Bigenotypic and biphenotypic appearance of immunoglobulin light chains in 1 of 3 non-Hodgkin's lymphoma xenografts.

abstract：:Twenty-two patients with metastatic breast carcinoma were treated with a combination of cisplatin (100 mg/m2 i.v. day 1) and etoposide (100 mg/m2 i.v. days 1-3). Eligible patients had measurable disease with normal organ functions, performance status < 3, age < 70 years and no previous chemotherapy for metastatic dise...

journal_title：Oncology

authors： Lluch A,Azagra P,Cervantes A,Muñoz M,Alberola V,Santabarbara P,García-Conde J

更新日期：1994-07-01 00:00:00

abstract：:Many of the previously proposed theories of carcinogenesis which relate the exposure level of a carcinogen to expected tumor response, are summarized and it is pointed out that these theories assume the existence of no threshold level. A modification of the one-hit carcinogenic model which would incorporate a threshol...

journal_title：Oncology

authors： Brown CC

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) has become prevalent in esophageal squamous cell carcinoma (ESCC), but its long-term prognostic advantages remain unclear. The latest prognostic outcomes in clinical Stage (cStage) II/III ESCC with NAC were herein elucidated. PATIENTS AND METHODS:NAC prior to curative treatmen...

journal_title：Oncology

authors： Yamashita K,Hosoda K,Moriya H,Katada C,Sugawara M,Mieno H,Komori S,Katada N,Watanabe M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Recent data suggest that capecitabine may have little efficacy in women with metastatic triple negative breast cancer (TNT). We have therefore retrospectively analysed capecitabine outcome in the TN subgroup of patients with locally advanced or metastatic breast cancer treated in our unit. PATIENTS AND METH...

journal_title：Oncology

authors： Kotsori AA,Dolly S,Sheri A,Parton M,Shaunak N,Ashley S,Walsh G,Johnston S,Smith IE

更新日期：2010-01-01 00:00:00

abstract：:A demonstration multiphasic cancer screening program was conducted in a rural village in Thailand under the coordination of Bangkok's National Cancer Institute. The village's physician, mayor, and other members of the community assumed a variety of volunteer roles in order to provide logistical support. In short, this...

journal_title：Oncology

authors： Lynch HT,Pitakspraiwan P,Sombooncharoen S,Phanthumchinda P,Vechmon U,Srivanwat G,Schutz RJ,Lynch JF

更新日期：1985-01-01 00:00:00

abstract：:The efficacy of recombinant interferon-alpha 2 in the treatment of advanced hairy cell leukaemia is investigated in 31 patients. Preliminary results show a complete and partial response rate of 69%. An optimal dose study utilizing maximal stimulation of an interferon-dependent pathway was carried out in 5 patients. Th...

journal_title：Oncology

authors： Huber C,Flener R,Gastl G

更新日期：1985-01-01 00:00:00

abstract：:Calcitriol (1,25-dihydroxycholecalciferol) has antiproliferative and/or proapoptotic effects on many cell types and the glucocorticoid dexamethasone enhances these effects. We have shown that calcitriol modulates several key signaling proteins involved in differentiation, proliferation and apoptosis in tumor-derived m...

journal_title：Oncology

authors： Flynn G,Chung I,Yu WD,Romano M,Modzelewski RA,Johnson CS,Trump DL

更新日期：2006-01-01 00:00:00

abstract：:This randomised, single-blind, parallel-group study was carried out in 48 French pneumology centres to compare the anti-emetic efficacy of ondansetron and an alizapride plus methylprednisolone (ALI/MPS) combination in patients receiving high-dose cisplatin. A total of 220 patients were recruited of whom 209 were evalu...

journal_title：Oncology

authors： Depierre A,Lebeau B,d'Allens H

更新日期：1992-01-01 00:00:00

abstract：:Malignant gastrointestinal neuroectodermal tumor (GNET) is an aggressive rare tumor, primarily occurring in young adults with frequent local-regional metastases and recurrence after local control. The tumor is characterized by the presence of EWSR1-ATF1 or EWSR1-CREB1 and immunohistochemical positivity for S-100 prote...

journal_title：Oncology

authors： Subbiah V,Holmes O,Gowen K,Spritz D,Amini B,Wang WL,Schrock AB,Meric-Bernstam F,Zinner R,Piha-Paul S,Zarzour M,Elvin JA,Erlich RL,Stockman DL,Vergilio JA,Suh JH,Stephens PJ,Miller V,Ross JS,Ali SM

更新日期：2016-01-01 00:00:00

abstract：:Thirteen samples of gastric tumors that had developed in the remnant stomach (remnant gastric cancer) were compared with 63 samples of primary gastric tumors located in the upper third of the stomach (primary gastric cancer) by both clinicopathologic and flow cytometric analysis. The depths of invasion of all these tu...

