Abstract:
:Rapidly progressive dementias (RPDs) are neurologic conditions that develop subacutely over weeks to months or, rarely, acutely over days. In contrast to most dementing conditions that take years to progress to death, RPD quickly can be fatal. It is critical to evaluate patients who have RPD without delay, usually in a hospital setting, as they may have a treatable condition. This review discusses a differential diagnostic approach to RPD, emphasizing neurodegenerative, toxic and metabolic, infectious, autoimmune, neoplastic, and other conditions to consider.
journal_name
Neurol Clinjournal_title
Neurologic clinicsauthors
Geschwind MD,Haman A,Miller BLdoi
10.1016/j.ncl.2007.04.001subject
Has Abstractpub_date
2007-08-01 00:00:00pages
783-807, viiissue
3eissn
0733-8619issn
1557-9875pii
S0733-8619(07)00057-6journal_volume
25pub_type
杂志文章,评审abstract::The appropriate diagnosis of the patient with epilepsy is first dependent on a determination of the type of seizure. When the type of seizure has been determined, consideration must be given to the nature of the epileptic syndrome, including concerns regarding the etiology of the attacks. The gradual evolution of the ...
journal_title:Neurologic clinics
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract::In summary, PET and SPECT are versatile imaging modalities capable of providing dynamic information regarding the metabolism and physiology of brain and brain tumor. PET and SPECT are useful adjuncts to MRI and CT scanning in the important clinical areas of presurgical estimations of tumor grade. In addition, PET can ...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-05-01 00:00:00
abstract::A specific genetic diagnosis can be reached for most children with muscular dystrophy. Advanced diagnostics, including genetic testing and analysis of nonmuscle tissues, such as skin and blood, often allow the diagnosis to be reached using minimally invasive procedures. These diagnostic advances accompany improved und...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(03)00065-3
更新日期:2003-11-01 00:00:00
abstract::The nature, prevalence, and course of cognitive and emotional disturbances in multiple sclerosis (MS) are described in this article. Mild to moderate cognitive impairment is common in MS and may be more incapacitating than physical symptoms for some patients. Although existing neurologic and neuroimaging procedures ca...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-02-01 00:00:00
abstract::Sports-related concussions (SRCs) are common among athletes in the United States. Most athletes who sustain an SRC recover within 7 to 10 days; however, many athletes who sustain the injury do not recover as expected and experience prolonged, persistent symptoms. In this document, the authors provide an overview of th...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2017.03.008
更新日期:2017-08-01 00:00:00
abstract::The inflammatory myopathies are a heterogeneous group of disorders with recent evidence demonstrating differences in clinical features, pathologic changes, pathogenesis, and response to therapy. The inflammatory myopathies generally produce predominantly proximal, symmetric muscle weakness and wasting. Additional crit...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-08-01 00:00:00
abstract::Guidelines and quality measures for epilepsy care have the potential to improve the quality of epilepsy care. Quality measures are increasingly used for pay-for-performance. This article describes different guidelines and quality measures that have been used to identify best practices, types of best practices for use ...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2015.11.006
更新日期:2016-05-01 00:00:00
abstract::Neuropathies due to nutritional problems can affect certain patient populations and have a varied presentation because of multiple coexistent nutritional deficiencies. Clinicians should consider nutritional neuropathies in patients presenting with neuropathies. Clinicians should be alert for signs and symptoms of neur...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2013.02.002
更新日期:2013-05-01 00:00:00
abstract::Cervicogenic headache is pain referred to the head from a source in the cervical spine or mediated by cervical nerves. Clinical features allow for no more than a diagnosis of probable cervicogenic headache. Definitive diagnosis requires evidence of a cervical source of pain. For most treatments, the evidence is limite...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2013.11.005
更新日期:2014-05-01 00:00:00
abstract::Progressive muscular atrophy (PMA) is a rare, sporadic, adult-onset motor neuron disease, clinically characterized by isolated lower motor neuron features; however, clinically evident upper motor neuron signs may emerge in some patients. Subclinical upper motor neuron involvement is identified pathologically, radiolog...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2015.07.005
更新日期:2015-11-01 00:00:00
abstract::Epilepsy affects over one percent of the population, including nearly one million women of childbearing potential. Women with epilepsy represent a particularly challenging group for neurologists and other health care professionals. Affected women are unaware of many of the unique issues they face, including the relati...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(05)70024-4
更新日期:2001-05-01 00:00:00
abstract::There is often a fine line between medical malpractice and maloccurrance. Physicians need to develop techniques and skills that enhance the patient-physician relationship based on honesty and informed consent. Documentation and proper maintenance of medical records is demanded by the current legal and health care syst...
journal_title:Neurologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8619(05)70376-5
更新日期:1998-02-01 00:00:00
abstract::MS has certain salient morphologic features that distinguish it from other disorders of white matter and that may represent points of departure for investigation. ...
