Deoxyribonucleic acid synthesis in bacteriophage SPO1-infected Bacillus subtilis. I. Bacteriophage deoxyribonucleic acid synthesis and fate of host deoxyribonucleic acid in normal and polymerase-deficient strains.

abstract：:Mouse-hamster somatic cell hybrids were used to show that the recombinant mink cell focus-forming murine leukemia viruses and their ecotropic virus progenitors require different mouse chromosomes for replication. Mouse chromosome 1 was shown to carry the genetic information necessary for the replication of six differe...

journal_title：Journal of virology

authors： Kozak CA

更新日期：1983-10-01 00:00:00

abstract：:Treatment of Friend erythroleukemia cells (FLC) with gamma interferon (IFN-gamma) in the presence of anti-IFN-beta antibodies reduces the effectiveness of the antiviral state and the induction of 2'-5'-oligoadenylate synthetase activity, indicating that the antiviral activity of IFN-gamma in FLC is in part mediated by...

journal_title：Journal of virology

authors： Marziali G,Fiorucci G,Coccia EM,Percario Z,Raber J,Battistini A,Rossi GB,Affabris E,Romeo G

更新日期：1991-08-01 00:00:00

abstract：:The initiation of human immunodeficiency virus type 1 (HIV-1) reverse transcription occurs at a site in the viral RNA genome which is designated the primer-binding site (PBS). The HIV-1 PBS is an 18-nucleotide sequence that is complementary to the 3'-terminal 18 nucleotides of tRNA(3Lys), which is used as the primer f...

journal_title：Journal of virology

authors： Wakefield JK,Wolf AG,Morrow CD

更新日期：1995-10-01 00:00:00

abstract：:A molecular clone of mouse-neuroadapted yellow fever 17D virus (SPYF-MN) was used to identify critical determinants of viral neuroinvasiveness in a SCID mouse model. Virus derived from this clone differs from nonneuroinvasive YF5.2iv virus at 29 nucleotide positions, encoding 13 predicted amino acid substitutions and ...

journal_title：Journal of virology

authors： Nickells M,Chambers TJ

更新日期：2003-11-01 00:00:00

abstract：:The folded genome of Escherichia coli is converted to a slower-sedimenting form within 5 min after infection with bacteriophage T4 or T4nd28(den A)-amN82(44). Chloramphenicol sensitivity and response to UV-irradiation of the phage suggest participation of viral-induced functions. ...

journal_title：Journal of virology

authors： Tutas DJ,Wehner JM,Koerner JF

更新日期：1974-02-01 00:00:00

abstract：:The entry of animal viruses into cells is associated with permeabilization of the infected cells to protein toxins such as alpha-sarcin (C. Fernández-Puentes and L. Carrasco, Cell 20:769-775, 1980). This phenomenon has been referred to as "the early permeabilization by animal viruses" (L. Carrasco, Virology 113:623-62...

journal_title：Journal of virology

authors： Almela MJ,González ME,Carrasco L

更新日期：1991-05-01 00:00:00

abstract：:We have generated hexon-modified adenovirus serotype 5 (Ad5) vectors that are not neutralized by Ad5-specific neutralizing antibodies in mice. These vectors are attractive for the advancement of vaccine products because of their potential for inducing robust antigen-specific immune responses in people with prior expos...

journal_title：Journal of virology

authors： Bruder JT,Chen P,Semenova E,Thomas CA,Konovalova S,Ekberg G,Ettyreddy D,McVey D,Gall JG,King CR,Brough DE

更新日期：2013-09-01 00:00:00

abstract：:Brome mosaic virus (BMV) RNA replication is directed by two virus-encoded proteins, 1a and 2a. The amino-terminal half of 1a is a distant homolog of alphavirus nonstructural protein nsP1, which has been implicated in capping viral RNAs. In this study, we examined the enzymatic activities of BMV 1a expressed in yeast, ...

journal_title：Journal of virology

authors： Ahola T,Ahlquist P

更新日期：1999-12-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) readily infects both humans and chimpanzees, but the pathologic outcomes of infection in these two species differ greatly. In attempts to identify virus-cell interactions that might account for this differential pathogenicity, chimpanzee peripheral blood lymphocytes and ...

journal_title：Journal of virology

authors： Watanabe M,Ringler DJ,Fultz PN,MacKey JJ,Boyson JE,Levine CG,Letvin NL

更新日期：1991-06-01 00:00:00

abstract：:Phenol-extracted, infectious deoxyribonucleic acid (DNA) species from phi105 phage particles, from phi105 lysogenic bacteria, and from induced phi105 lysogenic bacteria were sedimented in sucrose gradients. Infectious DNA from phi105 particles sedimented like the bulk of mature phage DNA in neutral sucrose. Infectivit...