journal_title：Oncology

authors： Ikeguchi M,Kondou A,Oka A,Tsujitani S,Maeta M,Kaibara N

更新日期：1995-03-01 00:00:00

abstract：:Little is known about the expression and antioxidant function of manganese superoxide dismutase (Mn-SOD) in esophageal squamous cell carcinoma. To determine the significance of Mn-SOD in esophageal squamous cell carcinomas, Mn-SOD mRNA expression was examined in 45 esophageal squamous cell carcinomas and the correspon...

journal_title：Oncology

authors： Toh Y,Kuninaka S,Mori M,Oshiro T,Ikeda Y,Nakashima H,Baba H,Kohnoe S,Okamura T,Sugimachi K

更新日期：2000-09-01 00:00:00

abstract：:67Ga-subtraction scan was found to be useful and a promising new method for the pre-treatment evaluation of the patient with Hodgkin's disease or non-Hodgkin's lymphoma. The scan appeared to be most accurate in the neck, chest, and axillary regions. It appears to offer a means of increasing the accuracy of evaluating ...

journal_title：Oncology

authors： Krolikiewicz H,Maruyama Y,Deland FH,Beihn RM,Hafner T,Utley JF

更新日期：1977-01-01 00:00:00

abstract：:To assess the prognostic value of pretreatment serum neuron-specific enolase (NSE) in nonsmall cell lung cancer (NSCLC), levels were measured in 84 NSCLC patients, 40 healthy controls, and 20 patients with benign pulmonary diseases. NSE concentration was higher in NSCLC (11.7 +/- 10.8 ng/ml) (mean +/- SD; median = 9.7...

journal_title：Oncology

authors： Diez M,Torres A,Ortega L,Maestro M,Hernando F,Gomez A,Picardo A,Granell J,Balibrea JL

更新日期：1993-03-01 00:00:00

abstract：:In 35 children with acute lymphatic or undifferentiated leukemia, immunological properties of normal lymphocytes and lymphoblasts were investigated. In most cases the number of circulating normal lymphocytes with surface or B markers and delayed type hypersensitivity was depressed. On the other hand, the response to m...

journal_title：Oncology

authors： Winterleitner H,Rella W,Eibl M,Krepler P

更新日期：1978-01-01 00:00:00

abstract：:The aim of this study was to both develop and validate a nomogram based on the Ki-67 index to predict recurrence. We constructed a nomogram using the Cox proportional hazards model with 953 N0 and N1 postoperative hormone receptor (HR)-positive breast cancer patients and validated it in an external cohort of 895 patie...

journal_title：Oncology

authors： Park YH,Im SA,Cho EY,Ahn JH,Woo SY,Kim S,Keam B,Lee JE,Han W,Nam SJ,Park IA,Noh DY,Yang JH,Ahn JS,Im YH

更新日期：2014-01-01 00:00:00

abstract：:Canthaxanthin, a carotenoid with no vitamin A activity, was evaluated for its efficacy in the prevention of chemically induced mammary cancers. Canthaxanthin was administered in the diet at two dose levels (3,390 or 1,130 mg/kg diet). In the dimethylbenzanthracene-induced mammary cancer model, diet supplementation wit...

journal_title：Oncology

authors： Grubbs CJ,Eto I,Juliana MM,Whitaker LM

更新日期：1991-01-01 00:00:00

abstract：:Lymph node and distant metastasis were comparatively studied in 225 oral carcinomas, and factors predisposing toward metastasis were investigated using clinical and immunohistopathological approaches. Neither the sites of tumors nor T-stage was correlated with either type of metastasis. Tumor cell differentiation was ...

journal_title：Oncology

authors： Osaki T,Kimura T,Tatemoto Y,Yamamoto T,Yoneda K

更新日期：2000-02-01 00:00:00

abstract：:The registry of digestive cancer set up for the French department of Côte d'Or (455, 727) enables a morbidity study about esophageal cancer to be made among residents. The crude animal incidence rate was 16.7/100,000 for males and 1.2/100,000 for females. Corresponding age-standardized rates were 13.2 and 0.5. The sex...

journal_title：Oncology

authors： Faivre J,Milan C,Martin F,Michiels R,Cabanne F,Klepping C

更新日期：1981-01-01 00:00:00

abstract：:A transplantable transitional cell murine bladder tumor induced by N-[4-(5-nitro-2-furyl)-thiazolyl] formamide (FANFT) was characterized by tumor growth, survival time and response to chemotherapy drugs, cis-dichloro-trans-dihydroxy-bis-iso-propylamine platinum IV (CHIP), cis- diaminedichloro platinum II (DDP), cyclop...

