Abstract:
:Agglutinating antibodies produced in an adult rabbit in response to intravenous injections of live Leptospira sp. (serotype biflexa, strain Waz), consisted of a 19S component (present at day 6 after inoculation) and a 7S component (present at day 6 after inoculation). Both 19S and 7S antibodies persisted in the serum until the conclusion of the observations (day 216). The 19S antibody was completely destroyed by 2-mercaptoethanol but the 7S antibody was only partially sensitive to 2-mercaptoethanol.The serum proteins present in the 19S and 7S serum fractions were determined by immunoelectrophoresis and cellulose acetate electrophoresis. Elution of the serum components from cellulose acetate membranes directly confirmed that the beta-migrating IgM was the 19S serum component with leptospiral agglutinating activity and that gamma-migrating IgG was the 7S serum component with antileptospiral agglutinating activity.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Graves S,Faine Ssubject
Has Abstractpub_date
1970-01-01 00:00:00pages
579-87issue
4eissn
0042-9686issn
1564-0604journal_volume
43pub_type
杂志文章abstract:OBJECTIVE:To examine the impact of maternity waiting homes on the use of facility-based birthing services for women in two remote districts of Timor-Leste. METHODS:A before-and-after study design was used to compare the number of facility-based births in women who lived at different distances (0-5, 6-25, 26-50 and > 5...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.11.088955
更新日期:2012-02-01 00:00:00
abstract::This paper presents estimates of the prevalence of visual impairment and its causes in 2002, based on the best available evidence derived from recent studies. Estimates were determined from data on low vision and blindness as defined in the International statistical classification of diseases, injuries and causes of d...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862004001100009
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To investigate a new approach to calculating cause-related standardized mortality rates that involves assigning weights to each cause of death reported on death certificates. METHODS:We derived cause-related standardized mortality rates from death certificate data for France in 2010 using: (i) the classic me...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.16.172189
更新日期:2016-12-01 00:00:00
abstract::Recent studies with the indirect haemagglutination test for malaria are reviewed. Aspects of methodology, reproducibility, specificity, and sensitivity are discussed. A procedure is presented for application in the field, which indicates some progress towards developing a simple field method for the epidemiological su...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::The frequency of man-biting by mosquitos depends upon the amount of contact between man and mosquito, which in turn depends upon the behaviour patterns of both. In order to examine these relationships in an area with a high incidence of malaria, a study was made in 1965 of the nocturnal movements and of mosquito bitin...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::As in an earlier study, the authors have endeavoured to review the world incidence of poliomyelitis on the basis of the available statistical information (official notifications of cases and deaths) and to compare these data with data received from various sources regarding the prevailing viruses.It is certainly not y...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::Bringing together various disease-specific guidelines for sick children, WHO and UNICEF have developed an Integrated Management of Childhood Illness (IMCI) algorithm, one component of which (assess and classify) was tested in the outpatient department of a rural district hospital in western Uganda. Children aged 2-59 ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Although trench fever appears to be endemic in many areas of the world, recognition of the disease has been handicapped by the difficulties of making a clinical diagnosis and the unavailability of a simple laboratory procedure to establish the etiology. The author describes a method for the in vitro cultivation of Ric...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract::Despite the rising burden of noncommunicable diseases, access to quality decentralized noncommunicable disease services remain limited in many low- and middle-income countries. Here we describe the strategies we employed to drive the process from adaptation to national endorsement and implementation of the 2016 Botswa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.18.221424
更新日期:2019-02-01 00:00:00
abstract::The alpha antitoxin contents of the International Reference Preparations of Clostridium welchii Types B and D Antitoxins were assayed against two type A test toxins-Cl. welchii (perfringens) test toxin P2, issued by the Statens Seruminstitut, Copenhagen, and Cl. welchii test toxin AGX 1373, issued by the Wellcome Rese...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::The knowledge that domestic cats were susceptible to infection with freshly isolated A/Hong Kong/68 influenzavirus led to studies on the susceptibility of some other animal species to this virus, as well as to studies on the ability of egg-passaged Hong Kong virus and an Asian virus to infect cats. The ability of a re...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::Four cases of Plasmodium ovale malaria are reported among US servicemen stationed in Viet-Nam between January 1966 and March 1969. Taken together with other cases cited by the authors, these provide strong evidence of the existence (sometimes disputed) of this Plasmodium in continental South-East Asia.None of the men ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract::A method of assessing "atherosclerosis", if used according to certain rules, was shown in an earlier study to be capable of discriminating between groups of aortas or coronary arteries according to the quantity of certain defined lesions. It would not measure absolute amounts, but would show whether one group of speci...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract:OBJECTIVE:To describe mortality from neglected tropical diseases (NTDs) in Brazil, 2000-2011. METHODS:We extracted information on cause of death, age, sex, ethnicity and place of residence from the nationwide mortality information system at the Brazilian Ministry of Health. We selected deaths in which the underlying c...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.152363
更新日期:2016-02-01 00:00:00
abstract::Marion Koopmans tells Fiona Fleck why the world needs a publicly-funded network of hubs in all regions with local experts able to respond to infectious disease threats as they emerge. ...
