Far-field somatosensory evoked potentials after stimulation of the tibial nerve.

abstract：OBJECTIVE:To identify regional metabolic brain networks related specifically to the presence of tremor in PD. BACKGROUND:The pathophysiology of parkinsonian tremor is unknown. Because tremor in PD occurs mainly in repose, we used resting state PET with 18F-fluorodeoxyglucose (FDG) to identify specific metabolic brain ...

journal_title：Neurology

authors： Antonini A,Moeller JR,Nakamura T,Spetsieris P,Dhawan V,Eidelberg D

更新日期：1998-09-01 00:00:00

abstract：:Article abstract Depressive disorders (DDs) are the most common type of psychiatric co-morbidity in patients with epilepsy. They are more likely to occur in patients with partial seizure disorders of temporal and frontal lobe origin and are more frequent among patients with poorly controlled seizures. Despite their re...

journal_title：Neurology

authors： Kanner AM,Balabanov A

更新日期：2002-04-23 00:00:00

abstract：:Neurologic disorders are among the most frequent causes of morbidity and mortality in the United States. Moreover, the current shortfall of neurologists is expected to worsen over the coming decade. As a consequence, many patients with neurologic disorders will be treated by physicians and primary care providers witho...

journal_title：Neurology

authors： Sandrone S,Berthaud JV,Chuquilin M,Cios J,Ghosh P,Gottlieb-Smith RJ,Kushlaf H,Mantri S,Masangkay N,Menkes DL,Nevel KS,Sarva H,Schneider LD

更新日期：2019-01-22 00:00:00

abstract：:Mammalian spinal neurons grown in tissue culture were used to study the effects of the four convulsants-penicillin, pentylenetetrazol, picrotoxin, and bicuculline-on these neurons' responses to amino acids. Bath application of all four convulsants produced paroxysmal depolarizing events in the neurons; iontophoresis o...

journal_title：Neurology

authors： Macdonald RL,Barker JL

更新日期：1978-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship of white matter hyperintensities (WMH) with decline in lower extremity function (LEF) over approximately 3 years in dementia-free older adults with memory complaints. METHODS:We obtained brain MRI data from 458 community-dwelling adults, aged 70 years or over, at baseline, and fr...

journal_title：Neurology

authors： Moon SY,de Souto Barreto P,Rolland Y,Chupin M,Bouyahia A,Fillon L,Mangin JF,Andrieu S,Cesari M,Vellas B,MAPT\/DSA Study Group.

更新日期：2018-04-10 00:00:00

abstract：OBJECTIVE:To investigate the prevalence, predictors, and clinical relevance of cortical superficial siderosis (cSS) progression in cerebral amyloid angiopathy (CAA). METHODS:Consecutive patients with symptomatic CAA meeting Boston criteria in a prospective cohort underwent baseline and follow-up MRI within 1 year. cSS...

journal_title：Neurology

authors： Pongpitakmetha T,Fotiadis P,Pasi M,Boulouis G,Xiong L,Warren AD,Schwab KM,Rosand J,Gurol ME,Greenberg SM,Viswanathan A,Charidimou A

更新日期：2020-04-28 00:00:00

abstract：:Pergolide, a long-acting central dopamine agonist, was used as monotherapy in 16 parkinsonian patients. A mean daily dose of 6.3 mg resulted in 73% improvement of parkinsonian disability. Clinical improvement after acute administration of one dose of pergolide was similar to that observed after levodopa plus a periphe...

journal_title：Neurology

authors： Mear JY,Barroche G,de Smet Y,Weber M,Lhermitte F,Agid Y

更新日期：1984-07-01 00:00:00

abstract：OBJECTIVE:To characterize the clinical course of pathologically diagnosed hippocampal sclerosis dementia (HSD). BACKGROUND:Dementia associated with HSD is incompletely characterized. Previous studies suggest similarities to both Alzheimer disease (AD) and frontotemporal dementia (FTD). METHODS:Case-control analysis o...

journal_title：Neurology

authors： Blass DM,Hatanpaa KJ,Brandt J,Rao V,Steinberg M,Troncoso JC,Rabins PV

更新日期：2004-08-10 00:00:00

abstract：:A 59-year-old woman with levodopa-responsive parkinsonism complicated by motor fluctuations and generalized levodopa dyskinesia underwent bilateral subthalamic deep brain stimulation (STN DBS) 7 years after symptom onset. DBS improved levodopa-responsive upper extremity bradykinesia but aggravated speech, swallowing, ...

journal_title：Neurology

authors： Tarsy D,Apetauerova D,Ryan P,Norregaard T

更新日期：2003-07-22 00:00:00

abstract：:We measured plasma norepinephrine levels in patients with familial amyloid polyneuropathy. Patients with orthostatic hypotension had low basal plasma norepinephrine levels, which did not increase after postural change. On the basis of biochemical findings that suggest depletion of peripheral norepinephrine, DL-threo-3...

