Abstract:
:Within this review article we describe recent developments in asymmetric catalysis with peptides. Numerous peptides have been established in the past two decades that catalyze a wide variety of transformations with high stereoselectivities and yields, as well as broad substrate scope. We highlight here catalytically active peptides, which have addressed challenges that had thus far remained elusive in asymmetric catalysis: enantioselective synthesis of atropoisomers and quaternary stereogenic centers, regioselective transformations of polyfunctional substrates, chemoselective transformations, catalysis in-flow and reactions in aqueous environments.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Lewandowski B,Wennemers Hdoi
10.1016/j.cbpa.2014.09.011subject
Has Abstractpub_date
2014-10-01 00:00:00pages
40-6eissn
1367-5931issn
1879-0402pii
S1367-5931(14)00123-9journal_volume
22pub_type
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