Abstract：
:What the study of EAE has taught us that has relevance to human demyelinating diseases is discussed.
journal_name
Neurol Clinjournal_title
Neurologic clinicsauthors
Arnason BGsubject
Has Abstractpub_date
1983-08-01 00:00:00pages
765-82issue
3eissn
0733-8619issn
1557-9875journal_volume
1pub_type
杂志文章abstract：:In a recent trial limited to arteriovenous malformations discovered not to have bled, medical management was superior to medical management plus intervention. The trial was halted after 226 randomizations and a mean follow-up of 3.3 years owing to a disparity favoring the medical arm. Eligible patients were selected a...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2014.12.006
更新日期：2015-05-01 00:00:00
abstract：:Electronystagmography in 1990 should identify a vestibular abnormality with which to associate the clinical symptoms. The vestibular test battery method and interpretation reveals its application in neurotologic diagnosis. ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-05-01 00:00:00
abstract：:Mortality and morbidity from kidney disease and the spectrum of renal-associated neurologic disease have changed markedly since the introduction of renal dialysis and with the advent of renal transplantation. This article includes historical studies of the neurologic complications of acute uremia, now fairly uncommon,...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(03)00052-5
更新日期：2002-02-01 00:00:00
abstract：:Progressive muscular atrophy (PMA) is a rare, sporadic, adult-onset motor neuron disease, clinically characterized by isolated lower motor neuron features; however, clinically evident upper motor neuron signs may emerge in some patients. Subclinical upper motor neuron involvement is identified pathologically, radiolog...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2015.07.005
更新日期：2015-11-01 00:00:00
abstract：:The anatomic and physiologic changes that occur during pregnancy are unique. A neurologist needs to be aware of normal pregnancy-induced physiologic changes in the cardiovascular, renal, hematologic, and autoimmune systems, and the local anatomic changes, which include alteration of body habitus and pelvic ligaments. ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2016.04.009
更新日期：2016-08-01 00:00:00
abstract：:Motor and phonic tics represent the clinic hallmark of Tourette syndrome. Since there is no diagnostic test for tics, the clinical recognition of phenomenology is essential for proper diagnosis. Some, and possibly most, motor tics are preceded by a premonitory urge or sensation that is relieved by the execution of the...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(05)70311-x
更新日期：1997-05-01 00:00:00
abstract：:Many substances, organic and manufactured, may induce peripheral nerve damage when exposed to them. The expected clinical phenotype is of a distal, sensory or sensorimotor polyneuropathy, often painful, with axonal characteristics on electrodiagnostic and histopathologic analysis. Treatment is limited; often, the only...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2004.12.003
更新日期：2005-05-01 00:00:00
abstract：:The etiology of pyogenic infections of the brain and meninges varies principally by age, predisposing causes or conditions, and anatomic site of the infection. An appreciation of these factors, plus the prudent use of noninvasive anatomic diagnostic techniques (such as CT) and examination of the CSF, will provide a ba...
journal_title：Neurologic clinics
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：:The evaluation and treatment of spinal cord injury continues to evolve, enhanced by new imaging modalities. Their application in reference to the cervical, thoracic, and lumbar spine is discussed. Treatment options, both conservative and surgical, are outlined. ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-08-01 00:00:00
abstract：:Traumatic injury to the posterior fossa is a complex pathologic condition because of the great heterogeneity of lesions present. Treatment of primary brain injuries and prevention of secondary brain injuries is the mainstay of management. It is imperative to recognize traumatic lesions of the posterior fossa early bec...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2014.07.010
更新日期：2014-11-01 00:00:00
abstract：:Rapidly progressive dementias (RPDs) are neurologic conditions that develop subacutely over weeks to months or, rarely, acutely over days. In contrast to most dementing conditions that take years to progress to death, RPD quickly can be fatal. It is critical to evaluate patients who have RPD without delay, usually in ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2007.04.001
更新日期：2007-08-01 00:00:00
abstract：:In vitro and in vivo studies of striatal dopamine receptor changes have been reviewed in this article. A background of receptor pharmacology methods has been included to assist the reader in assessing the merits of the published studies. Overall the literature is not consistent in the relevant observations in parkinso...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:The authors review iatrogenic complications of stereotactic surgery, including tumor biopsy, cyst or abscess aspiration, movement disorder surgery, and radiosurgery. The expected morbidities and steps taken to reduce complications are also discussed. ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(05)70366-2
更新日期：1998-02-01 00:00:00
abstract：:The author discusses the noninvasive tests and their roles relative to intravenous digital subtraction angiography in the assessment of patients with carotid disease. ...
