Noise in stenosis measurement using digital subtraction angiography.

Abstract:

:This paper examines statistical errors in the measurement of arterial stenoses by digital videodensitometry. Images of vessel phantoms were acquired using digital subtraction angiographic techniques with low concentrations of an iodine contrast medium and low levels of x-ray exposure. Effects of the spatial and temporal averaging of image information on signal-to-noise ratios in the stenosis measurement were of primary interest. The influences of iodine concentration, x-ray scatter, veiling glare, x-ray energy spectrum, x-ray exposure, and detective quantum efficiency of the system were also included in the theoretical analysis. The agreement between theoretical calculation and experimental measurement of a simulated vessel was verified using measured values of the imaging system parameters. With a 14.2 mg/ml iodine concentration, using 20 mR per image at the entrance to a 13-cm water phantom, and averaging over a 6-mm length of a vessel 6.2 mm in diameter, the standard deviation in a measurement of a vessel's relative cross-sectional area was about 0.05. The extension of these results to practical applications in vivo is discussed.

journal_name

Med Phys

journal_title

Medical physics

authors

Wright GA,Taylor KW,Rowlands JA

doi

10.1118/1.595652

subject

Has Abstract

pub_date

1985-11-01 00:00:00

pages

705-12

issue

6

eissn

0094-2405

issn

2473-4209

journal_volume

12

pub_type

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