Dynamics of tissue shrinkage during ablative temperature exposures.

Abstract:

:There is a lack of studies that examine the dynamics of heat-induced shrinkage of organ tissues. Clinical procedures such as radiofrequency ablation, microwave ablation or high-intensity focused ultrasound, use heat to treat diseases such as cancer and cardiac arrhythmia. When heat is applied to tissues, shrinkage occurs due to protein denaturation, dehydration and contraction of collagen at temperatures greater 50 °C. This is particularly relevant for image-guided procedures such as tumor ablation, where pre- and post-treatment images are compared and any changes in dimensions must be considered to avoid misinterpretations of the treatment outcome. We present data from ex vivo, isothermal shrinkage tests in porcine liver tissue, where axial changes in tissue length were recorded during 15 min of heating to temperatures between 60 and 95 °C. A mathematical model was developed to accurately describe the time and temperature-dependent shrinkage behavior. The shrinkage dynamics had the same characteristics independent of temperature; the estimated relative shrinkage, adjusted for time since death, after 15 min heating to temperatures of 60, 65, 75, 85 and 95 °C, was 12.3, 13.8, 16.6, 19.2 and 21.7%, respectively. Our results demonstrate the shrinkage dynamics of organ tissues, and suggest the importance of considering tissue shrinkage for thermal ablative treatments.

journal_name

Physiol Meas

authors

Rossmann C,Garrett-Mayer E,Rattay F,Haemmerich D

doi

10.1088/0967-3334/35/1/55

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

55-67

issue

1

eissn

0967-3334

issn

1361-6579

journal_volume

35

pub_type

杂志文章
  • The influence of cardiac preload and positive end-expiratory pressure on the pre-ejection period.

    abstract::The pre-ejection period (PEP) has recently been described as a potential parameter for monitoring cardiac preload. This study further investigated the influence of changes in intravascular volume status and the application of positive end-expiratory pressure (PEEP) on the pre-ejection period. In ten pigs, ECG, arteria...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/26/6/012

    authors: Kubitz JC,Kemming GI,Schultheib G,Starke J,Podtschaske A,Goetz AE,Reuter DA

    更新日期:2005-12-01 00:00:00

  • In vivo neutron activation analysis of bone manganese in workers.

    abstract:OBJECTIVE:Manganese (Mn) is a neurotoxin. However, the impact of elevated, chronic Mn exposure is not well understood, partially due to the lack of a cumulative exposure biomarker. To address this gap, our group developed a compact in vivo neutron activation analysis (IVNAA) system to quantify Mn concentration in bone ...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/1361-6579/aaa749

    authors: Liu Y,Rolle-McFarland D,Mostafaei F,Zhou Y,Li Y,Zheng W,Wells E,Nie LH

    更新日期:2018-03-23 00:00:00

  • EIT data noise evaluation in the clinical environment.

    abstract::In the clinical environment the reliable interpretation of EIT images depends on the quality of the data. In the electrically noisy hospital environment the system performance needs to be assessed for each clinical investigation. From the model of noise presented, a figure of merit for comparisons of system performanc...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/17/4a/006

    authors: Meeson S,Blott BH,Killingback AL

    更新日期:1996-11-01 00:00:00

  • Patient-specific simulations and measurements of the magneto-hemodynamic effect in human primary vessels.

    abstract::This paper investigates the main characteristics of the magneto-hemodynamic (MHD) response for application as a biomarker of vascular blood flow. The induced surface potential changes of a volunteer exposed to a 3 T static B0 field of a magnetic resonance imaging (MRI) magnet were measured over time at multiple locati...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/33/2/117

    authors: Kyriakou A,Neufeld E,Szczerba D,Kainz W,Luechinger R,Kozerke S,McGregor R,Kuster N

    更新日期:2012-02-01 00:00:00

  • Generalizability of extracellular-to-intracellular fluid ratio using bio-impedance spectroscopy.

    abstract::Generalizability theory was used to investigate the score consistency of observed extracellular fluid/intracellular fluid (ECF/ICF) ratio measurements for both the global and leg-segmental bio-impedance spectroscopy methods. The test instrument used was a Xitron Hydra ECF/ICF Bio-Impedance Analyzer System, model 4200 ...

    journal_title:Physiological measurement

    pub_type: 杂志文章,随机对照试验

    doi:10.1088/0967-3334/27/4/005

    authors: Turner AA,Lozano-Nieto A,Bouffard M

    更新日期:2006-04-01 00:00:00

  • Determination of Cole parameters in multiple frequency bioelectrical impedance analysis using only the measurement of impedances.