journal_title：Neurologic clinics
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:Neoplastic meningitis appears to be increasing in frequency with improvements in the treatment of many cancers. It is most often recognized in patients with leukemia, breast cancer, lymphomas, and small-cell cancer of the lung, although it may be seen with virtually any malignancy. Treatment should include intrathecal...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-11-01 00:00:00
abstract：:This article describes the physiologic and neural mechanisms that cause neuromuscular fatigue in racquet sports: table tennis, tennis, squash, and badminton. In these intermittent and dual activities, performance may be limited as a match progresses because of a reduced central activation, linked to changes in neurotr...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2007.11.011
更新日期：2008-02-01 00:00:00
abstract：:Oxidative phosphorylation (OXPHOS) accounts for approximately 95% of the adenosine triphosphate (ATP) produced by the cell. The central nervous system, peripheral nervous system, cardiac muscle, skeletal muscle, and smooth muscle are highly susceptible to dysfunction of this complex enzyme system. Although most OXPHOS...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(05)70180-8
更新日期：2000-02-01 00:00:00
abstract：:Oromandibular disorders are functional disorders and associated pains in the anatomic region of the temporomandibular joint. Their diagnosis and treatment are controversial because of the lack of conformity concerning these disorders among health care providers. This article provides a clear classification of these di...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-11-01 00:00:00
abstract：:The three states of mammalian being--wakefulness, REM sleep, and NREM sleep--are not mutually exclusive and may occur simultaneously, oscillate rapidly, or appear in dissociated or incomplete form to produce primary sleep parasomnias. Dysfunctions of a wide variety of organ systems may take advantage of the sleeping s...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(05)70280-2
更新日期：1996-11-01 00:00:00
abstract：:MS has certain salient morphologic features that distinguish it from other disorders of white matter and that may represent points of departure for investigation. ...
journal_title：Neurologic clinics
pub_type： 杂志文章
doi：
更新日期：1983-08-01 00:00:00
abstract：:As I have indicated in the foregoing discussion, there are several syndromes that with various degrees of proof seem to be caused by unilateral vascular compression of a cranial nerve at the brain stem. Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'. As a conseq...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1985-05-01 00:00:00
abstract：:The term thoracic outlet syndromes, is a group designation for several distinct disorders (one of questionable validity) involving various components of the brachial plexus, the blood vessels, or both, at various points between the base of the neck and the axilla. Four of the five subgroups (true neurologic TOS, arter...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8619(05)70149-3
更新日期：1999-08-01 00:00:00
abstract：:The appropriate diagnosis of the patient with epilepsy is first dependent on a determination of the type of seizure. When the type of seizure has been determined, consideration must be given to the nature of the epileptic syndrome, including concerns regarding the etiology of the attacks. The gradual evolution of the ...
journal_title：Neurologic clinics
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:Brain metastases are a common complication of cancer and alter patient management more than metastases at any other site of distant progression. Supportive therapies include steroids and antiseizure medications. Definitive treatments include radiation therapy, surgery, and chemotherapy. The optimal choice of treatment...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2007.07.011
更新日期：2007-11-01 00:00:00
abstract：:Considerable evidence exists of hypothalamic dysfunction in patients with anorexia nervosa and bulimia nervosa. This dysfunction is reflected in disturbances of endocrine function including abnormalities of gonadotropin, growth hormone, and corticotropin-releasing hormone secretion. Whereas these disturbances are gene...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1988-02-01 00:00:00
abstract：:Given the magnitude of the problem of motor fluctuations in patients who have Parkinson's disease treated with levodopa, a significant effort has been expended by physicians, researchers, and pharmaceutical manufacturers over the years to find effective treatments. This article briefly reviews the medical options for ...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2008.05.006
更新日期：2008-08-01 00:00:00
abstract：:Most CNS fungal infections can be divided into those that occur in normal hosts and those that occur in the immunosuppressed host. Cryptococcal infection, however, is common in both groups. The usual clinical presentation of a CNS fungal infection is chronic headache and mental status change. The CSF shows a lymphocyt...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1986-02-01 00:00:00
abstract：:Botulinum toxin therapy has emerged as a treatment modality for a variety of spastic- or contracture-related muscle diseases. Its safety has been proven for long-term use in the treatment of benign essential blepharospasm, hemifacial spasm, and certain types of strabismus. Recent approval from the Federal Drug Adminis...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-02-01 00:00:00
abstract：:Most patients who have endured a stroke sustain behavioral changes, although in many instances these effects can be subtle. Although behavioral changes after a stroke tend to improve, they may persist and have serious effects on daily living activities. This article reviews the more familiar behavioral changes that fo...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2015.08.009
更新日期：2016-02-01 00:00:00
abstract：:"Deep brain stimulation is a safe and effective therapy for the management of a variety of neurologic conditions with Food and Drug Administration or humanitarian exception approval for Parkinson disease, dystonia, tremor, and obsessive-compulsive disorder. Advances in neurophysiology, neuroimaging, and technology hav...
journal_title：Neurologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.ncl.2020.09.004
更新日期：2021-02-01 00:00:00
