4D rotational x-ray imaging of wrist joint dynamic motion.

Abstract:

:Current methods for imaging joint motion are limited to either two-dimensional (2D) video fluoroscopy, or to animated motions from a series of static three-dimensional (3D) images. 3D movement patterns can be detected from biplane fluoroscopy images matched with computed tomography images. This involves several x-ray modalities and sophisticated 2D to 3D matching for the complex wrist joint. We present a method for the acquisition of dynamic 3D images of a moving joint. In our method a 3D-rotational x-ray (3D-RX) system is used to image a cyclically moving joint. The cyclic motion is synchronized to the x-ray acquisition to yield multiple sets of projection images, which are reconstructed to a series of time resolved 3D images, i.e., four-dimensional rotational x ray (4D-RX). To investigate the obtained image quality parameters the full width at half maximum (FWHM) of the point spread function (PSF) via the edge spread function and the contrast to noise ratio between air and phantom were determined on reconstructions of a bullet and rod phantom, using 4D-RX as well as stationary 3D-RX images. The CNR in volume reconstructions based on 251 projection images in the static situation and on 41 and 34 projection images of a moving phantom were 6.9, 3.0, and 2.9, respectively. The average FWHM of the PSF of these same images was, respectively, 1.1, 1.7, and 2.2 mm orthogonal to the motion and parallel to direction of motion 0.6, 0.7, and 1.0 mm. The main deterioration of 4D-RX images compared to 3D-RX images is due to the low number of projection images used and not to the motion of the object. Using 41 projection images seems the best setting for the current system. Experiments on a postmortem wrist show the feasibility of the method for imaging 3D dynamic joint motion. We expect that 4D-RX will pave the way to improved assessment of joint disorders by detection of 3D dynamic motion patterns in joints.

journal_name

Med Phys

journal_title

Medical physics

authors

Carelsen B,Bakker NH,Strackee SD,Boon SN,Maas M,Sabczynski J,Grimbergen CA,Streekstra GJ

doi

10.1118/1.2000647

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

2771-6

issue

9

eissn

0094-2405

issn

2473-4209

journal_volume

32

pub_type

杂志文章
  • Evaluation of the 4D RADPOS dosimetry system for dose and position quality assurance of CyberKnife.

    abstract:PURPOSE:The Synchrony respiratory motion tracking of the CyberKnife system purports to provide real-time tumor motion compensation during robotic radiosurgery. Such a complex delivery system requires thorough quality assurance. In this work, RADPOS applicability as a dose and position quality assurance tool for CyberKn...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13102

    authors: Marants R,Vandervoort E,Cygler JE

    更新日期:2018-07-25 00:00:00

  • X-ray diffraction computed tomography.

    abstract::Coherent scattering of x-ray photons leads to the phenomenon of x-ray diffraction, which is widely used for determining atomic structure in materials science. A technique [x-ray diffraction computed tomography (CT)] is described, analogous to conventional CT, in which the x-ray diffraction properties of a stack of two...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596063

    authors: Harding G,Kosanetzky J,Neitzel U

    更新日期:1987-07-01 00:00:00

  • SU-E-T-96: Energy Dependence of the New GafChromic- EBT3 Film's Dose Response-Curve.

    abstract:PURPOSE:To study and compare the dose response curves of the new GafChromic EBT3 film for megavoltage and kilovoltage x-ray beams, with different spatial resolution. METHODS:Two sets of EBT3 films (lot#A101711-02) were exposed to each x-ray beam (6MV, 15MV and 50kV) at 8 dose values (50-3200cGy). The megavoltage beams...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735153

    authors: Chiu-Tsao S,Massillon-Jl G,Domingo-Muñoz I,Chan M

    更新日期:2012-06-01 00:00:00

  • Creating optimal code for GPU-accelerated CT reconstruction using ant colony optimization.

    abstract:PURPOSE:CT reconstruction algorithms implemented on the GPU are highly sensitive to their implementation details and the hardware they run on. Fine-tuning an implementation for optimal performance can be a time consuming task and require many updates when the hardware changes. There are some techniques that do automati...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4773045

    authors: Papenhausen E,Zheng Z,Mueller K

    更新日期:2013-03-01 00:00:00

  • Robust experiment design for estimating myocardial beta adrenergic receptor concentration using PET.

