Reevaluation of C-reactive protein in cancer sera by radioimmunoassay and radial immunodiffusion. I. Diagnostic value and use in battery of conventional tumor markers.

abstract：OBJECTIVE:Esophagogastric cancer occurs more frequently in older patients, but these are underrepresented in clinical studies establishing the current treatment standards for perioperative chemotherapy in locally advanced disease. This leads to uncertainty regarding the treatment of older patients with potentially toxi...

journal_title：Oncology

authors： Haag GM,Byl A,Jäger D,Berger AK

更新日期：2017-01-01 00:00:00

abstract：:Lewis lung carcinoma (3LL), which has been most frequently used for various investigations of cancer, was converted to an ascitic form designated 3LL-SA. Ascites tumor cells showed a mixed population of single cells and about 10% islands which were made up of 2 to about 50 cells. Transplantability was 100%. The biolog...

journal_title：Oncology

authors： Sato T,Takusagawa K,Asoo N,Kumano N,Hasuike M,Konno K

更新日期：1989-01-01 00:00:00

abstract：:Mice of four different inbred strains (CBA, Balb/c, C57Bl/6 and DBA/2), bearing different transplanted tumours (methylcholanthrene-induced sarcomas, B16 melanoma and P-815 mastocytoma), were tested for cellular immune reactivity to the synthetic encephalitogenic peptide of human myelin basic protein by the leucocyte a...

journal_title：Oncology

authors： Yong WK,Halliday WJ

更新日期：1983-01-01 00:00:00

abstract：:We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion ...

journal_title：Oncology

authors： Thuleau A,Gilbert C,Bauër P,Alran S,Fourchotte V,Guillot E,Vincent-Salomon A,Kerihuel JC,Dugay J,Semetey V,Kriegel I,Fromantin I

更新日期：2019-01-01 00:00:00

abstract：:Primary pancreatic lymphoma (PL) is an extremely rare disease, and large-scale studies are rarely performed even in Western countries, in which all cases of PL reported to date were of the B-cell type. Little information regarding PL is available in Japan. Nineteen cases of PL were collected through a nationwide study...

journal_title：Oncology

authors： Nishimura R,Takakuwa T,Hoshida Y,Tsujimoto M,Aozasa K

更新日期：2001-01-01 00:00:00

abstract：:The diagnostic imaging of hepatocellular carcinoma (HCC) has recently undergone marked progress. The advent of the ultrasound (US) contrast agent Sonazoid, approved in January 2007, and magnetic resonance imaging (MRI) with the liver-specific MRI contrast agent gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic ac...

journal_title：Oncology

authors： Kudo M

更新日期：2011-01-01 00:00:00

abstract：:Capecitabine is converted to 5-fluorouracil by thymidine phosphorylase, and mitomycin C is capable of upregulating the expression of thymidine phosphorylase suggesting a synergistic effect. Fifty-three patients (median age 62 years) with anthracycline- and taxane-resistant, metastatic breast cancer received mitomycin ...

journal_title：Oncology

authors： Massacesi C,La Cesa A,Marcucci F,Pilone A,Rocchi MB,Zepponi L,Santini D,Tonini G,Burattini L

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown. METHODS:We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, at...

journal_title：Oncology

authors： Di Lorenzo G,Buonerba L,Ingenito C,Crocetto F,Buonerba C,Libroia A,Sciarra A,Ragone G,Sanseverino R,Iaccarino S,Napodano G,Imbimbo C,Leo E,Kozlakidis Z,De Placido S

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Our aim is to assess the clinicopathological significance of E-cadherin and beta-catenin expression, as well as their association with apoptosis in gallbladder cancers. METHODS:The expression of E-cadherin and beta-catenin proteins was examined in 4 biliary tract cancer cell lines and 49 gallbladder cancer s...

journal_title：Oncology

authors： Hirata K,Ajiki T,Okazaki T,Horiuchi H,Fujita T,Kuroda Y

更新日期：2006-01-01 00:00:00

abstract：:A unique case of multiple keratoacanthomas is described, with involvement of the face and lower extremities with persistent lesions clinically and histologically diagnostic of keratoacanthomas. The lower extremity lesions appear as giant keratoacanthomas, with evolution into a distinctive confluent plaque. This import...

journal_title：Oncology

authors： Schwartz RA

更新日期：1979-01-01 00:00:00

abstract：:The aim of this study is to compare the levels of carcinoembryonic antigen (CEA) in the gastric juice, stomach mucosa and plasma of gastrectomy patients at risk of developing cancer with those in normal controls and gastric cancer subjects. Blood samples, gastric juices and biopsy material were taken from 52 patients ...

