Abstract:
:With a view to developing a schedule for the ambulatory treatment of Schistosoma haematobium infection with sodium antimony dimercaptosuccinate (TWSb), a trial was conducted in Tanzania of the comparative effectiveness of daily and weekly injections of TWSb in schoolchildren. In-patients received five daily injections of 6 mg/kg, and out-patients the same total amount in five weekly injections.It was found that the two schedules were equally effective, and that, while the cure rate varied inversely with the intensity of infection as assessed by egg output, the reduction in egg output of groups of patients was reasonably constant regardless of the initial egg load.The author suggests that in the evaluation of drugs for schistosomal infection regard should be had to the intensity of infection and that the percentage reduction in egg output should be investigated as an additional index of therapeutic effectiveness.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Jordan Psubject
Has Abstractpub_date
1965-01-01 00:00:00pages
553-6issue
4eissn
0042-9686issn
1564-0604journal_volume
33pub_type
杂志文章abstract::Indirect immunofluorescence (IF) was used to localize stage-specific antigen(s) on the surface of the sporozoite membrane. The authors examined the feasibility of using an IF assay to determine whether an antisporozoite response is developed by individuals living in endemic areas. The specificity and sensitivity of th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Separation and concentration of parasitized erythrocytes from infected blood was achieved by centrifugation of a sample placed in a layer on top of a cushion of a Ficoll solution with a critical density. Pure suspensions of parasitized erythrocytes were obtained from Plasmodium berghei infected rodent blood, whereas r...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:INTRODUCTION:In 1996 we conducted a cross-sectional survey to study the epidemiology of smoking among Kuwaiti adults. METHODS:The 4000 participants were selected using a three-stage stratified cluster sampling design. Altogether 3859 participants (1798 males, 2061 females) returned a completed self-administered questi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::DDE and the o,p' and p,p' isomers of DDT were assayed in 94 human biopsy fat samples from hospitals in Delhi by gas chromatography. DDT was present in all except 2 samples at concentrations from 0.17 to 176.5 mg per kg of body fat. The average total DDT content was 21.8+/-2.9 mg/kg, of which 45.9% was DDE. The average...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract:PROBLEM:In 1999, a tuberculosis (TB) crisis was declared in the Western Pacific Region. APPROACH:In response, WHO established the Stop TB Special Project, which sought to halve 2000 levels of TB prevalence and mortality by 2010 through first reaching the global 2005 TB targets. LOCAL SETTING:Particular issues in the ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.038521
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To determine the direct medical costs of type 1 diabetes mellitus (T1DM) to the National Brazilian Health-Care System (NBHCS) and quantify the contribution of each individual component to the total cost. METHODS:A retrospective, cross-sectional, nationwide multicentre study was conducted between 2008 and 201...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,多中心研究
doi:10.2471/BLT.12.110387
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential effects of betel quid chewing on mortality. (A quid consists of betel nut, wrapped in betel leaves; tobacco is added to the quid by some users). METHODS:Prospective data were available on 20 033 individuals aged 18-75 years, living in Araihazar, Bangladesh. Demographic and exposure ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.149484
更新日期:2015-10-01 00:00:00
abstract::Studies have recently been published of surveys of antibodies to common respiratory viruses in human sera from several parts of the world. The present article reports the findings of a survey of antibodies to two more viruses (adenovirus type 8 and coxsackievirus type A21) in human sera mainly collected from six widel...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract:OBJECTIVE:To analyse national data on asbestos use and related diseases in the European Region of the World Health Organization (WHO). METHODS:For each of the 53 countries, per capita asbestos use (kg/capita/year) and age-adjusted mortality rates (deaths/million persons/year) due to mesothelioma and asbestosis were ca...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.13.132118
更新日期:2014-11-01 00:00:00
abstract::A description is given of laboratory and field trials with a new molluscicide, Bayer 73. Following successful laboratory trials at one part per million, a river containing much vegetation and many semi-stagnant pools was treated at this dosage, the application resulting in a complete disappearance of snails and eggs f...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::Reported are the results of a study to investigate the immunogenicity of oral poliovirus vaccine (OPV) when administered in mass campaigns compared with that following routine immunization programmes. For this purpose, paired sera were collected from a cohort of children before and after a mass vaccination with OPV in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Manpower projections for oral health are generally held to be more accurate than those for other health sectors since the diseases involved and their treatment times can be predicted more precisely. Nevertheless most oral health manpower projections are either overestimates or are not in line with the resources of ind...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Up-to-date information is given on the epidemiological situation of zoonotic visceral leishmaniasis (ZVL) in nine Mediterranean countries, and on drug regimens adopted in the management of ZVL patients in each country. Results of experimental and clinical trials on the efficacy and tolerability of liposomal amphoteric...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1995-01-01 00:00:00