journal_title：Oncology

authors： Murphy GP,Pontes JE,Williams PD

更新日期：1984-01-01 00:00:00

abstract：:Cancer causation in humans is at least a three-dimensional problem too often viewed from only two dimensions, especially as far as the two-dimensional results (dose versus response) of cancer induction tests in animals are viewed. The expression of a cancer represents a critical convergence of additional factors in th...

journal_title：Oncology

authors： Kolbye AC Jr

更新日期：1976-01-01 00:00:00

abstract：:Gastrointestinal stem cells have the capacity for long-term self-replication and the ability to give rise to all other epithelial cell lineages. These properties make them essential since they maintain tissue homeostasis by regulating cell turnover depending on the current demand. However, they are also important play...

journal_title：Oncology

authors： Schier S,Wright NA

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES AND METHODS:The association oxaliplatin (OXA)-5-fluorouracil/folinic acid (FUFA) is currently a standard first-line treatment for advanced colorectal cancer. The main objective of this experimental study was to examine the cytotoxic effects resulting from the addition of ionizing radiation (Rgamma) to the co...

journal_title：Oncology

authors： Magné N,Fischel JL,Formento P,Etienne MC,Dubreuil A,Marcié S,Lagrange JL,Milano G

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for differentiating benign from malignant lesions, evaluating tumor stage, monitoring the response to therapy and detecting tumor recurrence in a variety of malignancies. Nevertheless, its use in patients with hepatocellular carcinoma (H...

journal_title：Oncology

authors： Yoon KT,Kim JK,Kim DY,Ahn SH,Lee JD,Yun M,Rha SY,Chon CY,Han KH

更新日期：2007-01-01 00:00:00

abstract：:CA 19-9 and tissue polypeptide antigen (TPA) were determined in the sera of 28 control subjects, 29 patients with pancreatic cancer, 26 with chronic pancreatitis and 62 with benign and malignant extra pancreatic diseases in order to compare their usefulness in diagnosing pancreatic cancer, to verify whether the combin...

journal_title：Oncology

authors： Basso D,Fabris C,Del Favero G,Panucci A,Plebani M,Angonese C,Leandro G,Dodi G,Burlina A,Naccarato R

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:It is well recognized that distinguishing benign from malignant papillary lesions of the breast may pose challenging diagnostic problems. To prospectively evaluate the potential role of mammography, ultrasound and image-guided core biopsy in the diagnosis of papillary lesions of the breast. METHODS:1,442 wo...

journal_title：Oncology

authors： Puglisi F,Zuiani C,Bazzocchi M,Valent F,Aprile G,Pertoldi B,Minisini AM,Cedolini C,Londero V,Piga A,Di Loreto C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The prognosis of patients with locally advanced squamous cell carcinoma (SCC) of the tongue is poor. Postoperative chemoradiotherapy (CRT) improves locoregional control and survival in high-risk patients. We investigated the prognostic factors for clinical T4a tongue SCC, and elucidated whether postoperative ...

journal_title：Oncology

authors： Yokota T,Iida Y,Ogawa H,Kamijo T,Onozawa Y,Todaka A,Hamauchi S,Onoe T,Nakagawa M,Yurikusa T,Tanuma A,Yamashita A,Nishimura T,Yasui H,Onitsuka T

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Transcatheter arterial chemoembolization (TACE) is a standard therapy used in the treatment of intermediate hepatocellular carcinoma (HCC). Recently, balloon-occluded TACE (B-TACE) has been developed. PURPOSE:This study aimed to clarify the effects of B-TACE in patients with HCC, with a focus on which drug ...

journal_title：Oncology

authors： Shirono T,Iwamoto H,Niizeki T,Shimose S,Nakano M,Satani M,Okamura S,Noda Y,Kamachi N,Kuromatsu R,Sakai M,Nomiyama M,Kuwano T,Tanaka M,Koga H,Torimura T

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. METHODS:From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A pa...

journal_title：Oncology

authors： Stathopoulos GP,Batziou C,Trafalis D,Koutantos J,Batzios S,Stathopoulos J,Legakis J,Armakolas A

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies in China and, due to the limited efficacy of currently available therapies, is responsible for a large number of deaths. IFN-alpha therapy has shown promise in the treatment of various forms of human cancer and is considered in the trea...

journal_title：Oncology

authors： Wu WZ,Sun HC,Gao YQ,Li Y,Wang L,Zhou K,Liu KD,Iliakis G,Tang ZY

更新日期：2004-01-01 00:00:00

abstract：:To determine the relationship between neoplastic transformation and increased genetic instability, spontaneous and induced mutation rates were compared in a nontumorigenic, immortalized human bronchial epithelial cell line (NL20) and a tumorigenic cell line (NL20T) spontaneously derived from the NL20 line. Using the h...

journal_title：Oncology

authors： Wittenkeller JL,Storer B,Bittner G,Schiller JH

更新日期：1997-07-01 00:00:00