journal_title：Oncology

authors： Castelli M,Guadagni S,Bagnato A,Pistoia MA,Carboni M,Sega E

更新日期：1986-01-01 00:00:00

abstract：:We have provided an in-depth, longitudinal, clinical/genetic/pathologic investigation of a family consonant with the sarcoma, breast cancer and brain tumors, lung and laryngeal cancer, leukemia, lymphoma, and adrenalcortical carcinoma syndrome. The pattern of cancer expression involves all three germinal layers with t...

journal_title：Oncology

authors： Lynch HT,Radford B,Lynch JF

更新日期：1990-01-01 00:00:00

abstract：:Fourteen patients with disseminated breast cancer with primary or secondary resistance to tamoxifen were treated with LY156758. There were no complete or partial responses and 1 patient showed a minor response. These data illustrate that LY156758 did not have significant antitumor activity in patients previously treat...

journal_title：Oncology

authors： Buzdar AU,Marcus C,Holmes F,Hug V,Hortobagyi G

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:In order to determine whether infection with Helicobacter pylori might be associated with pancreatic adenocarcinoma, we performed a study to compare the H. pylori seroprevalence rate between patients with pancreatic carcinoma and matched control subjects. PATIENTS AND METHODS:Blood samples from 92 patients wit...

journal_title：Oncology

authors： Raderer M,Wrba F,Kornek G,Maca T,Koller DY,Weinlaender G,Hejna M,Scheithauer W

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of percutaneous cementoplasty for painful bone metastasis from hepatocellular carcinoma (HCC). METHODS:Cementoplasty was performed for 22 metastatic bone tumors in 13 patients. All patients had intractable pain and were diagnosed as metastatic bone tumor from HCC. The ostyneedle was in...

journal_title：Oncology

authors： Kodama H,Aikata H,Uka K,Takaki S,Mori N,Waki K,Jeong SC,Kawakami Y,Shirakawa H,Takahashi S,Toyota N,Ito K,Chayama K

更新日期：2007-01-01 00:00:00

abstract：:Inhibitors of polyamine synthesis were tested for therapeutic effectiveness on transplantable prostate cancer. Inhibition of either ornithine decarboxylase or S-adenosyl-L-methionine decarboxylase (AMDC) by alpha-difluormethylornithine (DFMO) or methylglyoxal-bis[guanylhydrazone] (MGBG), respectively, was associated w...

journal_title：Oncology

authors： Dunzendorfer U,Relyea NM,Kleinert E,Balis ME,Whitmore WF Jr

更新日期：1983-01-01 00:00:00

abstract：:The association of MMP-2 (matrix metalloproteinase 2, 72-kD collagenase IV) with invasive and metastatic capacity of tumor cells has implicated a potential role in the prognosis for cancer patients. However, no larger study has been done to prove this hypothesis. The present study was therefore designed to investigate...

journal_title：Oncology

authors： Allgayer H,Babic R,Beyer BC,Grützner KU,Tarabichi A,Schildberg FW,Heiss MM

更新日期：1998-03-01 00:00:00

abstract：:The present communication reports the inhibitory action of aminoglutethimide on 9,10-dimethyl-1,2-benzanthracene (DMBA) induced mammary carcinogenesis in virgin female Holtzman rats. When 20 mg of DMBA is given to the rats and maintained on normal diet for 32 weeks, approximately 70% of the animals develop mammary tum...

journal_title：Oncology

authors： Rao AR,Das MG,Das P

更新日期：1985-01-01 00:00:00

abstract：:The best treatment for primary gastric lymphomas (PGL) has not yet been defined. Eighty-three patients with stage I/II PGL are documented, focusing on prognostic factors, treatment-related morbidity and mortality, and therapeutic outcome. Chemotherapy improved survival in comparison to local treatments, i.e. gastrecto...

journal_title：Oncology

authors： Ferreri AJ,Cordio S,Paro S,Ponzoni M,Freschi M,Veglia F,Villa E

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:Diamine oxidase (DAO) is an enzyme that catalyzes oxidation and is highly active in the mature upper villus cells of the intestinal mucosa. This study sought to evaluate plasma DAO activities during adjuvant chemotherapy in patients with gastric cancer. METHODS:We investigated 20 patients with gastric cance...

journal_title：Oncology

authors： Namikawa T,Fukudome I,Kitagawa H,Okabayashi T,Kobayashi M,Hanazaki K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The tumor suppressor gene p53 is a nuclear protein which plays a key role in tumor progression by regulating DNA repair, cell division and apoptosis. One major function of wild-type p53 is to control the onset of DNA replication at the G1-S boundary by inducing p21 protein, which promotes cell cycle arrest b...

