Impairment of host cell ribonucleic acid polymerase II after infection with frog virus 3.

abstract：:The diverse sequences of viral populations within individual hosts are the starting material for selection and subsequent evolution of RNA viruses such as foot-and-mouth disease virus (FMDV). Using next-generation sequencing (NGS) performed on a Genome Analyzer platform (Illumina), this study compared the viral popula...

journal_title：Journal of virology

authors： Wright CF,Morelli MJ,Thébaud G,Knowles NJ,Herzyk P,Paton DJ,Haydon DT,King DP

更新日期：2011-03-01 00:00:00

abstract：:Tryptic peptide maps were prepared for four purified structural proteins derived from several murine leukemia viruses (MuLV's). Analyses of these peptide maps reveal that the p30 proteins of Rauscher, Moloney, and Gross MuLV's are very similar to each other, as are the p10's obtained from these three viruses. In contr...

journal_title：Journal of virology

authors： Buchhagen DL,Stutman O,Fleissner E

更新日期：1975-05-01 00:00:00

abstract：:Cellular inhibitor of apoptosis protein 2 (cIAP2) is a potent suppressor of apoptotic cell death. We have shown previously that cIAP2 is involved in the tumor necrosis factor alpha (TNF-α)-induced anti-hepatitis B virus (HBV) response; however, the mechanism for this antiviral effect remains unclear. In the present st...

journal_title：Journal of virology

authors： Wang Z,Ni J,Li J,Shi B,Xu Y,Yuan Z

更新日期：2011-11-01 00:00:00

abstract：:The ATP-dependent DNase activity of Escherichia coli disappeared or was markedly reduced after infection with double-stranded DNA phages, T2, T3, T4, T5, T6, T7, lambda, phi80, and P1, but not with the single-stranded DNA phage f1, or the RNA phage Qbeta. This DNase activity was not reduced when chloramphenicol was ad...

journal_title：Journal of virology

authors： Sakaki Y

更新日期：1974-12-01 00:00:00

abstract：:Muscle is an attractive target for gene delivery because of its mass and because vectors can be delivered in a noninvasive fashion. Adeno-associated virus (AAV) has been shown to be effective for muscle-targeted gene transfer. Recent progress in characterization of AAV serotype 1 (AAV1) and AAV6 demonstrated that thes...

journal_title：Journal of virology

authors： Hauck B,Xiao W

更新日期：2003-02-01 00:00:00

abstract：UNLABELLED:Semen enhances HIV infection in vitro, but how long it retains this activity has not been carefully examined. Immediately postejaculation, semen exists as a semisolid coagulum, which then converts to a more liquid form in a process termed liquefaction. We demonstrate that early during liquefaction, semen exh...

journal_title：Journal of virology

authors： Roan NR,Liu H,Usmani SM,Neidleman J,Müller JA,Avila-Herrera A,Gawanbacht A,Zirafi O,Chu S,Dong M,Kumar ST,Smith JF,Pollard KS,Fändrich M,Kirchhoff F,Münch J,Witkowska HE,Greene WC

更新日期：2014-07-01 00:00:00

abstract：:Dactylosporangiophage A1 has a polygonal head (75 nm) with spherical capsomeres (3 nm) and a noncontractile tail (200 by 10 nm) with cross-striations which is terminated with at least three prongs which are used for attachment. It contains double-stranded deoxyribonucleic acid and produces very little lysis. Intracell...

journal_title：Journal of virology

authors： Higgins ML,Lechevalier MP

更新日期：1969-02-01 00:00:00

abstract：:Mutant recombinant respiratory syncytial viruses (RSV) which cannot express the NS1 and M2-2 proteins, designated rA2DeltaNS1 and rA2DeltaM2-2, respectively, were evaluated as live-attenuated RSV vaccines. The rA2DeltaNS1 virus contains a large deletion that should have the advantageous property of genetic stability d...

journal_title：Journal of virology

authors： Teng MN,Whitehead SS,Bermingham A,St Claire M,Elkins WR,Murphy BR,Collins PL

更新日期：2000-10-01 00:00:00

abstract：:Human herpesvirus 8 (HHV-8) is likely to be involved in the pathogenesis of Kaposi's sarcoma (KS) and body cavity-based lymphomas (BCBLs). The HHV-8 genome is primarily in a latent state in BCBL-derived cell lines like BCBL-1, but lytic replication can be induced by phorbol esters (R. Renne, W. Zhang, B. Herndier, M. ...

journal_title：Journal of virology

authors： Raab MS,Albrecht JC,Birkmann A,Yağuboğlu S,Lang D,Fleckenstein B,Neipel F

