Evaluation of carcinoembryonic antigen levels in gastric juice, stomach mucosa and plasma in high-risk and gastric cancer patients.

abstract：:The activities of established and experimental antitumor drugs were tested against the BRO and MeWo human melanomas transplanted in the subrenal capsule of phenotypically immunocompetent (CBA x C57BL/6)F1 mice. Immunosuppression was achieved with preliminary whole-body radiation, and cytological examination showed tha...

journal_title：Oncology

authors： Ryabkova VI,Lockshin A,Strukov IG,Sokolova VK

更新日期：1994-11-01 00:00:00

abstract：:Pretreatment serum levels of squamous cell carcinoma (SCC)-antigen as determined with a polyclonal and monoclonal antibody-based assay were determined in 136 patients with invasive mammary carcinoma, 8 patients with ductal carcinoma in situ and 23 patients with benign breast diseases. For the polyclonal assay, the ove...

journal_title：Oncology

authors： Wobbes T,Thomas CM,Segers MF

更新日期：1990-01-01 00:00:00

abstract：:We have measures serial carcinoembryonic antigen (CEA) titers in 92 patients, randomly selected from the patient population of a Radiotherapeutic Clinic, to correlate with clinical and follow-up evaluation. 57 out of 92 patients had positive CEA levels (2.5 ng/ml) or 62 percent of proven cancer patients. In this serie...

journal_title：Oncology

authors： Vider M,Kashmiri R,Hunter L,Moses B,Meeker WR,Utley JF,Maruyama Y

更新日期：1974-01-01 00:00:00

abstract：:The relationship of vitamins to cancer is very complex. Three types of interactions are possible: the effect of vitamins on tumor growth, the effect of tumors on vitamin metabolism, and the effect of vitamins on chemical carcinogens and anti-tumor chemotherapeutic agents. The significance of vitamins with particular r...

journal_title：Oncology

authors： Basu TK

更新日期：1976-01-01 00:00:00

abstract：:A transplantable transitional cell murine bladder tumor induced by N-[4-(5-nitro-2-furyl)-thiazolyl] formamide (FANFT) was characterized by tumor growth, survival time and response to chemotherapy drugs, cis-dichloro-trans-dihydroxy-bis-iso-propylamine platinum IV (CHIP), cis- diaminedichloro platinum II (DDP), cyclop...

journal_title：Oncology

authors： Murphy GP,Pontes JE,Williams PD

更新日期：1984-01-01 00:00:00

abstract：:The newly isolated phenylpropanoids syringin, syringenin-apiosylglucoside, eleutheroside E and the high molecular lectins and viscotoxins were selected for a standardization of mistletoe extracts and drug preparation. The phenylpropanoids found in all alcoholic and aqueous extracts were suitable for an HPLC fingerprin...

journal_title：Oncology

authors： Wagner H,Jordan E,Feil B

更新日期：1986-01-01 00:00:00

abstract：:72 patients with advanced malignant lymphoma resistant to standard chemotherapy were treated with 1-(2-chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU) at 130 mg/m2 orally every six weeks. Objective responses were noted in 13 of 39 evaluable patients with Hodgkin's disease, three of 15 patients with lymphocytic lymphoma...

journal_title：Oncology

authors： Stolinsky DC,Solomon J,Weiner JM,Bateman JR

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVES:We recently demonstrated that papillary microcarcinomas with preoperatively detectable node metastasis in the lateral compartment on ultrasonography (clinically apparent metastasis) show worse postoperative relapse-free survival than those with no metastasis or metastasis that could not be detected preoperat...

journal_title：Oncology

authors： Ito Y,Uruno T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Kuma K,Miyauchi A

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Our aim was to assess FDG-PET/CT as a surrogate biomarker of the pathological complete response in locally advanced rectal cancer treated with neoadjuvant chemoradiation. METHODS:T3-4 and/or N+ rectal cancer patients were treated prospectively with capecitabine-based chemoradiation and total mesorectal exci...

journal_title：Oncology

authors： Bampo C,Alessi A,Fantini S,Bertarelli G,de Braud F,Bombardieri E,Valvo F,Crippa F,Di Bartolomeo M,Mariani L,Milione M,Biondani P,Avuzzi B,Chiruzzi C,Pietrantonio F

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Breast cancer (BC) is the most frequent female carcinoma and the major cause of death in women aged 35--50 years. The total number of patients surviving BC and especially the morbidity rate of patients below the age of 55 years has increased significantly in the last several years. As a consequence, the number ...

journal_title：Oncology

authors： Beckmann MW,Jap D,Djahansouzi S,Nestle-Krämling C,Kuschel B,Dall P,Brumm C,Bender HG