journal_title：Neurology

authors： Suzuki T,Higa S,Sakoda S,Hayashi A,Yamamura Y,Takaba Y,Nakajima A

更新日期：1981-10-01 00:00:00

abstract：:Biochemical analysis of muscle in a 37-year-old man with exercise intolerance, myalgia, recurrent myoglobinuria, and retinitis pigmentosa showed phosphoglycerate kinase (PGK) deficiency. Kinetic and physical characteristics of the mutant enzyme differed from those of two previously reported cases, suggesting a distinc...

journal_title：Neurology

authors： Tonin P,Shanske S,Miranda AF,Brownell AK,Wyse JP,Tsujino S,DiMauro S

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:Clinical trials of fetal neural tissue transplantation for Huntington disease (HD) have been conducted with variable clinical results. However, no long-term analysis of graft survival and integration has been published. Here, we report the pathologic findings in two patients with HD who died 74 and 79 months ...

journal_title：Neurology

authors： Keene CD,Sonnen JA,Swanson PD,Kopyov O,Leverenz JB,Bird TD,Montine TJ

更新日期：2007-06-12 00:00:00

abstract：:We performed a case-control study to investigate the role of recent infection as stroke risk factor and to identify pathogenetic pathways linking infection and stroke. We examined 166 consecutive patients with acute cerebrovascular ischemia and 166 patients hospitalized for nonvascular and noninflammatory neurologic d...

journal_title：Neurology

authors： Grau AJ,Buggle F,Becher H,Zimmermann E,Spiel M,Fent T,Maiwald M,Werle E,Zorn M,Hengel H,Hacke W

更新日期：1998-01-01 00:00:00

abstract：:To determine whether the complete correction of hyperglycemia of diabetes can rapidly improve abnormal peripheral nerve function, eight hyperglycemic insulin-requiring diabetics underwent 3 days of glucose control with an artificial endocrine pancreas, the BIOSTATOR Glucose Controller. Comparison of neurologic assessm...

journal_title：Neurology

authors： Service FJ,Daube JR,O'Brien PC,Dyck PJ

更新日期：1981-11-01 00:00:00

abstract：:The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared with that of two overlapping controls, matched and general (n = 629), exposed to nonteratogenic agents. Our study suggests a twofold increase in the rate of ma...

journal_title：Neurology

authors： Diav-Citrin O,Shechtman S,Arnon J,Ornoy A

更新日期：2001-07-24 00:00:00

abstract：:Despite recent advances in the molecular genetics of Alzheimer's disease (AD), several fundamental questions concerning risk of illness are unresolved, namely, if Mendelian factors account for the incidence of the disease, and if AD is an inevitable consequence of the aging process. This study was designed to address ...

journal_title：Neurology

authors： Lautenschlager NT,Cupples LA,Rao VS,Auerbach SA,Becker R,Burke J,Chui H,Duara R,Foley EJ,Glatt SL,Green RC,Jones R,Karlinsky H,Kukull WA,Kurz A,Larson EB,Martelli K,Sadovnick AD,Volicer L,Waring SC,Growdon JH,Fa

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To determine the relative efficacy of amantadine, pemoline, and placebo in treatment of multiple sclerosis (MS)-related fatigue. BACKGROUND:Fatigue is a complication of MS. Both pemoline and amantadine have been used to treat MS fatigue, but their relative efficacy is not known. METHODS:Amantadine, pemoline...

journal_title：Neurology

authors： Krupp LB,Coyle PK,Doscher C,Miller A,Cross AH,Jandorf L,Halper J,Johnson B,Morgante L,Grimson R

更新日期：1995-11-01 00:00:00

abstract：:Lymphocyte subpopulations ("active' T cells, total T cells, and B cells), leukocyte migration, lymphocyte transformation, complements (CH50, C3, and C4), and immune complexes in serum and cerebrospinal fluid were studied in 23 patients with subacute sclerosing panencephalitis. The percentage of active T cells was norm...

journal_title：Neurology

authors： Derakhshan I,Massoud A,Foroozanfar N,Nikbin B,Lotfi J,Shakib N,Ala F

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVE:To establish a variant of sporadic prion disease as the sporadic form of fatal familial insomnia (FFI). BACKGROUND:FFI is a recently described prion disease characterized clinically by severe sleep impairment, dysautonomia, and motor signs, and pathologically by atrophy of thalamic nuclei, especially the med...

journal_title：Neurology

authors： Parchi P,Capellari S,Chin S,Schwarz HB,Schecter NP,Butts JD,Hudkins P,Burns DK,Powers JM,Gambetti P

更新日期：1999-06-10 00:00:00

abstract：:Sorivudine provides a unique nucleoside analog with significantly enhanced both in vitro and in vitro activity and enhanced oral bioavailability. Early indications from controlled studies indicate that sorivudine therapy is superior to acyclovir for the treatment of localized zoster in individuals with HIV infection a...

