Coronavirus multiplication: locations of genes for virion proteins on the avian infectious bronchitis virus genome.

abstract：:Understanding how HIV-1 persists during effective antiretroviral therapy (ART) should inform strategies to cure HIV-1 infection. We hypothesize that proliferation of HIV-1-infected cells contributes to persistence of HIV-1 infection during suppressive ART. This predicts that identical or monotypic HIV-1 DNA sequences ...

journal_title：Journal of virology

authors： Wagner TA,McKernan JL,Tobin NH,Tapia KA,Mullins JI,Frenkel LM

更新日期：2013-02-01 00:00:00

abstract：:Feline calicivirus is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of Caliciviridae. We have examined the entry process of feline calicivirus (FCV). An earlier study demonstrated that acidification in endosomes may be required. We have confirmed this observatio...

journal_title：Journal of virology

authors： Stuart AD,Brown TD

更新日期：2006-08-01 00:00:00

abstract：:The matrix (M1) protein of influenza virus is a major structural component, involved in regulation of viral ribonucleoprotein transport into and out of the nucleus. Early in infection, M1 is distributed in the nucleus, whereas later, it is localized predominantly in the cytoplasm. Using immunofluorescence microscopy a...

journal_title：Journal of virology

authors： Whittaker G,Kemler I,Helenius A

更新日期：1995-01-01 00:00:00

abstract：:Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved understanding of the regions within the DENV genome and its encoded proteins that are required for the virus replication cycle will expedite the development of urgentl...

journal_title：Journal of virology

authors： Eyre NS,Johnson SM,Eltahla AA,Aloi M,Aloia AL,McDevitt CA,Bull RA,Beard MR

更新日期：2017-11-14 00:00:00

abstract：:The existence of novel endogenous retrovirus elements in the chicken genome, designated EAV-HP, with close sequence identity to the env gene of avian leukosis virus (ALV) subgroup J has been reported (L. M. Smith, A. A. Toye, K. Howes, N. Bumstead, L. N. Payne, and K. Venugopal, J. Gen. Virol. 80:261-268, 1999). To re...

journal_title：Journal of virology

authors： Sacco MA,Flannery DM,Howes K,Venugopal K

更新日期：2000-02-01 00:00:00

abstract：:It was recently shown that the 7a protein of severe acute respiratory syndrome coronavirus induces biochemical changes associated with apoptosis. In this study, the mechanism by which the 7a protein induces apoptosis was examined. The 7a protein was tested for the ability to inhibit cellular gene expression because se...

journal_title：Journal of virology

authors： Kopecky-Bromberg SA,Martinez-Sobrido L,Palese P

更新日期：2006-01-01 00:00:00

abstract：:Adeno-associated virus type 2 (AAV2) preferentially integrates its genome into the AAVS1 locus on human chromosome 19. Preferential integration requires the AAV2 Rep68 or Rep78 protein (Rep68/78), a Rep68/78 binding site (RBS), and a nicking site within AAVS1 and may also require an RBS within the virus genome. To obt...

journal_title：Journal of virology

authors： McAlister VJ,Owens RA

更新日期：2007-09-01 00:00:00

abstract：:The Zaire ebolavirus (EBOV) glycoprotein (GP) is cleaved into two subunits (GP1 and GP2) that are both required for virus attachment and entry into cells. Sequence changes in the GP have been proposed to increase pathogenesis and to alter virus growth properties. Mutations in GP acquired during EBOV tissue culture pas...

journal_title：Journal of virology

authors： Ruedas JB,Arnold CE,Palacios G,Connor JH

更新日期：2018-09-12 00:00:00

abstract：:Tumor progression locus 2 (TPL2) is a serine/threonine kinase that belongs to the mitogen-activated protein 3 kinase (MAP3K) family, and it plays an important role in pathogen infection. The trimer complex of TPL2, p105, and ABIN2 is essential for maintenance of TPL2 steady-state levels and host cell response to patho...

journal_title：Journal of virology

authors： Zhang K,Yan M,Hao J,Shen C,Zhu Z,Zhang D,Hou J,Xu G,Li D,Zheng H,Liu X

更新日期：2020-12-23 00:00:00

abstract：:The host cell-specific factor 1 gene (hcf-1) of the baculovirus Autographa californica nuclear polyhedrosis virus (AcMNPV) is required for the efficient replication and/or stability of reporter plasmids carrying an AcMNPV-derived origin of DNA replication in a cell-specific manner; hcf-1 is required for reporter plasm...