journal_title：Journal of virology

authors： Rutberg L,Rutberg B

更新日期：1970-05-01 00:00:00

abstract：:The human foamy virus (HFV) contains within the U3 region of its long terminal repeat (LTR) three perfect consensus sequences for the binding of the inducible transcription factor AP-1. Results of DNase I footprint protection and gel retardation assays demonstrated that proteins in extracts of HeLa and BHK-21 cells as...

journal_title：Journal of virology

authors： Maurer B,Serfling E,ter Meulen V,Rethwilm A

更新日期：1991-11-01 00:00:00

abstract：:Typical herpes simplex virus (HSV) capsids contain seven proteins that form a T=16 icosahedron of 1,250-A diameter. Infection of cells with recombinant baculoviruses expressing two of these proteins, VP5 (which forms the pentons and hexons in typical HSV capsids) and VP19C (a component of the triplexes that connect ad...

journal_title：Journal of virology

authors： Saad A,Zhou ZH,Jakana J,Chiu W,Rixon FJ

更新日期：1999-08-01 00:00:00

abstract：:Vaccination is the most effective way to prevent influenza virus infections. However, the diversity of antigenically distinct isolates is a challenge for vaccine development. In order to overcome the antigenic variability and improve the protective efficacy of influenza vaccines, our research group has pioneered the d...

journal_title：Journal of virology

authors： Huang Y,Owino SO,Crevar CJ,Carter DM,Ross TM

更新日期：2020-02-28 00:00:00

abstract：:Numerous RNA viruses generate subgenomic mRNAs (sgRNAs) for expression of their 3'-proximal genes. A major step in control of viral gene expression is the regulation of sgRNA synthesis by specific promoter elements. We used barley yellow dwarf virus (BYDV) as a model system to study transcriptional control in a virus ...

journal_title：Journal of virology

authors： Koev G,Miller WA

更新日期：2000-07-01 00:00:00

abstract：:Monoclonal antibodies (MAbs) against the rubella virion were used to locate epitopes involved in hemagglutination and neutralization. The MAbs exhibiting high-level hemagglutination-inhibiting activity were shown by Western blot analysis to be specific for the E1 polypeptide; this is consistent with the presence of th...

journal_title：Journal of virology

authors： Green KY,Dorsett PH

更新日期：1986-03-01 00:00:00

abstract：:As a subunit of both the P-L polymerase complex and the P-N assembly complex, the vesicular stomatitis virus (VSV) P protein plays a pivotal role in transcription and replication of the viral genome. Constitutive phosphorylation of this protein is currently thought to be essential for formation of the P-L complex. We ...

journal_title：Journal of virology

authors： Spadafora D,Canter DM,Jackson RL,Perrault J

更新日期：1996-07-01 00:00:00

abstract：:Mycophenolic acid (MPA), an inhibitor of IMP dehydrogenase, inhibits reovirus replication and viral RNA and protein production. In mouse L929 cells, antiviral effects were greatest at 30 microg of MPA/ml. At this dosage, MPA inhibited replication of reovirus strain T3D more than 1,000-fold and inhibited replication of...

journal_title：Journal of virology

authors： Hermann LL,Coombs KM

更新日期：2004-06-01 00:00:00

abstract：:Research in the last 2 decades has demonstrated that a specific organelle of the cell nucleus, termed PML nuclear body (PML-NB) or nuclear domain 10 (ND10), is frequently modified during viral infection. This correlates with antagonization of a direct repressive function of individual PML-NB components, such as the PM...

journal_title：Journal of virology

authors： Scherer M,Stamminger T

更新日期：2016-06-10 00:00:00

abstract：:A putative transcription factor, C/EBP, isolated from rat liver nuclei, has been shown to bind to at least two different sequence motifs: the CCAAT promoter domain and a core sequence [GTGG(T/A)(T/A)(T/A)G] common to many viral enhancers, including simian virus 40 and human hepatitis B virus. It has been proposed that...

journal_title：Journal of virology

authors： Pei DQ,Shih CH

更新日期：1990-04-01 00:00:00

abstract：:The Roseobacter clade has been recognized as one of the abundant bacterial lineages in marine environments, which makes the characterization of bacteriophages infecting members of the clade important. Here we report the complete genome sequence of bacteriophage P12053L, which infects Celeribacter sp. strain IMCC12053,...