journal_title：Neurology

authors： Whitley RJ

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to survey our patients about their experience with our clinic's telemedicine program to better understand telemedicine's utility for families, and to improve patient satisfaction and ultimately patient care. METHODS:This was a prospective survey study of patients and the...

journal_title：Neurology

authors： Qubty W,Patniyot I,Gelfand A

更新日期：2018-05-08 00:00:00

abstract：:We studied three patients with Leigh's syndrome (LS) and cytochrome c oxidase (COX) deficiency. Biochemical studies in brain, muscle, heart, liver, kidney, and fibroblasts disclosed a generalized COX deficiency. Kinetic studies of COX activity in brain mitochondria showed a low Vmax and a normal Km for reduced cytochr...

journal_title：Neurology

authors： Lombes A,Nakase H,Tritschler HJ,Kadenbach B,Bonilla E,DeVivo DC,Schon EA,DiMauro S

更新日期：1991-04-01 00:00:00

abstract：:The initial decision in the management of idiopathic parkinsonism is whether any pharmacotherapy is indicated. There is no conclusive evidence that treatment is helpful before symptoms start to affect the patient's life, although some neurologists believe that deprenyl, also known as selegiline, could be useful. Once ...

journal_title：Neurology

authors： Calne DB

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To improve clinical recognition and provide research diagnostic criteria for three clinical syndromes associated with frontotemporal lobar degeneration. METHODS:Consensus criteria for the three prototypic syndromes-frontotemporal dementia, progressive nonfluent aphasia, and semantic dementia-were developed b...

journal_title：Neurology

authors： Neary D,Snowden JS,Gustafson L,Passant U,Stuss D,Black S,Freedman M,Kertesz A,Robert PH,Albert M,Boone K,Miller BL,Cummings J,Benson DF

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:To describe a large series of BIN1 patients, in which a novel founder mutation in the Roma population of southern Spain has been identified. METHODS:Patients diagnosed with centronuclear myopathy (CNM) at 5 major reference centers for neuromuscular disease in Spain (n = 53) were screened for BIN1 mutations. ...

journal_title：Neurology

authors： Cabrera-Serrano M,Mavillard F,Biancalana V,Rivas E,Morar B,Hernández-Laín A,Olive M,Muelas N,Khan E,Carvajal A,Quiroga P,Diaz-Manera J,Davis M,Ávila R,Domínguez C,Romero NB,Vílchez JJ,Comas D,Laing NG,Laporte J,Ka

更新日期：2018-07-24 00:00:00

abstract：:Recent genetic studies show that the apolipoprotein E epsilon 4 allele (ApoE-epsilon 4) is a risk factor for Alzheimer's disease (AD). If ApoE-epsilon 4 individuals develop AD as they get older, we would expect a decrease in ApoE-epsilon 4 allele frequency with increasing age. We found a marked decline in ApoE-epsilon...

journal_title：Neurology

authors： Rebeck GW,Perls TT,West HL,Sodhi P,Lipsitz LA,Hyman BT

更新日期：1994-08-01 00:00:00

abstract：:Large prospective epidemiologic studies have linked the consumption of coffee and other caffeinated beverages to a reduced risk of subsequently developing PD. Caffeine as well as more specific antagonists of the adenosine A(2A) receptor have also now been found to attenuate neurotoxicity in a mouse model of PD. The co...

journal_title：Neurology

authors： Schwarzschild MA,Chen JF,Ascherio A

更新日期：2002-04-23 00:00:00

abstract：:A 60-year-old woman suffered from recurrent episodes of fever, hypertension, facial flushing, vomiting, stridor, slowly progressive symptoms of hypohidrosis, and orthostatic hypotension. The episodes were synchronous with elevated catecholamine concentration in plasma and urine. This is an example of paroxysmal autono...

journal_title：Neurology

authors： Mitsui T,Kawai H,Taguchi E,Miyamoto H,Saito S

更新日期：1993-09-01 00:00:00

abstract：:Large doses of phenytoin were administered on 159 occasions to 139 adult patients. Most patients had had more than three seizures or were in status epilepticus. Based on response to treatment, patients could be divided into two groups. Those with excellent response (recurrent seizures, 10%; mortality, 1%) included kno...

journal_title：Neurology

authors： Cranford RE,Leppik IE,Patrick B,Anderson CB,Kostick B

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVES:To examine associations between 1H magnetic resonance spectroscopic imaging (1H MRSI)-detected hippocampal creatine to N-acetylaspartate (Cr/NAA) ratios and neuropsychological measures sensitive to mesial temporal lobe function. BACKGROUND:The measurement of 1H MRSI-detected hippocampal metabolites has prov...

journal_title：Neurology

authors： Martin RC,Sawrie S,Hugg J,Gilliam F,Faught E,Kuzniecky R

更新日期：1999-12-10 00:00:00