    abstract::Myocardial beta adrenergic receptor (beta-AR) concentration can substantially decrease in congestive heart failure and significantly increase in chronic volume overload, such as in severe aortic valve regurgitation. Positron emission tomography (PET) with an appropriate ligand-receptor model can be used for noninvasiv...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2402585

    authors: Salinas C,Muzic RF Jr,Ernsberger P,Saidel GM

    更新日期:2007-01-01 00:00:00

  • Effects of tumor motion in GRID therapy.

    abstract::Clinical and biological evidence suggest that the success of GRID therapy in debulking large tumors depends on the high peak-to-valley contrast in the dose distribution. In this study, we show that the peaks and valleys can be significantly blurred out by respiration-induced tumor motion, possibly affecting the clinic...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2977538

    authors: Naqvi SA,Mohiuddin MM,Ha JK,Regine WF

    更新日期:2008-10-01 00:00:00

  • Stereomammography: evaluation of depth perception using a virtual 3D cursor.

    abstract::We are evaluating the usefulness of stereomammography in improving breast cancer diagnosis. One area that we are investigating is whether the improved depth perception associated with stereomammography might be significantly enhanced with the use of a virtual 3D cursor. A study was performed to evaluate the accuracy o...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.599008

    authors: Goodsitt MM,Chan HP,Hadjiiski L

    更新日期:2000-06-01 00:00:00

  • Performance of a high-sensitivity dedicated cardiac SPECT scanner for striatal uptake quantification in the brain based on analysis of projection data.

    abstract:PURPOSE:The authors have previously reported the advantages of high-sensitivity single-photon emission computed tomography (SPECT) systems for imaging structures located deep inside the brain. DaTscan (Isoflupane I-123) is a dopamine transporter (DaT) imaging agent that has shown potential for early detection of Parkin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4794488

    authors: Park MA,Moore SC,Müller SP,McQuaid SJ,Kijewski MF

    更新日期:2013-04-01 00:00:00

  • Noise, resolution, and sensitivity considerations in the design of a single-slice emission-transmission computed tomographic system.

    abstract::A prototype Emission-Transmission Computed Tomography (ETCT) system is being developed that will acquire single-slice x-ray transmission CT images simultaneously with single photon emission computed tomography (SPECT) images. This system will permit the correlation of anatomical information from x-ray CT with function...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596643

    authors: Liew SC,Hasegawa BH

    更新日期:1991-09-01 00:00:00

  • An investigation on the use of removal-diffusion theory for BNCT treatment planning: a method for determining proper removal-diffusion parameters.

    abstract::This paper outlines a method for determining proper removal-diffusion parameters to be used in removal-diffusion theory calculations for the purpose of BNCT treatment planning. Additionally, this paper demonstrates that, given the proper choice of removal-diffusion parameters, removal-diffusion theory may provide an a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1386424

    authors: Albertson BJ,Blue TE,Niemkiewicz J

    更新日期:2001-09-01 00:00:00

  • 4D DMLC leaf sequencing to minimize organ at risk dose in moving anatomy.

    abstract::The most favorable treatment for moving body anatomy should aim at utilizing organ motion to minimize the dose to sensitive structures without compromising the dose delivered to the target. The solution of the problem of appropriate intensity redistribution over different phases of body motion is achievable in dynamic...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.2804722

    authors: Papiez L,McMahon R,Timmerman R

    更新日期:2007-12-01 00:00:00

  • SU-E-T-144: Daily and Monthly Quality Assurance with TomoDose.

    abstract:PURPOSE:Examine the use of TomoDose for Tomotherapy quality assurance. METHODS:Baseline TomoDose profiles are acquired annually in accordance with TG-148. During monthly quality assurance, TomoDose is irradiated with a static beam and referenced to baseline. Differences between superimposed profiles are evaluated mont...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735202

    authors: Terrell J

    更新日期:2012-06-01 00:00:00

  • SU-E-T-476: GPU-Based Monte Carlo Radiotherapy Dose Calculation Using Phase- Space Sources.

    abstract:PURPOSE:To design an efficient method for utilizing phase-space source models in the GPU-based Monte Carlo (MC) dose calculation engine gDPM. METHODS:In GPU-based MC algorithms, particles are transported in parallel on different threads. Particles of different types and energies can require significantly different exe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735565

    authors: Townson R,Jia X,Zavgorodni S,Jiang S

    更新日期:2012-06-01 00:00:00

  • Quantitative cone-beam CT imaging in radiation therapy using planning CT as a prior: first patient studies.

