XbaI, PstI, and BglII restriction enzyme maps of the two orientations of the varicella-zoster virus genome.

abstract：:By marker rescue with cloned herpes simplex virus 2 DNA fragments, we have mapped the temperature-sensitive mutations of a series of herpes simplex virus 2 mutants to a region of the herpes simplex virus 2 genome that lies within or near the coding sequences for the major DNA-binding protein, ICP8. In cells infected w...

journal_title：Journal of virology

authors： Spang AE,Godowski PJ,Knipe DM

更新日期：1983-01-01 00:00:00

abstract：:Viral infectivity factor (Vif) is one of the human immunodeficiency virus (HIV) accessory proteins and is conserved in the primate lentivirus group. This protein is essential for viral replication in vivo and for productive infection of nonpermissive cells, such as peripheral blood mononuclear cells (PBMC). Vif counte...

journal_title：Journal of virology

authors： Ribeiro AC,Maia e Silva A,Santa-Marta M,Pombo A,Moniz-Pereira J,Goncalves J,Barahona I

更新日期：2005-01-01 00:00:00

abstract：:The viral dynamics in human immunodeficiency virus type 1 (HIV-1) infection have been studied extensively using mathematical modeling, but data from other primate lentivirus systems are scarce. This study was initiated to increase the understanding of the differences and similarities between the different primate lent...

journal_title：Journal of virology

authors： Brandin E,Thorstensson R,Bonhoeffer S,Albert J

更新日期：2006-10-01 00:00:00

abstract：:Analysis of six monoclonal antibody-resistant (mar) mutants in herpes simplex virus type 1 glycoprotein B identified two type-common (II and III) and two type-specific (I and IV) antigenic sites on this molecule. To derive additional information on the location of these sites, mar mutations were mapped and nucleotide ...

journal_title：Journal of virology

authors： Highlander SL,Dorney DJ,Gage PJ,Holland TC,Cai W,Person S,Levine M,Glorioso JC

更新日期：1989-02-01 00:00:00

abstract：:When Epstein-Barr virus (EBV) negative cells (Raji) were treated with iododeoxyuridine, only the early antigen (EA) component was induced. There was no significant increase in EBV DNA and no virus particles were observed. Somatic-cell hybrids were prepared from the fusion of Raji and D98 cells (D98/Raji). When these c...

journal_title：Journal of virology

authors： Glaser R,Nonoyama M

更新日期：1974-07-01 00:00:00

abstract：:Herpesvirus nucleocapsids are translocated from their assembly site in the nucleus to the cytosol by acquisition of a primary envelope at the inner nuclear membrane which subsequently fuses with the outer nuclear membrane. This transport through the nuclear envelope requires homologs of the conserved herpesviral pUL31...

journal_title：Journal of virology

authors： Grimm KS,Klupp BG,Granzow H,Müller FM,Fuchs W,Mettenleiter TC

更新日期：2012-06-01 00:00:00

abstract：UNLABELLED:Understanding the entry and trafficking mechanism(s) of recombinant adeno-associated virus (rAAV) into host cells can lead to evolution in capsid and vector design and delivery methods, resulting in enhanced transduction and therapeutic gene expression. Variability of findings regarding the early entry pathw...

journal_title：Journal of virology

authors： Weinberg MS,Nicolson S,Bhatt AP,McLendon M,Li C,Samulski RJ

更新日期：2014-11-01 00:00:00

abstract：:Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that causes neurological diseases in a variety of warm-blooded animal species. There is general consensus that BDV can also infect humans, being a possible zoonosis. Although the clinical consequences of human BDV infection are still controversial,...

journal_title：Journal of virology

authors： Bajramovic JJ,Syan S,Brahic M,de la Torre JC,Gonzalez-Dunia D

更新日期：2002-06-01 00:00:00

abstract：:Upon immunization and restimulation with tumors induced by the endogenous AKR/Gross murine leukemia virus (MuLV), C57BL/6 mice generate vigorous H-2K(b)-restricted cytotoxic T-lymphocyte (CTL) responses to a determinant (KSPWFTTL) derived from the p15E transmembrane portion of the viral envelope glycoprotein. By contr...

journal_title：Journal of virology

authors： Kim V,Yewdell JW,Green WR

更新日期：2000-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) replicates through an error-prone process that may support the evolution of genetic variants resistant to the host cell antiviral response and interferon (IFN)-based therapy. We evaluated HCV-IFN interactions within a long-term culture system of Huh7 cell lines harboring different variants of a...

