Abstract:
:Liver is involved in about 5-8% of newly diagnosed Hodgkin's disease (HD) cases. The incidence reaches up to 50-60% in postmortem studies. In the literature only a few cases of idiopathic cholestatic jaundice have been described without an apparent cause and a paraneoplastic etiology has been suggested. We report 2 cases with HD presenting with obstructive jaundice without obvious liver involvement. The first case died soon after diagnosis; the second case received chemotherapy and radiotherapy, and she is well at 26 months' follow-up. Extrahepatic HD with intrahepatic cholestasis is an extremely rare situation without an established approach. Such cases like the present ones may help to understand the pathogenesis of the liver involvement of HD and determine the best management of these cases.
journal_name
Oncologyjournal_title
Oncologyauthors
Yalçin S,Kars A,Sökmensüer C,Atahan Ldoi
10.1159/000012005subject
Has Abstractpub_date
1999-07-01 00:00:00pages
83-5issue
1eissn
0030-2414issn
1423-0232pii
12005journal_volume
57pub_type
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