Increase of tryptophan and 5-hydroxyindole acetic acid in the brain of ornithine carbamoyltransferase deficient sparse-fur mice.

abstract：:The two pathways of de novo lecithin synthesis, choline incorporation (I) and phosphatidylethanolamine methylation (II), were examined in lung slices from rhesus monkey fetuses throughout the last half of gestation. Incorporation rates of pathway-specific radioactive precursors were used as a measure of lecithin produ...

journal_title：Pediatric research

authors： Epstein MF,Farrell PM

更新日期：1975-08-01 00:00:00

abstract：:Genetic variants of surfactant protein B (SP-B) have been associated with respiratory distress syndrome (RDS) in the prematurely born infant. We wished to determine linkage between RDS and SP-B single nucleotide polymorphisms (SNPs) [-18 (A/C), 1013 (A/C), 1580 (C/T), and 9306 (A/G)] or SP-B-linked microsatellite [(D2...

journal_title：Pediatric research

authors： Floros J,Thomas NJ,Liu W,Papagaroufalis C,Xanthou M,Pereira S,Fan R,Guo X,Diangelo S,Pavlovic J

更新日期：2006-04-01 00:00:00

abstract：:Carbohydrate and lipid intakes have both been found to modulate the metabolism of long-chain fatty acids. To define the respective influence of these two energy substrates on plasma fatty acid concentrations, 32 studies were performed in 16 parenterally fed newborn infants (mean +/- SEM, birth wt: 2.15 +/- 0.1 kg, age...

journal_title：Pediatric research

authors： Pineault M,Lepage G,Bisaillon S,Roy CC,Chessex P

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Short-bowel syndrome (SBS) is the most common cause of neonatal intestinal failure. Recovery requires intestinal adaptation, dependent on enteral nutrition (EN) and growth factors such as glucagon-like peptide-2 (GLP-2), which is secreted from L cells in the ileum. Neonatal SBS often results in loss of ileum...

journal_title：Pediatric research

authors： Hua Z,Turner JM,Sigalet DL,Wizzard PR,Nation PN,Mager DR,Ball RO,Pencharz PB,Wales PW

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Risk factors for diastolic dysfunction in hypertrophic cardiomyopathy (HCM) are poorly understood. We investigated the association of variants in hypoxia-response genes with phenotype severity in pediatric HCM. METHODS:A total of 80 unrelated patients <21 y and 14 related members from eight families with HC...

journal_title：Pediatric research

authors： Alkon J,Friedberg MK,Manlhiot C,Manickaraj AK,Kinnear C,McCrindle BW,Benson LN,Addonizio LJ,Colan SD,Mital S

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Subgaleal hemorrhage (SGH) is reported to be associated with severe hemodynamic instability, coagulopathy, and even mortality. The importance of the presence or absence of neonatal encephalopathy in predicting SGH outcomes has not been explored. The aim of this study was to determine the relationship of clin...

journal_title：Pediatric research

authors： El-Dib M,Parziale MP,Johnson L,Benson CB,Grant PE,Robinson J,Volpe JJ,Inder T

更新日期：2019-08-01 00:00:00

abstract：:We studied chloride efflux from isolated rabbit pancreatic acini in suspension, by loading with 36Cl to steady state and rapidly washing acini by filtration to determine 36Cl cpm/micrograms DNA remaining. Linear loss of acinar chloride occurred over 5 min (k = 0.038 +/- 0.008 min-1, n = 5). Forskolin (5 x 10(-5) M) in...

journal_title：Pediatric research

authors： Kopelman H,Gauthier C

更新日期：1991-06-01 00:00:00

abstract：:This study aimed to investigate 1) the plasma resistin concentration at birth, 2) the relationship of resistin with leptin and insulin, and 3) the association of resistin with anthropometric indexes in newborn infants. Blood samples for hormonal assay were obtained from preterm and term newborns within the first 2 h o...

journal_title：Pediatric research

authors： Ng PC,Lee CH,Lam CW,Chan IH,Wong E,Fok TF

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Infant adiposity is linked to both high maternal fat mass (FM) and excessive gestational FM gain, whereas the association with maternal adipokines is less clear. The aim was to determine how levels of maternal leptin, the soluble leptin receptor (sOB-R), adiponectin, and FM during pregnancy were linked to in...

journal_title：Pediatric research

authors： Andersson-Hall UK,Pivodic A,de Maré HK,Pernilla Svedin J,Carina Mallard E,Albertsson-Wikland KG,Holmäng AB