    abstract:PURPOSE:Quantitative cone-beam CT (CBCT) imaging is on increasing demand for high-performance image guided radiation therapy (IGRT). However, the current CBCT has poor image qualities mainly due to scatter contamination. Its current clinical application is therefore limited to patient setup based on only bony structure...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3693050

    authors: Niu T,Al-Basheer A,Zhu L

    更新日期:2012-04-01 00:00:00

  • Vision 20/20: Positron emission tomography in radiation therapy planning, delivery, and monitoring.

    abstract::Positron emission tomography (PET) is increasingly considered as an effective imaging method to support several stages of radiation therapy. The combined usage of functional and morphological imaging in state-of-the-art PET/CT scanners is rapidly emerging to support the treatment planning process in terms of improved ...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.4935869

    authors: Parodi K

    更新日期:2015-12-01 00:00:00

  • Quantitative classification of breast tumors in digitized mammograms.

    abstract::The goal of this study was to develop a technique to distinguish benign and malignant breast lesions in secondarily digitized mammograms. A set of 51 mammograms (two views/patient) containing lesions of known pathology were evaluated using six different morphological descriptors: circularity, mu R/sigma R (where mu R ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597707

    authors: Pohlman S,Powell KA,Obuchowski NA,Chilcote WA,Grundfest-Broniatowski S

    更新日期:1996-08-01 00:00:00

  • A sparse orthogonal collimator for small animal intensity-modulated radiation therapy part I: Planning system development and commissioning.

    abstract:PURPOSE:To achieve more translatable preclinical research results, small animal irradiation needs to more closely simulate human radiotherapy. Although the clinical gold standard is intensity-modulated radiation therapy (IMRT), the direct translation of this method for small animals is impractical. In this study we des...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13872

    authors: Woods K,Nguyen D,Neph R,Ruan D,O'Connor D,Sheng K

    更新日期:2019-12-01 00:00:00

  • A novel approach to evaluate spatial resolution of MRI clinical images for optimization and standardization of breast screening protocols.

    abstract:PURPOSE:Stringent quality assurance is required in MRI breast screening to ensure that different scanners and imaging protocols reach similar diagnostic performance. The authors propose a methodology, based on power spectrum analysis (PSA), to evaluate spatial resolution in clinical images. To demonstrate this approach...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4966704

    authors: Borri M,Scurr ED,Richardson C,Usher M,Leach MO,Schmidt MA

    更新日期:2016-12-01 00:00:00

  • Vision 20/20: Magnetic resonance imaging-guided attenuation correction in PET/MRI: Challenges, solutions, and opportunities.

    abstract::Attenuation correction is an essential component of the long chain of data correction techniques required to achieve the full potential of quantitative positron emission tomography (PET) imaging. The development of combined PET/magnetic resonance imaging (MRI) systems mandated the widespread interest in developing nov...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.4941014

    authors: Mehranian A,Arabi H,Zaidi H

    更新日期:2016-03-01 00:00:00

  • Estimation of organ doses from kilovoltage cone-beam CT imaging used during radiotherapy patient position verification.

    abstract:PURPOSE:The purpose of this study was to develop a practical method for estimating organ doses from kilovoltage cone-beam CT (CBCT) that can be performed with readily available phantoms and dosimeters. The accuracy of organ dose estimates made using the ImPACT patient dose calculator was also evaluated. METHODS:A 100 ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3476459

    authors: Hyer DE,Hintenlang DE

    更新日期:2010-09-01 00:00:00

  • Penalized likelihood fluence optimization with evolutionary components for intensity modulated radiation therapy treatment planning.

    abstract::A novel iterative penalized likelihood algorithm with evolutionary components for the optimization of beamlet fluences for intensity modulated radiation therapy (IMRT) is presented. This algorithm is designed to be flexible in terms of the objective function and automatically escalates dose, as long as the objective f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1773631

    authors: Baydush AH,Marks LB,Das SK

    更新日期:2004-08-01 00:00:00

  • Measurements of the neutron yields from 7Li(p,n)7Be reaction (thick target) with incident energies from 1.885 to 2.0 MeV.

