Modelling the electrical properties of bladder tissue--quantifying impedance changes due to inflammation and oedema.


:Electrical impedance spectroscopy has been developed as a potential method for the diagnosis of carcinoma in epithelial tissues. An understanding of the influence of structural changes in the tissue on the properties measured using this technique is essential for interpreting measured data and optimization of probe design. In contrast to other tissue types, carcinoma in situ of the bladder gives rise to an increase in electrical impedance over the kHz-MHz frequency range in comparison to normal tissue. Finite element models of the urothelium and the underlying superficial lamina propria have been constructed and solved in order to ascertain the influence of structural changes associated with malignancy, oedema and inflammation on the measured electrical properties of the tissue. Sensitivity analysis of results from a composite tissue model suggests that the increase in lymphocyte density in the lamina propria associated with an inflammatory response to the infiltration of urine into the tissue may explain these unusual electrical properties.


Physiol Meas


Walker DC,Smallwood RH,Keshtar A,Wilkinson BA,Hamdy FC,Lee JA




Has Abstract


2005-06-01 00:00:00














  • Estimation of sleep stages in a healthy adult population from optical plethysmography and accelerometer signals.

    abstract:OBJECTIVE:This paper aims to report on the accuracy of estimating sleep stages using a wrist-worn device that measures movement using a 3D accelerometer and an optical pulse photoplethysmograph (PPG). APPROACH:Overnight recordings were obtained from 60 adult participants wearing these devices on their left and right w...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Beattie Z,Oyang Y,Statan A,Ghoreyshi A,Pantelopoulos A,Russell A,Heneghan C

    更新日期:2017-10-31 00:00:00

  • Home monitoring of within-breath respiratory mechanics by a simple and automatic forced oscillation technique device.

    abstract::Spirometry is the gold standard to determine the presence of airflow obstruction, but it requires volitional participation and needs qualified supervision. The forced oscillation technique (FOT) measures respiratory input impedance (Zrs) during spontaneous breathing and it could be useful for unsupervised monitoring o...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Dellacà RL,Gobbi A,Pastena M,Pedotti A,Celli B

    更新日期:2010-04-01 00:00:00

  • Effect of composition on the dielectric properties of hydrogels for biomedical applications.

    abstract::The effect of composition on the dielectric properties of hydrogels for biomedical applications is experimentally investigated. The hydrogels, containing hydroxyethylcellulose (HEC), are characterized by means of the impedance spectroscopy technique. The real and imaginary parts of the electrical impedance of the hydr...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Alexe-Ionescu AL,Barbero G,Freire FC,Merletti R

    更新日期:2010-10-01 00:00:00

  • Validation of x-ray fluorescence measurements of metals in toenail clippings against inductively coupled plasma mass spectrometry in a Nigerian population.

    abstract:OBJECTIVE:Metal exposures have been linked with many adverse health outcomes affecting nearly every system in the body. Exposure to metals has been tracked primarily using blood. Blood metal concentrations have drawbacks as biomarkers stemming from the metals' short biologic half-lives, shipping and storage requirement...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Specht AJ,Kponee K,Nkpaa KW,Balcom PH,Weuve J,Nie LH,Weisskopf MG

    更新日期:2018-08-31 00:00:00

  • Generalizability of extracellular-to-intracellular fluid ratio using bio-impedance spectroscopy.

    abstract::Generalizability theory was used to investigate the score consistency of observed extracellular fluid/intracellular fluid (ECF/ICF) ratio measurements for both the global and leg-segmental bio-impedance spectroscopy methods. The test instrument used was a Xitron Hydra ECF/ICF Bio-Impedance Analyzer System, model 4200 ...

    journal_title:Physiological measurement

    pub_type: 杂志文章,随机对照试验


    authors: Turner AA,Lozano-Nieto A,Bouffard M

    更新日期:2006-04-01 00:00:00

  • A comparison of methods for estimating left ventricular volumes from radionuclide ventriculography.

