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Blood pressure percentiles in 22,051 German children and adolescents: The PEP Family Heart Study.

Abstract：

BACKGROUND:Strong associations between blood pressure (BP) and overweight raise the question whether overweight children (body mass index (BMI) ≥85th percentile) should be included in the normative database. METHODS:Using the LMS (Lamda-Mu-Sigma) method, we developed age-, gender-, and height-adjusted percentile curves for systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the 50th, 85th, 90th, 95th, and 97th percentiles in 22,051 German youths (18,917 normal-weight, 1,938 overweight, and 1,196 obese) aged 3-18 years from yearly cross-sectional surveys of the PEP Family Heart Study Nuremberg. RESULTS:Among children, we found no gender differences for BP and BMI. Male adolescents are taller and heavier. The mean prevalence of hypertension and obesity is 7.3% and 5.2% among children and 7.2% and 5.8% among adolescents, respectively. The prevalence of elevated BP increased substantially by weight groups achieving 24.4% in obese females and 21.9% in obese males with odds ratios of 5.9 (95% confidence interval (CI): 5.1-7.5) and 4.3 (95% CI: 3.5-5.2), respectively. The shapes of the 10 LMS-smoothed SBP and DBP percentile curves differ substantially between gender and weight group. The normal-weight percentiles are nearly identical with the overall growth charts, but separate percentiles for overweight and obese youths provide considerably higher values, such as 148/91 vs. 136/86 mm Hg for a 17-year-old male and 136/91 vs. 123/81 mm Hg for female, respectively, at the 90th percentile. CONCLUSIONS:Because of substantially higher BP percentiles, separate databases for overweight and obese children and adolescents are strongly recommended.

journal_name

Am J Hypertens

journal_title

American journal of hypertension

authors

Schwandt P,Scholze JE,Bertsch T,Liepold E,Haas GM

doi

10.1093/ajh/hpu208

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

672-9

issue

5

eissn

0895-7061

issn

1941-7225

pii

hpu208

journal_volume

28

pub_type

杂志文章,多中心研究

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