更新日期：2020-09-14 00:00:00

abstract：:The ventricular epicardial activation sequence (VEAS) in 15 anesthetized lambs (near term fetus to 3.5 months of age) was determined using 40 simultaneously recorded bipolar electrograms for each animal. Isochrone maps were drawn by hand using relative activation times determined from the maximum first derivative of m...

journal_title：Pediatric research

authors： Mathewson JW,Riemenschneider TA,Ruttenberg HD

更新日期：1977-01-01 00:00:00

abstract：:We banded the trachea of 4-wk-old male rats and studied lung growth, lung morphometry, and static pulmonary mechanics 4 wk later. We compared the experimental animals to sham-operated male littermates of the same age, 8-wk-old normal male littermates, and weight-matched rats of a younger age. Tracheal banded animals w...

journal_title：Pediatric research

authors： Kida K,Thurlbeck WM

更新日期：1981-03-01 00:00:00

abstract：:BackgroundPregnant women at a high risk of preterm delivery receive glucocorticoids to accelerate fetal lung maturation and surfactant synthesis. However, the effect of antenatal steroids on the developing diaphragm remains unclear. We hypothesized that maternal betamethasone impairs the fetal diaphragm, and the magni...

journal_title：Pediatric research

authors： Mahzabin T,Pillow JJ,Pinniger GJ,Bakker AJ,Noble PB,White RB,Karisnan K,Song Y

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Animal models have shown that insulin-like growth factor I (IGF-I) may mediate protein-induced kidney growth. Our aim was to analyze the effect of IGF-I on protein-induced kidney growth in healthy infants. METHODS:This is a secondary analysis of a randomized trial that compared growth of infants fed with a ...

journal_title：Pediatric research

authors： Luque V,Escribano J,Grote V,Ferre N,Koletzko B,Gruszfeld D,Socha P,Langhendries JP,Goyens P,Closa-Monasterolo R,European Childhood Obesity Project.

更新日期：2013-08-01 00:00:00

abstract：:We investigated early postnatal changes of the mesenteric circulation and its relationship to the systemic circulation in two groups of newborn infants. Group I (n = 10) was studied before the first feeding at 1 h and preprandially at 6 and 24 h. Group II (n = 10) was studied before the first feeding at 2 h of age and...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Linker DT,Vik T,Yao AC

更新日期：1994-09-01 00:00:00

abstract：INTRODUCTION:The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) serves 50% of infants and 25% of preschool-aged children in the United States and collects height and weight measurements from eligible children every 6 mo, making WIC data a valuable resource for studying childhood growth an...

journal_title：Pediatric research

authors： Crespi CM,Alfonso VH,Whaley SE,Wang MC

更新日期：2012-03-01 00:00:00

abstract：:Murine hybridoma antibodies directed against the capsule and O-side chain determinants of the Escherichia coli strain Bort (018ac:K1:H7) were evaluated for their ability to enhance bactericidal activity of cord blood against K1 E. coli strains possessing O antigens common in neonatal E. coli infection, i.e. 018, 07, a...

journal_title：Pediatric research

authors： Kim KS,Cross AS,Kaufmann B,Zollinger W,Sadoff J

更新日期：1990-12-01 00:00:00

abstract：:Sudden infant death syndrome is the most common cause of postneonatal infant mortality in the developed world. It is a diagnosis of exclusion with peak age of incidence between 2 and 6 mo. Fifty to 63% of these infants have a preexisting upper respiratory tract infection before death. We hypothesized that the immature...

journal_title：Pediatric research

authors： Blood-Siegfried J,Nyska A,Lieder H,Joe M,Vega L,Patterson R,Germolec D

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Kawasaki disease (KD) is an acute febrile illness associated with the development of vasculitis. Administration of intravenous immunoglobulin (IVIG) is the standard treatment for KD. However, IVIG treatment is not effective in approximately 15% of children with KD. Some reports have presented evidence of imm...

journal_title：Pediatric research

authors： Wakiguchi H,Hasegawa S,Suzuki Y,Kudo K,Ichiyama T

更新日期：2015-04-01 00:00:00

abstract：:Conversion of adenosine to inosine is decreased in adenosine deaminase (ADA)-deficient fibroblasts at all concentrations of adenosine tested. Adenosine is not differentially toxic to ADA-deficient fibroblasts except at very high (5 X 10(-4) -1 X 10(-3) M) adenosine levels. Conversion of [14C] adenosine to GTP is not d...

journal_title：Pediatric research

authors： Benke PJ,Dittmar D

更新日期：1976-07-01 00:00:00

abstract：:Antenatal cocaine administration is associated with increases in catecholamines and glucocorticoids and results in fetal hypoxemia, with the speculated potential for increased free radical formation in the fetus. Because of this, we hypothesized that antenatal cocaine exposure would produce not only accelerated pulmon...

