Abstract:
:The efficacy of recombinant interferon-alpha 2 in the treatment of advanced hairy cell leukaemia is investigated in 31 patients. Preliminary results show a complete and partial response rate of 69%. An optimal dose study utilizing maximal stimulation of an interferon-dependent pathway was carried out in 5 patients. The optimal dose of the order of 5 X 10(5) IU/day is effective and without side-effects. Interferon treatment did not enhance natural killer cell activity and therefore a direct mode of action upon tumour cells is proposed.
journal_name
Oncologyjournal_title
Oncologyauthors
Huber C,Flener R,Gastl Gdoi
10.1159/000226076subject
Has Abstractpub_date
1985-01-01 00:00:00pages
7-9eissn
0030-2414issn
1423-0232journal_volume
42 Suppl 1pub_type
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