abstract::In the early summer of 1993, an outbreak of Rift Valley fever (RVF) was reported among both humans and animals in Aswan Governorate, Upper Egypt. To determine whether RVF infection had spread to the Nile delta region of the country, we carried out a cross-sectional survey of 1181 occupationally exposed abattoir worker...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The ParaSight(R)-F test is a qualitative diagnostic test of Plasmodium falciparum, which is based on the detection by a monoclonal antibody of a species-specific soluble antigen (histidine-rich protein (HRP-II)) in whole blood and which can be performed without special equipment. A visual reading is given by a polyclo...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-01-01 00:00:00
abstract::This chapter presents the findings arrived at by applying the resource allocation model to tuberculosis control in the Republic of Korea. Optimum subprogrammes are obtained for the four objectives of the programme: reduction of disability, impairment, excess mortality, and economic loss. These subprogrammes are discus...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Structural quality is a key element in the quality of care provided at the primary level, which aims to offer health care interventions of proven efficacy. This assessment of the structural quality of Tanzanian primary health services indicated serious weaknesses in the available physical infrastructure, as well as su...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::A meeting was held to outline a comprehensive research plan, based on recent advances in biomedical sciences, for the development of improved methods for the control of tuberculosis. Such a plan requires a stepwise approach. The meeting focused on the initial activities to be carried out and on setting priorities.In t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:To increase case-finding of infection with human immunodeficiency virus (HIV) in Zambia and their referral to HIV care and treatment by supplementing existing client-initiated voluntary counselling and testing (VCT), the dominant mode of HIV testing in the country. METHODS:Lay counsellors offered provider-in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.084442
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To measure the socioeconomic inequality in infant mortality in Iran (the Islamic Republic of Iran). METHODS:We analysed data from the provincially representative Demographic and Health Survey, which was done in Iran in 2000. We used a dichotomous hierarchical ordered probit model to develop an indicator of s...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862005001100013
更新日期:2005-11-01 00:00:00
abstract::The effect of Plasmodium falciparum infection on the response to immunization with tetanus toxoid in pregnancy is of importance because malaria is more frequent and severe in pregnant women. This paper presents the results of a study in west Kenya of the antibody response to an adsorbed tetanus toxoid in primigravidae...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The paper presents clinical observations on 1 233 persons with smallpox who were admitted to the Infectious Diseases Hospital, Calcutta, in 1973. The disease was of the modified type in 53 patients (4.3%), the ordinary type in 717 (58.2%), the flat type in 249 (20.2%), and the haemorrhagic type in 214 (17.3%). The fat...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::The author reviews the agricultural use of night-soil, sewage, and sewage sludge from two points of view: the purely agricultural and the sanitary.Knowledge of the chemistry and bacteriology of human faecal matter is still rather scant, and much further work has to be done to find practical ways of digesting night-soi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1954-01-01 00:00:00
abstract::In order to study the role of genetic factors in susceptibility to leprosy infection, the prevalence of leprosy in 118 pairs of Burmese villages different distances apart was investigated. The distribution pattern of the correlation coefficients for leprosy rates was compared with that known to occur for genetic marke...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Several laboratories have reported a large number of plasmodial antigens that may be implicated in the immune-mediated protection against the asexual blood stage of Plasmodium falciparum. In order to establish relationships between the antigens reported by different laboratories, a comparative testing of 37 antibody r...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:Objective:To estimate population-wide hepatitis B and C seroprevalence using dried blood spot samples acquired for human immunodeficiency virus (HIV) surveillance as part of the 2010-2011 Demographic and Health Survey in Burkina Faso. Methods:We used the database acquired during the multistage, clustered, population-b...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.18.208603
更新日期:2018-11-01 00:00:00
abstract::As stocks of the first International Standard for Chorionic Gonadotrophin were running low, the WHO Expert Committee on Biological Standardization authorized the National Institute for Medical Research, London, in 1960 to proceed with arrangements to replace it. This paper describes the nature and handling of the prop...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::A study spanning 10 years indicates that the erythrocytic stages of malarial parasites can be stored indefinitely in the vapour phase of liquid nitrogen without significant loss of infectivity. The results also suggest that loss due to the recovery procedures exceeds any loss that may have occurred during freezing and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:To characterize patent and proprietary medicine vendors and shops in Nigeria and to assess their ability to help improve access to high-quality, primary health-care services. METHODS:In 2013 and 2014, a census of patent and proprietary medicine shops in 16 states of Nigeria was carried out to determine: (i) ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.154666
更新日期:2016-04-01 00:00:00
abstract::Few experiments have been reported on immunity to reinfection in domestic stock. The degree of resistance to reinfection with S. mattheei was studied in cattle and sheep. On the basis of the results, the only evidence of acquired immunity in calves and sheep is a reduction in the length of adult worms. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00