Base composition and hybridization studies of the three double-stranded RNA segments of bacteriophage phi 6.

Abstract:

:The three double-stranded ribonucleic acid (dsRNA) segments of the bacteriophage phi6 were isolated and shown to have similar melting temperatures and base compositions. RNA:RNA hybridization experiments with the isolated segments eliminate the possibility that the two smaller dsRNA segments arise from a cleavage of the large dsRNA segment. The two smaller RNA segments reanneal rapidly even at low temperatures; in contrast, the large dsRNA reannealed only at higher temperatures. Evidence is also presented which suggests that the dsRNAs may contain a short single-stranded RNA tail.

journal_name

J Virol

journal_title

Journal of virology

authors

Van Etten JL,Vidaver AK,Koski RK,Burnett JP

doi

10.1128/JVI.13.6.1254-1262.1974

subject

Has Abstract

pub_date

1974-06-01 00:00:00

pages

1254-62

issue

6

eissn

0022-538X

issn

1098-5514

journal_volume

13

pub_type

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