts valence-specific behavioral adjustment.

    abstract::Adapting behavior to dynamic stimulus-reward contingences is a core feature of reversal learning and a capacity thought to be critical to socio-emotional behavior. Impairment in reversal learning has been linked to multiple psychiatric outcomes, including depression, Parkinson's disorder, and substance abuse. A recent...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.03.034

    authors: Donaldson KR,Ait Oumeziane B,Hélie S,Foti D

    更新日期:2016-07-01 00:00:00

  • Decreased feeding associated with acute hypoxia in rats.

    abstract::Rats obtained less food than normal on a cyclic-ratio schedule during brief, 1-hr exposure to either moderate hypobaric hypoxia (BP = 435 Torr, PO2 approximately equal to 91 Torr) or to hypoxic hypoxia (BP = 750 Torr, PO2, approximately equal to 90 Torr), but not during hypobaric exposure with 36.5% oxygen (BP = 435 T...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90266-9

    authors: Ettinger RH,Staddon JE

    更新日期:1982-09-01 00:00:00

  • Decreased dominance in a limited access test but normal maternal behavior in micrencephalic rats.

    abstract::Micrencephalic offspring produced by gestational treatment with the antimitotic compound/methylazoxymethanol acetate (MAM) are remarkable for substantial preservation of function concurrent with severe neural stunting. Altered behaviors in these micrencephalics, including light shyness and response perseveration, are ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)00154-b

    authors: Ferguson SA,Arrowood JW,Schultetus RS,Holson RR

    更新日期:1995-11-01 00:00:00

  • Sensitivity of salivary hydrogen sulfide to psychological stress and its association with exhaled nitric oxide and affect.

    abstract:BACKGROUND:Hydrogen sulfide (H2S) is the third gasotransmitter recently discovered after nitric oxide (NO) and carbon monoxide. Both NO and H2S are involved in multiple physiological functions. Whereas NO has been shown to vary with psychological stress, the influence of stress on H2S and the relationship between H2S a...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.05.023

    authors: Kroll JL,Werchan CA,Reeves AG,Bruemmer KJ,Lippert AR,Ritz T

    更新日期:2017-10-01 00:00:00

  • Assessing pain threshold in the rat: changes with estrus and time of day.

    abstract::Pain threshold was determined in female rats using the tail flick test. Latency to respond depended on the locus of the tail heated, with the most distal sites resulting in the shortest response times (Experiment 1). Tail flick latency also varied according to the time of day, with shorter response times recorded arou...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90040-x

    authors: Martínez-Gómez M,Cruz Y,Salas M,Hudson R,Pacheco P

    更新日期:1994-04-01 00:00:00

  • Taste performance in Sjogren's syndrome.

    abstract::Sjogren's Syndrome (SS) patients have impaired salivary gland function and an elevated frequency of oral complaints. The taste complaints are thought to be due to sensory deficits that arise in the absence of sufficient saliva to maintain taste receptors. We assessed the subjective complaints, salivary production and ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)00211-m

    authors: Weiffenbach JM,Schwartz LK,Atkinson JC,Fox PC

    更新日期:1995-01-01 00:00:00

  • Interactions of testosterone with the olfactory system in the display of mounting behavior in the female rat.

    abstract::Adult ovariectomized female rats received a testosterone propionate (TP) silastic implant (day 0) and were subsequently tested for mounting behavior. The number of females displaying mounting behavior increased from day 2 (0%) to day 14 (94%) following testosterone implantation. Olfactory bulbectomy (OB) performed on ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90428-q

    authors: Boehm N,Lazarus C,Aron C

    更新日期:1991-11-01 00:00:00

  • Ileal brake: a sensible food target for appetite control. A review.

    abstract::With the rising prevalence of obesity and related health problems increases, there is increased interest in the gastrointestinal system as a possible target for pharmacological or food-based approaches to weight management. Recent studies have shown that under normal physiological situations undigested nutrients can r...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2008.07.018

    authors: Maljaars PW,Peters HP,Mela DJ,Masclee AA

    更新日期:2008-10-20 00:00:00

  • Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine.

    abstract::Roux-en-Y gastric bypass (RYGB) surgery might modify the gut microbiota composition differently in the three distinct anatomical sections of the small intestine compared to sham surgery. We showed that RYGB induced changes in the microbiota of the alimentary limb and the common channel resembling those seen after preb...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.06.008

    authors: Osto M,Abegg K,Bueter M,le Roux CW,Cani PD,Lutz TA

    更新日期:2013-07-02 00:00:00

  • Taste detection and discrimination performance of rats following selective desalivation.

    abstract::Taste sensitivity and responsivity, two-tastant and taste-mixture discrimination performance, and taste preferences were examined prior to and after the selective desalivation of 48 male Long-Evans rats. Altered preference behavior was observed in rats after removal of the major salivary glands, as well as after remov...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90200-n

    authors: Brosvic GM,Hoey NE

    更新日期:1990-11-01 00:00:00

  • Level searching: a new assay of sexual motivation in the male rat.

    abstract::Mendelson and Gorzalka recently described a bilevel chamber for the evaluation of rodent sexual behavior. In initial studies it was observed that during 5 min adaptation periods prior to the introduction of a sexually receptive female rat, male rats with prior sexual experience in these chambers would move from level ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90136-4

    authors: Mendelson SD,Pfaus JG

    更新日期:1989-02-01 00:00:00

  • Naloxone decreases consumption of liquid and solid sucrose in vagotomized rats.