    abstract::An accurate reproducible measurement of left ventricular volume is important in the evaluation of cardiac disease. Four methods of left ventricular volume measurement by radionuclide ventriculography have been compared and their reproducibility assessed in a patient group. The methods studied were a geometric method, ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Thorley PJ,Sheard KL,Rees MR

    更新日期:1993-02-01 00:00:00

  • A wireless platform for in vivo measurement of resistance properties of the gastrointestinal tract.

    abstract::Active locomotion of wireless capsule endoscopes has the potential to improve the diagnostic yield of this painless technique for the diagnosis of gastrointestinal tract disease. In order to design effective locomotion mechanisms, a quantitative measure of the propelling force required to effectively move a capsule in...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Natali CD,Beccani M,Obstein KL,Valdastri P

    更新日期:2014-07-01 00:00:00

  • Length and activation dependent variations in muscle shear wave speed.

    abstract::Muscle stiffness is known to vary as a result of a variety of disease states, yet current clinical methods for quantifying muscle stiffness have limitations including cost and availability. We investigated the capability of shear wave elastography (SWE) to measure variations in gastrocnemius shear wave speed induced v...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Chernak LA,DeWall RJ,Lee KS,Thelen DG

    更新日期:2013-06-01 00:00:00

  • A phantom for evaluating bone mineral density of the hand by dual-energy x-ray absorptiometry.

    abstract::Dual-energy x-ray absorptiometry (DXA) is a precise, widely used method for measuring bone mineral density (BMD), usually of the lumbar spine and femoral neck. Recent developments, such as a lower x-ray tube current and pixel by pixel analysis, enable smaller bones and thinner tissues volumes, as in the hand, to be me...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Steel SA,Swann P,Langley G,Langton CM

    更新日期:1997-08-01 00:00:00

  • Energy scavenging sources for biomedical sensors.

    abstract::Energy scavenging has increasingly become an interesting option for powering electronic devices because of the almost infinite lifetime and the non-dependence on fuels for energy generation. Moreover, the rise of wireless technologies promises new applications in medical monitoring systems, but these still face limita...

    journal_title:Physiological measurement

    pub_type: 杂志文章,评审


    authors: Romero E,Warrington RO,Neuman MR

    更新日期:2009-09-01 00:00:00

  • The measurement of sedentary patterns and behaviors using the activPAL™ Professional physical activity monitor.

    abstract::Epidemiological studies have associated the negative effects of sedentary time and sedentary patterns on health indices. However, these studies have used methodologies that do not directly measure the sedentary state. Recent technological developments in the area of motion sensors have incorporated inclinometers, whic...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Dowd KP,Harrington DM,Bourke AK,Nelson J,Donnelly AE

    更新日期:2012-11-01 00:00:00

  • Exposure to light and darkness and its influence on physiological measures of intensive care unit patients-a systematic literature review.

    abstract::Sleep-wake patterns are often significantly disturbed in critically ill patients. This disturbance is closely linked to secondary brain dysfunctions in these patients. Sedation not only impairs sleep quality in ICU patients but also has detrimental effects on short- and long-term outcome. In other contexts, light ther...

    journal_title:Physiological measurement

    pub_type: 杂志文章,评审


    authors: Weiss B,Spies C,Piazena H,Penzel T,Fietze I,Luetz A

    更新日期:2016-09-01 00:00:00

  • A multi-frequency EIT system design based on telecommunication signal processors.

    abstract::A multi-frequency electrical impedance tomography system for cardiopulmonary monitoring has been designed with specialized digital signal processors developed primarily for the telecommunications sector. The system consists of two modules: a scan-head and a base-station. The scan-head, located close to the patient's t...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Robitaille N,Guardo R,Maurice I,Hartinger AE,Gagnon H

    更新日期:2009-06-01 00:00:00

  • Development of a novel method for assessing balance: the quantitative posturography system.

    abstract::Balance is the ability to maintain equilibrium while sitting or standing. There are a number of different methods which are used to assess balance: technical methods such as sway magnetometry, ataxia meter and force platforms, and clinical methods such as the functional reach test, Berg balance test and fall risk inde...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Browne J,O'Hare N