    abstract::Conventional bioimpedance spectrometers measure resistance and reactance over a range of frequencies and, by application of a mathematical model for an equivalent circuit (the Cole model), estimate resistance at zero and infinite frequencies. Fitting of the experimental data to the model is accomplished by iterative, ...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/27/9/007

    authors: Ward LC,Essex T,Cornish BH

    更新日期:2006-09-01 00:00:00

  • A measurement of pulmonary blood volume increase during systole in humans.

    abstract::Pulmonary blood volume increase during systole was measured in patients by analysing chest images obtained during ECG gated radionuclide angiography examination. The difference in the total radiation counts between systole and diastole in regions of interest, which included the lungs and the left ventricle, was measur...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章

    doi:10.1088/0967-3334/15/4/010

    authors: Nitzan M,Mahler Y,Schechter D,Yaffe S,Bocher M,Chisin R

    更新日期:1994-11-01 00:00:00

  • Identification of oxygen-19 during in vivo neutron activation analysis of water phantoms.

    abstract::Hand bone equivalent phantoms (250 ml) carrying selenium in various amounts were irradiated and counted for in vivo neutron activation analysis (IVNAA) by employing a 4π NaI(TI) based detection system. During the analysis of counting data, a feature at a higher energy than the gamma ray peak from (77m)Se (0.162 MeV) w...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/36/12/N127

    authors: Tahir SN,Chettle DR

    更新日期:2015-12-01 00:00:00

  • Empirical mode decomposition analysis of HRV data from patients undergoing local anaesthesia (brachial plexus block).

    abstract::Spectral analysis of heart rate variability (HRV) is used for the assessment of cardiovascular autonomic control. In this study, a data-driven adaptive technique called empirical mode decomposition (EMD) and the associated Hilbert spectrum has been used to evaluate the effect of local anaesthesia on HRV parameters in ...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章

    doi:10.1088/0967-3334/32/4/008

    authors: Shafqat K,Pal SK,Kumari S,Kyriacou PA

    更新日期:2011-04-01 00:00:00

  • A pH-mucosa area unit of measure to consider morphology of the oesophagus when evaluating oesophagitis.

    abstract::Gastro-oesophageal pH measurements are routinely carried out to quantify and determine if levels of acid reflux are responsible for symptoms. Although considered the 'gold standard', evidence suggests that pH measurements do not correlate well with the degree of oesophagitis seen during endoscopy. In this study the cu...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章

    doi:10.1088/0967-3334/24/4/006

    authors: Haylett KR,Vales P,Lee SH,McCloy RF

    更新日期:2003-11-01 00:00:00

  • Permutation Lempel-Ziv complexity measure of electroencephalogram in GABAergic anaesthetics.

    abstract::Monitoring the brain state in anaesthesia is crucial for clinical doctors. In this study, we propose a novel nonlinear method, the permutation Lempel-Ziv complexity (PLZC) index, which describes the complexity in the electroencephalographic (EEG) signal to quantify the effect of GABAergic anaesthetics on brain activit...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/36/12/2483

    authors: Bai Y,Liang Z,Li X,Voss LJ,Sleigh JW

    更新日期:2015-12-01 00:00:00

  • Effects of awareness and nociception on heart rate variability during general anaesthesia.

    abstract::During anaesthesia awareness and nociception are serious complications that may further lead to haemodynamic instability. Specific monitoring of depth of hypnosis and depth of analgesia based on heart rate variability (HRV) analysis is eligible to improve patient safety and reduce efforts in post-operative care. Conse...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章

    doi:10.1088/0967-3334/33/2/207

    authors: Huhle R,Burghardt M,Zaunseder S,Wessel N,Koch T,Malberg H,Heller AR

    更新日期:2012-02-01 00:00:00

  • Phase shift between respiratory oscillations in cerebral blood flow velocity and arterial blood pressure.

    abstract::We aim to investigate whether phase shift between respiratory oscillations in cerebral blood flow velocity (CBFV) and arterial blood pressure (ABP) is associated with changes in cerebral autoregulation (CA) or reflects the mechano-elastic properties of the cerebrovascular bed. The relationships between respiratory pha...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/1361-6579/38/2/310

    authors: Uryga A,Placek MM,Wachel P,Szczepański T,Czosnyka M,Kasprowicz M

    更新日期:2017-02-01 00:00:00

  • Non-contact video-based vital sign monitoring using ambient light and auto-regressive models.