journal_title：Pediatric research

authors： Sosenko IR

更新日期：1993-04-01 00:00:00

abstract：:To delineate the role of growth hormone (GH) in the development and function of the immune system, immunological parameters including quantitative immunoglobulins, T and B lymphocytes, phytohemagglutinin lymphoproliferative response and delayed hypersensitivity skin tests were studied in nine GH-deficient children pri...

journal_title：Pediatric research

authors： Abbassi V,Bellanti JA

更新日期：1985-03-01 00:00:00

abstract：:The objective of the present study is to compare the emergence of a circadian respiratory pattern in subsequent siblings of SIDS and controls infants to see whether the unique time and age of SIDS is correlated with altered circadian manifestations. During the first three months of life, a pattern in respiratory rates...

journal_title：Pediatric research

authors： Hoppenbrouwers T,Jensen DK,Hodgman JE,Harper RM,Sterman MB

更新日期：1980-04-01 00:00:00

abstract：:Various assay methods for detection of thyroid hormones in human milk were evaluated in recovery and dilution experiments after which the concentrations of thyroxine (T4) and 3,5,3'-triiodothyronine (T3) were measured and compared with those in serum. The effect of breast feeding on pituitary thyroid function of norma...

journal_title：Pediatric research

authors： Mizuta H,Amino N,Ichihara K,Harada T,Nose O,Tanizawa O,Miyai K

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Congenital portosystemic shunt (CPSS) has the potential to cause hepatic encephalopathy and thus needs long-term follow-up, but an effective follow-up method has not yet been established. We aimed to evaluate the importance of per-rectal portal scintigraphy (PRPS) for long-term follow-up of CPSS. METHODS:We...

journal_title：Pediatric research

authors： Cho Y,Tokuhara D,Shimono T,Yamamoto A,Higashiyama S,Kotani K,Kawabe J,Okano Y,Shiomi S,Shintaku H

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Serum caffeine concentrations >20 μg/ml (100 μmol/l) in infants treated for apnea of prematurity increases TNF-α and decreases IL-10, changes that perhaps are linked to comorbidities. We hypothesize that this proinflammatory cytokine profile may be linked to differential binding of caffeine to adenosine rece...

journal_title：Pediatric research

authors： Chavez-Valdez R,Ahlawat R,Wills-Karp M,Gauda EB

更新日期：2016-07-01 00:00:00

abstract：:Cardiac malformations (pulmonary trunk stenosis, ventricular septal defect, and double outlet right ventricle) were induced by the administration of two doses of retinoic acid (RA) to Wistar rats on d 13 of pregnancy. Contractile performance of the isolated perfused rat heart and its inotropic response to Ca2+ (0.6-10...

journal_title：Pediatric research

authors： Ostádalová I,Pexieder T,Ostádal B,Kolár F

更新日期：1995-12-01 00:00:00

abstract：:A 2-month-old white girl had severe liver disease (but without signs of hepatic necrosis, infection or cirrhosis), urinary cytomegalovirus, transient reduction of alpha 1-antitrypsin concentration and transient abnormal alpha 1-antitrypsin phenotype that were not present in her parents. Five serum specimens that were ...

journal_title：Pediatric research

authors： Hug G,Chuck G,Bowles B

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Newborn pigs offer theoretical advantages for studying newborn hypoxic-ischemic (HI) brain damage because of a development and structure similar to the human brain. However, the correlation between functional features and actual HI brain damage has not been reported. METHODS:Newborn pigs were examined daily...

journal_title：Pediatric research

authors： Barata L,Cabañas A,Lafuente H,Vargas C,Ceprián M,Campa L,Jiménez-Sánchez L,Pazos MR,Alvarez FJ,Martínez-Orgado J

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with a new supraglottic delivery system for surfactant atomization in an experimental neonatal model. ME...

journal_title：Pediatric research

authors： Nord A,Linner R,Milesi I,Zannin E,di Castri M,Bianco F,Dellacá RL,Cunha-Goncalves D,Perez-de-Sa V

更新日期：2020-05-01 00:00:00

abstract：:Carbon monoxide (CO) and the excitatory amino acid glutamate both dilate cerebral arterioles in newborn pigs. The key enzyme in CO synthesis is heme oxygenase, which is highly expressed in neurons with glutamatergic receptor activity as well as cerebral microvessels. During seizures the extracellular level of glutamat...

journal_title：Pediatric research

authors： Pourcyrous M,Bada HS,Parfenova H,Daley ML,Korones SB,Leffler CW

更新日期：2002-05-01 00:00:00