Abstract:
:Electrical impedance tomography (EIT) is a recent imaging technique based on electrical impedance, offering the possibility of measuring pulmonary perfusion. In the present study the influence of several pulmonary haemodynamical parameters on the EIT signal were investigated. First, the influence on the systolic wave of the EIT signal (delta Zsys) of stroke volume, large pulmonary artery distensibility (both assessed by means of MRI) and the extent of the pulmonary peripheral vascular bed in 11 emphysematous patients (reduced peripheral vascular bed) and 9 controls (normal peripheral vascular bed) was investigated. Second, the influence of hypoxic pulmonary vasoconstriction on delta Zsys was examined in 14 healthy subjects. Finally, the origin of the diastolic wave was examined in three patients with atrioventricular dissociation. Multiple regression analysis showed that delta Zsys was only dependent on the variable emphysema (p < 0.02), but not dependent on stroke volume (p < 0.3) or pulmonary artery distensibility (p > 0.9). The mean value of delta Zsys for emphysematous patients (131 +/- 32 arbitrary units (AU)) was significantly lower (p < 0.001) than in the control group (200 +/- 39). In the group of healthy subjects delta Zsys decreased significantly (p < 0.001) during hypoxia (193 +/- 38 AU) compared with rest measurements (260 +/- 62 AU). The absence of the diastolic wave in the cardiological patients suggests the influence of reverse venous blood flow on the EIT signal. It is concluded that volume changes in the small pulmonary vessels contribute significantly to the EIT signal. Moreover, the hypoxia induced decrease in delta Zsys indicates the potential of EIT for measuring pulmonary vascular responses to external stimuli.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Vonk Noordegraaf A,Kunst PW,Janse A,Marcus JT,Postmus PE,Faes TJ,de Vries PMdoi
10.1088/0967-3334/19/2/013subject
Has Abstractpub_date
1998-05-01 00:00:00pages
263-73issue
2eissn
0967-3334issn
1361-6579journal_volume
19pub_type
杂志文章abstract::Acupuncture (ACU) is known to be effective in ischemia treatment, and glutamate (GLU) excitotoxicity is an important factor in neuronal cell death. We observed the effect of ACU on cerebral blood flow (%CBF) and DeltaGLU (the changes in GLU release) in the ischemic stroke rat model of diabetic mellitus (DM). A global ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/5/003
更新日期:2010-05-01 00:00:00
abstract::The measurement of the complex respiratory impedance at a high temporal resolution is described. The measurement of impedance is correlated with the breathing cycle using electrical transthoracic impedance. This allows the determination of the complex impedance at any fixed point in the respiratory cycle, which result...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/3/019
更新日期:1993-08-01 00:00:00
abstract::Skinfold anthropometry is a widely practiced technique often with little appreciation of its limitations. The large residual error appearing in any regressions of body density versus sums of skinfolds is primarily due to biological causes, in particular the non-constancy of the ratio of subcutaneous to total body fat....