    更新日期:2000-11-01 00:00:00

  • Decomposition method of an electrical bio-impedance signal into cardiac and respiratory components.

    abstract::The paper presents a method for adaptive decomposition of an electrical bio-impedance (BI) signal into two components: cardiac and respiratory. The decomposition of a BI signal is not a trivial process because of the non-stationarity of the signal components and overlapping of their harmonic spectra. An application sp...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Krivoshei A,Kukk V,Min M

    更新日期:2008-06-01 00:00:00

  • Classification of cognitive reserve in healthy older adults based on brain activity using support vector machine.

    abstract:OBJECTIVE:Cognitive reserve (CR) refers to the capacity of the brain to actively cope with damage via the implementation of remedial cognitive processes. Traditional CR measurements focus on static proxies, which may not be able to appropriately estimate dynamic changes in CR. This study therefore investigated the cogn...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Yang CY,Lin CP

    更新日期:2020-07-07 00:00:00

  • Obstructive sleep apnea-hypopnea results in significant variations in cerebral hemodynamics detected by diffuse optical spectroscopies.

    abstract::The objective of this study was to adapt a novel near-infrared diffuse correlation spectroscopy (DCS) flow-oximeter for simultaneous and continuous monitoring of relative changes in cerebral blood flow (rCBF) and cerebral oxygenation (i.e. oxygenated/deoxygenated/total hemoglobin concentration: Δ[HbO2]/Δ[Hb]/ΔTHC) dur...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Hou Y,Shang Y,Cheng R,Zhao Y,Qin Y,Kryscio R,Rayapati A,Hayes D,Yu G

    更新日期:2014-10-01 00:00:00

  • Patient-specific simulations and measurements of the magneto-hemodynamic effect in human primary vessels.

    abstract::This paper investigates the main characteristics of the magneto-hemodynamic (MHD) response for application as a biomarker of vascular blood flow. The induced surface potential changes of a volunteer exposed to a 3 T static B0 field of a magnetic resonance imaging (MRI) magnet were measured over time at multiple locati...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Kyriakou A,Neufeld E,Szczerba D,Kainz W,Luechinger R,Kozerke S,McGregor R,Kuster N

    更新日期:2012-02-01 00:00:00

  • Airway resistance estimation by best fit analysis in very premature infants.

    abstract::Plethysmographic measurement of airway resistance (R(aw)) has been determined by single-point analysis, usually at 50% of maximum inspiratory flow (MIF). Computer-assisted (best fit) analysis, however, allows R(aw) to be calculated by applying a regression line to any portion of the plethysmograph pressure-flow loop. ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Thomas M,Greenough A,Blowes R,Rafferty GF,Calvert S,Marlow N,Peacock JL,Milner AD

    更新日期:2002-05-01 00:00:00

  • Hidden Markov model-based activity recognition for toddlers.

    abstract:OBJECTIVE:Physical activity has been shown to impact future health outcomes in adults, but little is known about the long-term impact of physical activity in toddlers. Accurately measuring the specific types and amounts of physical activity in toddlers will help us to understand, predict, and better affect their future...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Albert MV,Sugianto A,Nickele K,Zavos P,Sindu P,Ali M,Kwon S

    更新日期:2020-03-06 00:00:00

  • Patient examinations using electrical impedance tomography--sources of interference in the intensive care unit.

    abstract::Electrical impedance tomography (EIT) is expected to become a valuable tool for monitoring mechanically ventilated patients due to its ability to continuously assess regional lung ventilation and aeration. Several sources of interference with EIT examinations exist in intensive care units (ICU). Our objectives are to ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Frerichs I,Pulletz S,Elke G,Gawelczyk B,Frerichs A,Weiler N

    更新日期:2011-12-01 00:00:00

  • Pulmonary perfusion measured by means of electrical impedance tomography.

    abstract::Electrical impedance tomography (EIT) is a recent imaging technique based on electrical impedance, offering the possibility of measuring pulmonary perfusion. In the present study the influence of several pulmonary haemodynamical parameters on the EIT signal were investigated. First, the influence on the systolic wave ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Vonk Noordegraaf A,Kunst PW,Janse A,Marcus JT,Postmus PE,Faes TJ,de Vries PM

