Abstract:
:Active locomotion of wireless capsule endoscopes has the potential to improve the diagnostic yield of this painless technique for the diagnosis of gastrointestinal tract disease. In order to design effective locomotion mechanisms, a quantitative measure of the propelling force required to effectively move a capsule inside the gastrointestinal tract is necessary. In this study, we introduce a novel wireless platform that is able to measure the force opposing capsule motion, without perturbing the physiologic conditions with physical connections to the outside of the gastrointestinal tract. The platform takes advantage of a wireless capsule that is magnetically coupled with an external permanent magnet. A secondary contribution of this manuscript is to present a real-time method to estimate the axial magnetic force acting on a wireless capsule manipulated by an external magnetic field. In addition to the intermagnetic force, the platform provides real-time measurements of the capsule position, velocity, and acceleration. The platform was assessed with benchtop trials within a workspace that extends 15 cm from each side of the external permanent magnet, showing average error in estimating the force and the position of less than 0.1 N and 10 mm, respectively. The platform was also able to estimate the dynamic behavior of a known resistant force with an error of 5.45%. Finally, an in vivo experiment on a porcine colon model validated the feasibility of measuring the resistant force in opposition to magnetic propulsion of a wireless capsule.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Natali CD,Beccani M,Obstein KL,Valdastri Pdoi
10.1088/0967-3334/35/7/1197subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1197-214issue
7eissn
0967-3334issn
1361-6579journal_volume
35pub_type
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journal_title:Physiological measurement
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journal_title:Physiological measurement
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journal_title:Physiological measurement
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journal_title:Physiological measurement
pub_type: 杂志文章
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journal_title:Physiological measurement
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doi:10.1088/1361-6579/aaee19
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journal_title:Physiological measurement
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journal_title:Physiological measurement
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journal_title:Physiological measurement
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journal_title:Physiological measurement
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