Intracellular calcium localization in stimulated and non-stimulated extraorbital lacrimal glands of rats.

Abstract:

:Acinar cells of extraorbital lacrimal glands from control, pilocarpine-treated, atropine-treated and atropine + pilocarpine-treated rats were studied using a potassium pyroantimonate technique and X-ray microanalysis for calcium localization at the ultrastructural level. This was done in order to identify intracellular compartmentalization of calcium and to elucidate any calcium translocation that might occur during the secretory process. Calcium-pyroantimonate complexes were identified in the mitochondria, plasma membrane and cytoplasmic vesicles of the untreated specimens and in the plasma membrane of atropine-treated specimens, these complexes decreased drastically in the actively-secreting cells. The function of calcium in lacrimal gland secretion and the action of pilocarpine and atropine on membrane calcium are discussed.

journal_name

Tissue Cell

journal_title

Tissue & cell

authors

Sampson HW,Bowers DE,Cannon MS,Piscopo I

doi

10.1016/0040-8166(82)90062-3

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

735-49

issue

4

eissn

0040-8166

issn

1532-3072

journal_volume

14

pub_type

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