journal_title：Journal of virology

authors： Sumpter R Jr,Wang C,Foy E,Loo YM,Gale M Jr

更新日期：2004-11-01 00:00:00

abstract：:Several viruses, including members of the gammaherpesvirus family, encode proteins that are secreted into the extracellular environment. We have identified an abundant 44-kDa secreted protein that is present in the supernatant of fibroblasts infected with murine gammaherpesvirus 68 (gammaHV68; also referred to as MHV-...

journal_title：Journal of virology

authors： van Berkel V,Preiter K,Virgin HW 4th,Speck SH

更新日期：1999-05-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infections in sub-Saharan Africa represent about 56% of global infections. Study of active-site mutations (the V82A single mutation and the V82F I84V double mutation) in the less-studied South African HIV type 1 subtype C (C-SA) protease indicated that neither mutation had a signific...

journal_title：Journal of virology

authors： Mosebi S,Morris L,Dirr HW,Sayed Y

更新日期：2008-11-01 00:00:00

abstract：:Herpesviruses are important pathogens of humans and other animals. Herpesvirus infectious clones that can reconstitute phenotypically wild-type (wt) virus are extremely valuable tools for elucidating the roles of specific genes in virus pathophysiology as well as for making vaccines. Ictalurid herpesvirus 1 (channel c...

journal_title：Journal of virology

authors： Kunec D,Hanson LA,van Haren S,Nieuwenhuizen IF,Burgess SC

更新日期：2008-04-01 00:00:00

abstract：:Recombinant protein subunit AIDS vaccines have been based predominantly on the virus envelope protein. Such vaccines elicit neutralizing antibody responses that can provide type-specific sterilizing immunity, but in most cases do not confer protection against divergent viruses. In this report we demonstrate that a mul...

journal_title：Journal of virology

authors： Voss G,Manson K,Montefiori D,Watkins DI,Heeney J,Wyand M,Cohen J,Bruck C

更新日期：2003-01-01 00:00:00

abstract：:Cytotoxic T lymphocytes (CTL) play an important role in recovery from a number of viral infections. They are also implicated in virus-induced immunopathology as best demonstrated in lymphocytic choriomeningitis virus (LCMV) infection of adult immunocompetent mice. In the present study, the structure of the T-cell rece...

journal_title：Journal of virology

authors： Yanagi Y,Maekawa R,Cook T,Kanagawa O,Oldstone MB

更新日期：1990-12-01 00:00:00

abstract：:The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) host cell passages. High and low multiplicities were used to examine the effect of de...

journal_title：Journal of virology

authors： Weaver SC,Brault AC,Kang W,Holland JJ

更新日期：1999-05-01 00:00:00

abstract：:The enzymatic activity of recombinant influenza virus RNA polymerase is strictly dependent on the addition of a template RNA containing 5' and 3' viral sequences. Here we report the analysis of the binding specificity and physical characterization of the complex by using gel shift, modification interference, and densi...

journal_title：Journal of virology

authors： Tiley LS,Hagen M,Matthews JT,Krystal M

更新日期：1994-08-01 00:00:00

abstract：:We previously reported that the adenovirus type 5 E3 14.5-kilodalton protein (14.5K) forms a complex with E3 10.4K and that both proteins are required to down-regulate the epidermal growth factor receptor in adenovirus-infected human cells. Both proteins are also required to prevent cytolysis by tumor necrosis factor ...

journal_title：Journal of virology

authors： Krajcsi P,Tollefson AE,Anderson CW,Wold WS

更新日期：1992-03-01 00:00:00

abstract：:HIV-1 circulates within an infected host as a genetically heterogeneous viral population. Viral intrahost diversity is shaped by substitutional evolution and recombination. Although many studies have speculated that recombination could have a significant impact on viral phenotype, this has never been definitively demo...

journal_title：Journal of virology

authors： Brown RJ,Peters PJ,Caron C,Gonzalez-Perez MP,Stones L,Ankghuambom C,Pondei K,McClure CP,Alemnji G,Taylor S,Sharp PM,Clapham PR,Ball JK

更新日期：2011-06-01 00:00:00

abstract：:The enhancer within the long terminal repeats (LTRs) of acquired somatic mouse mammary tumor viruses (MMTV) can activate juxtaposed genes and induce mammary tumors. In contrast, germ line proviral MMTV genomes are integrated in the host genome and considered to be genetically confined transcription units. Here we demo...