    abstract::Intraperitoneal injections of the opiate antagonist naloxone decreased food intake in both vagotomized and sham-vagotomized rats. Consumption of liquid and solid sucrose, which were used in order to equate baseline intake, was equally suppressed in both groups under food-deprivation and appetitively-motivated conditio...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90345-6

    authors: Clarkson DB,King BM,Hemmer RC,Olson GA,Kastin AJ,Olson RD

    更新日期:1982-11-01 00:00:00

  • Modulatory effect of 17-β estradiol on performance of ovariectomized rats on the Shock-Probe test.

    abstract::17-β estradiol (E2) has been shown to modulate fear conditioning by influencing freezing behavior following re-exposure to either the conditioning context or a cue associated with shock. Fear-related behaviors other than freezing may be influenced differently by E2 replacement. Accordingly, the present study examined ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.04.030

    authors: Gervais NJ,Jacob S,Brake WG,Mumby DG

    更新日期:2014-05-28 00:00:00

  • Evolutionary insights into the regulation of courtship behavior in male amphibians and reptiles.

    abstract::Comparative studies of species differences and similarities in the regulation of courtship behavior afford an understanding of evolutionary pressures and constraints shaping reproductive processes and the relative contributions of hormonal, genetic, and ecological factors. Here, we review species differences and simil...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2004.08.021

    authors: Woolley SC,Sakata JT,Crews D

    更新日期:2004-11-15 00:00:00

  • Effectiveness of an applied high intensity interval training as a specific operative training.

    abstract::The psychophysiological response due to stress of soldiers in actual combat operations have been determined by recent researchers, but there is a lack of knowledge about the most effective training methodologies to prepare these population for these new psychophysiological and tactical requirements. The aim of this st...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.01.009

    authors: Curiel-Regueros A,Fernández-Lucas J,Clemente-Suárez VJ

    更新日期:2019-03-15 00:00:00

  • Further evidence that stress hyperthermia is a fever.

    abstract::Exposure of rats to an open-field results in a rapid rise in body temperature. Fifty-four percent of this rise in body temperature was blocked by intracerebroventricular administration of the antipyretic drug sodium salicylate. Intraperitoneal administration of indomethacin, a potent blocker of prostaglandin productio...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90263-0

    authors: Kluger MJ,O'Reilly B,Shope TR,Vander AJ

    更新日期:1987-01-01 00:00:00

  • Calorie-restricted mice that gorge show less ability to compensate for reduced energy intake.

    abstract::Caloric restriction in mice can trigger gorging behaviour, which is characterized by periods of excessive food ingestion in a short time. Animals that gorge are thought to have a reduced metabolism compared to those that nibble their food over a longer period and might therefore be more able to compensate for reduced ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.07.005

    authors: Hambly C,Simpson CA,McIntosh S,Duncan JS,Dalgleish GD,Speakman JR

    更新日期:2007-12-05 00:00:00

  • Hypercholesterolemic diet applied to rat dams protects their offspring against cognitive deficits. Simulated neonatal anoxia model.

    abstract::There is accumulating data suggesting a neuroprotective activity of cholesterol, especially in stroke and Alzheimer's disease (AD). In the present study, a protective activity of this lipid in simulated neonatal anoxia was investigated. Rats were subjected to high cholesterol by feeding their dams with a diet enriched...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2004.06.009

    authors: Bohr I

    更新日期:2004-09-30 00:00:00

  • The effects of experimentally manipulated social status on acute eating behavior: A randomized, crossover pilot study.

    abstract::Both subjective and objectively measured social status has been associated with multiple health outcomes, including weight status, but the mechanism for this relationship remains unclear. Experimental studies may help identify the causal mechanisms underlying low social standing as a pathway for obesity. Our objective...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2016.04.024

    authors: Cardel MI,Johnson SL,Beck J,Dhurandhar E,Keita AD,Tomczik AC,Pavela G,Huo T,Janicke DM,Muller K,Piff PK,Peters JC,Hill JO,Allison DB

    更新日期:2016-08-01 00:00:00

  • Effects of potassium-aspartate salt administration on glycogen use in the rat during a swimming stress.

    abstract::The ergogenic effect of aspartate salts on performance during prolonged exercise is still controversial. Potential mechanisms of the suggested ergogenic effect of aspartate on exercise performance are a sparing of muscle glycogen stores or its faster resynthesis during exercise. The purpose of this study was to determ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90036-f

    authors: Trudeau F,Murphy R

    更新日期:1993-07-01 00:00:00

  • The rate of weight loss does not affect resting energy expenditure and appetite sensations differently in women living with overweight and obesity.

    abstract:BACKGROUND:Evidence of metabolic adaptations following weight loss is available in the literature. However, the impact of different degrees of caloric restriction on a comprehensive panel including energy expenditure (EE) and intake (EI), appetite, palatability and olfactory performance remains to be investigated. Acco...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2018.11.032

    authors: Hintze LJ,Goldfield G,Seguin R,Damphousse A,Riopel A,Doucet É

    更新日期:2019-02-01 00:00:00

  • Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome.

    abstract::Post-exertional exacerbation of symptoms is one of the major characteristics of chronic fatigue syndrome (CFS). In this study, we evaluated the hypothesis that disturbances in circadian chronobiological regulation may play a role in generating this phenomenon. We recorded physical activity for 6-day periods in 16 wome...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(02)00808-9

    authors: Ohashi K,Yamamoto Y,Natelson BH

    更新日期:2002-09-01 00:00:00

  • The stress of intruding: reduction by chlordiazepoxide.

    abstract::Rats placed as intruders in a long-established colony showed significant elevations of plasma corticosterone after 10-20 minutes of intruding. This rise was prevented by 5 days pretreatment with chlordiazepoxide (5 mg/kg). The rats resident in the colony had significantly higher basal corticosterone concentrations com...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(84)90152-5

    authors: File SE

    更新日期:1984-09-01 00:00:00