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/19/3/008
更新日期:1998-08-01 00:00:00
abstract::A new method to image and quantify intra-abdominal haemorrhage using electrical impedance tomography (EIT) was tested in vivo. Supine peritoneal dialysis patients were monitored using an 8-electrode hemiarray placed on the anterior abdomen. EIT measurements were recorded using the EPack II data acquisition system befo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/2/001
更新日期:2011-02-01 00:00:00
abstract::The widening application of automatic external defibrillators (AEDs) presents very strong requirements for external electrocardiogram (ECG) signal analysis. Highly accurate detection of shockable rhythms is required, aimed to approach the maximum of 100% sensitivity and specificity. In a previous study the performance...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/2/302
更新日期:2001-05-01 00:00:00
abstract::Neuromagnetic recordings were used to check if electrical stimulation of the auditory nerve in cochlear-implant patients activates cortical auditory areas in a similar manner as acoustic stimulation in normal hearing subjects or whether the excitation processes are different. The waveform of the evoked magnetic field ...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/0967-3334/14/4a/014
更新日期:1993-11-01 00:00:00
abstract::We aim to investigate whether phase shift between respiratory oscillations in cerebral blood flow velocity (CBFV) and arterial blood pressure (ABP) is associated with changes in cerebral autoregulation (CA) or reflects the mechano-elastic properties of the cerebrovascular bed. The relationships between respiratory pha...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/38/2/310
更新日期:2017-02-01 00:00:00
abstract::Electrical impedance tomography (EIT) could be used as a portable non-invasive means to image the development of ischaemic stroke or haemorrhage. The purpose of this study was to examine if this was possible using time difference imaging, in the anesthetised rat using 40 spring-loaded scalp electrodes with applied con...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/6/765
更新日期:2016-06-01 00:00:00
abstract::The back-projected independent components (BICs) of single-trial, auditory P300 and contingent negative variation (CNV) evoked potentials (EPs) were derived using independent component analysis (ICA) and cluster analysis. The method was tested in simulation including a study of the electric dipole equivalents of the s...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/8/001
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:In this paper, a support vector machine (SVM) approach using statistical features, P wave absence, spectrum features, and length-adaptive entropy are presented to classify ECG rhythms as four types: normal rhythm, atrial fibrillation (AF), other rhythm, and too noisy to classify. APPROACH:The proposed algori...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aac7aa
更新日期:2018-06-25 00:00:00
abstract::Peripheral vasculature disease is strongly correlated with cardiovascular-associated mortality. Monitoring circulation health, especially in the peripheral limbs, is vital to detecting clinically significant disease at a stage when it can still be addressed through medical intervention. Electrical impedance tomography...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/3/006
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of the detection of brief orofacial pain sensations from easily recordable physiological signals by means of machine learning techniques. APPROACH:A total of 47 subjects underwent periodontal probing and indicated each instance of pain perception by means of a push button. Simu...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aadf0c
更新日期:2018-09-27 00:00:00
abstract::The paper describes the development of an electrical impedance tomography (EIT) system for gynecologic research. The GIT (gynecological impedance tomography) system has 48 electrodes and is embedded on a small space (30 mm diameter and 20 mm height) inside of the vaginal probe. The system provides real-time (one shot ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/5/849
更新日期:2012-05-01 00:00:00
abstract::A major problem confronting application of impedance techniques to studies of disease is the extraction of intrinsic properties of the tissue from the measured impedances, which unavoidably involve geometric factors as well. Amongst the foremost are the sizes and locations of the measuring electrode arrays, and this p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/34/11/1513
更新日期:2013-11-01 00:00:00
abstract::The state-dependent portion of cardio-vagal baroreflex control is called baroreflex hyteresis: we observe hysteresis when RR interval and carotid diameter depend on both the direction and value of arterial pressure. The elasticity of arterial walls, as well as the responsiveness of central command reset controls the r...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/6/009
更新日期:2010-06-01 00:00:00
abstract::We present an adaptive algorithm for solving the inverse problem in electrical impedance tomography. To strike a balance between the accuracy of the reconstructed images and the computational efficiency of the forward and inverse solvers, we propose to combine an adaptive mesh refinement technique with the adaptive Ka...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/6/1111
更新日期:2014-06-01 00:00:00
