Influence of antenatal glucocorticoid on preterm lamb diaphragm.

abstract：:Pulmonary surfactant proteins SP-B and SP-C were isolated from lavage fluids of bovine lungs and recombined (lipid/proteins, 9/1, wt/wt) with dipalmitoyl phosphatidylcholine for testing in vitro and in surfactant-deficient adult rats. Using a pulsating bubble surfactometer, we found that inflation pressures of bubbles...

journal_title：Pediatric research

authors： Smith GB,Taeusch HW,Phelps DS,Keough KM

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Regular physical activity provides children with health and developmental benefits. This study investigated if active play and walking with the family dog was associated with better social-emotional development in young children. METHODS:We surveyed 1646 parents to ascertain if families with pre-schoolers o...

journal_title：Pediatric research

authors： Wenden EJ,Lester L,Zubrick SR,Ng M,Christian HE

更新日期：2020-07-06 00:00:00

abstract：:Galactose metabolism was studied in human ovarian tissue obtained from 14 women controls between 21 and 72 y of age, and one 21-y-old galactosemic patient with hypergonadotrophic hypogonadism. Tissue slices were incubated with 1-14C-galactose, and labeled intermediates were analyzed by anion-exchange column chromatogr...

journal_title：Pediatric research

authors： Xu YK,Ng WG,Kaufman FR,Lobo RA,Donnell GN

更新日期：1989-02-01 00:00:00

abstract：:Matrix metalloproteinases (MMP) are likely effectors of normal lung development, especially branching morphogenesis, angiogenesis, and extracellular matrix degradation. Because hyperoxia exposure (>95% O(2)) from d 4 to 14 in newborn rat pups leads to arrest of alveolarization and mimics newborn chronic lung disease, ...

journal_title：Pediatric research

authors： Hosford GE,Fang X,Olson DM

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), Staphylococcus aureus (SA), and Escherichia coli (EC) by preterm infant leukocytes are inconsistent. METHODS:...

journal_title：Pediatric research

authors： Prosser A,Hibbert J,Strunk T,Kok CH,Simmer K,Richmond P,Burgner D,Currie A

更新日期：2013-11-01 00:00:00

abstract：:The isobutyryl-CoA dehydrogenase (IBD) enzyme is involved in the degradation of valine. IBD deficiency was first reported in 1998 and subsequent genetic investigations identified acyl-CoA dehydrogenase (ACAD) 8, now IBD, as the gene responsible for IBD deficiency. Only three individuals homozygous or compound heterozy...

journal_title：Pediatric research

authors： Pedersen CB,Bischoff C,Christensen E,Simonsen H,Lund AM,Young SP,Koeberl DD,Millington DS,Roe CR,Roe DS,Wanders RJ,Ruiter JP,Keppen LD,Stein Q,Knudsen I,Gregersen N,Andresen BS

更新日期：2006-09-01 00:00:00

abstract：:Increased deposition of hyaluronan (HA) is part of the early response to fibrogenic stimulus in the lung exposed to bleomycin injury and has been associated with increased lung water in adult animals. Early respiratory distress syndrome (RDS) in premature infants is characterized by increased lung water, and late sequ...

journal_title：Pediatric research

authors： Juul SE,Kinsella MG,Jackson JC,Truog WE,Standaert TA,Hodson WA

更新日期：1994-02-01 00:00:00

abstract：:Carlo Agostoni, MD, and Kwang Sik Kim, MD, are the Guest Editors for this annual review issue on Nutrition and the Microbiome. Dr Agostoni is a Professor of Pediatrics at the Department of Clinical Sciences and Community Health, University of Milan, within the Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, ...

journal_title：Pediatric research

authors： Agostoni C,Kim KS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Irisin is a myokine secreted by skeletal muscle during physical activity. Irisin treatment increased cortical bone mineral density (BMD) in young healthy mice and restored bone and muscle mass loss in a mouse model of disuse-induced osteoporosis and muscular atrophy. In humans, Irisin was positively correlat...

journal_title：Pediatric research

authors： Colaianni G,Faienza MF,Sanesi L,Brunetti G,Pignataro P,Lippo L,Bortolotti S,Storlino G,Piacente L,D'Amato G,Colucci S,Grano M

更新日期：2019-03-01 00:00:00

abstract：:In a review of 13 documented cases of fetal alcohol syndrome (FAS), an increased incidence of life-threatening bacterial infections as well as a propensity to minor infections was observed. Five of 13 patients had had at least one episode of pneumonia, two had meningitis, and one had sepsis. A comprehensive immunologi...