    abstract::Remote sensing of the reflectance photoplethysmogram using a video camera typically positioned 1 m away from the patient's face is a promising method for monitoring the vital signs of patients without attaching any electrodes or sensors to them. Most of the papers in the literature on non-contact vital sign monitoring...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/35/5/807

    authors: Tarassenko L,Villarroel M,Guazzi A,Jorge J,Clifton DA,Pugh C

    更新日期:2014-05-01 00:00:00

  • Tracking boundary movement and exterior shape modelling in lung EIT imaging.

    abstract::Electrical impedance tomography (EIT) has shown significant promise for lung imaging. One key challenge for EIT in this application is the movement of electrodes during breathing, which introduces artefacts in reconstructed images. Various approaches have been proposed to compensate for electrode movement, but no comp...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/36/6/1119

    authors: Biguri A,Grychtol B,Adler A,Soleimani M

    更新日期:2015-06-01 00:00:00

  • Multichannel simultaneous magnetic induction measurement system (MUSIMITOS).

    abstract::Non-contact heart and lung activity monitoring would be a desirable supplement to conventional monitoring techniques. Based on the potential of non-contact magnetic induction measurements, requirements for an adequate monitoring system were estimated. This formed the basis for the development of the presented extendab...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/29/6/S25

    authors: Steffen M,Heimann K,Bernstein N,Leonhardt S

    更新日期:2008-06-01 00:00:00

  • Coupling between arterial pressure, cerebral blood velocity, and cerebral tissue oxygenation with spontaneous and forced oscillations.

    abstract::We tested the hypothesis that transmission of arterial pressure to brain tissue oxygenation is low under conditions of arterial pressure instability. Two experimental models of hemodynamic instability were used in healthy human volunteers; (1) oscillatory lower body negative pressure (OLBNP) (N = 8; 5 male, 3 female),...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/36/4/785

    authors: Rickards CA,Sprick JD,Colby HB,Kay VL,Tzeng YC

    更新日期:2015-04-01 00:00:00

  • Magnetographic assessment of fetal hiccups and their effect on fetal heart rhythm.

    abstract::Fetal hiccups emerge as early as nine weeks post-conception, being the predominant diaphragmatic movement before 26 weeks of gestation. They are considered as a programmed isometric inspiratory muscle exercise of the fetus in preparation for the post-natal respiratory function, or a manifestation of a reflex circuitry...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/28/6/005

    authors: Popescu EA,Popescu M,Bennett TL,Lewine JD,Drake WB,Gustafson KM

    更新日期:2007-06-01 00:00:00

  • The impact of electrode area, contact impedance and boundary shape on EIT images.

    abstract::Electrical impedance tomography (EIT) measures the conductivity distribution within an object based on the current applied and voltage measured at surface electrodes. Thus, EIT images are sensitive to electrode properties (i.e. contact impedance, electrode area and boundary shape under the electrode). While some of th...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/32/7/S02

    authors: Boyle A,Adler A

    更新日期:2011-07-01 00:00:00

  • Dynamic time warping and machine learning for signal quality assessment of pulsatile signals.

    abstract::In this work, we describe a beat-by-beat method for assessing the clinical utility of pulsatile waveforms, primarily recorded from cardiovascular blood volume or pressure changes, concentrating on the photoplethysmogram (PPG). Physiological blood flow is nonstationary, with pulses changing in height, width and morphol...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/33/9/1491

    authors: Li Q,Clifford GD

    更新日期:2012-09-01 00:00:00

  • Fetal beat detection in abdominal ECG recordings: global and time adaptive approaches.

    abstract::We present a method for location of fetal QRS in maternal abdominal ECG recordings. This method's initial, global approach was proposed in the context of the 2013 PhysioNet/Computing in Cardiology Challenge where it was tested on the 447 four channel one-minute recordings.The first step is filtering to eliminate basel...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/35/8/1699

    authors: Rodrigues R

    更新日期:2014-08-01 00:00:00

  • Validation of a finite-element solution for electrical impedance tomography in an anisotropic medium.

    abstract::Electrical impedance tomography is an imaging method, with which volumetric images of conductivity are produced by injecting electrical current and measuring boundary voltages. It has the potential to become a portable non-invasive medical imaging technique. Until now, implementations have neglected anisotropy even th...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/28/7/S10

    authors: Abascal JF,Arridge SR,Lionheart WR,Bayford RH,Holder DS

    更新日期:2007-07-01 00:00:00

  • Physiological motion monitoring: a wearable device and adaptative algorithm for sit-to-stand timing detection.

