Cooperative transformation and coexpression of bovine papillomavirus type 1 E5 and E7 proteins.

abstract：:Dengue virus (DENV) is a mosquito-borne flavivirus responsible for dengue disease, a major human health concern for which no specific therapies are available. Like other viruses, DENV relies heavily on the host cellular machinery for productive infection. In this study, we performed a genome-wide CRISPR-Cas9 screen us...

journal_title：Journal of virology

authors： Labeau A,Simon-Loriere E,Hafirassou ML,Bonnet-Madin L,Tessier S,Zamborlini A,Dupré T,Seta N,Schwartz O,Chaix ML,Delaugerre C,Amara A,Meertens L

更新日期：2020-03-17 00:00:00

abstract：:Many viruses express inhibitors of programmed cell death (apoptosis), thereby countering host defenses that would otherwise rapidly clear infected cells. To counter this, viruses such as adenoviruses and herpesviruses express recognizable homologs of the mammalian prosurvival protein Bcl-2. In contrast, the majority o...

journal_title：Journal of virology

authors： Okamoto T,Campbell S,Mehta N,Thibault J,Colman PM,Barry M,Huang DC,Kvansakul M

更新日期：2012-11-01 00:00:00

abstract：:We previously reported that human cytomegalovirus (HCMV) infection induces endoplasmic reticulum (ER) stress, resulting in activation of the unfolded protein response (UPR). Although some normal consequences of UPR activation (e.g., translation attenuation) are detrimental to viral infection, we have previously shown ...

journal_title：Journal of virology

authors： Isler JA,Maguire TG,Alwine JC

更新日期：2005-12-01 00:00:00

abstract：UNLABELLED:Viral myocarditis, which is most prevalently caused by coxsackievirus B3 (CVB3), is a serious clinical condition characterized by excessive myocardial inflammation. Recent studies suggest that regulation of protein acetylation levels by inhibiting histone deacetylase (HDAC) activity modulates inflammatory re...

journal_title：Journal of virology

authors： Zhou L,He X,Gao B,Xiong S

更新日期：2015-10-01 00:00:00

abstract：:Natural killer (NK) cells are components of the innate immunity and are key players in the defense against virus-infected and malignant cells. NK cells are particularly important in the innate defense against herpesviruses, including alphaherpesviruses. Aggravated and life-threatening alphaherpesvirus-induced disease ...

journal_title：Journal of virology

authors： De Pelsmaeker S,Dierick E,Klupp B,Mettenleiter TC,Cantoni C,Vitale M,Favoreel HW

更新日期：2019-03-21 00:00:00

abstract：:We have previously reported on the ubiquitylation and degradation of hepatitis C virus core protein. Here we demonstrate that proteasomal degradation of the core protein is mediated by two distinct mechanisms. One leads to polyubiquitylation, in which lysine residues in the N-terminal region are preferential ubiquityl...

journal_title：Journal of virology

authors： Suzuki R,Moriishi K,Fukuda K,Shirakura M,Ishii K,Shoji I,Wakita T,Miyamura T,Matsuura Y,Suzuki T

更新日期：2009-03-01 00:00:00

abstract：:Among the five serine incorporator (SERINC) family members, SERINC5 (Ser5) was reported to strongly inhibit HIV-1 replication, which is counteracted by Nef. Ser5 produces 5 alternatively spliced isoforms: Ser5-001 has 10 putative transmembrane domains, whereas Ser5-004, -005, -008a, and -008b do not have the last one....

journal_title：Journal of virology

authors： Zhang X,Zhou T,Yang J,Lin Y,Shi J,Zhang X,Frabutt DA,Zeng X,Li S,Venta PJ,Zheng YH

更新日期：2017-04-28 00:00:00

abstract：:Nonconservative substitutions for Tyr-115 in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) lead to enzymes displaying lower affinity for deoxynucleoside triphosphates (dNTPs) (A. M. Martín-Hernández, E. Domingo, and L. Menéndez-Arias, EMBO J. 15:4434-4442, 1996). Several mutations at th...

journal_title：Journal of virology

authors： Olivares I,Sánchez-Merino V,Martínez MA,Domingo E,López-Galíndez C,Menéndez-Arias L

更新日期：1999-08-01 00:00:00

abstract：:In adenovirus-infected cells, the epidermal growth factor receptor (EGF-R) is internalized from the cell surface via endosomes and is degraded, and the E3 10,400-dalton protein (10.4K protein) is required for this effect (C. R. Carlin, A. E. Tollefson, H. A. Brady, B. L. Hoffman, and W. S. M. Wold, Cell 57:135-144, 19...