abstract::A simple wearable device for sit-to-stand timing detection was designed and constructed with rate gyroscopes and accelerometers and a dedicated adaptive algorithm. The method was validated by comparison with optoelectronic equipment. Results from the comparison showed a maximal error always lower than 2.5 x 10(-2) s f...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/8/006
更新日期:2006-08-01 00:00:00
abstract::Accelerometer wear location may influence physical activity estimates. This study investigates this relationship through the examination of activity patterns throughout the day. Participants from the aging research evaluating accelerometry (AREA) study (n men = 37, n women = 47, mean age (SD) = 78.9 (5.5) years)...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/10/1852
更新日期:2016-10-01 00:00:00
abstract::Dual-energy x-ray absorptiometry (DXA) is a precise, widely used method for measuring bone mineral density (BMD), usually of the lumbar spine and femoral neck. Recent developments, such as a lower x-ray tube current and pixel by pixel analysis, enable smaller bones and thinner tissues volumes, as in the hand, to be me...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/18/3/008
更新日期:1997-08-01 00:00:00
abstract::Body surface potential maps recorded during catheter pace mapping can facilitate the localization of the site of origin of ventricular tachycardia. In this study, we investigated the value of a realistic computer model of the human ventricular myocardium in generating body surface potential maps as templates for ident...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/18/4/010
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The Actiwatch 2 (AW2) is a wrist-worn accelerometer typically used to measure sleep. Although it can measure physical activity, there is limited evidence supporting its validity. We assessed the validity and reliability of the AW2 to measure sedentary behavior and physical activity (light, moderate, vigorous ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aba80f
更新日期:2020-09-04 00:00:00
abstract::The outside of the skin of the forearm is typically 15 mV more negative than the inside. Stretching the skin causes a reduction in the magnitude of this skin potential V, which we observe as a motion artifact delta V. We seek to determine the origin of this motion artifact by successively stripping 12 layers of the sk...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/17/2/003
更新日期:1996-05-01 00:00:00
abstract::Fetal hiccups emerge as early as nine weeks post-conception, being the predominant diaphragmatic movement before 26 weeks of gestation. They are considered as a programmed isometric inspiratory muscle exercise of the fetus in preparation for the post-natal respiratory function, or a manifestation of a reflex circuitry...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/6/005
更新日期:2007-06-01 00:00:00
abstract::An accurate reproducible measurement of left ventricular volume is important in the evaluation of cardiac disease. Four methods of left ventricular volume measurement by radionuclide ventriculography have been compared and their reproducibility assessed in a patient group. The methods studied were a geometric method, ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/1/004
更新日期:1993-02-01 00:00:00
abstract::The aim of this study was to establish whether analysis of the left ventricular pressure waveform provides indicative information about cardiac load and contractility and to develop an algorithm for computer-based assessment of changes in these variables. In eight healthy standard breed anaesthetized open-chest pigs, ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/12/003
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of maternal hyperoxygenation on fetal heart rate (FHR) when applied for suspected fetal distress during the second stage of term labor. APPROACH:A single-center randomized controlled trial was conducted in a tertiary care hospital in The Netherlands. Participants were included durin...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abc0b6
更新日期:2020-12-11 00:00:00
abstract::The recently-introduced technique of detrended fluctuation analysis (DFA) for heart-rate variability appears to yield improved prognostic power in cardiovascular disease through calculation of the fractal scaling exponent alpha. However, the physiological meaning of alpha remains unclear. In DFA, the signal is segment...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/23/2/314
更新日期:2002-05-01 00:00:00
abstract::The objective of this study was to adapt a novel near-infrared diffuse correlation spectroscopy (DCS) flow-oximeter for simultaneous and continuous monitoring of relative changes in cerebral blood flow (rCBF) and cerebral oxygenation (i.e. oxygenated/deoxygenated/total hemoglobin concentration: Δ[HbO2]/Δ[Hb]/ΔTHC) dur...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/10/2135
更新日期:2014-10-01 00:00:00
abstract::Measurements of blood volume pulse (BVP) and skin conductance are commonly used as indications of psychological arousal in affective computing and human-machine interfaces. To date, palmar surfaces remain the primary site for these measurements. Placement of sensors on palmar surfaces, however, is undesirable when rec...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/32/10/002
更新日期:2011-10-01 00:00:00
abstract::A gamma fit facilitates smoothing and extrapolation of distorted tracer-dilution curves in blood flow studies. Theoretically based empirical estimators were developed as simple alternatives to direct regression approaches from simulated gamma distributions with a wide range of shape asymmetry. Key curve features of pe...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/4/401
更新日期:2001-11-01 00:00:00