journal_title：Pediatric research

authors： Johnson S,Knight R,Marmer DJ,Steele RW

更新日期：1981-06-01 00:00:00

abstract：:Several lines of evidence suggest that formula with protein content of 3.0 g/100 kcal does not fully meet the protein needs of very-low-birth weight infants. Our purpose was to compare nitrogen balance, metabolic status and growth in infants fed a standard (3.0 g/100 kcal; RegPro) and high (3.6 g/100 kcal; HiPro) prot...

journal_title：Pediatric research

authors： Cooke R,Embleton N,Rigo J,Carrie A,Haschke F,Ziegler E

更新日期：2006-02-01 00:00:00

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：:We measured body composition, basal metabolic rate (BMR), and total energy expenditure in 28 nonobese and 35 obese adolescents aged 12-18 y using indirect calorimetry and the doubly labeled water method. BMR was highly correlated with fat-free mass in both the nonobese and obese groups (r = 0.77 and 0.84, respectively...

journal_title：Pediatric research

authors： Bandini LG,Schoeller DA,Dietz WH

更新日期：1990-02-01 00:00:00

abstract：:Studies were conducted to assess the efficacy and safety of a synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome (RDS) in preterm (approximately 80% of normal gestation) infant rhesus monkeys. Surfactant was prepared consisting of the phospholipids dipalmitoylphosphatidyl choline...

journal_title：Pediatric research

authors： Revak SD,Merritt TA,Cochrane CG,Heldt GP,Alberts MS,Anderson DW,Kheiter A

更新日期：1996-04-01 00:00:00

abstract：:Normal hemostasis depends in part on the balance achieved between proaggregatory and prothrombotic platelet thromboxane A2, measured as its stable end-product thromboxane B2 (TXB2), and vascular prostacyclin (PGI2), which inhibits platelet aggregation and is antithrombotic. Cystathionine-beta-synthase deficiency is ch...

journal_title：Pediatric research

authors： Graeber JE,Slott JH,Ulane RE,Schulman JD,Stuart MJ

更新日期：1982-06-01 00:00:00

abstract：:Cerebral blood flow (CBF) measurement by near infrared spectroscopy (NIRS) using oxyhemoglobin (HbO2) as a tracer (CBF-HbO2) needs rapid changes in arterial oxygen saturation (SaO2) which often cannot be achieved in many sick infants. An alternative method based on the same adaptation of the Fick principle using i.v. ...

journal_title：Pediatric research

authors： Patel J,Marks K,Roberts I,Azzopardi D,Edwards AD

更新日期：1998-01-01 00:00:00

abstract：:L-selectin, a surface adhesion glycoprotein expressed on leukocytes, has a well-established role in mediating inflammation and lymphocyte recirculation. Recent evidence suggests that L-selectin may also influence hematopoiesis. We observed that a greater proportion of CD34+ cells express L-selectin in cord blood compa...

journal_title：Pediatric research

authors： Koenig JM,Baron S,Luo D,Benson NA,Deisseroth AB

更新日期：1999-06-01 00:00:00

abstract：:Hypoxia and other adverse conditions are commonly encountered by rapidly growing cells. The RNA-binding protein RBM3 (RNA-binding motif protein 3), which is transcriptionally induced by low temperature and hypoxia, has recently been implicated in survival of colon cancer cells by mechanisms involving cyclooxygenase-2 ...

journal_title：Pediatric research

authors： Wellmann S,Truss M,Bruder E,Tornillo L,Zelmer A,Seeger K,Bührer C

更新日期：2010-01-01 00:00:00

abstract：:In spontaneously breathing newborn lambs, alveolar hypoxia increases lung microvascular pressure, which causes lung lymph flow to increase and the concentration of protein in lymph to decrease. To see if this response derives from hypoxia itself rather than from the change in breathing pattern that occurs during hypox...

journal_title：Pediatric research

authors： Hansen TN,Haberkern CM,Hazinski TA,Bland RD

更新日期：1984-05-01 00:00:00

abstract：:The objective was to investigate any possible relationship between functional and structural vascular changes in women with low gestational age and/or low birth weight by analyzing the retinal vascular pattern in women with thoroughly documented blood pressure. Retinal vessel morphology was evaluated by digital image ...

journal_title：Pediatric research

authors： Kistner A,Jacobson L,Jacobson SH,Svensson E,Hellstrom A

更新日期：2002-06-01 00:00:00

abstract：:In this study, we have investigated the possible role of the pro-aggregatory arachidonic acid (AA) metabolite thromboxane, in the impaired function of neonatal platelets. In platelet-rich plasma thromboxane production (measured by radioimmunoassay of thromboxane B2) was not different between neonates and adults when s...