    更新日期:1998-05-01 00:00:00

  • Direct EIT Jacobian calculations for conductivity change and electrode movement.

    abstract::Electrical impedance tomography (EIT) is very sensitive to deformations of the medium boundary shape. For lung imaging, breathing and changes in posture move the electrodes and change the chest shape, resulting in image artefacts. Several approaches have been proposed to improve the reconstructed images; most methods ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Gómez-Laberge C,Adler A

    更新日期:2008-06-01 00:00:00

  • Eye-tracker algorithms to detect saccades during static and dynamic tasks: a structured review.

    abstract:OBJECTIVE:Eye-tracking devices have become widely used as clinical assessment tools in a variety of applied-scientific fields to measure saccadic eye movements. With the emergence of multiple static and dynamic devices, the concurrent need for algorithm development and validation is paramount. APPROACH:This review ass...

    journal_title:Physiological measurement

    pub_type: 杂志文章,评审


    authors: Stuart S,Hickey A,Vitorio R,Welman K,Foo S,Keen D,Godfrey A

    更新日期:2019-02-26 00:00:00

  • Head and pelvis stride-to-stride oscillations in gait: validation and interpretation of measurements from wearable accelerometers.

    abstract::Unstable gait is a risk factor for falls. Wearable accelerometers enable remote monitoring of daily walking. Here, new methods for measuring stride-to-stride oscillations are validated against optical motion capture, normative data determined, and dependency on walking speed investigated. Walks by 13 young people (mea...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Brodie MA,Beijer TR,Canning CG,Lord SR

    更新日期:2015-05-01 00:00:00

  • Physiological motion monitoring: a wearable device and adaptative algorithm for sit-to-stand timing detection.

    abstract::A simple wearable device for sit-to-stand timing detection was designed and constructed with rate gyroscopes and accelerometers and a dedicated adaptive algorithm. The method was validated by comparison with optoelectronic equipment. Results from the comparison showed a maximal error always lower than 2.5 x 10(-2) s f...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Giansanti D,Maccioni G

    更新日期:2006-08-01 00:00:00

  • Localization of sources of brain alpha/theta/delta activity and the influence of the mode of spontaneous mentation.

    abstract::A method is described that accounts for multichannel brain field data (EEG) epochs, after transformation into the frequency domain, by a single oscillating dipole source in terms of phase angles. The method produces a potential distribution for each frequency point ('FFT dipole approximation'). These maps can be subje...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Michel CM,Henggeler B,Brandeis D,Lehmann D

    更新日期:1993-11-01 00:00:00

  • Infrared thermography for indirect assessment of activation of brown adipose tissue in lean and obese male subjects.

    abstract::Brown adipose tissue (BAT) plays a key role in adaptive thermogenesis in mammals, and it has recently been considered as an attractive therapeutic target for tackling human obesity by increasing energy expenditure. Thermal imaging using infrared thermography (IRT) has emerged as a potential safe, rapid and inexpensive...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: El Hadi H,Frascati A,Granzotto M,Silvestrin V,Ferlini E,Vettor R,Rossato M

    更新日期:2016-12-01 00:00:00

  • Comprehensive analysis of cardiac health using heart rate signals.

    abstract::The electrocardiogram is a representative signal containing information about the condition of the heart. The shape and size of the P-QRS-T wave, the time intervals between its various peaks, etc may contain useful information about the nature of disease affecting the heart. However, the human observer cannot directly...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Acharya U R,Kannathal N,Krishnan SM

    更新日期:2004-10-01 00:00:00

  • Fetal QRS detection and heart rate estimation: a wavelet-based approach.

    abstract::Fetal heart rate monitoring is used for pregnancy surveillance in obstetric units all over the world but in spite of recent advances in analysis methods, there are still inherent technical limitations that bound its contribution to the improvement of perinatal indicators. In this work, a previously published wavelet t...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Almeida R,Gonçalves H,Bernardes J,Rocha AP

    更新日期:2014-08-01 00:00:00