Abstract:
:Biosensors use biological elements to detect or quantify an analyte of interest. In bioprocessing, biosensors are employed to monitor key metabolites. There are two main types: fully biological systems or biological recognition coupled with physical/chemical detection. New developments in chemical biosensors include multiplexed detection using microfluidics. Synthetic biology can be used to engineer new biological biosensors with improved characteristics. Although there have been few biosensors developed for bioprocessing thus far, emerging trends can be applied in the future. A range of new platform technologies will enable rapid engineering of new biosensors based on transcriptional activation, riboswitches, and Förster Resonance Energy Transfer. However, translation to industry remains a challenge and more research into the robustness biosensors at scale is needed.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Dekker L,Polizzi KMdoi
10.1016/j.cbpa.2017.05.014subject
Has Abstractpub_date
2017-10-01 00:00:00pages
31-36eissn
1367-5931issn
1879-0402pii
S1367-5931(17)30073-Xjournal_volume
40pub_type
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