    abstract::A simple wearable device for sit-to-stand timing detection was designed and constructed with rate gyroscopes and accelerometers and a dedicated adaptive algorithm. The method was validated by comparison with optoelectronic equipment. Results from the comparison showed a maximal error always lower than 2.5 x 10(-2) s f...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/27/8/006

    authors: Giansanti D,Maccioni G

    更新日期:2006-08-01 00:00:00

  • Classification of glucose concentration in diluted urine using the low-resolution Raman spectroscopy and kernel optimization methods.

    abstract::In order to detect minute amounts of glucose in diluted urine, we applied the Raman spectroscopy method. To simulate abnormal diluted urine in a toilet bowl, we diluted normal urine ten-fold with water and added glucose up to 8 mg dl(-1). Data were collected using a low-resolution Raman spectrometer that was preproces...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/28/5/011

    authors: Park C,Kim K,Choi J,Park K

    更新日期:2007-05-01 00:00:00

  • Aging in autonomic control by multifractal studies of cardiac interbeat intervals in the VLF band.

    abstract::The heart rate responds dynamically to various intrinsic and environmental stimuli. The autonomic nervous system is said to play a major role in this response. Multifractal analysis offers a novel method to assess the response of cardiac interbeat intervals. Twenty-four hour ECG recordings of RR interbeat intervals (o...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/32/10/014

    authors: Makowiec D,Rynkiewicz A,Wdowczyk-Szulc J,Zarczyńska-Buchowiecka M,Gałaska R,Kryszewski S

    更新日期:2011-10-01 00:00:00

  • An analytic solution to the homogeneous EIT problem on the 2D disk and its application to estimation of electrode contact impedances.

    abstract::An analytic solution of the potential distribution on a 2D homogeneous disk for electrical impedance tomography under the complete electrode model is expressed via an infinite system of linear equations. For the shunt electrode model with two electrodes, our solution coincides with the previously derived solution expr...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/32/9/008

    authors: Demidenko E

    更新日期:2011-09-01 00:00:00

  • Gastric activity studies using a magnetic tracer.

    abstract::A magnetic pulse generator has been set up in order to study gastric activity. Two coils 1.05 m in diameter, arranged in a Helmholtz configuration, were used. The system generated magnetic field pulses higher than 15 mT, of duration 17.3+/-1.2 ms. Measurements were performed in 11 male volunteers, with average age 29....

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章

    doi:10.1088/0967-3334/25/5/015

    authors: Cordova-Fraga T,Bernal-Alvarado JJ,Gutierrez-Juarez G,Sosa M,Vargas-Luna M

    更新日期:2004-10-01 00:00:00

  • Noise sensitivity of three surface ECG fibrillation detection algorithms.

    abstract::The widening application of automatic external defibrillators (AEDs) presents very strong requirements for external electrocardiogram (ECG) signal analysis. Highly accurate detection of shockable rhythms is required, aimed to approach the maximum of 100% sensitivity and specificity. In a previous study the performance...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/22/2/302

    authors: Jekova I,Cansell A,Dotsinsky I

    更新日期:2001-05-01 00:00:00

  • Topographic distribution of idiopathic pulmonary fibrosis: a hybrid physics- and agent-based model.

    abstract:OBJECTIVE:Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by excessive deposition of collagen and associated stiffening of lung tissue. While it is known that inflammation and dysfunction of fibroblasts are involved in disease development, it remains poorly understood how cells and ...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/1361-6579/aaca86

    authors: Wellman TJ,Mondoñedo JR,Davis GS,Bates JHT,Suki B

    更新日期:2018-06-28 00:00:00

  • Transthoracic electrical impedance during external defibrillation: comparison of measured and modelled waveforms.

    abstract::The transthoracic electrical impedance is an important defibrillation parameter, affecting the defibrillating current amplitude and energy, and therefore the defibrillation efficiency. A close relationship between transthoracic impedance and defibrillation success rate was observed. Pre-shock measurements (using low a...

    journal_title:Physiological measurement

    pub_type: 杂志文章

    doi:10.1088/0967-3334/21/1/318

    authors: Al Hatib F,Trendafilova E,Daskalov I

    更新日期:2000-02-01 00:00:00