Abstract：
:Cellular aggregates or nodules which formed in Galleria mellonella larvae in response to injections of killed Bacillus cereus were examined during their first 24 hr of development. The initial aggregation stage was very rapid, occurring within 1 min, and was brought about by the release of an adhesive flocculent material by granular haemocytes in contact with the bacteria. This material, which subsequently became increasingly electron dense owing to melanin deposition, consolidated and by 5 min ramified all the intercellular spaces. The granular cells degenerated, releasing portions of cytoplasm form their peripheries, and eventurally appeared in the matrix as voids containing loosely flocculent material. No bacterial breakdown was seen, however. From 2-4 hr, plasmatocytes began to encapsulate the necrotic mass, and by 24 hr a complete sheath, composed of three discrete regions of cells, was formed. These findings are discussed in relation to the various proposed mechanisms of nodule and capsule formation.
journal_name
Tissue Celljournal_title
Tissue & cellauthors
Ratcliffe NA,Gagen SJdoi
10.1016/0040-8166(77)90050-7subject
Has Abstractpub_date
1977-01-01 00:00:00pages
73-85issue
1eissn
0040-8166issn
1532-3072pii
0040-8166(77)90050-7journal_volume
9pub_type
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