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The phosphatidylinositol 3-kinase (PI3K) pathway plays a critical role in ovarian cancer cell survival and proliferation. The aim of this study was to determine whether the suppression of the PI3K catalytic subunit p110alphainhibits the growth of ovarian cancer cells in vitro and in vivo. METHODS:The short h...

journal_title：Oncology

authors： Zhang X,Deng HX,Zhao X,Su D,Chen XC,Chen LJ,Wei YQ,Zhong Q,Li ZY,He X,Yi T

更新日期：2009-01-01 00:00:00

abstract：:To evaluate the influence of delay between first symptom and first treatment upon survival the medical records of 596 patients with breast cancer were reviewed. The following intervals were considered: less than 3 months; 3-6 months and greater than 6 months. Patients in the less than 3 months delay group had a better...

journal_title：Oncology

authors： Machiavelli M,Leone B,Romero A,Perez J,Vallejo C,Bianco A,Rodriguez R,Estevez R,Chacon R,Dansky C

更新日期：1989-01-01 00:00:00

abstract：:Cases are presented in which 111In-bleomycin accumulated in Virchow's gland metastasis from squamous cell carcinoma of the uterine cervix, and in paratracheal lymphatic gland metastasis from embryonal carcinoma of the right ovary. Thus, this radiopharmaceutical was found to be of great use for assessment of metastatic...

journal_title：Oncology

authors： Kida T,Ikeda M

更新日期：1986-01-01 00:00:00

abstract：:Liver is involved in about 5-8% of newly diagnosed Hodgkin's disease (HD) cases. The incidence reaches up to 50-60% in postmortem studies. In the literature only a few cases of idiopathic cholestatic jaundice have been described without an apparent cause and a paraneoplastic etiology has been suggested. We report 2 ca...

journal_title：Oncology

authors： Yalçin S,Kars A,Sökmensüer C,Atahan L

更新日期：1999-07-01 00:00:00

abstract：:A model system for studying some aspects of the interaction of cancer cells in tumors and their surrounding nonmalignant tissue is the co-culture of cancer cells and embryonic chick neural retinal cells in gyratory shakers. Neural retina cell aggregation, under these conditions, has been shown to be differentially inh...

journal_title：Oncology

authors： Maslow DE,Mayhew E,Mittleman A

更新日期：1981-01-01 00:00:00

abstract：:Primary fetal rat fibroblasts (FRF cells) were transfected with DNA extracted from BKV-transformed hamster kidney cells at low passage after transformation (HKBKlp cells) and at high passage after transformation (HKBKhp cells). Two transformed rat cell lines were obtained, FRF-DNA-HKBKlp cells and FRF-DNA-HKBKhp cells...

journal_title：Oncology

authors： Possati L,Collesi A,Rosciani C,Rubini C

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:To evaluate the efficacy and toxicity of irinotecan and oxaliplatin plus 5-fluorouracil (FU) and leucovorin (FOLFIRINOX) as second-line therapy in metastatic pancreatic adenocarcinoma (MPA). PATIENTS AND METHODS:We retrospectively analyzed the medical records of 27 patients with MPA treated with FOLFIRINOX ...

journal_title：Oncology

authors： Assaf E,Verlinde-Carvalho M,Delbaldo C,Grenier J,Sellam Z,Pouessel D,Bouaita L,Baumgaertner I,Sobhani I,Tayar C,Paul M,Culine S

更新日期：2011-01-01 00:00:00

abstract：:Lonidamine alone or in combination with hyperthermic perfusion, with or without melphalan, was investigated in 12 patients with stage II, III, and IV malignant melanoma. The authors evaluated the most effective methods and sequence of Lonidamine administration. Preliminary results suggest that the highest effectivenes...

journal_title：Oncology

authors： Cavaliere R,Di Filippo F,Varanese A,Carlini S,Calabro A,Aloe L,Piarulli L

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Identification of high-risk stage II colorectal cancer (CRC) patients, potential candidates for adjuvant chemotherapy, is challenging. Current clinical guidelines rely mainly on histopathological markers with relatively weak prognostic value. This motivates further search for prognostic markers. METHODS:Thi...

journal_title：Oncology

authors： Dimberg J,Andersson RE,Haglund S

更新日期：2020-01-01 00:00:00

abstract：:Nucleophosmin/B23 is a nucleolar phosphoprotein which redistributes from nucleoli to nucleoplasm (B23-translocation) when cells are exposed to certain anticancer drugs, particularly intercalators. The B23-translocation assay has been demonstrated in cell culture to correlate with drug effects and to detect drug-resist...

journal_title：Oncology

authors： Finch RA,Chan PK

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:We investigated stanniocalcin 1 (STC 1) expression to assess its clinical utility as a blood marker in patients with gastric cancer and evaluated its biological impact in terms of tumor aggressiveness. METHODS:Blood specimens from 93 patients with gastric cancer and 21 normal healthy volunteers were assessed...