journal_title：Journal of virology

authors： Lu A,Miller LK

更新日期：1996-08-01 00:00:00

abstract：:The organization of adeno-associated virus serotype 4 (AAV 4) DNA was probed by using restriction enzymes. The cleavage sites of the following enzymes were mapped: BglII, BamI, HincII, KpnI, PstI, SalI, SstI, and XhoI. The orientation of transcription on the physical cleavage map was determined by locating the fragmen...

journal_title：Journal of virology

authors： Muster CJ,Lee YS,Newbold JE,Leis J

更新日期：1980-09-01 00:00:00

abstract：:Murine norovirus (MNV), a prevalent pathogen of laboratory mice, shares many characteristics with human noroviruses. Previous results indicated that passage of MNV1 in the macrophage cell line RAW 264.7 results in attenuation in STAT1-deficient mice (C. E. Wobus, S. M. Karst, L. B. Thackray, K. O. Chang, S. V. Sosnovt...

journal_title：Journal of virology

authors： Bailey D,Thackray LB,Goodfellow IG

更新日期：2008-08-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in peripheral nerve ganglia. Periodically, the virus reactivates from this latent reservoir and is transported to the original site of infection. Strains of HSV-1 have been noted to vary greatly in their virulence and reactivation efficiencies in a...

journal_title：Journal of virology

authors： Grams TR,Edwards TG,Bloom DC

更新日期：2020-07-16 00:00:00

abstract：:Harvard Medical School convened a meeting of biomedical and clinical experts on 5 March 2015 on the topic of "Rethinking the Response to Emerging Microbes: Vaccines and Therapeutics in the Ebola Era," with the goals of discussing the lessons from the recent Ebola outbreak and using those lessons as a case study to aid...

journal_title：Journal of virology

authors： Knipe DM,Whelan SP

更新日期：2015-08-01 00:00:00

abstract：:The unique region of the capsid protein VP1 (VP1u) of human parvovirus B19 (B19) elicits a dominant immune response and has a phospholipase A(2) (PLA(2)) activity, which is necessary for the infection. In contrast to the rest of the parvoviruses, the VP1u of B19 is thought to occupy an external position in the virion,...

journal_title：Journal of virology

authors： Ros C,Gerber M,Kempf C

更新日期：2006-12-01 00:00:00

abstract：:Combined Southern blot hybridization analyses of DNA digests of several clinical strains of Streptococcus pneumoniae have revealed the presence of a gene (hblR), or part of it, similar to the hbl7 gene coding for the cell wall lytic enzyme of the temperate HB-746 phage. The results confirmed that the genome of HB-746,...

journal_title：Journal of virology

authors： Romero A,Lopez R,Garcia P

更新日期：1992-05-01 00:00:00

abstract：:Partial E1 envelope glycoprotein gene sequences and complete structural polyprotein sequences were used to compare divergence and construct phylogenetic trees for the genus Alphavirus. Tree topologies indicated that the mosquito-borne alphaviruses could have arisen in either the Old or the New World, with at least two...

journal_title：Journal of virology

authors： Powers AM,Brault AC,Shirako Y,Strauss EG,Kang W,Strauss JH,Weaver SC

更新日期：2001-11-01 00:00:00

abstract：:Characterizations of genetic variations among hepatitis delta virus (HDV) isolates have focused principally on phylogenetic analysis of sequences, which vary by 30 to 40% among three genotypes and about 10 to 15% among isolates of the same genotype. The significance of the sequence differences has been unclear but cou...

journal_title：Journal of virology

authors： Casey JL,Gerin JL

更新日期：1998-04-01 00:00:00

abstract：:Reverse genetic analyses of negative-strand RNA (NSR) viruses have provided enormous advances in our understanding of animal viruses over the past 20 years, but technical difficulties have hampered application to plant NSR viruses. To develop a reverse genetic approach for analysis of plant NSR viruses, we have engine...

journal_title：Journal of virology

authors： Ganesan U,Bragg JN,Deng M,Marr S,Lee MY,Qian S,Shi M,Kappel J,Peters C,Lee Y,Goodin MM,Dietzgen RG,Li Z,Jackson AO

更新日期：2013-10-01 00:00:00

abstract：:Type III interferons ([IFNs] IFN-lambda and interleukin-28 and -29 [IL-28/29]) are recently recognized cytokines with innate antiviral effects similar to those of type I IFNs (IFN-alpha/beta). Like IFN-alpha/beta, IFN-lambda-expression can be induced by viruses, and it is believed that type I and III IFNs are regulate...