journal_title：Oncology

authors： Okuyama T,Maehara Y,Kabashima A,Takahashi I,Kakeji Y,Sugimachi K

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:In order to broaden the possibility for anti-MAGE-3 immune targeting, it is important to identify HLA-A24-restricted epitopes derived from MAGE-3, since HLA-A24 is one of the most common alleles in Japanese and Asian people. In the present study, we defined a new MAGE-3 derived, HLA-A24-binding peptide presente...

journal_title：Oncology

authors： Miyagawa N,Kono K,Mimura K,Omata H,Sugai H,Fujii H

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the efficacy and safety of bolus 5-fluorouracil (5-FU) and leucovorin combined with weekly paclitaxel (FLTAX) in advanced gastric cancer (GC) patients. METHODS:Patients with untreated stage IV GC received paclitaxel 80 mg/m(2) as a 1-hour infusion, followed by 5-FU 600 mg/m(2) as a bolus infusio...

journal_title：Oncology

authors： Matsubara J,Shimada Y,Kato K,Nagai Y,Iwasa S,Nakajima TE,Hamaguchi T,Yamada Y,Takagi S,Kobayashi K,Yoshioka A,Nakayama N,Tsuji A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Pegylated liposomal doxorubicin (PLD) and capecitabine (CAP) have separately shown significant antitumor activity in a wide range of solid tumors. A phase I study was conducted in order to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of their combination in patients with refr...

journal_title：Oncology

authors： Maltezos E,Amarantidis K,Trichas M,Vasiliadis M,Toromanidou M,Chatzaki E,Karayiannakis A,Tsaroucha A,Romanidis K,Kakolyris S

更新日期：2005-01-01 00:00:00

abstract：:An increase in serum iron levels and a decrease in serum unsaturated iron binding capacity (uIBC) were noted following the administration of cisplatinum to 9 children with malignancies. The mean serum iron concentration increased from a pretreatment level of 75.7 +/- 30.5 micrograms/ml to a posttreatment level of 162....

journal_title：Oncology

authors： Kletter G,Parks BR Jr,Bhatnagar A,Iyer RV

更新日期：1988-01-01 00:00:00

abstract：:Recombinant human granulocyte colony-stimulating factor (G-CSF) has been used worldwide in cancer patients for over 1 year, and (only 5 years from the first publication on the clinical use of this growth factor) experience is rapidly accumulating in many oncological situations. Several randomized studies have confirme...

journal_title：Oncology

authors： Bronchud MH

更新日期：1994-03-01 00:00:00

abstract：:The priming action of estradiol and the antiestrogen tamoxifen (TMX) on progesterone receptor (PgR) synthesis has been investigated in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor model testing different priming times. Rats received either TMX or estradiol benzoate (E2B) for 3 or 7 days. Tumors were as...

journal_title：Oncology

authors： Boccardo F,Cerruti G,De Menech R,Valenti G,Zanardi S

更新日期：1987-01-01 00:00:00

abstract：:This paper reviews the effectiveness of local interleukin-2 (IL-2) therapy and its effector induction mechanisms in vivo. Local therapy with IL-2 and/or lymphokine-activated killer (LAK) cells is associated with far fewer side effects than systemic treatment. Local infusions of IL-2 into malignant pleural effusions an...

journal_title：Oncology

authors： Sone S,Ogura T

更新日期：1994-03-01 00:00:00

abstract：PURPOSE:To define the cyclophosphamide (CTX) maximal tolerated dose when combined with fixed doses of gemcitabine, fluorouracil (5-FU) and folinic acid (leucovorin, LFA) in metastatic breast cancer patients pretreated with anthracyclines and taxanes. METHODS:Metastatic breast cancer patients aged < or = 75 years, with...

journal_title：Oncology

authors： Frasci G,D'Aiuto G,Comella P,Thomas R,Capasso I,Botti G,Cortino GR,Di Bonito M,Rubulotta R,Vallone P,Comella G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for differentiating benign from malignant lesions, evaluating tumor stage, monitoring the response to therapy and detecting tumor recurrence in a variety of malignancies. Nevertheless, its use in patients with hepatocellular carcinoma (H...

journal_title：Oncology

authors： Yoon KT,Kim JK,Kim DY,Ahn SH,Lee JD,Yun M,Rha SY,Chon CY,Han KH

更新日期：2007-01-01 00:00:00