journal_title：Oncology

authors： Arigami T,Uenosono Y,Ishigami S,Hagihara T,Haraguchi N,Matsushita D,Yanagita S,Nakajo A,Okumura H,Hokita S,Natsugoe S

更新日期：2012-01-01 00:00:00

abstract：:We started a treatment trial for malignant pericardial tamponade with intracavitary oxytetracycline, 500-1,000 mg/day, administered via an indwelling pericardial cannula after extraction of as much pericardial fluid as possible. This procedure was repeated every 24 h for 6 consecutive days or until no more fluid could...

journal_title：Oncology

authors： Grau JJ,Estapé J,Palombo H,Roca M,Daniels M,Tarragó E,Viñolas N

更新日期：1992-01-01 00:00:00

abstract：:The cytochrome P450 CYP2D6 is a polymorphic drug-metabolizing enzyme that is involved in the metabolism of several drugs and xenobiotics. Several independent studies indicate that the CYP2D6 metabolic status is a secondary factor in the risk of developing lung cancer, with individuals with high activity being at incre...

journal_title：Oncology

authors： Agúndez JA,Gallardo L,Ledesma MC,Lozano L,Rodriguez-Lescure A,Pontes JC,Iglesias-Moreno MC,Poch J,Ladero JM,Benítez J

更新日期：2001-01-01 00:00:00

abstract：:Quercetin, a mutagenic but noncarcinogenic flavonoid, inhibited the increased incorporation of inorganic phosphate into phospholipids of human embryo fibroblasts induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter. Quercetin also inhibited TPA-induced increases of sugar transport and RNA syn...

journal_title：Oncology

authors： Nishino H,Nishino A,Iwashima A,Tanaka K,Matsuura T

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:To investigate the relationship between the histopathologic effects of preoperative chemoradiotherapy in rectal cancer and the proteins, proliferating cell nuclear antigen (PCNA) and p53. METHODS:Samples from 73 tumors were examined. The histopathologic effects observed in the resected specimens induced by ...

journal_title：Oncology

authors： Díez M,Ramos P,Medrano MJ,Mugüerza JM,Villeta R,Lozano O,Escribano J,Noguerales F,Ruíz A,Granell J

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To determine the dose-limiting toxicities (DLTs) and the maximum-tolerated doses of the paclitaxel, oxaliplatin (LOHP) and capecitabine combination in patients with advanced solid tumors. PATIENTS AND METHODS:Patients received escalating doses of paclitaxel (starting dose 100 mg/m2) and LOHP (starting dose 40 ...

journal_title：Oncology

authors： Saridaki Z,Bozionelou V,Kentepozidis N,Kotsakis A,Vardakis N,Kalykaki A,Gioulbasanis I,Karampeazis A,Vamvakas L,Georgoulias V,Mavroudis D

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:This phase II study examined the efficacy and safety of alternating regimens of mFOLFOX6 and FOLFIRI as a first-line treatment for unresectable or metastatic colorectal cancer. PATIENTS AND METHODS:Forty-eight patients were enrolled in this study. Patients received an alternating regimen of 4 cycles of mFOLF...

journal_title：Oncology

authors： Oki E,Emi Y,Akagi Y,Tokunaga S,Sadanaga N,Tanaka T,Ogata Y,Saeki H,Kakeji Y,Baba H,Nishimaki T,Natsugoe S,Shirouzu K,Maehara Y,Kyushu Study Group of Clinical Cancer.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Uveal melanoma primarily metastasizes hematogenously with metastases often confined to the liver. The aim of this study was to investigate the presence of circulating tumor cells (CTC) in patients with metastatic disease as a marker for systemic disease and to determine their prognostic relevance. METHODS:Bl...

journal_title：Oncology

authors： Schuster R,Bechrakis NE,Stroux A,Busse A,Schmittel A,Thiel E,Foerster MH,Keilholz U

更新日期：2011-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is characterized as a highly chemoresistant cancer with no effective systemic therapy. Despite surgical or locoregional therapies, prognosis remains poor because of high tumor recurrence or tumor progression, and currently there are no well-established effective adjuvant therapies. The m...

journal_title：Oncology

authors： Pang RW,Poon RT

更新日期：2007-01-01 00:00:00

abstract：:Oral cancer is the eleventh most common cancer globally, with well-established major risk factors of tobacco, areca nut, alcohol, and high-risk human papillomavirus (HR-HPV) types 16 and 18. HR-HPV16/18 are the etiologic agents of cervical cancers and a proportion of oropharyngeal cancers. HPV-associated oropharyngeal...

journal_title：Oncology

authors： Yete S,D'Souza W,Saranath D

更新日期：2018-01-01 00:00:00