    abstract::Accelerator-based neutron source have been considered to be practical for boron neutron capture therapy (BNCT). Based on experience with a parameters of the Brookhaven National Laboratory BMRR reactor neutron source, which has been used in treatment experiments, the future accelerator-based neutron source for BNCT sho...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598299

    authors: Yu W,Yue G,Han X,Chen J,Tian B

    更新日期:1998-07-01 00:00:00

  • Experimental implementation of a joint statistical image reconstruction method for proton stopping power mapping from dual-energy CT data.

    abstract:PURPOSE:To experimentally commission a dual-energy CT (DECT) joint statistical image reconstruction (JSIR) method, which is built on a linear basis vector model (BVM) of material characterization, for proton stopping power ratio (SPR) estimation. METHODS:The JSIR-BVM method builds on the relationship between the energ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13287

    authors: Zhang S,Han D,Williamson JF,Zhao T,Politte DG,Whiting BR,O'Sullivan JA

    更新日期:2019-01-01 00:00:00

  • Poster - Thurs Eve-31: Clinical implementation and experience with EPID-based precision isocentre localization.

    abstract::Modern linear accelerators contain multiple isocentres, defined by the mechanical motions of gantry, collimator and table. Isocentre localization for these motions has been performed using film and manual evaluations which have difficulty in relating the individual motions. To address these limitations, we have develo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965950

    authors: Heaton R,Smale J,Norrlinger B,Wang Y,van Prooijen M,Islam M

    更新日期:2008-07-01 00:00:00

  • Gamma dose measurement in a d(80) + Be neutron beam.

    abstract::The gamma-ray dose component of a d(80) + Be neutron beam was measured with a 6Li-shielded Geiger-Mueller counter in a tissue-equivalent liquid phantom. The proportion of gamma-ray dose to total dose increased from 0.07 near the surface to 0.09 at 25 cm depth. Due to thermal neutron sensitivity, the G-M count rate inc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594571

    authors: Harrison GH,Cox CR

    更新日期:1979-05-01 00:00:00

  • Comparison of two methods for accurate measurement of modulation transfer functions of screen-film systems.

    abstract::The modulation transfer function (MTF) of a screen-film system can be measured by two methods, i.e., a slit method with Fourier transform on the line spread function and a square-wave response function (SWRF) method. However, it is still uncertain whether MTFs obtained by the two methods are identical. In this study, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597456

    authors: Morishita J,Doi K,Bollen R,Bunch PC,Hoeschen D,Sirand-rey G,Sukenobu Y

    更新日期:1995-02-01 00:00:00

  • Ultrafast treatment plan optimization for volumetric modulated arc therapy (VMAT).

    abstract:PURPOSE:To develop a novel aperture-based algorithm for volumetric modulated are therapy (VMAT) treatment plan optimization with high quality and high efficiency. METHODS:The VMAT optimization problem is formulated as a large-scale convex programming problem solved by a column generation approach. The authors consider...

    journal_title:Medical physics

    pub_type: 信件

    doi:10.1118/1.3491675

    authors: Men C,Romeijn HE,Jia X,Jiang SB

    更新日期:2010-11-01 00:00:00

  • The accuracy and reproducibility of a global method to correct for geometric image distortion in the x-ray imaging chain.

    abstract::A method to correct for geometric image distortion in the x-ray imaging chain, so-called dewarping, has been developed. A global two-dimensional polynomial model of which the degree is optimized is used. The performance of the method has been tested in a number of experiments using images of a plate with a 1 cm spaced...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598101

    authors: Gronenschild E

    更新日期:1997-12-01 00:00:00

  • Comparisons of treatment optimization directly incorporating systematic patient setup uncertainty with a margin-based approach.

    abstract:PURPOSE:To develop a probabilistic treatment planning (PTP) method which is robust to systematic patient setup errors and to compare PTP plans with plans generated using a planning target volume (PTV) margin optimized to give the same target coverage probability as the PTP plan. METHODS:Plans adhering to the RTOG-0126...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3679856

    authors: Moore JA,Gordon JJ,Anscher M,Silva J,Siebers JV

    更新日期:2012-02-01 00:00:00

  • A multimodality segmentation framework for automatic target delineation in head and neck radiotherapy.

    abstract:PURPOSE:To develop an automatic segmentation algorithm integrating imaging information from computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) to delineate target volume in head and neck cancer radiotherapy. METHODS:Eleven patients with unresectable disease at the tonsil...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4928485

    authors: Yang J,Beadle BM,Garden AS,Schwartz DL,Aristophanous M

    更新日期:2015-09-01 00:00:00