journal_title:Neurologic clinics
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::The respiratory system and the central nervous system are interconnected in a delicate balance; disorders in this equilibrium can have devastating consequences. Respiratory dysfunction, whether acute or chronic, may cause neurologic disease, including headache, encephalopathy, and in extreme cases, coma and death. Thi...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(03)00062-8
更新日期:2002-02-01 00:00:00
abstract::Nerve agents cause a rapidly fatal cholinergic crisis, but rapid, appropriate antidotal treatment saves lives. Survivors of nerve-agent poisoning generally are healthy, unlike survivors of some other chemical agent attacks. Neurologists can assist first responders and mass casualty planners materially by serving as re...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2004.12.013
更新日期:2005-05-01 00:00:00
abstract::Psychogenic movement disorders (PMDs) can present with varied phenomenology that may resemble organic movement disorders. The diagnosis is based on clinical evaluation with a supporting history and classic features on neurologic examination. Ancillary testing, such as imaging and neurophysiologic studies, can provide ...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2014.09.013
更新日期:2015-02-01 00:00:00
abstract::A large body of medical and ethical opinion holds that it is justifiable to terminate medical treatment for permanently unconscious persons. But opponents of particular decisions to withhold or withdraw treatment may argue that the decisions violate laws against homicide, pose a threat to the lives of other less sever...
journal_title:Neurologic clinics
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::There are a number of medications that effectively relieve symptoms in patients with functionally disabling tics. Neuroleptic drugs remain the most predictably effective tic-suppressing agents, but other approaches may be beneficial. This article reviews the spectrum of available therapies to suppress tics and provide...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(05)70321-2
更新日期:1997-05-01 00:00:00
abstract::Paraproteinemia frequently is associated with peripheral neuropathy. The clinical manifestations can be protean owing to the potential for multiple organ involvement. A methodical diagnostic approach to patients who have a plasma cell dyscrasia and neuropathy is necessary to ensure the appropriate detection of more wi...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2006.12.002
更新日期:2007-02-01 00:00:00
abstract::Classifications and definitions are essential to facilitate communication; promote accurate diagnostic criteria; develop, test, and use effective therapies; and specify knowledge gaps. This article describes the development of the International Classification of Vestibular Disorders (ICVD) initiative. It describes its...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2015.04.010
更新日期:2015-08-01 00:00:00
abstract::Recognizing and treating the cause of pain in the patient with cancer should be the initial approach to the management of this common symptom. Careful analysis of patients with cancer and pain has led to the elucidation of common neurologic pain syndromes unique to this disease process. Pain in patients with cancer is...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-05-01 00:00:00
abstract::This article reviews the evidence for comorbidity of migraine with psychiatric disorders, particularly the affective and anxiety disorders. Studies of the association between migraine and depression in both clinical and community studies have provided consistent evidence regarding a substantial degree of comorbidity b...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(05)70298-x
更新日期:1997-02-01 00:00:00
abstract::Oxidative phosphorylation (OXPHOS) accounts for approximately 95% of the adenosine triphosphate (ATP) produced by the cell. The central nervous system, peripheral nervous system, cardiac muscle, skeletal muscle, and smooth muscle are highly susceptible to dysfunction of this complex enzyme system. Although most OXPHOS...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(05)70180-8
更新日期:2000-02-01 00:00:00
abstract::Myasthenia gravis (MG) is an antibody-mediated muscle disease in which any skeletal muscle can be affected. MG may produce numerous symptoms and signs. To doctors and patients, it may seem like lung disease, stroke, heart disease, or the effects of emotional stress. This article explores the "territory" between MG and...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-05-01 00:00:00
abstract::Motor fluctuations and dyskinesias are common motor complications that manifest within the first few years from the initiation of therapy in patients with Parkinson disease. These complications negatively affect the quality of life and represent an important source of disability. A growing number of therapeutic option...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2010.03.014
更新日期:2010-11-01 00:00:00
abstract::Pseudotumor cerebri is a perplexing syndrome of increased intra-cranial pressure without a space-occupying lesion. The terminology for the disorder has changed over the years and the diagnostic criteria revised to reflect advances in diagnostic technology and insights into the disease process. The classification and n...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/S0733-8619(03)00096-3
更新日期:2004-02-01 00:00:00
abstract::Although intravenous thrombolysis with recombinant tissue plasminogen activator is a proven effective therapy for acute ischemic stroke, it is often insufficient to achieve recanalization in patients with large intracranial artery occlusions. In these cases, intra-arterial reperfusion techniques may be useful. Intra-a...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2013.03.009
更新日期:2013-08-01 00:00:00
abstract::The oldest-old represent the fastest growing segment of society, and the risk of developing dementia continues to increase with advancing age into the 9th and 10th decades of life. The most common form of dementia in the oldest-old is Alzheimer disease (AD), although there are often mixed pathologies contributing to d...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.ncl.2017.01.006
更新日期:2017-05-01 00:00:00
abstract::In patients with TIA or ischemic stroke of noncardiac origin antiplatelet drugs are able to decrease the risk of stroke by 11-15%, and the risk of stroke, MI, and vascular death by 15-22%, but not mortality. Low doses of aspirin (50-325 mg) are as effective as high doses and cause less gastrointestinal side effects. S...
journal_title:Neurologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8619(05)70196-1
更新日期:2000-05-01 00:00:00
abstract::In this series of clinical vignettes, the authors have attempted to provide a "feel" for the varied causes of syncope. The neurologist should be able to diagnose most causes of syncope using a simple algorithmic approach. Initial evaluation includes detailed clinical history, physical examination, and 12-lead ECG. Fol...
journal_title:Neurologic clinics
pub_type: 杂志文章
doi:10.1016/j.ncl.2006.02.002
更新日期:2006-05-01 00:00:00