更新日期：1998-08-01 00:00:00

abstract：:Hepatitis delta antigen (HDAg) is the only known protein of hepatitis delta virus and was previously shown to localize in the nucleoplasm of infected liver cells. In this study, nuclear localization signals of HDAg were defined by expressing various domains of the antigen in both hepatic and nonhepatic cells as beta-g...

journal_title：Journal of virology

authors： Chang MF,Chang SC,Chang CI,Wu K,Kang HY

更新日期：1992-10-01 00:00:00

abstract：:The complete genome sequences of the human coronavirus OC43 (HCoV-OC43) laboratory strain from the American Type Culture Collection (ATCC), and a HCoV-OC43 clinical isolate, designated Paris, were obtained. Both genomes are 30,713 nucleotides long, excluding the poly(A) tail, and only differ by 6 nucleotides. These si...

journal_title：Journal of virology

authors： St-Jean JR,Jacomy H,Desforges M,Vabret A,Freymuth F,Talbot PJ

更新日期：2004-08-01 00:00:00

abstract：:Five human recombinant Fab fragments (Fabs) specific for measles virus (MV) proteins were isolated from three antibody phage display libraries generated from RNAs derived from bone marrow or splenic lymphocytes from three MV-immune individuals. All Fabs reacted in an enzyme-linked immunosorbent assay with MV antigens....

journal_title：Journal of virology

authors： de Carvalho Nicacio C,Williamson RA,Parren PW,Lundkvist A,Burton DR,Björling E

更新日期：2002-01-01 00:00:00

abstract：:Murine cytomegalovirus (MCMV) proteins m142 and m143 are essential for viral replication. They bind double-stranded RNA and prevent protein kinase R-induced protein synthesis shutoff. Whether the two viral proteins have additional functions such as their homologs in human cytomegalovirus do remained unknown. We show t...

journal_title：Journal of virology

authors： Ostermann E,Warnecke G,Waibler Z,Brune W

更新日期：2015-10-28 00:00:00

abstract：:At mucosal sites, papillomavirus genomes can persist in the epithelial basal layer following immune-mediated regression. Subsequent T-cell depletion stimulates a 3- to 5-log increase in the viral copy number, to levels associated with productive infection. Reappearance of microlesions was rare within the short time fr...

journal_title：Journal of virology

authors： Maglennon GA,McIntosh PB,Doorbar J

更新日期：2014-01-01 00:00:00

abstract：:The human cytidine deaminase Apobec3F (h-A3F), a protein related to the previously recognized antiviral factor Apobec3G (h-A3G), has antiviral activity against human immunodeficiency virus type 1 (HIV-1) that is suppressed by the viral protein Vif. The mechanism of HIV-1 Vif-mediated suppression of h-A3F is not fully ...

journal_title：Journal of virology

authors： Liu B,Sarkis PT,Luo K,Yu Y,Yu XF

更新日期：2005-08-01 00:00:00

abstract：:Latent membrane protein 2A (LMP2A) is one of only two viral proteins expressed during latent Epstein-Barr virus (EBV) infections in human peripheral B cells. LMP2A blocks B-cell receptor (BCR) signal transduction in vitro by modulation of the Syk and Lyn protein tyrosine kinases. Five genetically unique LMP2A transgen...

journal_title：Journal of virology

authors： Caldwell RG,Brown RC,Longnecker R

更新日期：2000-02-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) major immediate-early protein IE1 is an abundant 72-kDa nuclear phosphoprotein that is thought to play an important role in efficient triggering of the lytic cycle, especially at low multiplicity of infection. The best-known properties of IE1 at present are its transient targeting to punct...

journal_title：Journal of virology

authors： Xu Y,Ahn JH,Cheng M,apRhys CM,Chiou CJ,Zong J,Matunis MJ,Hayward GS

更新日期：2001-11-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS, which has important impacts on the pig industry. PRRSV infection results in disruption of the swine leukocyte antigen class I (SLA-I) antigen presentation pathway. In this study, highly pathogenic PRRSV (HP-PRRSV) infection inh...

journal_title：Journal of virology

authors： Qi P,Liu K,Wei J,Li Y,Li B,Shao D,Wu Z,Shi Y,Tong G,Qiu Y,Ma Z

更新日期：2017-02-14 00:00:00

abstract：:Swainsonine, an inhibitor of glycoprotein processing, inhibits the formation of the normal oligosaccharide chain of the G protein of vesicular stomatitis virus. Thus, when vesicular stomatitis virus was grown in baby hamster kidney cells in the presence of swainsonine (15 to 500 ng/ml) and labeled with [2-(3)H]mannose...