journal_title：Journal of virology

authors： Stoltz M,Klingström J

更新日期：2010-09-01 00:00:00

abstract：UNLABELLED:Viruses that spread systemically from a peripheral site of infection cause morbidity and mortality in the human population. Innate myeloid cells, including monocytes, macrophages, monocyte-derived dendritic cells (mo-DC), and dendritic cells (DC), respond early during viral infection to control viral replica...

journal_title：Journal of virology

authors： Kaminsky LW,Sei JJ,Parekh NJ,Davies ML,Reider IE,Krouse TE,Norbury CC

更新日期：2015-10-01 00:00:00

abstract：:Marek's disease herpesvirus (MDV)-transformed lymphoblastoid tumor cell lines were characterized for the presence of the surface markers. Monoclonal antibodies were used for CD3 (T-cell receptor [TCR] complex), TCR1, TCR2, and TCR3, CD4, CD8, and Ia antigen by indirect fluorescence staining followed by microscopic exa...

journal_title：Journal of virology

authors： Schat KA,Chen CL,Calnek BW,Char D

更新日期：1991-03-01 00:00:00

abstract：:We have constructed a series of vectors based on simian foamy virus type 1 (SFV-1) to define the minimum cis-acting elements required for gene transfer. To characterize these vectors, we inserted the coding sequence of the bacterial lacZ gene linked to the cytomegalovirus immediate-early gene promoter. Introduction of...

journal_title：Journal of virology

authors： Wu M,Chari S,Yanchis T,Mergia A

更新日期：1998-04-01 00:00:00

abstract：:Murine leukemia viruses isolated from radiation-induced BALB/c leukemias were characterized with respect to viral proteins and RNA. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the viral structural proteins revealed that for p12, p15, p30, and gp70, three of four electrophoretic variants of...

journal_title：Journal of virology

authors： Ellis RW,Hopkins N,Fleissner E

更新日期：1980-02-01 00:00:00

abstract：:The complete nucleotide sequence of the NS mRNA of vesicular stomatitis virus (New Jersey serotype) was established from two cDNA clones spanning the entire coding region of the mRNA. The gene is 856 nucleotides long and can code for a polypeptide of 274 amino acids. Comparison with the nucleotide sequence of the NS g...

journal_title：Journal of virology

authors： Gill DS,Banerjee AK

更新日期：1985-07-01 00:00:00

abstract：:The papillomavirus (PV) E2 protein is a critical regulator of viral transcription and genome replication. We previously reported that tyrosine (Y) 138 of HPV-31 E2 is phosphorylated by the fibroblast growth factor receptor 3 (FGFR3) kinase. In this study, we generated quasiviruses containing G418-selectable HPV-31 gen...

journal_title：Journal of virology

authors： Jose L,Androphy EJ,DeSmet M

更新日期：2020-07-01 00:00:00

abstract：:The entire measles virus (MV) hemagglutinin (HA)-coding region was reconstructed from cloned cDNAs and used as part of a hybrid transcription unit to replace a region of the adenovirus type 5 genome corresponding to the entire E1a transcription unit and most of the E1b transcription unit. The resulting recombinant vir...

journal_title：Journal of virology

authors： Alkhatib G,Briedis DJ

更新日期：1988-08-01 00:00:00

abstract：:RNA silencing is a potent means of antiviral defense in plants and animals. A hallmark of this defense response is the production of 21- to 24-nucleotide viral small RNAs via mechanisms that remain to be fully understood. Many viruses encode suppressors of RNA silencing, and some viral RNAs function directly as silenc...

journal_title：Journal of virology

authors： Itaya A,Zhong X,Bundschuh R,Qi Y,Wang Y,Takeda R,Harris AR,Molina C,Nelson RS,Ding B

更新日期：2007-03-01 00:00:00

abstract：:Strategies were developed to insert the neo resistance marker into the junction between L DNA and the right terminal repetitive H DNA of herpesvirus saimiri. Recombinant viruses were selectable in permissive epithelioid cultures. The human T-cell line Jurkat could be infected persistently with the Neor virus; the cell...

journal_title：Journal of virology

authors： Grassmann R,Fleckenstein B

更新日期：1989-04-01 00:00:00

abstract：:The ICP18.5 gene (UL28) of herpes simplex virus type 1 is a member of a well-conserved gene family among herpesviruses and is thought to play a role in localization of viral glycoproteins. We have cloned, sequenced, and expressed the entire pseudorabies virus (PRV) ICP18.5 open reading frame in Escherichia coli as a C...

journal_title：Journal of virology

authors： Pederson NE,Enquist LW

更新日期：1991-07-01 00:00:00