journal_title：Journal of virology

authors： Tollefson AE,Stewart AR,Yei SP,Saha SK,Wold WS

更新日期：1991-06-01 00:00:00

abstract：:Five hepatoma cell lines, including CZHC/8571, PLC/PRF/5, Hep3B, HepG2, and HUH7, were inoculated with three diverse isolates of human immunodeficiency virus type 1 (HIV-1). Productive infection was noted in all hepatoma cell lines, and expression of viral p24 antigen lasted for over 3 months, but its level decreased ...

journal_title：Journal of virology

authors： Cao YZ,Friedman-Kien AE,Huang YX,Li XL,Mirabile M,Moudgil T,Zucker-Franklin D,Ho DD

更新日期：1990-06-01 00:00:00

abstract：:The unique region of the capsid protein VP1 (VP1u) of human parvovirus B19 (B19) elicits a dominant immune response and has a phospholipase A(2) (PLA(2)) activity, which is necessary for the infection. In contrast to the rest of the parvoviruses, the VP1u of B19 is thought to occupy an external position in the virion,...

journal_title：Journal of virology

authors： Ros C,Gerber M,Kempf C

更新日期：2006-12-01 00:00:00

abstract：:Varicella-zoster virus (VZV) encodes within its unique long region a gene product with protein kinase motifs. In a previous study, we demonstrated that immunoprecipitated VZV open reading frame (ORF) 47 protein was associated with a functional protein kinase activity, on the basis of its ability to both autophosphoryl...

journal_title：Journal of virology

authors： Ng TI,Keenan L,Kinchington PR,Grose C

更新日期：1994-03-01 00:00:00

abstract：:The NS5A nonstructural protein of hepatitis C virus (HCV) has been shown to inhibit the cellular interferon (IFN)-induced protein kinase R (PKR). PKR mediates the host IFN-induced antiviral response at least in part by inhibiting mRNA translation initiation through phosphorylation of the alpha subunit of eukaryotic in...

journal_title：Journal of virology

authors： He Y,Tan SL,Tareen SU,Vijaysri S,Langland JO,Jacobs BL,Katze MG

更新日期：2001-06-01 00:00:00

abstract：:Infection with human T-cell leukemia virus type 1 (HTLV-1) can result in the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic inflammatory disease of the central nervous system (CNS). HTLV-2 is highly related to HTLV-1 at the genetic level and shares a high degree of sequen...

journal_title：Journal of virology

authors： Banerjee P,Rochford R,Antel J,Canute G,Wrzesinski S,Sieburg M,Feuer G

更新日期：2007-02-01 00:00:00

abstract：:Plasmacytoid dendritic cells (pDC) poorly replicate human immunodeficiency virus type 1 (HIV-1) but efficiently transfer HIV-1 to adjacent CD4 T lymphocytes. We found that coculture with T lymphocytes downregulates SAMHD1 expression, enhances HIV-1 replication, and increases pDC maturation and alpha interferon (IFN-α)...

journal_title：Journal of virology

authors： Su B,Lederle A,Laumond G,Ducloy C,Schmidt S,Decoville T,Moog C

更新日期：2014-09-01 00:00:00

abstract：:Autographa californica nuclear polyhedrosis virus (AcMNPV) is a double-stranded DNA virus that expresses several immediate-early genes under the control of different promoters. The expression of one of these transcription units, IE-N, is shown here, by a transient expression assay, to be regulated by both cis- and tra...

journal_title：Journal of virology

authors： Carson DD,Summers MD,Guarino LA

更新日期：1991-02-01 00:00:00

abstract：:Replication of flock house virus (FHV) RNA1 and production of subgenomic RNA3 in the yeast Saccharomyces cerevisiae provide a useful tool for the dissection of FHV molecular biology and host-encoded functions involved in RNA replication. The replication template activity of RNA1 can be separated from its coding potent...

journal_title：Journal of virology

authors： Lindenbach BD,Sgro JY,Ahlquist P

更新日期：2002-04-01 00:00:00

abstract：:Retroviral recombination can occur between two viral RNA molecules (intermolecular) or between two sequences within the same RNA molecule (intramolecular). The rate of retroviral intramolecular recombination is high. Previous studies showed that, after a single round of replication, 50 to 60% of retroviral recombinati...

journal_title：Journal of virology

authors： Li T,Zhang J

更新日期：2002-10-01 00:00:00

abstract：:Upon cell entry, the genomes of herpes simplex virus type 1 (HSV-1) and adenovirus (Ad) associate with distinct nuclear structures termed ND10 or promyelocytic leukemia (PML) nuclear bodies (NBs). PML NB morphology is altered or disrupted by specific viral proteins as replication proceeds. We examined whether adeno-as...

journal_title：Journal of virology

authors： Fraefel C,Bittermann AG,Büeler H,Heid I,Bächi T,Ackermann M

更新日期：2004-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) productive replication in vitro is most often studied in fibroblasts. In vivo, fibroblasts amplify viral titers, but transmission and pathogenesis require the infection of other cell types, most notably epithelial cells. In vitro, the study of HCMV infection of epithelial cells has been al...