journal_title：Pediatric research

authors： Stuart MJ,Dusse J,Clark DA,Walenga RW

更新日期：1984-09-01 00:00:00

abstract：:The association between lung injury and thrombocytopenia was investigated by comparing the megakaryocyte and platelet counts, and platelet activation using P-selectin as a marker, between the prepulmonary (right atrial) and postpulmonary (left atrial) blood in adult and neonatal (preterm and term) rats with and withou...

journal_title：Pediatric research

authors： Yang J,Yang M,Xu F,Li K,Lee SK,Ng PC,Tam JS,Yuen PM,Fok TF

更新日期：2003-09-01 00:00:00

abstract：:Small bowel resection decreases brush border membrane (BBM) glucose uptake kinetics. Oral epidermal growth factor (EGF) returns net glucose transport across intact tissue to control levels despite persistence of a defect in BBM glucose uptake. The purpose of this study was to examine the effects of resection and EGF t...

journal_title：Pediatric research

authors： Chung BM,Wallace LE,Winkfein RK,O'Loughlin EV,Hardin JA,Gall DG

更新日期：2004-01-01 00:00:00

abstract：:The auditory brainstem response (ABR) was monitored in nine infant rhesus monkeys during the intravenous infusion of 50-168 mg/kg of unconjugated bilirubin. Sulfisoxazole (200 mg/kg) was sometimes given near the end of or just before the bilirubin infusion if no obvious ABR change had yet occurred. Five of the animals...

journal_title：Pediatric research

authors： Ahlfors CE,Bennett SH,Shoemaker CT,Ellis WG,Davis SL,Wennberg RP,Goetzman BW

更新日期：1986-06-01 00:00:00

abstract：:Fetal and maternal plasma noradrenaline responses to invasive procedures were determined in pregnancies of 18 to 37 wk gestation. Fetal umbilical venous blood sampling was performed either from the placental cord insertion, which is not innervated, or the intrahepatic vein, which is innervated, and thus may be more st...

journal_title：Pediatric research

authors： Giannakoulopoulos X,Teixeira J,Fisk N,Glover V

更新日期：1999-04-01 00:00:00

abstract：:Prenatal maternal stress has been shown to impair functioning in nonhuman primate offspring. Little is known about the effects of prenatal stress on intellectual and language development in humans because it is difficult to identify sufficiently large samples of pregnant women who have been exposed to an independent s...

journal_title：Pediatric research

authors： Laplante DP,Barr RG,Brunet A,Galbaud du Fort G,Meaney ML,Saucier JF,Zelazo PR,King S

更新日期：2004-09-01 00:00:00

abstract：:Opsonisation of heat-killed bakers yeast and C3 and C4 concentrations were determined in sera from 69 children with liver disease and 39 controls as simple screening procedures for abnormalities in the complement system. Where significant defects in these moieties were encountered, the activity of the following was me...

journal_title：Pediatric research

authors： Larcher VF,Wyke RJ,Vergani D,Mowat AP,Williams R

更新日期：1983-04-01 00:00:00

abstract：:The aim of this study was to evaluate the changes in Doppler transmitral flow patterns during the 1st d of life. Doppler echocardiography of the ascending aorta and mitral valve was performed serially in 20 normal neonates at 2, 12, and 24 h of age. A computer-interfaced digitizer pad was used to measure the following...

journal_title：Pediatric research

authors： Harada K,Shiota T,Takahashi Y,Tamura M,Toyono M,Takada G

更新日期：1994-04-01 00:00:00

abstract：:Meconium aspiration syndrome is a serious condition of the newborn characterized by pulmonary inflammation with substantial neutrophil infiltration. We recently showed that meconium is a potent activator of complement. The aim of the present study was to investigate a possible role for complement in meconium-induced n...

journal_title：Pediatric research

authors： Castellheim A,Pharo A,Fung M,Saugstad OD,Mollnes TE

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Intrauterine inflammation adversely affects cardiopulmonary, systemic, and cerebral hemodynamics in preterm neonates, but its impact on responses to endotracheal tube (ETT) suction, known to affect hemodynamics, is unknown. We hypothesized that intrauterine inflammation would alter the cardiopulmonary and ce...

journal_title：Pediatric research

authors： Galinsky R,Moss TJ,Polglase GR,Hooper SB

更新日期：2013-07-01 00:00:00