journal_title：Journal of virology

authors： Kang I,Jang H,Oh HM,Cho JC

更新日期：2012-08-01 00:00:00

abstract：UNLABELLED:Due to a scarcity of immunocompetent animal models for viral hepatitis, little is known about the early innate immune responses in the liver. In various hepatotoxic models, both pro- and anti-inflammatory activities of recruited monocytes have been described. In this study, we compared the effect of liver in...

journal_title：Journal of virology

authors： Movita D,van de Garde MD,Biesta P,Kreefft K,Haagmans B,Zuniga E,Herschke F,De Jonghe S,Janssen HL,Gama L,Boonstra A,Vanwolleghem T

更新日期：2015-05-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) mutants with codon insertions and deletions in IE-0, the gene encoding ICP0, were constructed. The HSV-1 deletion mutant dl1403 (N. D. Stow and E. C. Stow, J. Gen. Virol. 67:2571-2585, 1986) and an IE-0:lacZ transplacement vector isolated in this study were used to facilitate the co...

journal_title：Journal of virology

authors： Chen J,Silverstein S

更新日期：1992-05-01 00:00:00

abstract：:The cellular protein bone marrow stromal antigen-2 (BST-2)/tetherin acts against a variety of enveloped viruses by restricting their release from the plasma membrane. The HIV-1 accessory protein Vpu counteracts BST-2 by downregulating it from the cell surface and displacing it from virion assembly sites. Previous comp...

journal_title：Journal of virology

authors： Sharma S,Jafari M,Bangar A,William K,Guatelli J,Lewinski MK

更新日期：2019-05-15 00:00:00

abstract：:Of the numerous endogenous retroviral elements that are present in the human genome, the abundant HERV-K family is distinct because several members are transcriptionally active and coding for biologically active proteins. A detailed phylogeny of the HERV-K family based on the partial sequence of the reverse transcript...

journal_title：Journal of virology

authors： Berkhout B,Jebbink M,Zsíros J

更新日期：1999-03-01 00:00:00

abstract：:In July 1991, an influenza A virus, designated A/Maryland/12/91 (A/MD), was isolated from the bronchial secretions of a 27-year-old animal caretaker. He had been admitted to the hospital with bilateral pneumonia and died of acute respiratory distress syndrome 13 days later. Antigenic analyses with postinfection ferret...

journal_title：Journal of virology

authors： Wentworth DE,Thompson BL,Xu X,Regnery HL,Cooley AJ,McGregor MW,Cox NJ,Hinshaw VS

更新日期：1994-04-01 00:00:00

abstract：:The Hsp70 chaperone plays a central role in multiple processes within cells, including protein translation, folding, intracellular trafficking, and degradation. This protein is implicated in the replication of numerous viruses. We have shown that rabies virus infection induced the cellular expression of Hsp70, which a...

journal_title：Journal of virology

authors： Lahaye X,Vidy A,Fouquet B,Blondel D

更新日期：2012-05-01 00:00:00

abstract：UNLABELLED:Like most positive-strand RNA viruses, infection by plant tombusviruses results in extensive rearrangement of specific host cell organelle membranes that serve as the sites of viral replication. The tombusvirus Tomato bushy stunt virus (TBSV) replicates within spherules derived from the peroxisomal boundary ...

journal_title：Journal of virology

authors： Richardson LG,Clendening EA,Sheen H,Gidda SK,White KA,Mullen RT

更新日期：2014-06-01 00:00:00

abstract：:The replication of positive-strand RNA viral genomes involves various cis-acting RNA sequences. Generally, regulatory RNA sequences are present at or near genomic termini; however, internal replication elements (IREs) also exist. Here we report the structural and functional characterization of an IRE present in the re...

journal_title：Journal of virology

authors： Monkewich S,Lin HX,Fabian MR,Xu W,Na H,Ray D,Chernysheva OA,Nagy PD,White KA

更新日期：2005-04-01 00:00:00

abstract：:Protein synthesis in adenovirus-infected cells is regulated during the late phase of infection. The rate of initiation is maintained by a small viral RNA, virus-associated (VA) RNAI, which prevents the phosphorylation of eukaryotic initiation factor eIF-2 by a double-stranded RNA-activated protein kinase, DAI. On the ...

journal_title：Journal of virology

authors： Pe'ery T,Mellits KH,Mathews MB

更新日期：1993-06-01 00:00:00

abstract：:Parvovirus capsids are assembled from multiple forms of a single protein and are quite stable structurally. However, in order to infect cells, conformational plasticity of the capsid is required and this likely involves the exposure of structures that are buried within the structural models. The presence of functional...

journal_title：Journal of virology

authors： Nelson CD,Minkkinen E,Bergkvist M,Hoelzer K,Fisher M,Bothner B,Parrish CR

更新日期：2008-11-01 00:00:00