journal_title:Bulletin of the World Health Organization
pub_type: 传,历史文章,新闻
doi:10.2471/BLT.18.030218
更新日期:2018-02-01 00:00:00
abstract::The haemagglutination-inhibition test has been used to assess the frequency of arbovirus infections in the population of Ceylon, by age-group, and also in some animals. The antigens used were: chikungunya, JE, dengue 1, 2, 3, 4, and Tahyna.The percentage of positive reactors to the group-B viruses ranged from 16.3% to...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1969-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the screening measures that would have been required to assess all travellers at risk of transporting A(H1N1)pdm09 out of Mexico by air at the start of the 2009 pandemic. METHODS:Data from flight itineraries for travellers who flew from Mexico were used to estimate the number of international air...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.12.114777
更新日期:2013-05-01 00:00:00
abstract::A test for monkeypox-specific antibodies is described. Monkeypox immune sera can be made type-specific by immunoabsorption with heterotypic poxvirus extracts. Monkeypox-specific antibodies were demonstrated in sera from 9 cynomolgus monkeys (Macaca fascicularis) that had previously been experimentally infected with mo...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Few experiments have been reported on immunity to reinfection in domestic stock. The degree of resistance to reinfection with S. mattheei was studied in cattle and sheep. On the basis of the results, the only evidence of acquired immunity in calves and sheep is a reduction in the length of adult worms. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1974-01-01 00:00:00
abstract::Representatives of the WHO influenza programme recently proposed a standard method of determining neuraminidase activity and neuraminidase inhibition (NI) antibody titres. Logit transformation of the data obtained with the WHO method for the NI assay permits a more efficient performance of the test and easy calculatio...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Field trials of various molluscicides-notably sodium pentachlorophenate, copper sulfate and dinitro-o-cyclohexylphenol-were carried out in Brazil in order to test their effectiveness against the aquatic intermediate hosts of human bilharziasis. Sodium pentachlorophenate was found to be the most effective in relation t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1958-01-01 00:00:00
abstract::Airport and aviation authorities are starting to recognize that airports do not have to be unhealthy. Sima Barmania reports. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.18.020818
更新日期:2018-08-01 00:00:00
abstract::A new straightforward photometric method for the assay of the antimalarial drug chloroquine and its metabolites in urine is described. The method involves an ion-pair extraction procedure with dichloromethane using the acid-base indicator bromthymol blue as counter-ion. The ion pair formed with chloroquine in the orga...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::A simple technique for achieving high yields of Plasmodium falciparum parasites on a continuous basis is described. The technique is applicable in any laboratory. The culture apparatus is also simple and inexpensive and allows multiple cultures to be run simultaneously. A total of approximately 1-2 x 10(9) parasites c...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The author examines in detail the symptomatology, diagnosis, and treatment of plague, and outlines the problem of the length of the incubation period.The clinical features commonly met with in all severely-affected plague patients, regardless of the primary localization of the infection, are described. The author then...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract::Few widespread diseases show such marked local differences in community patterns as does trachoma; these differences occur not only in over-all prevalence but also in the mean age at onset, the age distribution of the evolutive stages and the role of associated infections. These are among the factors which determine t...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1968-01-01 00:00:00
abstract::For several years after the First World War calcium oxide was the main compound used in the control of Oncomelania nosophora in Japan. This was generally replaced in 1944 by calcium cyanamide; since 1952 the prefectural authorities in areas of endemic bilharziasis have increasingly turned to the use of sodium pentachl...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::Current transportation policies in mega-cities worldwide lead to major threats to health through traffic injuries, air pollution, noise, reduction in physical activities, and adverse impact on urban quality of life. In addition, a large section of the population in cities in low-income countries has to live in informa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Rosa Moreira tells Andréia Azevedo Soares how Angola reined in its worst yellow fever epidemic in 30 years. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.16.031016
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Literature on human resources for health in Africa has focused on personal health services. Little is known about graduate public health education. This paper maps "advanced" public health education in Africa. Public health includes all professionals needed to manage and optimize health systems and the public...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.07.045526
更新日期:2007-12-01 00:00:00