journal_title：Journal of virology

authors： Weng C,Lee D,Gelbmann CB,Van Sciver N,Nawandar DM,Kenney SC,Kalejta RF

更新日期：2018-07-31 00:00:00

abstract：:Hantaviruses are tripartite negative-sense RNA viruses and members of the Bunyaviridae family. The nucleocapsid (N) protein is encoded by the smallest of the three genome segments (S). N protein is the principal structural component of the viral capsid and is central to the hantavirus replication cycle. We examined in...

journal_title：Journal of virology

authors： Mir MA,Panganiban AT

更新日期：2004-08-01 00:00:00

abstract：:The early steps of the intracellular trafficking of human papillomavirus type 16 (HPV-16), -31, and -58 pseudovirions were studied by investigating the effects of drugs acting at defined points of endocytosis pathways on virus-like particle-mediated pseudoinfection by overexpression of a dominant-negative form of the ...

journal_title：Journal of virology

authors： Bousarghin L,Touzé A,Sizaret PY,Coursaget P

更新日期：2003-03-01 00:00:00

abstract：:To determine the extent and structure of genetic variation in dengue viruses (DENV) on a restricted spatial and temporal scale, we sequenced the E (envelope) genes of DENV-1, -2, and -3 isolates collected in 2001 from children enrolled in a prospective school-based study in Kamphaeng Phet, Thailand, and diagnosed with...

journal_title：Journal of virology

authors： Jarman RG,Holmes EC,Rodpradit P,Klungthong C,Gibbons RV,Nisalak A,Rothman AL,Libraty DH,Ennis FA,Mammen MP Jr,Endy TP

更新日期：2008-06-01 00:00:00

abstract：:The host cell receptor for Moloney murine leukemia virus was solubilized from murine L-cell membranes and characterized. In initial studies designed to identify a receptor-rich cell line, different mouse cells were screened for binding to Moloney gp70, the viral envelope glycoprotein which determines host cell-binding...

journal_title：Journal of virology

authors： Johnson PA,Rosner MR

更新日期：1986-06-01 00:00:00

abstract：:The zinc finger antiviral protein (ZAP) is a recently isolated host antiviral factor. It specifically inhibits the replication of Moloney murine leukemia virus (MLV) and Sindbis virus (SIN) by preventing the accumulation of viral RNA in the cytoplasm. For this report, we mapped the viral sequences that are sensitive t...

journal_title：Journal of virology

authors： Guo X,Carroll JW,Macdonald MR,Goff SP,Gao G

更新日期：2004-12-01 00:00:00

abstract：:A malignant glioma cell line was infected with the human T-lymphotropic virus type IIIB isolate of the human immunodeficiency virus. Infection appeared to be latent rather than productive. Through contact with monocytic or lymphoid cells, the virus present in the glioma cells could be transmitted and gave rise to a fu...

journal_title：Journal of virology

authors： Chiodi F,Fuerstenberg S,Gidlund M,Asjö B,Fenyö EM

更新日期：1987-04-01 00:00:00

abstract：:Intracellular mature vaccinia virions are wrapped by cisternae, derived from virus-modified trans-Golgi or endosomal membranes, and then transported via microtubules to the cell periphery. Two viral proteins, encoded by the F13L and B5R open reading frames, are essential for the membrane-wrapping step. Previous transf...

journal_title：Journal of virology

authors： Husain M,Moss B

更新日期：2002-08-01 00:00:00

abstract：:In vitro transcription of the avian tumor virus RNA by RNA-directed DNA polymerase is initiated on the unique cellular 4S RNA. Previous studies have shown that on the average there is one such RNA primer hydrogen bonded to each viral 35S RNA. The present study confirms that finding and demonstrates that, at least for ...

journal_title：Journal of virology

authors： Taylor JM,Illmensee R

更新日期：1975-09-01 00:00:00

abstract：:Infectious pancreatic necrosis virus of fish, infectious bursal disease virus of chickens, Tellina virus and oyster virus of bivalve molluscs, and drosophila X virus of Drosophila melanogaster are naked icosahedral viruses with an electron microscopic diameter of 58 to 60 nm. The genome of each of these viruses consis...

journal_title：Journal of virology

authors： Dobos P,Hill BJ,Hallett R,Kells DT,Becht H,Teninges D

更新日期：1979-11-01 00:00:00

abstract：:Vaccinia virus DNA fragments that have been denatured by alkali and then neutralized contain a fraction that rapidly reforms duplex structures. The fraction is enriched by fractionating on hydroxyapatite columns and serves as as substrate for digestion by two restriction endonucleases isolated from Hemophilus parainfl...

journal_title：Journal of virology

authors： DeFilippes F

更新日期：1975-01-01 00:00:00