journal_title：Journal of virology

authors： Stegalkina SS,Guerrero A,Walton KD,Liu X,Robinson GW,Hennighausen L

更新日期：1999-10-01 00:00:00

abstract：:Vaccinia virus replication is inhibited by etoposide and mitoxantrone even though poxviruses do not encode the type II topoisomerases that are the specific targets of these drugs. Furthermore, one can isolate drug-resistant virus carrying mutations in the viral DNA ligase and yet the ligase is not known to exhibit sen...

journal_title：Journal of virology

authors： Lin YC,Li J,Irwin CR,Jenkins H,DeLange L,Evans DH

更新日期：2008-06-01 00:00:00

abstract：:The DA strain of Theiler's virus, a murine picornavirus, causes a persistent infection of glial cells of the white matter of the spinal cord, associated with chronic inflammation and primary demyelination. The GDVII strain causes an acute fatal grey matter encephalomyelitis. We characterized the target cells of GDVII ...

journal_title：Journal of virology

authors： Aubert C,Brahic M

更新日期：1995-05-01 00:00:00

abstract：:The prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a formidable battle horse for the study of viral immunology, as well as viral persistence and associated diseases. Investigations with LCMV have uncovered basic mechanisms by which viruses avoid elimination by the host adaptive immune response. In ...

journal_title：Journal of virology

authors： Martínez-Sobrido L,Zúñiga EI,Rosario D,García-Sastre A,de la Torre JC

更新日期：2006-09-01 00:00:00

abstract：:To model human immunodeficiency virus (HIV) perinatal transmission, we studied infection of simian-human immunodeficiency virus (SHIV) SF162P3 in 10 pregnant Macaca nemestrina females and their offspring. Four of nine infants born to and suckled by these dams had evidence of infection, a transmission rate of 44.4% (95...

journal_title：Journal of virology

authors： Jayaraman P,Zhu T,Misher L,Mohan D,Kuller L,Polacino P,Richardson BA,Bielefeldt-Ohmann H,Anderson D,Hu SL,Haigwood NL

更新日期：2007-01-01 00:00:00

abstract：:Novel molecular approaches to inhibit human immunodeficiency virus type 1 (HIV-1) infection have received increasing attention because of the lack of effective antiviral drug therapies in vivo. We now demonstrate that cells can be intracellularly immunized by cytoplasmic expression of single-chain variable antibody fr...

journal_title：Journal of virology

authors： Shaheen F,Duan L,Zhu M,Bagasra O,Pomerantz RJ

更新日期：1996-06-01 00:00:00

abstract：:Productively infected bovine fibropapillomas were examined for bovine papillomavirus type 1 (BPV-1) E7 localization. BPV-1 E7 was observed in the cytoplasm of basal and lower spinous epithelial cells, coexpressed in the cytoplasm of basal cells with the E5 oncoprotein. E7 was also observed in nucleoli throughout the b...

journal_title：Journal of virology

authors： Bohl J,Hull B,Vande Pol SB

更新日期：2001-01-01 00:00:00

abstract：:Tobacco necrosis virus, strain D (TNV-D), is a positive-strand RNA virus in the genus Betanecrovirus and family Tombusviridae The production of its RNA-dependent RNA polymerase, p82, is achieved by translational readthrough. This process is stimulated by an RNA structure that is positioned immediately downstream of th...

journal_title：Journal of virology

authors： Newburn LR,White KA

更新日期：2017-03-29 00:00:00

abstract：:Gene mapping experiments show that Fis-1, a preferred integration region for Friend murine leukemia virus in hematopoietic neoplasms, is extremely closely linked to Int-2, a preferred integration region for mouse mammary tumor virus in mammary carcinomas. Studies at the RNA and DNA level prove that these loci are dist...

journal_title：Journal of virology

authors： Silver J,Buckler CE

更新日期：1986-12-01 00:00:00

abstract：:After isolation, the DNA of simian virus 40 appeared as a negative supertwist (form I) or as an open circle with at least one single-strand scission (form II). Under the denaturation conditions usually applied, such as heating in the presence of formaldehyde or application of alkali, form I molecules could appear as "...

journal_title：Journal of virology

authors： Mayer F,Mazaitis AJ,Pühler A

更新日期：1975-03-01 00:00:00

abstract：:The replication of many positive-strand RNA viruses [(+)RNA viruses] depends on the cellular protein GBF1, but its role in the replication process is not clear. In uninfected cells, GBF1 activates small GTPases of the Arf family and coordinates multiple steps of membrane metabolism, including functioning of the cellul...

journal_title：Journal of virology

authors： Viktorova EG,Gabaglio S,Meissner JM,Lee E,Moghimi S,Sztul E,Belov GA

更新日期：2019-10-15 00:00:00