journal_title：Journal of virology

authors： Kang MS,Elbein AD

更新日期：1983-04-01 00:00:00

abstract：:The replication of vaccinia virus is thought to take place exclusively in the cytoplasm of host cells. However, using DNA-DNA hybridization techniques, it can be shown that a significant fraction of the synthesis of vaccinia DNA takes place in the nucleus as well as the cytoplasm. The (3H) thymiding pulse-labeled vacc...

journal_title：Journal of virology

authors： LaColla P,Weissbach A

更新日期：1975-02-01 00:00:00

abstract：:Coronavirus envelope (E) proteins are small (approximately 75- to 110-amino-acid) membrane proteins that have a short hydrophilic amino terminus, a relatively long hydrophobic membrane domain, and a long hydrophilic carboxy-terminal domain. The protein is a minor virion structural component that plays an important, no...

journal_title：Journal of virology

authors： Ye Y,Hogue BG

更新日期：2007-04-01 00:00:00

abstract：:Nine virulent bacteriophages of the anaerobe Corynebacterium (Propionibacterium) acnes, the P-a series, are DNA phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. They have isometric heads (420 by 460 nm), and are placed in Bradley's group B-1. There is permanent plaque suppression a...

journal_title：Journal of virology

authors： Zierdt CH

更新日期：1974-11-01 00:00:00

abstract：:Influenza A viruses (IAVs) are viral pathogens that cause epidemics and occasional pandemics of significant mortality. The generation of efficacious vaccines and antiviral drugs remains a challenge due to the rapid appearance of new influenza virus types and antigenic variants. Consequently, novel strategies for the p...

journal_title：Journal of virology

authors： Jiang M,Österlund P,Westenius V,Guo D,Poranen MM,Bamford DH,Julkunen I

更新日期：2019-02-05 00:00:00

abstract：:Members of the Paramyxovirinae subfamily rely on the concerted action of two envelope glycoprotein complexes, attachment protein H and the fusion (F) protein oligomer, to achieve membrane fusion for viral entry. Despite advances in X-ray information, the organization of the physiological attachment (H) oligomer in fun...

journal_title：Journal of virology

authors： Brindley MA,Plemper RK

更新日期：2010-12-01 00:00:00

abstract：:We have presented a new approach to studying bacteriophage T4 head maturation. Using a modified M-band technique, we have shown that progeny deoxyribonucleic acid (DNA) was synthesized on the host cell membrane throughout infection. This DNA was released from the membrane later in infection as the result of formation ...

journal_title：Journal of virology

authors： Siegel PJ,Schaechter M

更新日期：1973-03-01 00:00:00

abstract：:Recently, we showed that the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) VP80 protein is essential for the formation of both virion types, budded virus (BV) and occlusion-derived virus (ODV). Deletion of the vp80 gene did not affect assembly of nucleocapsids. However, these nucleocapsids were not ...

journal_title：Journal of virology

authors： Marek M,Merten OW,Galibert L,Vlak JM,van Oers MM

更新日期：2011-06-01 00:00:00

abstract：:Infectious leukemia virus production by two chronically infected NIH/MOL lines was strongly inhibited by interferon treatment of the cells. The corresponding degree of inhibition in JLSV-11 cells was much lower. Multiplication of encephalomyocarditis virus in all three cell lines was barely affected by interferon trea...

journal_title：Journal of virology

authors： Sen GC,Herz RE

更新日期：1983-03-01 00:00:00

abstract：:A recombinant adenovirus was constructed by inserting the human immunodeficiency virus type 1 (HIV-1) envelope gene downstream from the early region 3 (E3) promoter of adenovirus type 5 (Ad5), replacing the coding sequences of E3. The recombinant virus replicated as efficiently as the parent virus in all cell lines te...

journal_title：Journal of virology

authors： Dewar RL,Natarajan V,Vasudevachari MB,Salzman NP

更新日期：1989-01-01 00:00:00

abstract：:The genome of the defective interfering (DI) mouse hepatitis virus DI-a carries a large open reading frame (ORF) consisting of ORF1a, ORF1b, and nucleocapsid sequences. To test whether this fusion ORF is important for DI virus replication, we constructed derivatives of the DI-a genome in which the reading frame was tr...

journal_title：Journal of virology

authors： de Groot RJ,van der Most RG,Spaan WJ

更新日期：1992-10-01 00:00:00

abstract：:The ability of viruses to control and/or evade the host antiviral response is critical to the establishment of a productive infection. We have previously shown that West Nile virus NY (WNV-NY) delays activation of interferon regulatory factor 3 (IRF-3), a transcription factor critical to the initiation of the antivira...

journal_title：Journal of virology

authors： Fredericksen BL,Gale M Jr

更新日期：2006-03-01 00:00:00